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Page last updated: 2024-08-17

nad and Alloxan Diabetes

nad has been researched along with Alloxan Diabetes in 133 studies

Research

Studies (133)

TimeframeStudies, this research(%)All Research%
pre-199074 (55.64)18.7374
1990's16 (12.03)18.2507
2000's21 (15.79)29.6817
2010's11 (8.27)24.3611
2020's11 (8.27)2.80

Authors

AuthorsStudies
Ahmad, R; Bari, DG; Gaur, R; Gautam, GK; Parveen, K; Rais, N; Shukla, KS; Singh, AP; Ved, A1
Corremans, R; D'Haese, PC; Verhulst, A; Vervaet, BA1
Beegum, F; Begum, F; George, KT; K P, D; Krishnadas, N; P V, A; Shenoy, RR1
Aguayo-Mazzucato, C; Bons, J; Butera, K; Hu, KQ; Kuehnemann, C; Patel, SK; Schilling, B; Wiley, CD1
Bogomolova, A; Ermakova, P; Kashina, A; Kashirina, A; Kornilova, I; Kuchin, D; Lugovaya, L; Myalik, D; Naraliev, N; Zagainov, V; Zagaynova, E1
Bragin, DE; Bragina, OA; Kameneva, MV; Monickaraj, F; Nemoto, EM; Noghero, A; Trofimov, AO1
Eprintsev, AT; Selivanova, NV1
Albanese, C; Bansal, S; Brodsky, L; Cheema, A; Ginley, B; Guha, U; Hirschey, MD; Jang, Y; Jones, BA; Kopp, JB; Krawczyk, E; Levi, M; Ma, J; Myakala, K; Na, CH; Panov, J; Qi, Y; Rosenberg, AZ; Sarder, P; Shults, NV; Wang, XX; Wu, C; Yang, X; Yoshida, T; Zhang, X1
Alonso, N; Camacho, M; Del Olmo, TV; Diarte-Añazco, EMG; Julián, MT; Julve, J; Martinez-Santos, P; Mauricio, D; Méndez-Lara, KA; Muñoz, JP; Niño-Narvión, J; Rossell, J; Rotllan, N; Torres-Méndez, JK1
Choi, YS; Kim, CH; Kim, E; Lee, JE; Song, HT; Song, JE1
Deng, KY; Ding, Q; Guan, XH; Li, Q; Wang, LF; Wen, K; Xiao, YF; Xin, HB; Zhang, YT; Zhao, JL; Zhao, QH1
Admed, B; Ansah, TA; Lai, CQ; LeRoith, T; Li, J; Liu, D; Ordovás, JM; Parnell, LD; Si, H; Wang, X; Zhang, L1
Ashcroft, FM; Baba, O; Blacker, TS; Brereton, MF; Davis, S; Duchen, MR; Fischer, R; Haythorne, E; MacRae, JI; Rohm, M; Rorsman, P; Sachse, G; Silva Dos Santos, M; Tarasov, AI; Terron Exposito, R; van de Bunt, M1
Benito-Martin, A; Carrasco, S; Egido, J; Izquierdo, MC; Lorenzo, O; Ortiz, A; Picatoste, B; Ruiz-Ortega, M; Santamaria, B; Ucero, AC1
Choi, JM; Kim, L; Lee, WY; Oh, KW; Park, CY; Park, SE; Park, SW; Rhee, EJ; Yang, SJ1
Datusalia, AK; Jangra, A; Sharma, SS1
Borges, CM; Lopes de Faria, JB; Lopes de Faria, JM; Papadimitriou, A; Peixoto, EB; Silva, KC1
Banke, NH; Lewandowski, ED1
De Feo, V; Dewanjee, S; Gangopadhyay, M; K Dua, T; Khanra, R; Sahu, R; Zia-Ul-Haq, M1
Berlovskaya, E; Cherkasova, O; Fadeev, V; Priezzhev, A; Shirshin, E; Tikhonova, T1
Chang, K; Ido, Y; Kilo, C; Mylari, BL; Nyengaard, JR; Oates, PJ; Tilton, RG; Williamson, JR1
Cai, AL; Li, L; Sheline, CT; Sheline, PJ; Shi, C; Takata, T; Zhang, W; Zhu, J1
Cerasi, E; Henquin, JC; Jonas, JC; Kaiser, N; Nesher, R; Pertusa, JA1
Angielski, S; Jankowski, M; Pawełczyk, T; Rudzik, A; Stiepanow-Trzeciak, A; Szczepańska-Konkel, M1
Chang, I; Cho, N; Koh, JY; Lee, MS1
GRAYMORE, CN; GREENBAUM, AL1
OJI, N1
GORDON, EE1
SIPPEL, TO1
MILSTEIN, SW; SPIRTES, MA1
ASHMORE, J; WAGLE, SR1
LAZAROW, A; LINDALL, AW1
HAUGAARD, ES; HAUGAARD, N1
BERTELS, H; HOHORST, HJ; STRATMANN, D1
BENJAMIN, W; GELLHORN, A1
KURIMOTO, S; NEWELL, FW1
LOEFFLER, G; WIELAND, O1
HAYAISHI, O; ICHIYAMA, A; IKEDA, M; NAKAMURA, S; NISHIZUKA, Y; TSUJI, H1
CLARK, JB; GREENBAUM, AL1
METZGER, RP; WICK, AN; WILCOX, SS1
Jeong, HY; Kim, CD1
Okamoto, H3
Abatan, OI; Charniauskaya, T; Li, F; Obrosova, IG; Pacher, P; Southan, GJ; Stevens, MJ; Szabó, C1
Dudzinska, W; Hlynczak, AJ1
Descatoire, V; Fromenty, B; Grandperret, T; Pessayre, D; Robin, MA; Sauvage, I1
Berkowitz, BA; Diederen, RM; Starnes, CA; Winkler, BS1
Liao, SD; Puro, DG1
