Page last updated: 2024-08-17

nad and Electron Transport Chain Deficiencies, Mitochondrial

nad has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.63)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (18.42)	29.6817
2010's	19 (50.00)	24.3611
2020's	11 (28.95)	2.80

Authors

Authors	Studies
Chandel, NS; Mithal, DS	1
Chen, W; Cong, L; Jiang, Y; Li, H; Sun, Y; Wang, H; Wang, Y; Xu, J; Yang, Q; Zhu, J	1
Carolino, K; Devanneaux, L; Farre, JC; Subramani, S	1
de Haas, R; Frambach, SJCM; Russel, FGM; Schirris, TJJ; Smeitink, JAM	1
Adant, I; Bird, M; Cassiman, D; de Witte, P; Decru, B; Ghesquière, B; Rymen, D; Vermeersch, P; Wallays, M; Windmolders, P; Witters, P	1
Chakraborty, S; Dey, P; Dutta, S; Mukherjee, P; Sarkar, A; Sur, M	1
Cao, T; Ding, W; Fan, GC; Ji, X; Ni, R; Peng, T; Zhang, Z	1
Escribano-Gonzalez, C; Favier, J; Goncalves, J; Hindshaw, RL; Kaul, B; Kľučková, K; Lavery, GG; Tearle, JLE; Tennant, DA; Thakker, A; Vettore, L	1
Gorman, GS; Lightowlers, RN; Russell, OM; Turnbull, DM	1
Xia, J; Xu, B; Zhao, N	1
Kretzschmar, T; Schulze, PC; Wu, JMF	1
Abramov, AY; Angelova, PR; Arber, C; Bhatia, KP; Duce, JA; Gout, I; Hardy, J; Houlden, H; Mazzacuva, F; Mills, K; Preza, E; Tsuchiya, Y; Wiethoff, S; Wray, S	1
Carruba, MO; Corsetti, G; Nisoli, E; Ragni, M; Rossi, F; Ruocco, C; Tedesco, L; Valerio, A	1
Krishnamurthy, S; Kumar, A; Narayan, G; Samaiya, PK	1
Baur, JA; Botolin, P; Davila, A; Guan, Y; Mukherjee, S; Sims, CA; Singh, K	1
Beyrath, J; Iannetti, EF; Koopman, WJH; Smeitink, JAM; Willems, PHGM	1
Adams, S; Castellano-Gonzalez, G; Cole, NJ; Don, E; Guillemin, GJ; Jacobs, KR; Lim, CK; Lovejoy, DB	1
Adanyeguh, I; Collins, B; Durr, A; Evans, RM; Fan, W; Ichou, F; Kinoshita, C; La Spada, AR; Mochel, F; Morrison, RS; Muotri, AR; Niu, C; Sopher, BL; Stoyas, CA; Switonski, PM; Wall, CE; Ward, JM	1
Baldassarro, VA; Bergamini, C; Bianco, F; Bonora, E; Buscherini, F; Cordelli, DM; Diaz, R; Diquigiovanni, C; Fato, R; Liparulo, I; Masin, L; Paracchini, S; Pippucci, T; Rizzardi, N; Scarano, E; Seri, M; Tranchina, A; Wischmeijer, A	1
Garcia-Menendez, L; Gong, G; Karamanlidis, G; Kolwicz, SC; Lee, CF; Morgan, PG; Sedensky, MM; Suthammarak, W; Tian, R; Wang, W	1
Nicolson, GL	1
Auwerx, J; Cerutti, R; Dantzer, F; Lamperti, C; Leoni, V; Li, W; Marchet, S; Pirinen, E; Sauve, AA; Schon, EA; Viscomi, C; Zeviani, M	1
Choo, HJ; Hong, J; Kim, BW; Ko, YG; Lee, H; Lee, JS; Park, JJ; Yi, JS; Yoon, GS; Yu, DM	1
Horn, P; Miles, L; Miles, MV; Rozhkov, L; Tenney, JR	1
Cracan, V; Goodman, RP; Grabarek, Z; Mootha, VK; Peng, J; Titov, DV	1
David, A; Guerra-Assunção, JA; Metherell, LA; Sternberg, MJ	1
Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D	1
Alano, CC; Garnier, P; Higashi, Y; Kauppinen, TM; Swanson, RA; Ying, W	1
Pandya, JD; Pettigrew, LC; Sullivan, PG	1
Arduino, DM; Cardoso, SM; Esteves, AR; Oliveira, CR; Silva, DF	1
Auwerx, J; Houtkooper, RH	1
Fink, MP	1
Copeland, WC; Dominick, OC; Graziewicz, MA; Longley, MJ; Strand, MK; Stuart, GR	1
GONATAS, NK; SHY, GM	1
Chance, B; Mayevsky, A	1
Chen, Y; Clark, RS; Guo, F; Jenkins, LW; Kochanek, PM; Lai, Y; Nathaniel, PD; Szabó, C; Watkins, SC	1
Bández, MJ; Boveris, A; Cadenas, E; Gómez, C; López-Cepero, JM; Navarro, A; Sánchez-Pino, MJ	1
Cairns, CB	1

