Page last updated: 2024-08-17

nad and Koch's Disease

nad has been researched along with Koch's Disease in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (51.52)	18.7374
1990's	1 (3.03)	18.2507
2000's	6 (18.18)	29.6817
2010's	7 (21.21)	24.3611
2020's	2 (6.06)	2.80

Authors

Authors	Studies
Agarwal, A; Chinta, KC; Glasgow, JN; Lumamba, K; Nadeem, S; Naidoo, T; Nargan, K; Pacl, HT; Reddy, VP; Sevalkar, RR; Steyn, AJC	1
Ferraris, DM; Garavaglia, S; Gelardi, ELM; Miggiano, R; Rizzi, M	1
Crans, DC; Crick, DC; Koehn, JT; Kumar, S; Lott, JS; McNeil, MR; Rooker, SA; Upadhyay, A	1
Muronetz, VI; Schmalhausen, EV; Shumkov, MS; Švedas, VK	1
Ariyachaokun, K; Beckham, KSH; Botella, L; Boudehen, YM; Cianci, M; Colom, A; de Carvalho, LPS; Freire, DM; Garza-Garcia, A; Genevaux, P; Grabowska, AD; Gutierrez, C; Neyrolles, O; Panikova, T; Parret, AHA; Peixoto, A; Pogenberg, V; Sala, AJ; Schnappinger, D; Schneider, TR; Svergun, DI; Tuukkanen, A; Wilmanns, M	1
Deshmukh, S; Harinath, BC; Jena, L; Kumar, S; Waghmare, P	1
Penberthy, WT	1
Miller, CL	1
Chen, B; Jacobs, WR; Vilchèze, C; Weinrick, B; Wong, KW	1
Singh, V; Somvanshi, P	1
Bernadou, J; Bernardes-Génisson, V; Constant, P; Delaine, T; Meunier, B; Quémard, A	1
PATIALA, J	1
KERPPOLA, W; PATIALA, J	1
ARTMAN, M; BEKIERKUNST, A	1
ARTMAN, M; BEKIERKUNST, A; WINDMAN, I	1
ARTMAN, M; BEKIERKUNST, A; SILMAN, N	1
ALEXANDER, N; ARTMAN, M; BEKIERKUNST, A	1
GOPINATHAN, KP; SIRSI, M; VAIDYANATHAN, CS	1
Bernadou, J; Bernardes-Génisson, V; Broussy, S; Gornitzka, H; Meunier, B	1
Basso, LA; de Sousa, EH; de Souza, ON; Moreira, IS; Oliveira, JS; Santos, DS	1
Besra, GS; Dover, LG; Gulten, G; Jacobs, WR; Langley, R; Sacchettini, JC; Wang, F	1
Barry, CE; Boshoff, HI; Camacho, LR; Dowd, CS; Ehrt, S; Park, TH; Pethe, K; Schnappinger, D; Tahlan, K; Williams, KJ; Xu, X; Yun, CS	1
Basso, LA; Blanchard, JS; Jacobs, WR; Musser, JM; Zheng, R	1
Martin, SP; Mathur, PP; Shah, NS	2
Shah, NS	2
Bekierkunst, A	1
Ando, F; Toida, I; Yamamoto, S	3
Bekierkunst, A; Windman, I	2

Reviews

2 review(s) available for nad and Koch's Disease

Article	Year
Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer. Biochemical Society transactions, 2020, 04-29, Volume: 48, Issue:2 Topics: Aldehyde Oxidoreductases; Animals; Antimalarials; Antitubercular Agents; Communicable Diseases; Drug Design; Drug Discovery; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Inhibins; Isoenzymes; Malaria; NAD; Neoplasms; Oxidoreductases; Tuberculosis	2020
Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex. Current pharmaceutical design, 2006, Volume: 12, Issue:19 Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Humans; Isoniazid; Kinetics; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis	2006

Article

Year

Targeting NAD-dependent dehydrogenases in drug discovery against infectious diseases and cancer.

Biochemical Society transactions, 2020, 04-29, Volume: 48, Issue:2

Topics: Aldehyde Oxidoreductases; Animals; Antimalarials; Antitubercular Agents; Communicable Diseases; Drug Design; Drug Discovery; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Inhibins; Isoenzymes; Malaria; NAD; Neoplasms; Oxidoreductases; Tuberculosis

2020

Slow-onset inhibition of 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis by an inorganic complex.