Achike, FI; Ajay, M; Mustafa, MR1
Hisano, N1
Kaundal, RK; Kumar, A; Sharma, SS1
Assimacopoulos-Jeannet, F; Bas, S; Chinet, A; Giacobino, JP; Girardier, L; Imesch, E; Schneider-Picard, G; Seydoux, J1
Falany, J; Fischer, LJ; Fisher, R1
Andersson, A; Sandler, S; Welsh, M1
Okamoto, H; Yamamoto, H2
Valant, PA1
Assimacopoulos-Jeannet, F; Bas, S; Bouillaud, F; Giacobino, JP; Girardier, L; Ricquier, D; Seydoux, J; Trimble, ER1
Giacomelli, F; Kuo, TH; Moore, KH; Wiener, J1
Okamoto, H; Uchigata, Y; Yamamoto, H1
Ozawa, K; Sato, M; Tanaka, J; Tobe, T1
Tischler, ME1
Chitra, CI; Cuezva, JM; Patel, MS1
Hashimoto, Y; Maeda, S; Sano, K; Shin, M; Umezawa, C1
Cho, CG; Chung, HT; Kim, HR; Kim, JS; Park, BH; Park, JW; Rho, HW1
Laing, RA; Shimazaki, J; Tornheim, K; Tsubota, K; Yoshida, A1
Grunewald, RW; Kinne, RK; Kinne-Saffran, E; Weber, II1
Allison, W; Chang, K; Kilo, C; Williamson, JR1
Ido, Y; Kilo, C; Williamson, JR1
Bazotte, RB; Brunaldi, K; Ferraz, M; Oliveira, CE1
Di Giulio, AM; Donadoni, ML; Finco, C; Gorio, A1
Coffe, V; Hernández-Muñoz, R; Salceda, R; Vilchis, C1
Cao, X; Greene, DA; Obrosova, I; Stevens, MJ1
Allan, DJ; Cameron, DP; Cardinal, JW1
Jishage, K; Kamada, N; Masutani, M; Nakagama, H; Nozaki, T; Ochiya, T; Sugimoto, T; Sugimura, T; Suzuki, H; Ueda, O; Watanabe, M; Watanabe, T1
Fathallah, L; Greene, DA; Lang, HJ; Obrosova, IG1
Aotsuka, T; Ashizawa, N; Yoshida, M1
Cao, X; Fathallah, L; Greene, DA; Obrosova, IG; Stevens, MJ; Van Huysen, C1
Fathallah, L; Obrosova, IG1
Lang, HJ; Obrosova, IG; Stevens, MJ1
Andersson, AK; Sandler, S1
Akimoto, LS; Bazotte, RB; Lopes, G; Pedrinho, SR1
Cao, XC; Fathallah, L; Greene, DA; Obrosova, IG; Stevens, MJ; Van Huysen, C1
Abdelkarim, GE; Getting, SJ; Haskó, G; Jagtap, P; Liaudet, L; Mabley, JG; Marton, A; Perretti, M; Salzman, AL; Soriano, FG; Southan, GJ; Szabó, C; Szabó, E; Virág, L1
Harris, RA; Mapes, JP1
Arieff, AI; Kerian, A1
Dagaeva, LN1
Touster, O; Tulsiani, DR1
Feraudi, M1
Cooper, RH; Denton, RM; Kerbey, AL; Pask, HT; Randle, PJ; Whitehouse, S1
Glynn, D; Rossini, A; Wick, MM1
Carmena, MJ; Clemente, C; Guijarro, LG; Prieto, JC1
Green, A; Johnson, JL1
Gibson, RG; Goodwin, GW; Harris, RA; Paxton, R; Rougraff, PM1
Kawada, J; Nabeshima, A; Naito, S; Nishida, M; Nukatsuka, M; Okita, M; Toyooka, K; Tsujihara, K; Yoshimura, Y1
Atlef, N; Doll, N; Hermitte, L; Payan, MJ; Scheimann, A; Vague, P; Vialettes, B1
Gawler, DJ; Houslay, MD; Milligan, G; Wilson, A1
Cheng, HM; Kenyon, KR; Krauss, JM; Laing, RA; Miglior, S; Tsubota, K1
Abe, N; Kashiwagi, A; Kida, Y; Kodama, M; Nishio, Y; Saeki, Y; Shigeta, Y1
Berdanier, CD; Deaver, OE; McCusker, RH; Wander, RC1
Eizirik, DL; Malaisse, WJ; Sandler, S; Sener, A1
Jollow, DJ; Price, VF1
Gonzalez, AM; Hothersall, JS; McLean, P; Sochor, M1
Dickerson, JE; Garadi, R; Lou, MF; York, BM1
Cuezva, JM; Patel, MS1
Giacomelli, F; Kuo, TH; Wiener, J1
Randle, PJ; Vary, TC1
Robin, ED; Theodore, J1
Lazarus, SS; Shapiro, SH1
Brenner, RR1
Garland, PB1
Garland, PB; Newsholme, EA; Randle, PJ1
Arese, P; Bartels, H; Hohorst, HJ; Stratmann, D; Talke, H1
Kattermann, R; Kneer, P; Schmidt, H; Söling, HD1
Ihara, N1
Krebs, HA; Lund, P; Williamson, DH1
Anderson, J; Coulson, R1
Krebs, HA2
Ichiyama, A; Nakamura, S; Nishizuka, Y1
Loftus, S; Schein, PS1
Wieland, O1
Foster, DW; McGarry, JD1
Orishimo, MW; Whereat, AF1
Alberti, KG; Schein, PS; Williamson, DH1
Anderson, T; Cooney, DA; McMenamin, MG; Schein, PS1
Dajani, RM; Saheb, SE1
Clark, JB; Greenbaum, AL; McLean, P1
Kronfeld, DS; Raggi, F1
Graymore, CN; Towlson, MJ1
Burch, HB; Hornbrook, KR; Kalkhoff, RK; Kipnis, DM1
Gabbay, KH; O'Sullivan, JB1

