Page last updated: 2024-08-17

nad and Degenerative Diseases, Central Nervous System

nad has been researched along with Degenerative Diseases, Central Nervous System in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (17.46)	29.6817
2010's	26 (41.27)	24.3611
2020's	26 (41.27)	2.80

Authors

Authors	Studies
Cao, Y; Lin, X; Liu, F; Pan, M; Sun, G; Tan, X; Zhao, K; Zhao, Q; Zheng, L	1
Beura, S; Ghosh, R; Mishra, P; Modak, R	1
Braidy, N; Helman, T	1
Chen, X; Gao, M; Hu, C; Li, W; Zhou, Y	1
Bommireddipalli, S; Bournazos, AM; Christodoulou, J; Cooper, ST; Garza, D; Gooley, S; Gunanayagam, K; Jones, DL; Linster, CL; Lunke, S; McLean, CA; Naidoo, P; Patraskaki, M; Rajasekaran, M; Sebire, D; Semcesen, LN; Sikora, T; Stroud, DA; Van Bergen, NJ; Wallis, M; Walvekar, AS; Warmoes, MO	1
Duarte-Pereira, S; Matos, S; Oliveira, JL; Silva, RM	1
Borén, J; Doganay, HL; Jin, H; Li, X; Mardinoglu, A; Nielsen, J; Ozturk, G; Turkez, H; Uhlén, M; Yang, H; Zhang, C	1
Baur, JA; Bhasin, S; Migaud, M; Musi, N; Seals, D	1
Lu, HC; Park, JH; Yang, S	1
Green, M; Griffiths, JC; Ho, E; Huber, LG; Neufeld, LM; Obeid, R; Stout, M; Tzoulis, C	1
Fang, EF; Lautrup, S; Mattson, MP; Sinclair, DA	1
Fang, F; Gong, S; Li, J; Prokisch, H; Ren, X; Stenton, SL; Zhou, J	1
Braidy, N; Liu, Y	1
Castro-Portuguez, R; Sutphin, GL	1
Bressac, L; Guerreiro, S; Privat, AL; Toulorge, D	1
Chronister, WD; Fragola, G; Li, Z; Mabb, AM; Mao, H; McConnell, MJ; Niehaus, JK; Simon, JM; Taylor-Blake, B; Yuan, H; Zylka, MJ	1
Christodoulou, J; Linster, CL; Van Bergen, NJ	1
Abe, J; Borna, NN; Furukawa, T; Fushimi, T; Imai-Okazaki, A; Kishita, Y; Murayama, K; Ogawa-Tominaga, M; Ohtake, A; Okazaki, Y; Takeda, A	1
Berger, NA; Kincaid, JW	1
Jeong, H; Kim, KW; Lee, Y; Park, KH	1
Musiek, ES; Smith, SK	1
Gong, Z; Jiao, F	1
Gao, W; Huang, C; Huber, PE; Li, C; Shen, G; Xie, N; Zhang, L; Zhou, X; Zou, B	1
McCully, KS	1
Kratz, EM; Kubis-Kubiak, A; Piwowar, A; Sołkiewicz, K	1
Brazill, JM; Li, C; Zhai, RG; Zhu, Y	1