Reviews

5 review(s) available for nad and Electron Transport Chain Deficiencies, Mitochondrial

Article	Year
Mitochondrial Diseases: Hope for the Future. Cell, 2020, 04-02, Volume: 181, Issue:1 Topics: Animals; DNA, Mitochondrial; Genetic Therapy; Genome, Mitochondrial; Humans; Mitochondria; Mitochondrial Diseases; Mutation; NAD; Reactive Oxygen Species	2020
Mitochondrial Homeostasis Mediates Lipotoxicity in the Failing Myocardium. International journal of molecular sciences, 2021, Feb-02, Volume: 22, Issue:3 Topics: Adipose Tissue; Calcium Signaling; Cardiomyopathies; Ceramides; Citric Acid Cycle; Disease Progression; Fatty Acids; Heart Failure; Homeostasis; Humans; Ketone Bodies; Mitochondria, Heart; Mitochondrial Diseases; Mitochondrial Dynamics; Mitophagy; NAD; Pericardium; Peroxisome Proliferator-Activated Receptors; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species	2021
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:11 Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan	2009
Bench-to-bedside review: Cytopathic hypoxia. Critical care (London, England), 2002, Volume: 6, Issue:6 Topics: Adenosine Triphosphate; Animals; Cell Respiration; Humans; Lipopolysaccharides; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Poly(ADP-ribose) Polymerases; Sepsis	2002
Rude unhinging of the machinery of life: metabolic approaches to hemorrhagic shock. Current opinion in critical care, 2001, Volume: 7, Issue:6 Topics: Energy Metabolism; Humans; Ischemia; Mitochondria; Mitochondrial Diseases; Multiple Organ Failure; NAD; Oxygen Consumption; Reperfusion Injury; Shock, Hemorrhagic; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha	2001

Other Studies

33 other study(ies) available for nad and Electron Transport Chain Deficiencies, Mitochondrial