Reviews

8 review(s) available for nad and Alloxan Diabetes

ArticleYear
Model of Streptozotocin-nicotinamide Induced Type 2 Diabetes: a Comparative Review.
    Current diabetes reviews, 2022, Volume: 18, Issue:8

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; NAD; Niacinamide; Poly(ADP-ribose) Polymerases; Rats; Streptozocin

2022
Sirtuins as therapeutic targets for improving delayed wound healing in diabetes.
    Journal of drug targeting, 2022, Volume: 30, Issue:9

    Topics: Animals; Diabetes Mellitus, Experimental; Humans; Matrix Metalloproteinase 9; NAD; Sirtuins; Wound Healing

2022
Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: lessons from insulin-producing pancreatic beta-cells.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Cyclic ADP-Ribose; Diabetes Mellitus, Experimental; DNA Repair; Humans; Insulin; Islets of Langerhans; Membrane Glycoproteins; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; Signal Transduction; Tryptophan

2003
Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes.
    Molecular and cellular biochemistry, 1981, Jun-09, Volume: 37, Issue:1

    Topics: Animals; Base Sequence; Cell Separation; Cell-Free System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA; DNA, Recombinant; Glucose; Insulin; Islets of Langerhans; Kynurenine; Molecular Weight; NAD; Nucleic Acid Hybridization; Poly(ADP-ribose) Polymerases; Proinsulin; Protein Biosynthesis; RNA; RNA, Messenger; Transcription, Genetic

1981
Hormonal regulation of protein degradation in skeletal and cardiac muscle.
    Life sciences, 1981, Jun-08, Volume: 28, Issue:23

    Topics: Adrenalectomy; Alanine; Animals; Corticosterone; Diabetes Mellitus, Experimental; Epinephrine; Fasting; Female; Glutamine; Growth Hormone; Hormones; Hydrocortisone; Insulin; Isoproterenol; Muscle Proteins; Myocardium; NAD; Pregnancy; Propranolol; Thyroxine; Triiodothyronine; Wounds and Injuries