Osborne, B; Samsudeen, AF; Sultani, G; Turner, N	1
Hoek, JB; Rottenberg, H	1
Nakagawa, T; Okabe, K; Yaku, K	1
Ahting, U; Baple, E; Baptista, J; Becker-Kettern, J; Christodoulou, J; Conrotte, JF; Daubeney, P; Ellard, S; Ellaway, C; Girisha, KM; Guo, Y; Hakonarson, H; Homfray, T; Kay, DP; Kovacs-Nagy, R; Kremer, LS; Lewis, LES; Linster, CL; Massey, S; Montoya, J; Paczia, N; Power, R; Prelog, K; Pritsch, M; Procopis, P; Prokisch, H; Pyle, A; Rankin, J; Ruiz-Pesini, E; Santra, S; Shukla, A; Taylor, RW; Thorburn, DR; Van Bergen, NJ; Wakeling, M	1
Klimova, N; Kristian, T	1
Savitz, J	1
Beal, MF; Lloret, A	1
Hikosaka, K; Nakagawa, T; Okabe, K; Yaku, K	1
Guarente, L; Herskovits, AZ	1
Alleaume-Butaux, A; Brugg, B; Deleglise, B; Hjorth, JJ; Lassus, B; Peyrin, JM; Schneider, B; Soubeyre, V; Vignes, M; Viovy, JL	1
Di Stefano, G; Manerba, M; Vettraino, M	1
Sibon, OC; Srinivasan, B	1
Gray, JJ; Linseman, DA; Stankiewicz, TR; Winter, AN	1
Harrington, M	1
Fishman, PS; Kristian, T; Long, AN; Owens, K; Schlappal, AE; Schuh, RA	1
Auwerx, J; Cantó, C; Menzies, KJ	1
Verdin, E	1
Chang, B; Lu, S; Peng, J; Quan, Q; Wang, Y	1
Scheibye-Knudsen, M	1
Haigis, MC; Santos, D; van de Ven, RAH	1
Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D	1
Aljada, A; Dong, L; Mousa, SA	1
Balan, I; Kristian, T; Onken, M; Schuh, R	1
Chertov, AO; Couron, D; Holzhausen, L; Hurley, JB; Kuok, IT; Linton, JD; Parker, E; Sadilek, M; Sweet, IR	1
Braidy, N; Grant, R; Guillemin, GJ; Massudi, H	1
Fernandez, E; Goldstein, DS; Martinez, PA; Strong, R; Sullivan, P; Wey, MC	1
Giaume, C; Orellana, JA; Sáez, JC; von Bernhardi, R	1
Bedalov, A; Simon, JA	1
Buck, HM	1
Adam-Vizi, V; Tretter, L	1
Kennedy, BK; Longo, VD	1
Belenky, P; Bogan, KL; Brenner, C	1
Grant, RS; Jayasena, T; Keerthisinghe, N; Smythe, GA; Solaja, I	1
Forouhar, F; Khan, JA; Tao, X; Tong, L	1
Auwerx, J; Dali-Youcef, N; Froelich, S; Koehl, C; Lagouge, M; Schoonjans, K	1
Darlington, LG; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N	1
Ying, W	1

