Page last updated: 2024-08-17

nad and Cancer of Pancreas

nad has been researched along with Cancer of Pancreas in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's2 (7.41)18.2507
2000's3 (11.11)29.6817
2010's8 (29.63)24.3611
2020's7 (25.93)2.80

Authors

AuthorsStudies
Dai, L; Kyani, A; Neamati, N; Roy, J; Sun, D; Xu, Y; Xue, D1
Chen, Q; Gong, J; He, X; Li, Y; Lin, C; Lou, J; Wu, Y; Zheng, L; Zhu, Y1
Cowan, A; Davidson, S; Downes, M; Evans, R; Guo, JY; Han, H; Lan, T; Liang, G; Lu, W; McBride, M; Ng, S; Nofal, M; Oh, TG; Rabinowitz, JD; TeSlaa, T; Von Hoff, D; Wang, L; Yang, L; Zeng, X1
Ackenhusen, SE; Andren, A; Chen, B; Crawford, HC; Galban, S; Gao, X; Halbrook, CJ; Hoffman, MT; Jiménez, JA; Kemp, SB; Kerk, SA; Lin, L; Lombard, DB; Long, D; Lyssiotis, CA; Myers, AL; Nelson, BS; Nwosu, ZC; Pasca di Magliano, M; Piwnica-Worms, DR; Ramos, J; Robinson, A; Sajjakulnukit, P; Shah, YM; Steele, NG; Sutton, DJ; Thurston, G; Wen, HJ; Ying, H; Zhang, L; Zhang, Y1
Chacko, JV; Desa, DE; Eliceiri, KW; Huisken, J; Huttenlocher, A; Li, J; Lin, W; Miskolci, V; Rogers, JD; Samimi, K; Skala, MC; Velten, A; Weiss, K1
Chougoni, KK; Dcona, DT; Dcona, MM; Ellis, KC; Grossman, SR; Singh, SJ; West, JL1
Abt, ER; Cui, J; Dann, AM; Dawson, DW; Donahue, TR; Elliott, I; Ghukasyan, R; Khachatourian, N; Kim, S; Le, T; Li, L; Liang, K; Moore, AM; Pagano, K; Poddar, S; Radu, CG; Riahi, R; Wu, N; Yu, A; Zhou, L1
Beg, MS; Hosein, AN1
Barbosa, MT; Camacho-Pereira, J; Chini, CC; Chini, EN; Escande, C; Guerrico, AM; Nin, V1
Cantley, LC; Lyssiotis, CA1
Guan, KL; Lin, H; Ling, ZQ; Shi, Q; Xiong, Y; Yang, H; Yang, Y; Ye, D; Zhang, M; Zhao, S; Zhao, Y; Zhou, L1
Chiao, PJ; Fan, XQ; Ju, HQ; Li, H; Lu, YX; Mo, HY; Sheng, H; Tian, T; Xu, RH; Zhou, HJ; Zhuang, ZN1
Isono, Y; Kawanishi, S; Kobayashi, H; Oikawa, S; Tada-Oikawa, S1
Gray, JP; Heart, E; Palo, M; Smith, PJ; Womack, T1
Ballestrero, A; Basile, G; Bauer, I; Bruzzone, S; Caffa, I; Cea, M; Feldmann, G; Grozio, A; Lasigliè, D; Magnone, M; Mostoslavsky, R; Nencioni, A; Patrone, F; Poggi, A; Sociali, G; Soncini, D; Sturla, L; Zoppoli, G1
Cai, AL; Li, L; Sheline, CT; Sheline, PJ; Shi, C; Takata, T; Zhang, W; Zhu, J1
Chang, I; Cho, N; Koh, JY; Lee, MS1
MIYAJI, T; MORI, M; MURAKAMI, M; MURATA, I1
Ashford, ML; Hales, CN; Reale, V1
Chen, SC; Kolar, C; Lawson, TA; Mirvish, SS; Wang, X; Zhou, L1
Doi, K1
Cormont, M; Le Marchand-Brustel, Y; Sharp, GW; Spiegel, AM; Van Obberghen, E1
Blachier, F; Malaisse, WJ; Sener, A1
Okamoto, H1
Giroix, MH; Hellerström, C; Leclercq-Meyer, V; Malaisse, WJ; Sener, A1
Dietz, AA; Lubrano, T; Rubinstein, HM1
Rudas, B1