1981
Endoneurial blood flow changes in diabetic rats.
    Diabetic medicine : a journal of the British Diabetic Association, 1993, Volume: 10 Suppl 2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Models, Biological; NAD; Oxidation-Reduction; Rats; Regional Blood Flow; Sciatic Nerve

1993
Extrapulmonary manifestations of respiratory disease with emphasis on abnormal electron (redox) metabolism.
    The Medical clinics of North America, 1973, Volume: 57, Issue:3

    Topics: Acidosis; Animals; Brain; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Electron Transport; Erythrocytes; Humans; Hypercapnia; Hypoxia; Liver; Lung Diseases; Macrophages; NAD; NADP; Nitrogen Dioxide; Oxidation-Reduction; Pulmonary Alveoli; Starvation

1973
Ketogenesis and its regulation.
    Advances in metabolic disorders, 1968, Volume: 3

    Topics: Acetoacetates; Acetone; Adenine Nucleotides; Adult; Animals; Cattle; Child; Citric Acid Cycle; Diabetes Mellitus, Experimental; Escherichia coli; Fatty Acids; Gluconeogenesis; Humans; Hydroxybutyrates; Ketone Bodies; Liver; Malates; NAD; Oxaloacetates; Rats

1968

Other Studies

125 other study(ies) available for nad and Alloxan Diabetes

ArticleYear
L-NAME Administration Enhances Diabetic Kidney Disease Development in an STZ/NAD Rat Model.
    International journal of molecular sciences, 2021, Nov-25, Volume: 22, Issue:23

    Topics: Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Male; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar

2021
Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: AMP-Activated Protein Kinases; Animals; Cytokines; Diabetes Mellitus, Experimental; Mice; NAD; Nicotinamide Phosphoribosyltransferase; Senescence-Associated Secretory Phenotype

2022
Contrast-Free FLIM Reveals Metabolic Changes in Pathological Islets of Langerhans.
    International journal of molecular sciences, 2022, Nov-08, Volume: 23, Issue:22

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Insulin; Islets of Langerhans; NAD; Pancreatitis, Chronic; Rats; Swine

2022
Drag-Reducing Polymers Improve Vascular Hemodynamics and Tissue Oxygen Supply in Mouse Model of Diabetes Mellitus.
    Advances in experimental medicine and biology, 2022, Volume: 1395

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Hemodynamics; Hypercapnia; Hyperglycemia; Mice; Mice, Inbred C57BL; Microcirculation; NAD; Oxygen; Polymers; Rats

2022
The effect of phytoprotectors on the functioning of liver NAD⁺- and NADP⁺-maliс enzymes in rats with alloxan diabetes.
    Biomeditsinskaia khimiia, 2023, Volume: 69, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Helianthus; Liver; Malate Dehydrogenase; NAD; NADP; Rats

2023
NAD metabolism modulates inflammation and mitochondria function in diabetic kidney disease.
    The Journal of biological chemistry, 2023, Volume: 299, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA, Mitochondrial; Inflammation; Interferons; Mice; Mitochondria; NAD; Nucleotidyltransferases

2023
Nicotinamide Prevents Diabetic Brain Inflammation via NAD+-Dependent Deacetylation Mechanisms.
    Nutrients, 2023, Jul-09, Volume: 15, Issue:14

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Encephalitis; Male; Mice; Mice, Inbred C57BL; NAD; Niacinamide

2023
Hyperpolarized [1-
    Yonsei medical journal, 2023, Volume: 64, Issue:10

    Topics: Agmatine; Animals; Brain; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lactic Acid; Mice; Mice, Inbred ICR; NAD; Pyruvic Acid

2023
CD38 Deficiency Alleviates Diabetic Cardiomyopathy by Coordinately Inhibiting Pyroptosis and Apoptosis.
    International journal of molecular sciences, 2023, Nov-06, Volume: 24, Issue:21

    Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Mammals; Mice; Myocytes, Cardiac; NAD; Oxidative Stress; Pyroptosis; Sirtuin 3; Stroke Volume; Ventricular Function, Left

2023
Dietary epicatechin improves survival and delays skeletal muscle degeneration in aged mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:1

    Topics: Aging; Animals; Catechin; Diabetes Mellitus, Experimental; Diet; Male; Metabolomics; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; NAD; Peroxisome Proliferator-Activated Receptors; Survival Rate

2019
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.
    Nature communications, 2019, 06-06, Volume: 10, Issue:1

    Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gene Expression Profiling; Gluconeogenesis; Glucose; Glycolysis; Insulin Secretion; Insulin-Secreting Cells; Metabolomics; Mice; Mice, Transgenic; Mitochondria; NAD; Oxidative Phosphorylation; Oxygen Consumption; Potassium Channels, Inwardly Rectifying; Proteomics

2019
Endogenous NAMPT dampens chemokine expression and apoptotic responses in stressed tubular cells.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:2

    Topics: Acrylamides; Animals; Apoptosis; Blotting, Western; Cell Line; Chemokine CCL2; Chemokine CCL5; Chemokines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression; Humans; Immunohistochemistry; Interleukin-6; Kidney; Kidney Tubules, Proximal; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Rats; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Necrosis Factor-alpha

2014
Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes.
    The Journal of nutritional biochemistry, 2014, Volume: 25, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; DNA, Mitochondrial; Energy Metabolism; Glucose; Glucose Tolerance Test; Insulin Resistance; Liver; Male; Mitochondrial Turnover; NAD; Niacinamide; Nicotinamide Phosphoribosyltransferase; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Inbred OLETF; Signal Transduction; Sirtuin 1; Sirtuins; Transcription Factors

2014
Reversal of neurobehavioral and neurochemical alterations in STZ-induced diabetic rats by FeTMPyP, a peroxynitrite decomposition catalyst and 1,5-Isoquinolinediol a poly(ADP-ribose) polymerase inhibitor.
    Neurological research, 2014, Volume: 36, Issue:7

    Topics: Acetylcholinesterase; Animals; Avoidance Learning; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; GPI-Linked Proteins; Hippocampus; Hypoglycemic Agents; Isoquinolines; Lipid Peroxidation; Male; Metalloporphyrins; NAD; Neurotransmitter Agents; Peroxynitrous Acid; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats, Sprague-Dawley; Streptozocin

2014
Theobromine increases NAD⁺/Sirt-1 activity and protects the kidney under diabetic conditions.
    American journal of physiology. Renal physiology, 2015, Feb-01, Volume: 308, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Kidney; Male; NAD; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sirtuin 1; Theobromine

2015
Impaired cytosolic NADH shuttling and elevated UCP3 contribute to inefficient citric acid cycle flux support of postischemic cardiac work in diabetic hearts.
    Journal of molecular and cellular cardiology, 2015, Volume: 79

    Topics: Animals; Aspartic Acid; Carbon-13 Magnetic Resonance Spectroscopy; Carrier Proteins; Citric Acid Cycle; Cytosol; Diabetes Mellitus, Experimental; Hemodynamics; Ion Channels; Malates; Male; Mice, Inbred C57BL; Mitochondrial Proteins; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NAD; Oxidation-Reduction; Perfusion; PPAR alpha; Uncoupling Protein 2; Uncoupling Protein 3

2015
Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response.
    Journal of translational medicine, 2015, Jan-16, Volume: 13

    Topics: Adenosine Triphosphate; Animals; Biomarkers; Blood Glucose; Body Weight; Cardiomyopathies; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; DNA Fragmentation; Glucose Tolerance Test; Inflammation; Kidney; Male; Malvaceae; Myocardium; NAD; Niacinamide; Organ Size; Oxidative Stress; Phytochemicals; Plant Extracts; Plant Leaves; Rats, Wistar

2015
Native fluorescence spectroscopy of blood plasma of rats with experimental diabetes: identifying fingerprints of glucose-related metabolic pathways.
    Journal of biomedical optics, 2015, Volume: 20, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Cross-Linking Reagents; Diabetes Mellitus, Experimental; Fluorescence; Gene Expression Regulation; Glucose; Glycosylation; Hyperglycemia; Male; Metabolic Networks and Pathways; NAD; NADP; Plasma; Rats; Rats, Wistar; Spectrometry, Fluorescence

2015
Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation.
    Antioxidants & redox signaling, 2010, Volume: 12, Issue:1

    Topics: Animals; Blood Vessels; Diabetes Mellitus, Experimental; Male; NAD; Nervous System; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Sorbitol

2010
Dietary zinc reduction, pyruvate supplementation, or zinc transporter 5 knockout attenuates β-cell death in nonobese diabetic mice, islets, and insulinoma cells.
    The Journal of nutrition, 2012, Volume: 142, Issue:12

    Topics: Animals; Benzamides; Calcium Channel Blockers; Carrier Proteins; Cell Line, Tumor; Diabetes Mellitus, Experimental; Dietary Supplements; Female; Insulinoma; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; NAD; Naphthols; Pancreatic Neoplasms; Pyruvic Acid; Reactive Oxygen Species; Streptozocin; Zinc