Reviews

43 review(s) available for nad and Degenerative Diseases, Central Nervous System

Article	Year
Importance of NAD+ Anabolism in Metabolic, Cardiovascular and Neurodegenerative Disorders. Drugs & aging, 2023, Volume: 40, Issue:1 Topics: Aging; Dietary Supplements; Humans; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide	2023
NMNAT2: An important metabolic enzyme affecting the disease progression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 158 Topics: Axons; Disease Progression; Humans; NAD; Neurodegenerative Diseases; Nicotinamide-Nucleotide Adenylyltransferase; Wallerian Degeneration	2023
Nicotinamide Adenine Dinucleotide in Aging Biology: Potential Applications and Many Unknowns. Endocrine reviews, 2023, 11-09, Volume: 44, Issue:6 Topics: Aged; Aging; Biology; Fatty Liver; Humans; NAD; Neurodegenerative Diseases	2023
Axonal energy metabolism, and the effects in aging and neurodegenerative diseases. Molecular neurodegeneration, 2023, 07-20, Volume: 18, Issue:1 Topics: Aging; Animals; Axons; Energy Metabolism; Glucose; Humans; NAD; Neurodegenerative Diseases	2023
NAD Cell metabolism, 2019, 10-01, Volume: 30, Issue:4 Topics: Aging; Animals; Brain; Cell Line; Humans; Mice; NAD; Neurodegenerative Diseases; Neurons; Rats	2019
NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Experimental gerontology, 2020, Volume: 132 Topics: Aging; Animals; Humans; Inflammation; Mice; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide; Oxidative Stress; Pyridinium Compounds; Rats; Risk Assessment	2020
Kynurenine pathway, NAD Experimental gerontology, 2020, Volume: 132 Topics: Aging; Animals; Brain; Humans; Kynurenine; Longevity; Metabolic Networks and Pathways; Mice; Mitochondria; Mitophagy; NAD; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Tryptophan	2020
CD38 in Neurodegeneration and Neuroinflammation. Cells, 2020, 02-18, Volume: 9, Issue:2 Topics: ADP-ribosyl Cyclase 1; Aging; Animals; Astrocytes; Brain; Humans; Membrane Glycoproteins; Mice; Mice, Knockout; Microglia; NAD; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents	2020
Effects of NAD Biomolecules, 2020, 07-02, Volume: 10, Issue:7 Topics: Animals; Caenorhabditis elegans; Disease Models, Animal; NAD; Nerve Regeneration; Neurodegenerative Diseases; Neuroprotection; Neurotoxins; Signal Transduction	2020
Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases. International review of neurobiology, 2020, Volume: 154 Topics: Chronobiology Disorders; Humans; Mitochondria; NAD; Neurodegenerative Diseases; Sirtuins; Sleep Wake Disorders	2020
The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases. Oxidative medicine and cellular longevity, 2020, Volume: 2020 Topics: Animals; Brain Injuries, Traumatic; Humans; NAD; Neurodegenerative Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Resveratrol; Sirtuin 1; Toll-Like Receptors	2020
NAD Signal transduction and targeted therapy, 2020, 10-07, Volume: 5, Issue:1 Topics: Aging; Cyclic ADP-Ribose; Humans; Metabolic Diseases; NAD; NADP; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction	2020
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging. Annals of clinical and laboratory science, 2020, Volume: 50, Issue:5 Topics: Aging; Animals; Arteriosclerosis; Cholesterol; Diterpenes; Homocysteine; Humans; Mitochondria; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Phosphorylation; Permeability; Squalene; Tocotrienols; Vitamin B 12	2020
Sirtuins as Important Factors in Pathological States and the Role of Their Molecular Activity Modulators. International journal of molecular sciences, 2021, Jan-10, Volume: 22, Issue:2 Topics: Gene Expression Regulation; Humans; NAD; Neoplasms; Neurodegenerative Diseases; Oxidative Stress; Sirtuins	2021
NMNAT: It's an NAD Current opinion in genetics & development, 2017, Volume: 44 Topics: Amide Synthases; Humans; Molecular Chaperones; NAD; Neurodegenerative Diseases; Neurons; Nicotinamide-Nucleotide Adenylyltransferase	2017
NAD Journal of neuroendocrinology, 2017, Volume: 29, Issue:10 Topics: Aging; Animals; Homeostasis; Humans; NAD; Neoplasms; Neurodegenerative Diseases	2017