Reviews

2 review(s) available for nad and Cancer of Pancreas

ArticleYear
Pancreatic Cancer Metabolism: Molecular Mechanisms and Clinical Applications.
    Current oncology reports, 2018, 05-11, Volume: 20, Issue:7

    Topics: Acrylamides; Adenocarcinoma; Antineoplastic Agents; Citric Acid Cycle; Glutaminase; Glutamine; Humans; Mitochondria; Molecular Targeted Therapy; NAD; NAD(P)H Dehydrogenase (Quinone); Pancreatic Neoplasms; Piperidines

2018
[Streptozotocin].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:5

    Topics: Adenoma, Islet Cell; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Diabetes Mellitus; Drug Resistance, Microbial; Humans; In Vitro Techniques; Islets of Langerhans; Microbial Sensitivity Tests; NAD; Nicotinic Acids; Nitroso Compounds; Pancreas; Pancreatic Neoplasms; Rats; Streptozocin; Urea

1972

Other Studies

25 other study(ies) available for nad and Cancer of Pancreas

ArticleYear
Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer.
    Journal of medicinal chemistry, 2022, 02-24, Volume: 65, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred C57BL; NAD; Oxidative Phosphorylation; Pancreatic Neoplasms; Sulfonamides; Xenograft Model Antitumor Assays

2022
O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction.
    Cell death and differentiation, 2022, Volume: 29, Issue:10

    Topics: Autoantigens; Carcinoma, Pancreatic Ductal; Cell Proliferation; Humans; N-Acetylglucosaminyltransferases; NAD; Pancreatic Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Serine; Sirtuins

2022
Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth.
    Med (New York, N.Y.), 2022, 02-11, Volume: 3, Issue:2

    Topics: Animals; Carbohydrates; Diet, Ketogenic; Humans; Mice; NAD; Pancreatic Neoplasms; Randomized Controlled Trials as Topic

2022
Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context.
    eLife, 2022, 07-11, Volume: 11

    Topics: Animals; Aspartate Aminotransferase, Mitochondrial; Carcinoma, Pancreatic Ductal; Fatty Acid-Binding Proteins; Humans; Mice; NAD; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Pyruvic Acid; Tumor Microenvironment

2022
Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array.
    Journal of biomedical optics, 2023, Volume: 28, Issue:6

    Topics: Animals; Microscopy, Fluorescence; NAD; Optical Imaging; Pancreatic Neoplasms; Photons; Zebrafish

2023
Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer.
    Cancer research communications, 2023, 10-04, Volume: 3, Issue:10

    Topics: Animals; DNA-Binding Proteins; Humans; Mice; NAD; Pancreatic Neoplasms; Transcription Factors

2023
NAD
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 02-23, Volume: 118, Issue:8

    Topics: Animals; Apoptosis; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Proliferation; Cytokines; Gene Expression Regulation, Neoplastic; Humans; Interferon Type I; Male; Mice; Mice, Inbred NOD; Mice, SCID; NAD; Neoplasm Proteins; Nicotinamide Phosphoribosyltransferase; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2021
Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jan-01, Volume: 20, Issue:1

    Topics: Acrylamides; ADP-ribosyl Cyclase 1; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytokines; Female; Humans; Membrane Glycoproteins; Mice; Mice, Nude; Molecular Targeted Therapy; NAD; Nicotinamide Phosphoribosyltransferase; Pancreatic Neoplasms; Piperidines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Sirtuin 1; Tumor Burden; Xenograft Model Antitumor Assays

2014
Targeting metabolic scavenging in pancreatic cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jan-01, Volume: 20, Issue:1

    Topics: Acrylamides; Animals; Antineoplastic Agents; Female; Humans; NAD; Pancreatic Neoplasms; Piperidines