2012
Increased glucose sensitivity of stimulus-secretion coupling in islets from Psammomys obesus after diet induction of diabetes.
    Diabetes, 2002, Volume: 51, Issue:8

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Gerbillinae; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Membrane Potentials; Mitochondria; NAD; NADP; Oxidation-Reduction

2002
Responsiveness of renal glomeruli to adenosine in streptozotocin-induced diabetic rats dependent on hyperglycaemia level.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2003, Volume: 54, Issue:1

    Topics: Adenosine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hemodynamics; Inulin; Kidney Glomerulus; Male; NAD; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Renal Plasma Flow; Xanthines

2003
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes.
    Diabetologia, 2003, Volume: 46, Issue:9

    Topics: Adenosine Triphosphate; Animals; Antigens, Polyomavirus Transforming; Antioxidants; Cell Death; Cell Line, Tumor; Cell Transformation, Neoplastic; Diabetes Mellitus, Experimental; Etoposide; Insulinoma; Interferon-gamma; Islets of Langerhans; NAD; Necrosis; Pancreatic Neoplasms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Staurosporine; Tumor Necrosis Factor-alpha; Zinc

2003
The effect of pituitary growth hormone and of insulin on the level of oxidized and reduced coenzyme I in the livers of normal and diabetic rats.
    The Biochemical journal, 1956, Volume: 63, Issue:1

    Topics: Animals; Coenzymes; Diabetes Mellitus, Experimental; Growth Hormone; Insulin; Liver; NAD; Rats

1956
The inactivation of cortisol in experimental diabetic animals.
    Medical journal of Osaka University, 1963, Volume: 13

    Topics: Anatomy; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Diabetes Mellitus; Diabetes Mellitus, Experimental; Hepatitis; Hepatitis A; Hydrocortisone; Insulin; NAD; Niacin; Niacinamide; Steroids; Testosterone

1963
The rate of generation of reduced nicotinamide adenine dinucleotide and reduced nicotinamide adenine dinucleotide phosphate in the liver of normal and alloxan diabetic rats.
    The Journal of biological chemistry, 1963, Volume: 238

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Liver; NAD; NADP; Rats

1963
Pyridine nucleotides in normal and diabetic rat lenses.
    Experimental eye research, 1962, Volume: 1

    Topics: Animals; Diabetes Mellitus, Experimental; Lens, Crystalline; Lenses; NAD; NADP; Nucleotides; Pyridines; Rats

1962
Ratios of total oxidized to total reduced diphosphopyridine nucleotides in livers of normal and diabetic rats.
    Endocrinology, 1963, Volume: 72

    Topics: Animals; Diabetes Mellitus, Experimental; Liver; NAD; Oxidation-Reduction; Rats

1963
STUDIES ON CARBON DIOXIDE FIXATION IN NORMAL AND ALLOXAN-DIABETIC ANIMALS.
    Biochimica et biophysica acta, 1963, Aug-13, Volume: 74

    Topics: Adenosine Triphosphate; Alloxan; Animals; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Diabetes Mellitus, Experimental; Keto Acids; Lactates; Liver; NAD; Pharmacology; Pyruvates; Rats; Research

1963
A CRITICAL STUDY OF PYRIDINE NUCLEOTIDE CONCENTRATIONS IN NORMAL FED, NORMAL FASTED, AND DIABETIC RAT LIVER.
    Metabolism: clinical and experimental, 1964, Volume: 13

    Topics: Animals; Diabetes Mellitus, Experimental; Diet; Fasting; Fluorescence; Liver; Metabolism; Mitochondria; NAD; NADP; Nucleotides; Pyridines; Rats; Research

1964
DIABETIC METABOLISM. I. CARBOHYDRATE UTILIZATION AND HIGH ENERGY PHOSPHATE FORMATION IN HEART HOMOGENATES FROM NORMAL AND ALLOXAN-DIABETIC RATS.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Alloxan; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Fructose; Glucose; Heart; L-Lactate Dehydrogenase; Lactates; Metabolism; Myocardium; NAD; Phosphates; Rats; Research; Spectrophotometry

1964
[ON THE EFFECT OF INSULIN ON THE NAD-SYSTEM AND THE PHOSPHORYLATION OF ADENINE NUCLEOTIDES IN THE LIVER].
    Klinische Wochenschrift, 1964, Mar-01, Volume: 42

    Topics: Adenine Nucleotides; Animals; Diabetes Mellitus, Experimental; Insulin; Liver; Liver Function Tests; Metabolism; NAD; Pharmacology; Phosphorylation; Physiology; Research