The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore. Aging cell, 2017, Volume: 16, Issue:5 Topics: Aging; Animals; Calcium; Caloric Restriction; Cyclophilins; Gene Expression Regulation; Humans; Ischemic Preconditioning; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NAD; Neurodegenerative Diseases; Oxidation-Reduction; Reactive Oxygen Species; Reperfusion Injury	2017
NAD metabolism: Implications in aging and longevity. Ageing research reviews, 2018, Volume: 47 Topics: Aging; Animals; Humans; Longevity; NAD; Neoplasms; Neurodegenerative Diseases	2018
Multi-targeted Effect of Nicotinamide Mononucleotide on Brain Bioenergetic Metabolism. Neurochemical research, 2019, Volume: 44, Issue:10 Topics: Animals; Brain; Humans; Hydrolases; Mitochondria; NAD; Neurodegenerative Diseases; Niacinamide; Nicotinamide Mononucleotide	2019
The kynurenine pathway: a finger in every pie. Molecular psychiatry, 2020, Volume: 25, Issue:1 Topics: Aging; Animals; Energy Metabolism; Humans; Kynurenine; Mental Disorders; NAD; Neurodegenerative Diseases; Signal Transduction; Tryptophan	2020
PGC-1α, Sirtuins and PARPs in Huntington's Disease and Other Neurodegenerative Conditions: NAD+ to Rule Them All. Neurochemical research, 2019, Volume: 44, Issue:10 Topics: Animals; Humans; Mitochondria; NAD; Neurodegenerative Diseases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Poly (ADP-Ribose) Polymerase-1; Sirtuins	2019
Implications of NAD metabolism in pathophysiology and therapeutics for neurodegenerative diseases. Nutritional neuroscience, 2021, Volume: 24, Issue:5 Topics: Animals; Humans; Mitochondria; NAD; Neurodegenerative Diseases	2021
Sirtuin deacetylases in neurodegenerative diseases of aging. Cell research, 2013, Volume: 23, Issue:6 Topics: Aging; Caloric Restriction; Energy Metabolism; Histone Deacetylases; Humans; NAD; Neurodegenerative Diseases; Sirtuins	2013
NAD metabolism and functions: a common therapeutic target for neoplastic, metabolic and neurodegenerative diseases. Current topics in medicinal chemistry, 2013, Volume: 13, Issue:23 Topics: Humans; Metabolic Diseases; NAD; Neoplasms; Neurodegenerative Diseases	2013
Coenzyme A, more than 'just' a metabolic cofactor. Biochemical Society transactions, 2014, Volume: 42, Issue:4 Topics: Animals; Coenzyme A; Humans; NAD; Neurodegenerative Diseases; Phosphotransferases (Alcohol Group Acceptor)	2014
C-terminal binding proteins: central players in development and disease. Biomolecular concepts, 2014, Volume: 5, Issue:6 Topics: Alcohol Oxidoreductases; Animals; Apoptosis; Cell Survival; Co-Repressor Proteins; DNA-Binding Proteins; Growth and Development; Humans; NAD; Neoplasms; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Oxidation-Reduction; Protein Conformation; Protein Processing, Post-Translational; Transcriptional Activation	2014
NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus. Cell metabolism, 2015, Jul-07, Volume: 22, Issue:1 Topics: Aging; Animals; Cell Nucleus; Energy Metabolism; Homeostasis; Humans; Metabolic Diseases; Mitochondria; Molecular Targeted Therapy; NAD; Neoplasms; Neurodegenerative Diseases; Poly(ADP-ribose) Polymerases; Sirtuins	2015
NAD⁺ in aging, metabolism, and neurodegeneration. Science (New York, N.Y.), 2015, Dec-04, Volume: 350, Issue:6265 Topics: Aging; Biosynthetic Pathways; Diabetes Mellitus, Type 2; DNA Damage; Fatty Liver; Humans; Mitochondria; NAD; Neurodegenerative Diseases; Obesity; Oxidation-Reduction; Poly(ADP-ribose) Polymerases; Sirtuins	2015
Molecular mechanisms in the initiation phase of Wallerian degeneration. The European journal of neuroscience, 2016, Volume: 44, Issue:4 Topics: Animals; Axons; Humans; NAD; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Wallerian Degeneration	2016
Neurodegeneration in accelerated aging. Danish medical journal, 2016, Volume: 63, Issue:11 Topics: Aging, Premature; Animals; Ataxia Telangiectasia; Bloom Syndrome; Cockayne Syndrome; DNA Repair; Dyskeratosis Congenita; Fanconi Anemia; Humans; Mitochondria; Mitophagy; NAD; Neurodegenerative Diseases; Poly(ADP-ribose) Polymerases; Progeria; Rothmund-Thomson Syndrome; Sirtuin 1; Telomere Shortening; Werner Syndrome; Xeroderma Pigmentosum	2016