Current pharmaceutical design, 2006, Volume: 12, Issue:19

Topics: Antitubercular Agents; Bacterial Proteins; Drug Design; Humans; Isoniazid; Kinetics; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis

2006

Other Studies

31 other study(ies) available for nad and Koch's Disease

Article	Year
NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis. Nature communications, 2023, 09-06, Volume: 14, Issue:1 Topics: Animals; Glycolysis; Homeostasis; Lactate Dehydrogenase 5; Mice; Myeloid Cells; NAD; Niacinamide; Tuberculosis	2023
Mycobacterial MenJ: An Oxidoreductase Involved in Menaquinone Biosynthesis. ACS chemical biology, 2018, 09-21, Volume: 13, Issue:9 Topics: Bacterial Proteins; Biosynthetic Pathways; Flavin-Adenine Dinucleotide; Humans; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Oxidoreductases; Recombinant Proteins; Tuberculosis; Ubiquinone; Vitamin K 2	2018
Expression of glyceraldehyde-3-phosphate dehydrogenase from M. tuberculosis in E. coli. Purification and characteristics of the untagged recombinant enzyme. Protein expression and purification, 2019, Volume: 157 Topics: Amino Acid Sequence; Cloning, Molecular; Escherichia coli; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Mycobacterium tuberculosis; NAD; Protein Folding; Recombinant Proteins; Sequence Alignment; Tuberculosis	2019
An NAD Molecular cell, 2019, 03-21, Volume: 73, Issue:6 Topics: Animals; Antibiotics, Antitubercular; Antitoxins; Bacterial Load; Bacterial Proteins; Bacterial Toxins; Cells, Cultured; Disease Models, Animal; Female; Host-Pathogen Interactions; Humans; Kinetics; Macrophages; Mice, Inbred C57BL; Mice, SCID; Mice, Transgenic; Microbial Viability; Models, Molecular; Mycobacterium smegmatis; Mycobacterium tuberculosis; NAD; Phosphorylases; Protein Conformation; Toxin-Antitoxin Systems; Tuberculosis	2019
Study of mechanism of interaction of truncated isoniazid-nicotinamide adenine dinucleotide adduct against multiple enzymes of Mycobacterium tuberculosis by a computational approach. International journal of mycobacteriology, 2015, Volume: 4, Issue:4 Topics: Antitubercular Agents; Bacterial Proteins; Humans; Isoniazid; Molecular Docking Simulation; Mycobacterium tuberculosis; NAD; Tuberculosis	2015
Nicotinamide adenine dinucleotide biology and disease. Current pharmaceutical design, 2009, Volume: 15, Issue:1 Topics: Cardiovascular Diseases; Diabetes Mellitus; Humans; Multiple Sclerosis; NAD; Neoplasms; Schizophrenia; Tuberculosis	2009
The evolution of schizophrenia: a model for selection by infection, with a focus on NAD. Current pharmaceutical design, 2009, Volume: 15, Issue:1 Topics: Biological Evolution; Humans; Kynurenine; Models, Biological; NAD; Schizophrenia; Selection, Genetic; Tuberculosis	2009
NAD+ auxotrophy is bacteriocidal for the tubercle bacilli. Molecular microbiology, 2010, Volume: 76, Issue:2 Topics: Animals; Biosynthetic Pathways; Colony Count, Microbial; Disease Models, Animal; Mice; Microbial Viability; Models, Biological; Mycobacterium bovis; Mycobacterium tuberculosis; NAD; Niacinamide; Tuberculosis; Virulence	2010
Toward the virtual screening of potential drugs in the homology modeled NAD+ dependent DNA ligase from Mycobacterium tuberculosis. Protein and peptide letters, 2010, Volume: 17, Issue:2 Topics: Amino Acid Sequence; Antitubercular Agents; Bacterial Proteins; Catalytic Domain; Computational Biology; Databases, Protein; DNA Ligases; Drug Design; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mycobacterium tuberculosis; NAD; Phylogeny; Protein Binding; Protein Conformation; Sequence Alignment; Sequence Homology, Amino Acid; Tuberculosis	2010