1964
THE INTRACELLULAR LOCALIZATION OF AN ENZYMATIC DEFECT OF LIPID METABOLISM IN DIABETIC RATS.
    Biochimica et biophysica acta, 1964, Apr-20, Volume: 84

    Topics: Adipose Tissue; Animals; Chromatography; Diabetes Mellitus, Experimental; Insulin; Lipid Metabolism; Liver; Manometry; Metabolic Diseases; Microsomes; NAD; NADP; Oleic Acid; Oxygenases; Pharmacology; Rats; Research; Stearic Acids

1964
HISTOCHEMISTRY OF THE RETINA IN THE ALLOXAN-DIABETIC RAT.
    The British journal of ophthalmology, 1963, Volume: 47

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Dihydrolipoamide Dehydrogenase; Histocytochemistry; Histological Techniques; L-Lactate Dehydrogenase; Malate Dehydrogenase; NAD; Rats; Research; Retina; Succinate Dehydrogenase; Tissue Culture Techniques; Transferases; Uracil Nucleotides

1963
[ON THE MECHANISM OF INCREASED KETONE BODY FORMATION. I. REDOX STATUS OF LIVER DPN UNDER CONDITIONS OF KETOSIS IN VIVO].
    Biochemische Zeitschrift, 1963, Dec-03, Volume: 339

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Coma; Diabetic Ketoacidosis; Glycerophosphates; Ketone Bodies; Ketosis; Lactates; Liver; Malates; Metabolism; NAD; Oxidation-Reduction; Pyruvates; Rats; Research

1963
STUDIES ON THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE. II. A ROLE OF PICOLINIC CARBOXYLASE IN THE BIOSYNTHESIS OF NICOTINAMIDE ADENINE DINUCLEOTIDE FROM TRYPTOPHAN IN MAMMALS.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Animals; Carbon Isotopes; Cats; Diabetes Mellitus, Experimental; Glutarates; Kidney; Kynurenine; Ligases; Liver; Mammals; Metabolism; NAD; Nucleotides; Phosphotransferases; Radiometry; Rats; Research; Transferases; Tryptophan

1965
THE EFFECT OF DIFFERENT HORMONAL CONDITIONS ON THE CONCENTRATION AND OXIDOREDUCTION STATE OF THE NICOTINAMIDE NUCLEOTIDES OF RAT LIVER.
    The Biochemical journal, 1965, Volume: 95

    Topics: Adrenalectomy; Animals; Carbohydrate Metabolism; Cortisone; Diabetes Mellitus, Experimental; Glucagon; Glucose; Glucosephosphate Dehydrogenase; Growth Hormone; Lipid Metabolism; Liver; NAD; NADP; Niacinamide; Nucleotides; Oxidation-Reduction; Oxidoreductases; Pharmacology; Phosphogluconate Dehydrogenase; Rats; Research; Toxicology

1965
SUBCELLULAR DISTRIBUTION AND PROPERTIES OF HEPATIC GLUCOSE DEHYDROGENASES OF SELECTED VERTEBRATES.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Alcohol Oxidoreductases; Amphibians; Animals; Birds; Cattle; Chromatography; Diabetes Mellitus, Experimental; Fishes; Glucose Dehydrogenases; Glucose-6-Phosphatase; Guinea Pigs; Haplorhini; Hydrogen-Ion Concentration; Liver; NAD; Poultry; Rats; Research; Snakes; Spectrophotometry; Swine; Vertebrates

1965
p22phox-derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells.
    Diabetes research and clinical practice, 2004, Volume: 64, Issue:1

    Topics: Animals; Aorta; Base Sequence; Cell Division; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Primers; Gene Expression Regulation, Enzymologic; Male; Membrane Transport Proteins; Muscle, Smooth, Vascular; NAD; NADH, NADPH Oxidoreductases; NADPH Dehydrogenase; NADPH Oxidases; Oligonucleotides, Antisense; Phosphoproteins; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Transfection; Xanthine

2004
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.
    Diabetologia, 2004, Volume: 47, Issue:4

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diuretics; Enzyme Inhibitors; Male; Motor Neurons; NAD; Neural Conduction; Neurons, Afferent; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Sciatic Neuropathy; Sorbitol

2004
Purine nucleotides and their metabolites in erythrocytes of streptozotocin diabetic rats.
    Diabetes & metabolism, 2004, Volume: 30, Issue:6

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Erythrocytes; Guanine Nucleotides; Inosine Monophosphate; Male; NAD; NADP; Purine Nucleotides; Rats; Rats, Wistar

2004
Ethanol increases mitochondrial cytochrome P450 2E1 in mouse liver and rat hepatocytes.
    FEBS letters, 2005, Dec-19, Volume: 579, Issue:30