Mitochondrial Sirtuins and Molecular Mechanisms of Aging. Trends in molecular medicine, 2017, Volume: 23, Issue:4 Topics: Aging; Animals; Hearing Loss; Humans; Mitochondria; NAD; Neurodegenerative Diseases; Protein Interaction Maps; Sirtuins; Stress, Physiological	2017
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:11 Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan	2009
Sirtuin-targeting drugs: Mechanisms of action and potential therapeutic applications. Current opinion in investigational drugs (London, England : 2000), 2010, Volume: 11, Issue:10 Topics: Alzheimer Disease; Drug Delivery Systems; Group III Histone Deacetylases; Histone Deacetylases; Humans; Longevity; Metabolic Diseases; NAD; Neurodegenerative Diseases; Saccharomyces cerevisiae; Sirtuins	2010
Mitochondrial dysfunction and nicotinamide dinucleotide catabolism as mechanisms of cell death and promising targets for neuroprotection. Journal of neuroscience research, 2011, Volume: 89, Issue:12 Topics: ADP-ribosyl Cyclase 1; Animals; Cell Death; Humans; Metabolism; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NAD; Neurodegenerative Diseases; Neuroprotective Agents	2011
NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns. Redox report : communications in free radical research, 2012, Volume: 17, Issue:1 Topics: Aging; Animals; Cell Death; Cell Membrane; DNA Repair; Energy Metabolism; Enzyme Activation; Humans; Kynurenine; Mammals; NAD; Neurodegenerative Diseases; Oxidative Stress; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Sirtuins	2012
Glial hemichannels and their involvement in aging and neurodegenerative diseases. Reviews in the neurosciences, 2012, Jan-26, Volume: 23, Issue:2 Topics: Adenosine Triphosphate; Aging; Astrocytes; Calcium; Cannabinoids; Central Nervous System; Connexin 43; Connexins; Dinoprostone; Glucose; Glutamic Acid; Humans; Inflammation; Interleukin-1beta; Ion Channels; NAD; Nerve Degeneration; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Oligodendroglia; Signal Transduction; Tumor Necrosis Factor-alpha	2012
Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2005, Dec-29, Volume: 360, Issue:1464 Topics: Citric Acid Cycle; Humans; Ketoglutarate Dehydrogenase Complex; Mitochondria; NAD; Neurodegenerative Diseases; Oxidative Stress; Reactive Oxygen Species	2005
Sirtuins in aging and age-related disease. Cell, 2006, Jul-28, Volume: 126, Issue:2 Topics: ADP Ribose Transferases; Aging; Animals; Diabetes Mellitus; Eukaryotic Cells; Histone Deacetylases; Humans; Models, Biological; NAD; Neoplasms; Neurodegenerative Diseases; Sirtuins	2006
NAD+ metabolism in health and disease. Trends in biochemical sciences, 2007, Volume: 32, Issue:1 Topics: ADP Ribose Transferases; ADP-ribosyl Cyclase; Aging; Animals; Candida glabrata; Candidiasis; Humans; Lipids; NAD; Neurodegenerative Diseases; Niacinamide; Poly(ADP-ribose) Polymerases; Sirtuins	2007
Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert opinion on therapeutic targets, 2007, Volume: 11, Issue:5 Topics: Acrylamides; Adenosine Diphosphate Ribose; Aging; Animals; Antineoplastic Agents; Autoimmune Diseases; Clinical Trials, Phase II as Topic; Cyclic ADP-Ribose; DNA Damage; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Mice; NAD; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Piperidines; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sirtuins; Tryptophan	2007
Sirtuins: the 'magnificent seven', function, metabolism and longevity. Annals of medicine, 2007, Volume: 39, Issue:5 Topics: Animals; Caenorhabditis elegans; Caloric Restriction; Drosophila melanogaster; Energy Metabolism; Histone Deacetylases; Humans; Longevity; Mammals; NAD; Neurodegenerative Diseases; Saccharomyces cerevisiae; Sirtuins	2007
Tryptophan, adenosine, neurodegeneration and neuroprotection. Metabolic brain disease, 2007, Volume: 22, Issue:3-4 Topics: Adenosine; Animals; Hepatic Encephalopathy; Humans; Kynurenine; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Tryptophan	2007
NAD+ and NADH in neuronal death. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2007, Volume: 2, Issue:3 Topics: Animals; Cell Death; Humans; NAD; Neurodegenerative Diseases; Neurons	2007