Article	Year
The Gro3p factor: Restoring NAD+/NADH homeostasis to ameliorate mitochondrial disease. Cell metabolism, 2021, 10-05, Volume: 33, Issue:10 Topics: Animals; Cytosol; Homeostasis; Mice; Mitochondria; Mitochondrial Diseases; NAD	2021
NAD Clinical and translational medicine, 2021, Volume: 11, Issue:12 Topics: Gene Regulatory Networks; Humans; Mitochondrial Diseases; NAD; Obesity; Oocytes; Sirtuin 3	2021
OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway. eLife, 2022, 04-25, Volume: 11 Topics: Adenosine Triphosphate; Cell Proliferation; Genes, Fungal; Humans; Methanol; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Peroxisomes; Protein Serine-Threonine Kinases; Repressor Proteins; Saccharomycetales; Signal Transduction	2022
Restoring cellular NAD(P)H levels by PPARα and LXRα stimulation to improve mitochondrial complex I deficiency. Life sciences, 2022, Jul-01, Volume: 300 Topics: ATP Binding Cassette Transporter 1; Cholesterol; Electron Transport Complex I; HeLa Cells; Humans; Liver X Receptors; Mitochondrial Diseases; NAD; PPAR alpha	2022
Pyruvate and uridine rescue the metabolic profile of OXPHOS dysfunction. Molecular metabolism, 2022, Volume: 63 Topics: Animals; Metabolome; Mitochondrial Diseases; NAD; Oxidative Phosphorylation; Pyruvic Acid; Rotenone; Uridine; Zebrafish	2022
Early loss of endogenous NAD The FEBS journal, 2023, Volume: 290, Issue:6 Topics: Animals; Armadillo Domain Proteins; Drosophila melanogaster; Mitochondria; Mitochondrial Diseases; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Rotenone	2023
Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis. Journal of translational medicine, 2023, Dec-06, Volume: 21, Issue:1 Topics: Animals; Endothelial Cells; Inflammation; Mice; Mitochondrial Diseases; NAD; Nicotinamide Mononucleotide; Sepsis; Sirtuin 3	2023
Succinate dehydrogenase deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:1 Topics: Animals; Chromaffin Cells; Electron Transport Complex I; Humans; Male; Mice; Mice, Knockout; Mitochondria; Mitochondrial Diseases; Mutation; NAD; Neoplasms; Succinate Dehydrogenase; Transcriptome	2020
Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1-FOXO1/3-PINK1-Parkin-mediated mitophagy. Journal of sport and health science, 2021, Volume: 10, Issue:1 Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Brain-Derived Neurotrophic Factor; Disease Progression; Exercise; Forkhead Box Protein O1; Humans; Mitochondria; Mitochondrial Diseases; Mitophagy; NAD; Niacinamide; Nicotinamide Mononucleotide; Protein Kinases; Pyridinium Compounds; Reactive Oxygen Species; Sirtuin 1; Ubiquitin-Protein Ligases	2021
iPSC-derived neuronal models of PANK2-associated neurodegeneration reveal mitochondrial dysfunction contributing to early disease. PloS one, 2017, Volume: 12, Issue:9 Topics: Acetyl Coenzyme A; Adolescent; Biopsy; Brain; Cell Differentiation; Child; Coenzyme A; Female; Fibroblasts; Humans; Induced Pluripotent Stem Cells; Iron; Karyotyping; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Mutation; NAD; Neurons; Pantothenate Kinase-Associated Neurodegeneration; Pantothenic Acid; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Reactive Oxygen Species	2017
A specific amino acid formula prevents alcoholic liver disease in rodents. American journal of physiology. Gastrointestinal and liver physiology, 2018, 05-01, Volume: 314, Issue:5 Topics: Alcohol Drinking; Amino Acids, Branched-Chain; Animals; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Fatty Liver; Hep G2 Cells; Hepatocytes; Humans; Liver; Mitochondria; Mitochondrial Diseases; NAD; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species	2018
2,4 Dinitrophenol Attenuates Mitochondrial Dysfunction and Improves Neurobehavioral Outcomes Postanoxia in Neonatal Rats. Neurotoxicity research, 2018, Volume: 34, Issue:1 Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Animals, Newborn; bcl-2-Associated X Protein; Caspases; Cyclin D1; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypoxia; Membrane Potential, Mitochondrial; Mental Disorders; Mitochondrial Diseases; NAD; Oxidative Stress; Oxidoreductases; Pregnancy; Rats; Succinate Dehydrogenase	2018
Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock. JCI insight, 2018, 09-06, Volume: 3, Issue:17 Topics: Acidosis, Lactic; Adenosine Triphosphate; Animals; Cytokines; Hepatocytes; Humans; Inflammation; Interleukin-6; Kidney; Liver; Male; Mitochondria; Mitochondrial Diseases; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Nicotinamide-Nucleotide Adenylyltransferase; Rats; Resuscitation; Shock, Hemorrhagic; Survival Analysis	2018
Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD Cell death & disease, 2018, 11-14, Volume: 9, Issue:11 Topics: Adenosine Triphosphate; Aspartic Acid; Cell Death; Culture Media; Electron Transport Complex I; Fibroblasts; Galactose; Gene Expression; Glycolysis; Humans; Ketoglutaric Acids; Leigh Disease; Malates; Mitochondria; Mitochondrial Diseases; Mutation; NAD; NADH Dehydrogenase; Oxaloacetic Acid; Primary Cell Culture; Pyruvic Acid; Skin	2018
Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms. Neurotoxicity research, 2019, Volume: 35, Issue:3 Topics: Adenosine Triphosphate; Brain; Cell Survival; HEK293 Cells; Humans; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; NAD; Neurons; Oxidative Stress; Primary Cell Culture; Quinolinic Acid; Reactive Oxygen Species	2019
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell reports, 2019, 01-29, Volume: 26, Issue:5 Topics: Adipose Tissue; Animals; Ataxin-7; Blood Glucose; Energy Metabolism; Humans; Kynurenine; Metabolomics; Mice; Mitochondria; Mitochondrial Diseases; NAD; Neural Stem Cells; Organelles; Peptides; Phenotype; Purkinje Cells; Reproducibility of Results; Spinocerebellar Ataxias; Trinucleotide Repeat Expansion; Tryptophan	2019
A novel mutation in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:10 Topics: Calcium; Cell Cycle Proteins; Cell Line; Child; Electron Transport Complex I; Endosomes; Humans; Male; Mitochondria; Mitochondrial Diseases; Mutation; NAD; NADH Dehydrogenase; Neurodevelopmental Disorders; Pyruvates	2019
Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure. Cell metabolism, 2013, Aug-06, Volume: 18, Issue:2 Topics: Acetylation; Animals; Cardiotonic Agents; Dobutamine; Electron Transport Complex I; Female; Heart Failure; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitochondrial Diseases; Myocardium; NAD; Oxidative Stress; Pregnancy; Reactive Oxygen Species; Sirtuin 3	2013
Mitochondrial dysfunction and chronic disease: treatment with natural supplements. Alternative therapies in health and medicine, 2014,Winter, Volume: 20 Suppl 1 Topics: Carnitine; Dietary Supplements; Fatigue Syndrome, Chronic; Humans; Mitochondrial Diseases; NAD; Thioctic Acid; Ubiquinone	2014
NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease. Cell metabolism, 2014, Jun-03, Volume: 19, Issue:6 Topics: Animals; Dietary Supplements; Disease Models, Animal; Electron Transport Complex IV; Energy Metabolism; Enzyme Activation; Gene Expression; Mice; Mice, Knockout; Mitochondria; Mitochondrial Diseases; Molecular Chaperones; NAD; Niacinamide; Oxidative Phosphorylation; Phenanthrenes; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridinium Compounds; Sirtuin 1	2014
Mitochondrial complex I deficiency enhances skeletal myogenesis but impairs insulin signaling through SIRT1 inactivation. The Journal of biological chemistry, 2014, Jul-18, Volume: 289, Issue:29 Topics: Animals; Cell Line; Electron Transport Complex I; Gene Knockdown Techniques; Insulin; Insulin Resistance; Mice; Mitochondrial Diseases; Models, Biological; Muscle Development; Muscle Fibers, Skeletal; Muscle, Skeletal; NAD; Oxidative Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Small Interfering; Signal Transduction; Sirtuin 1	2014
Cerebral glucose hypometabolism is associated with mitochondrial dysfunction in patients with intractable epilepsy and cortical dysplasia. Epilepsia, 2014, Volume: 55, Issue:9 Topics: Adolescent; Cerebral Cortex; Child; Child, Preschool; Electroencephalography; Electron Transport Complex IV; Epilepsy; Female; Fluorodeoxyglucose F18; Glial Fibrillary Acidic Protein; Humans; Male; Malformations of Cortical Development; Mitochondrial Diseases; NAD; Positron-Emission Tomography; Proto-Oncogene Proteins c-akt; Retrospective Studies	2014
Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio. Science (New York, N.Y.), 2016, Apr-08, Volume: 352, Issue:6282 Topics: Catalysis; Cytosol; Electron Transport; Electron Transport Chain Complex Proteins; Genetic Complementation Test; Gluconeogenesis; HeLa Cells; Humans; Levilactobacillus brevis; Mitochondria; Mitochondrial Diseases; Multienzyme Complexes; NAD; NADH, NADPH Oxidoreductases; Oxidation-Reduction	2016
Three-Dimensional Model of Human Nicotinamide Nucleotide Transhydrogenase (NNT) and Sequence-Structure Analysis of its Disease-Causing Variations. Human mutation, 2016, Volume: 37, Issue:10 Topics: Amino Acid Sequence; Binding Sites; Genetic Predisposition to Disease; Humans; Mitochondrial Diseases; Mitochondrial Proteins; Models, Molecular; Mutation; NAD; NADP Transhydrogenase, AB-Specific; Protein Binding; Protein Conformation; Protein Domains	2016
NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Feb-24, Volume: 30, Issue:8 Topics: Animals; Apoptosis Inducing Factor; Cell Death; Cell Respiration; Cells, Cultured; Energy Metabolism; Glycolysis; Mice; Mice, Knockout; Mitochondria; Mitochondrial Diseases; NAD; Nerve Degeneration; Neurons; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Transport; Receptors, Purinergic P2; Receptors, Purinergic P2X7	2010
Focal cerebral ischemia and mitochondrial dysfunction in the TNFα-transgenic rat. Brain research, 2011, Apr-12, Volume: 1384 Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Blood Glucose; Brain Ischemia; Calcium; Cerebral Cortex; Electron Transport; Energy Metabolism; Mitochondria; Mitochondrial Diseases; NAD; Rats; Reactive Oxygen Species; Tumor Necrosis Factor-alpha	2011
Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway. Journal of Alzheimer's disease : JAD, 2011, Volume: 26, Issue:3 Topics: Adenine Nucleotides; Amyloid beta-Peptides; Antineoplastic Agents, Phytogenic; Autophagy; Blotting, Western; Caspases; Cell Line, Tumor; Cell Proliferation; Coloring Agents; Electron Transport Complex IV; Enzyme Activation; Humans; Lysosomes; Microscopy, Confocal; Microtubules; Mitochondrial Diseases; Mitochondrial Membranes; NAD; Paclitaxel; Peptide Fragments; Signal Transduction; Tetrazolium Salts; Thiazoles; Tubulin	2011
Exploring the therapeutic space around NAD+. The Journal of cell biology, 2012, Oct-15, Volume: 199, Issue:2 Topics: ADP-ribosyl Cyclase; Energy Metabolism; Humans; Metabolic Diseases; Mitochondria; Mitochondrial Diseases; NAD; Poly(ADP-ribose) Polymerases; Signal Transduction; Sirtuins	2012
POS5 gene of Saccharomyces cerevisiae encodes a mitochondrial NADH kinase required for stability of mitochondrial DNA. Eukaryotic cell, 2003, Volume: 2, Issue:4 Topics: Adenosine Triphosphate; Cells, Cultured; Copper; DNA, Mitochondrial; Energy Metabolism; Escherichia coli; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Mutation; NAD; Oxidative Stress; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Reactive Oxygen Species; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins	2003
HUMAN MYOPATHY WITH GIANT ABNORMAL MITOCHONDRIA. Science (New York, N.Y.), 1964, Jul-31, Volume: 145, Issue:3631 Topics: Acid Phosphatase; Adenosine Triphosphatases; Biopsy; Child; Electron Transport Complex IV; Electrons; Histocytochemistry; Humans; Lysosomes; Microscopy; Microscopy, Electron; Mitochondria; Mitochondrial Diseases; Muscles; Muscular Diseases; NAD; Oxidoreductases; Succinate Dehydrogenase	1964
Oxidation-reduction states of NADH in vivo: from animals to clinical use. Mitochondrion, 2007, Volume: 7, Issue:5 Topics: Animals; Blood Circulation; Gerbillinae; Humans; Male; Mitochondria; Mitochondrial Diseases; Monitoring, Physiologic; NAD; Oxidation-Reduction; Spectrometry, Fluorescence	2007
Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury. Journal of neurochemistry, 2008, Volume: 104, Issue:6 Topics: Animals; Brain; Brain Injuries; Cell Respiration; Electron Transport; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; NAD; Nitrogen; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley	2008
Hippocampal mitochondrial dysfunction in rat aging. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2 Topics: Aging; Animals; Electron Transport Complex I; Electron Transport Complex III; Electron Transport Complex IV; Energy Metabolism; Hippocampus; Male; Mitochondria; Mitochondrial Diseases; NAD; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances	2008