Development of isoniazid-NAD truncated adducts embedding a lipophilic fragment as potential bi-substrate InhA inhibitors and antimycobacterial agents. European journal of medicinal chemistry, 2010, Volume: 45, Issue:10 Topics: Antitubercular Agents; Bacterial Proteins; Humans; Isoniazid; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis	2010
The amount of pyridine nucleotides (coenzymes I and II) in blood in experimental tuberculosis before and during isoniazid treatment. American review of tuberculosis, 1954, Volume: 70, Issue:3 Topics: Coenzymes; Isomerism; Isoniazid; NAD; Niacin; Nicotinic Acids; Nucleotides; Tuberculosis	1954
Pyridinenucleotides (coenzyme I and II) of blood in normal subjects and in various diseases, especially tuberculosis. Annales medicinae experimentalis et biologiae Fenniae, 1954, Volume: 32, Issue:7 Topics: Blood; Humans; NAD; Nucleotides; Thoracic Cavity; Tuberculosis; Tuberculosis, Pulmonary	1954
Tissue metabolism in infection. DPNase activity, DPN levels, and DPN-linked dehydrogenases in tissues from normal and tuberculous mice. The American review of respiratory disease, 1962, Volume: 86 Topics: Animals; L-Lactate Dehydrogenase; Liver; Lung; Metabolism; Mice; NAD; NAD+ Nucleosidase; Nucleotidases; Oxidoreductases; Splenectomy; Tuberculosis	1962
PARTICULATE, SOLUBLE AND PLASMA NICOTINAMIDE-ADENINE DINUCLEOTIDE GLYCOHYDROLASE IN NORMAL AND TUBERCULOUS GUINEA-PIGS. Biochimica et biophysica acta, 1964, Feb-10, Volume: 82 Topics: Animals; Blood Chemical Analysis; Clinical Enzyme Tests; Glycoside Hydrolases; Guinea Pigs; Kidney; Liver; Lung; NAD; Plasma; Research; Spleen; Transferases; Tuberculosis	1964
TISSUE METABOLISM IN INFECTION. SOLUBLE NICOTINAMIDE-ADENINE DINUCLEOTIDASE IN ORGANS FROM TUBERCULOUS MICE. The American review of respiratory disease, 1964, Volume: 89 Topics: Adenine; Animals; Liver; Lung; Metabolism; Mice; Mycobacterium tuberculosis; NAD; Niacin; Niacinamide; Nucleotidases; Research; Tuberculosis	1964
NICOTINAMIDE ADENINE DINUCLEOTIDASE ACTIVITY IN CELLS OF TUBERCULOUS ANIMALS. Science (New York, N.Y.), 1964, Jul-17, Volume: 145, Issue:3629 Topics: Adenine; Animals; Guinea Pigs; Leukocytes; Lymphoid Tissue; Metabolism; Mice; Monocytes; NAD; Niacinamide; Nucleotidases; Research; Tuberculosis	1964
NICOTINAMIDE-ADENINE DINUCLEOTIDE-GLYCOHYDROLASE ACTIVITY IN EXPERIMENTAL TUBERCULOSIS. The Biochemical journal, 1965, Volume: 94 Topics: Animals; Biochemical Phenomena; Biochemistry; Chloromercuribenzoates; Enzyme Inhibitors; Ethylmaleimide; Isoniazid; Liver; Lung; Metabolism; Mice; N-Glycosyl Hydrolases; NAD; NAD+ Nucleosidase; Niacinamide; Research; Tuberculosis	1965
Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid-NAD adduct. Organic & biomolecular chemistry, 2005, Feb-21, Volume: 3, Issue:4 Topics: Crystallography, X-Ray; Humans; Isoniazid; Molecular Conformation; Molecular Structure; NAD; Niacin; Pyridines; Tuberculosis	2005
Mechanism of thioamide drug action against tuberculosis and leprosy. The Journal of experimental medicine, 2007, Jan-22, Volume: 204, Issue:1 Topics: Antitubercular Agents; Bacterial Proteins; Crystallography, X-Ray; Drug Design; Drug Resistance, Multiple, Bacterial; Ethionamide; Humans; In Vitro Techniques; Leprostatic Agents; Leprosy; Models, Molecular; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium leprae; Mycobacterium tuberculosis; NAD; Oxidoreductases; Prothionamide; Tuberculosis; Tuberculosis, Multidrug-Resistant	2007
Biosynthesis and recycling of nicotinamide cofactors in mycobacterium tuberculosis. An essential role for NAD in nonreplicating bacilli. The Journal of biological chemistry, 2008, Jul-11, Volume: 283, Issue:28 Topics: Animals; Genome, Bacterial; Homeostasis; Lung; Macrophages; Mice; Mutation; Mycobacterium tuberculosis; NAD; Oxidation-Reduction; Pentosyltransferases; Transcription, Genetic; Tuberculosis	2008