Trials

1 trial(s) available for nad and Degenerative Diseases, Central Nervous System

Article	Year
The acute effect of different NAD Free radical biology & medicine, 2023, Aug-20, Volume: 205 Topics: Humans; Metabolic Diseases; NAD; Neurodegenerative Diseases; Niacin; Niacinamide; Nicotinamide Mononucleotide	2023

Other Studies

19 other study(ies) available for nad and Degenerative Diseases, Central Nervous System

Article	Year
Drug Value of Drynariae Rhizoma Root-Derived Extracellular Vesicles for Neurodegenerative Diseases Based on Proteomics and Bioinformatics. Plant signaling & behavior, 2022, 12-31, Volume: 17, Issue:1 Topics: Computational Biology; Extracellular Vesicles; Humans; NAD; Neurodegenerative Diseases; Oxidoreductases; Plant Roots; Polypodiaceae; Proteomics; Quinones	2022
Nutritional Epigenetics: How Metabolism Epigenetically Controls Cellular Physiology, Gene Expression and Disease. Sub-cellular biochemistry, 2022, Volume: 100 Topics: Chromatin; Epigenesis, Genetic; Gene Expression; Histones; Humans; Ketoglutaric Acids; NAD; Neurodegenerative Diseases	2022
Severe NAD(P)HX Dehydratase (NAXD) Neurometabolic Syndrome May Present in Adulthood after Mild Head Trauma. International journal of molecular sciences, 2023, Feb-10, Volume: 24, Issue:4 Topics: Adult; Brain Concussion; Brain Diseases, Metabolic; Child; Child, Preschool; Humans; Hydro-Lyases; Mitochondria; NAD; Neurodegenerative Diseases; Proteomics	2023
Study of NAD-interacting proteins highlights the extent of NAD regulatory roles in the cell and its potential as a therapeutic target. Journal of integrative bioinformatics, 2023, Jun-01, Volume: 20, Issue:2 Topics: Humans; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Signal Transduction	2023
Advancing nutrition science to meet evolving global health needs. European journal of nutrition, 2023, Volume: 62, Issue:Suppl 1 Topics: Child; Choline; Chronic Disease; Dietary Supplements; Global Health; Humans; Infant; NAD; Neurodegenerative Diseases; Nutritional Sciences; Xanthophylls	2023
NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses. Brain : a journal of neurology, 2020, 02-01, Volume: 143, Issue:2 Topics: Humans; Hydro-Lyases; NAD; Neurodegenerative Diseases	2020
Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration. Nature communications, 2020, 04-23, Volume: 11, Issue:1 Topics: Animals; Apoptosis; Cerebral Cortex; DNA Damage; DNA Topoisomerases, Type I; Genomic Instability; Hippocampus; Inflammation; Mice; Mice, Knockout; Mortality, Premature; Motor Activity; Mutation; NAD; Neurodegenerative Diseases; Neurons; Niacinamide; Poly (ADP-Ribose) Polymerase-1; Pyridinium Compounds	2020
Reply: NAD(P)HX dehydratase protein-truncating mutations are associated with neurodevelopmental disorder exacerbated by acute illness. Brain : a journal of neurology, 2020, 07-01, Volume: 143, Issue:7 Topics: Acute Disease; Humans; Hydro-Lyases; Mutation; NAD; Neurodegenerative Diseases; Neurodevelopmental Disorders	2020
NAD(P)HX dehydratase protein-truncating mutations are associated with neurodevelopmental disorder exacerbated by acute illness. Brain : a journal of neurology, 2020, 07-01, Volume: 143, Issue:7 Topics: Acute Disease; Humans; Hydro-Lyases; Mutation; NAD; Neurodegenerative Diseases; Neurodevelopmental Disorders	2020
NAD metabolism in aging and cancer. Experimental biology and medicine (Maywood, N.J.), 2020, Volume: 245, Issue:17 Topics: Aging; Animals; Humans; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Poly Adenosine Diphosphate Ribose	2020