2014
SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth.
    The EMBO journal, 2015, Apr-15, Volume: 34, Issue:8

    Topics: Acetylation; Animals; Aspartate Aminotransferase, Mitochondrial; Aspartic Acid; Biological Transport; Carcinoma, Pancreatic Ductal; Cell Proliferation; Cells, Cultured; HEK293 Cells; Humans; Malates; Male; Mice; Mice, Inbred C57BL; Mice, Nude; NAD; Oxidation-Reduction; Pancreatic Neoplasms; Protein Processing, Post-Translational; Sirtuin 3

2015
Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer.
    Cancer letters, 2016, 08-28, Volume: 379, Issue:1

    Topics: 3' Untranslated Regions; Acrylamides; Animals; Antimetabolites, Antineoplastic; Binding Sites; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cytokines; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gemcitabine; Glycolysis; Humans; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; MicroRNAs; NAD; Nicotinamide Phosphoribosyltransferase; Pancreatic Neoplasms; Piperidines; RNA Interference; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2016
Damage to cellular and isolated DNA induced by a metabolite of aspirin.
    Mutation research, 2009, Feb-10, Volume: 661, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aspirin; Cell Line, Tumor; Comet Assay; Copper; Deoxyguanosine; DNA Breaks, Single-Stranded; DNA Damage; DNA, Neoplasm; Genes, Tumor Suppressor; HL-60 Cells; Humans; Hydroxybenzoates; Hypoxanthine Phosphoribosyltransferase; In Vitro Techniques; Models, Biological; NAD; Pancreatic Neoplasms; Reactive Oxygen Species

2009
The level of menadione redox-cycling in pancreatic β-cells is proportional to the glucose concentration: role of NADH and consequences for insulin secretion.
    Toxicology and applied pharmacology, 2012, Jan-15, Volume: 258, Issue:2

    Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Glucose; Hydrogen Peroxide; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Islets of Langerhans; Male; Mice; NAD; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pancreatic Neoplasms; Rats; Reactive Oxygen Species; Vitamin K 3

2012
The NAD+-dependent histone deacetylase SIRT6 promotes cytokine production and migration in pancreatic cancer cells by regulating Ca2+ responses.
    The Journal of biological chemistry, 2012, Nov-30, Volume: 287, Issue:49

    Topics: Animals; Calcium; Cell Line, Tumor; Cell Movement; Cytokines; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Inflammation; Interleukin-8; Mice; NAD; NF-kappa B; Pancreatic Neoplasms; Retroviridae; RNA, Small Interfering; Signal Transduction; Sirtuins; Tumor Necrosis Factor-alpha

2012
Dietary zinc reduction, pyruvate supplementation, or zinc transporter 5 knockout attenuates β-cell death in nonobese diabetic mice, islets, and insulinoma cells.
    The Journal of nutrition, 2012, Volume: 142, Issue:12

    Topics: Animals; Benzamides; Calcium Channel Blockers; Carrier Proteins; Cell Line, Tumor; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Insulinoma; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; NAD; Naphthols; Pancreatic Neoplasms; Pyruvic Acid; Reactive Oxygen Species; Streptozocin; Zinc

2012
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes.
    Diabetologia, 2003, Volume: 46, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antigens, Polyomavirus Transforming; Antioxidants; Cell Death; Cell Line, Tumor; Cell Transformation, Neoplastic; Diabetes Mellitus, Experimental; Etoposide; Insulinoma; Interferon-gamma; Islets of Langerhans; NAD; Necrosis; Pancreatic Neoplasms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Staurosporine; Tumor Necrosis Factor-alpha; Zinc

2003
HISTOCHEMICAL OBSERVATIONS OF ALPHA-GLYCEROPHOS- PHATE DEHYDROGENASE ACTIVITY IN HUMAN TUMORS.
    Cancer research, 1963, Volume: 23

    Topics: Ameloblastoma; Breast Neoplasms; Female; Histocytochemistry; Humans; Metabolism; Mouth Neoplasms; NAD; Neoplasms; Oxidoreductases; Pancreatic Neoplasms; Pathology; Rectal Neoplasms; Research; Salivary Gland Neoplasms; Stomach Neoplasms; Thyroid Neoplasms; Uterine Cervical Neoplasms