Mechanisms of isoniazid resistance in Mycobacterium tuberculosis: enzymatic characterization of enoyl reductase mutants identified in isoniazid-resistant clinical isolates. The Journal of infectious diseases, 1998, Volume: 178, Issue:3 Topics: Antitubercular Agents; Bacterial Proteins; Drug Resistance, Microbial; Humans; Isoniazid; Mutagenesis; Mutation; Mycobacterium tuberculosis; NAD; Oxidoreductases; Tuberculosis	1998
Actions of isoniazid on NADH dehydrogenase activity of kidney of tuberculous guinea pigs. Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:2 Topics: Animals; Guinea Pigs; In Vitro Techniques; Isoniazid; Kidney; NAD; Oxidoreductases; Tuberculosis	1966
Nicotinamide adenine dinucleotidase activity in experimental tuberculosis. Biochimica et biophysica acta, 1966, Mar-28, Volume: 117, Issue:1 Topics: Animals; Brain; Guinea Pigs; In Vitro Techniques; Kidney; Liver; N-Glycosyl Hydrolases; NAD; Spleen; Tuberculosis	1966
Subcellular distribution of nicotinamide adenine dinucleotidase in the spleen of tuberculous guinea pigs and tuberculous guinea pigs treated with isoniazid. The American review of respiratory disease, 1967, Volume: 96, Issue:1 Topics: Animals; Cell Nucleus; Centrifugation; Enzymes; Guinea Pigs; Isoniazid; Male; Microsomes; Mitochondria; NAD; Nucleotidases; Spleen; Tuberculosis	1967
Effect of isoniazid on preservation of nicotinamide dinucleotide in animal cells. Archives of biochemistry and biophysics, 1967, Mar-20, Volume: 118, Issue:3 Topics: Alcohol Oxidoreductases; Animals; Carcinoma, Ehrlich Tumor; Isoniazid; Liver; Lung; Mice; NAD; Nucleotidases; Spleen; Triaziquone; Tuberculosis	1967
[Biochemical study on the host response to tuberculous infection. 3. Significance of live tubercle bacilli to the metabolic changes of host]. Kekkaku : [Tuberculosis], 1967, Volume: 42, Issue:5 Topics: Animals; Cortisone; Female; Glycoside Hydrolases; Injections, Intravenous; Liver; Lung; Mice; Mycobacterium tuberculosis; NAD; Tuberculosis	1967
[Biochemical study on the host response to tuberculous infection. 2. NAD-ase of tuberculous mouse]. Kekkaku : [Tuberculosis], 1967, Volume: 42, Issue:4 Topics: Acid Phosphatase; Animals; Glycoside Hydrolases; Guinea Pigs; Mice; NAD; Succinate Dehydrogenase; Tuberculosis	1967
Biochemical study on the host response to tuberculous infection. IV. Influences of isoniazid, streptomycin, nicotinamide, and cortisone. The American review of respiratory disease, 1968, Volume: 98, Issue:3 Topics: Animals; Cortisone; Drug Resistance, Microbial; Isoniazid; Mice; Mycobacterium tuberculosis; N-Glycosyl Hydrolases; NAD; Niacinamide; Streptomycin; Tuberculosis	1968
Nicotinamide adenine dinucleotide levels and nadase activity in polymorphonuclear leukocytes, alveolar macrophages, and erythrocytes of tuberculous guinea pigs. The American review of respiratory disease, 1969, Volume: 100, Issue:2 Topics: Animals; Centrifugation; Erythrocytes; Guinea Pigs; Leukocytes; Macrophages; N-Glycosyl Hydrolases; NAD; Pulmonary Alveoli; Tuberculosis	1969
Oxidized and reduced forms of nicotinamide nucleotides in livers of tuberculous mice. The American review of respiratory disease, 1967, Volume: 96, Issue:2 Topics: Animals; Liver; Mice; NAD; NAD+ Nucleosidase; Oxidation-Reduction; Tuberculosis	1967
Isocitric dehydrogenase and nicotinamide adenine dinucleotidase in experimental tuberculosis: influence of isoniazid on metabolic damage. The American review of respiratory disease, 1967, Volume: 95, Issue:2 Topics: Animals; Guinea Pigs; Isocitrate Dehydrogenase; Isoniazid; Kidney; Male; NAD; NADP; Nucleotidases; Tuberculosis	1967