NAD(P)HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses. Brain : a journal of neurology, 2019, 01-01, Volume: 142, Issue:1 Topics: Child, Preschool; Computer Simulation; Female; Fever; Fibroblasts; Genetic Vectors; Humans; Hydro-Lyases; Infant; Kinetics; Lentivirus; Male; Mitochondria; Mutation; NAD; Neurodegenerative Diseases; Primary Cell Culture; Whole Genome Sequencing	2019
Synapto-protective drugs evaluation in reconstructed neuronal network. PloS one, 2013, Volume: 8, Issue:8 Topics: Amides; Amino Acid Chloromethyl Ketones; Animals; Axons; Dendrites; Embryo, Mammalian; Enzyme Inhibitors; Mice; Microfluidics; Microscopy, Fluorescence; Models, Neurological; NAD; Nerve Net; Neurodegenerative Diseases; Primary Cell Culture; Pyridines; Resveratrol; Stilbenes; Synapses	2013
Reversing neurodegenerative hearing loss. Lab animal, 2015, Volume: 44, Issue:1 Topics: Animals; Disease Models, Animal; Hearing Loss; Humans; Mice; Mice, Knockout; NAD; Neurodegenerative Diseases; Niacinamide; Pyridinium Compounds; Sirtuin 3	2015
Effect of nicotinamide mononucleotide on brain mitochondrial respiratory deficits in an Alzheimer's disease-relevant murine model. BMC neurology, 2015, Mar-01, Volume: 15 Topics: Alzheimer Disease; Animals; Brain; Female; Male; Mice; Mice, Transgenic; Mitochondria; NAD; Neurodegenerative Diseases; Nicotinamide Mononucleotide; Oxygen Consumption	2015
Roles of glucose in photoreceptor survival. The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40 Topics: Acetylglucosamine; Adenosine Triphosphate; Animals; Autophagy; Cell Death; Cell Survival; Gas Chromatography-Mass Spectrometry; Glucose; Lactic Acid; Mice; Mice, Inbred C57BL; Mitochondria; NAD; Neurodegenerative Diseases; Neurons; Oxygen Consumption; Photoreceptor Cells, Vertebrate; Retina	2011
Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease. PloS one, 2012, Volume: 7, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehyde Dehydrogenase; Animals; Body Weight; Cognition Disorders; Cytosol; Disease Models, Animal; Dopamine; Female; Genotype; Male; Mice; Mice, Transgenic; Mitochondria; NAD; Neurodegenerative Diseases; Neurons; Parkinson Disease; Time Factors; Tyrosine 3-Monooxygenase	2012
Neuroscience. NAD to the rescue. Science (New York, N.Y.), 2004, Aug-13, Volume: 305, Issue:5686 Topics: Animals; Axons; Cell Nucleus; Cell Survival; Cells, Cultured; Ganglia, Spinal; Mice; Mutation; NAD; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; RNA, Small Interfering; Sirtuin 1; Sirtuins; Ubiquitin-Protein Ligases; Wallerian Degeneration	2004
The role of the carboxamide group in nicotinamide adenine dinucleotide in relation to hydride transfer: the reduced form of the dinucleotide as remedy in the modulation of neurotransmission. Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7 Topics: Adenine Nucleotides; Amides; Animals; Carbon; Dinucleoside Phosphates; Humans; Hydrogen; Kinetics; Molecular Conformation; NAD; Neurodegenerative Diseases; Neurons; Nitrogen; Nucleotides; Protein Folding; Stereoisomerism; Synaptic Transmission	2005
Membrane permeability of redox active metal chelators: an important element in reducing hydroxyl radical induced NAD+ depletion in neuronal cells. Neuroscience research, 2007, Volume: 57, Issue:3 Topics: Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Cytoplasm; Humans; Hydroxyl Radical; Intracellular Fluid; Iron Chelating Agents; Membrane Lipids; NAD; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress	2007