1963
The effects of pyridine nucleotides on the activity of a calcium-activated nonselective cation channel in the rat insulinoma cell line, CRI-G1.
    The Journal of membrane biology, 1994, Volume: 142, Issue:3

    Topics: Animals; Calcium; Insulinoma; Ion Channels; Islets of Langerhans; Kinetics; Membrane Potentials; NAD; NADP; Pancreatic Neoplasms; Patch-Clamp Techniques; Rats; Tumor Cells, Cultured

1994
Metabolism of the hamster pancreatic carcinogen methyl-2-oxopropylnitrosamine by hamster liver and pancreas.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 2000, Volume: 27, Issue:2

    Topics: Animals; Carcinogens; Cricetinae; Cytosol; In Vitro Techniques; Liver; Male; Mesocricetus; Microsomes, Liver; NAD; NADP; Nitrosamines; Pancreas; Pancreatic Neoplasms; Rats; Rats, Sprague-Dawley

2000
[Studies on the mechanism of the diabetogenic activity of streptozotocin and on the ability of compounds to block the diabetogenic activity of streptozotocin (author's transl)].
    Nihon Naibunpi Gakkai zasshi, 1975, Mar-20, Volume: 51, Issue:3

    Topics: Adenoma, Islet Cell; Amides; Animals; Blood Glucose; Cats; Cystine; Deoxyglucose; Diabetes Mellitus; Dimethylnitrosamine; Fatty Acids, Nonesterified; Glutathione; Guinea Pigs; Insulin; Islets of Langerhans; Male; Mannoheptulose; Mice; NAD; Niacinamide; Nicotinic Acids; Pancreatic Neoplasms; Picolinic Acids; Pyrazinamide; Rabbits; Rats; Streptozocin; Tolbutamide; Uric Acid

1975
Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor.
    Diabetes, 1991, Volume: 40, Issue:9

    Topics: Amino Acid Sequence; Animals; Antibodies; Brain; Cell Line; Cell Membrane; Galanin; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Immunoassay; Insulinoma; Kidney; Macromolecular Substances; Molecular Sequence Data; NAD; Pancreatic Neoplasms; Peptides; Pertussis Toxin; Rats; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Virulence Factors, Bordetella

1991
Crabtree effect in tumoral pancreatic islet cells.
    The Journal of biological chemistry, 1988, Feb-05, Volume: 263, Issue:4

    Topics: Adenine Nucleotides; Adenoma, Islet Cell; Animals; Glucose; Glutamine; Lactates; Lactic Acid; Lipids; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Palmitic Acid; Palmitic Acids; Pancreatic Neoplasms; Tumor Cells, Cultured

1988
Degeneration, oncogenesis and regeneration of pancreatic beta-cells of islets of Langerhans.
    Nihon Naibunpi Gakkai zasshi, 1988, Dec-20, Volume: 64, Issue:12

    Topics: Adenoma, Islet Cell; Animals; Diabetes Mellitus, Type 1; DNA; DNA Damage; Gene Expression Regulation; Insulinoma; Islets of Langerhans; NAD; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerases; Regeneration

1988
Opposite effects of D-glucose and a nonmetabolized analogue of L-leucine on respiration and secretion in insulin-producing tumoral cells (RINm5F).
    Diabetes, 1987, Volume: 36, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Amino Acids, Cyclic; Animals; Cell Line; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; NAD; Oxygen Consumption; Pancreatic Neoplasms

1987
Extra lactate dehydrogenase isoenzyme band in serum of patients with severe liver disease.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Acute Disease; Alcoholism; Bilirubin; Carcinoma; Cholestasis; Electrophoresis, Disc; Fatty Liver; Follow-Up Studies; Hepatitis; Humans; Isoenzymes; L-Lactate Dehydrogenase; Liver Cirrhosis; Liver Diseases; NAD; Necrosis; Neoplasm Metastasis; Pancreatic Neoplasms; Stomach Neoplasms

1971