    Topics: Animals; Blotting, Western; Cells, Cultured; Cytochrome P-450 CYP2E1; Diabetes Mellitus, Experimental; Ethanol; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Obese; Microsomes, Liver; Mitochondria, Liver; NAD; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Time Factors

2005
Reexamining the hyperglycemic pseudohypoxia hypothesis of diabetic oculopathy.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:6

    Topics: Adenosine Triphosphate; Aldehyde Reductase; Animals; Cell Culture Techniques; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Epithelial Cells; Glucose; Humans; Hyperglycemia; Hypoxia; Lactic Acid; Lens, Crystalline; NAD; Pigment Epithelium of Eye; Pyruvic Acid; Rabbits; Rats; Rats, Sprague-Dawley; Retina

2006
NAD+-induced vasotoxicity in the pericyte-containing microvasculature of the rat retina: effect of diabetes.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:11

    Topics: Adenosine Diphosphate; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Apoptosis; Benzoxazoles; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fluorescent Dyes; Microscopy, Fluorescence; NAD; Pericytes; Purinergic P2 Receptor Antagonists; Quinolinium Compounds; Rats; Rats, Long-Evans; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Retinal Vessels

2006
Modulation of vascular reactivity in normal, hypertensive and diabetic rat aortae by a non-antioxidant flavonoid.
    Pharmacological research, 2007, Volume: 55, Issue:5

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Enzyme Inhibitors; Flavones; Flavonoids; Guanylate Cyclase; Hypertension; Indomethacin; Male; Methylene Blue; Muscle, Smooth, Vascular; NAD; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation; Vasodilator Agents

2007
Intestinal Auerbach plexus structures with NADH histochemistry in three strains of spontaneous diabetic rats.
    Acta gastroenterologica Latinoamericana, 2007, Volume: 37, Issue:2

    Topics: Animals; Colon; Diabetes Mellitus, Experimental; Histocytochemistry; Intestine, Small; Male; Microscopy, Electron, Scanning; Muscle, Smooth; Myenteric Plexus; NAD; Rats; Rats, Inbred Strains; Rats, Wistar; Staining and Labeling

2007
Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy.
    Life sciences, 2008, Mar-12, Volume: 82, Issue:11-12

    Topics: 1-Naphthylamine; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Humans; Male; NAD; Naphthalimides; Neural Conduction; Pain Measurement; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones; Rats; Rats, Sprague-Dawley; Streptozocin

2008
Brown adipose tissue metabolism in streptozotocin-diabetic rats.
    Endocrinology, 1983, Volume: 113, Issue:2

    Topics: Adipose Tissue, Brown; Animals; Coenzyme A Ligases; Diabetes Mellitus, Experimental; Electric Stimulation; Kinetics; Male; NAD; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins

1983
Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice.
    Toxicology and applied pharmacology, 1983, Volume: 70, Issue:1

    Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; NAD; Niacinamide

1983
Nicotinamide does not protect islet B-cell metabolism against alloxan toxicity.
    Diabetes, 1984, Volume: 33, Issue:10

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; NAD; Niacinamide; Oxidation-Reduction; Oxygen Consumption; Proinsulin

1984
Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.
    Biochemical and biophysical research communications, 1980, Jul-16, Volume: 95, Issue:1

    Topics: Amides; Animals; Cell Nucleus; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; NAD; NAD+ Nucleosidase; Niacinamide; Picolinic Acids; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proinsulin; Rats; Streptozocin

1980
Does an increase in the ratio of cytoplasmic NADPH to NADP+ accompanied by a decrease in the ratio of cytoplasmic NADH to NAD+ mediate the actions of insulin?
    Medical hypotheses, 1982, Volume: 9, Issue:2

    Topics: Amino Acids; Animals; Blood Glucose; Cytoplasm; Diabetes Mellitus, Experimental; Humans; Insulin; Lipid Metabolism; Mitochondria; NAD; NADP; Oxidation-Reduction; Phosphoric Diester Hydrolases; Protein Biosynthesis; Pyruvate Dehydrogenase Complex; Ribosomes; Stimulation, Chemical

1982
DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors.
    Princess Takamatsu symposia, 1983, Volume: 13

    Topics: Adenoma, Islet Cell; Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA; Enzyme Activation; Insulinoma; Islets of Langerhans; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Rats; Streptozocin

1983
Modulation of beta-oxidation and proton conductance pathway of brown adipose tissue in hypo- and hyperinsulinemic states.
    FEBS letters, 1984, Jan-23, Volume: 166, Issue:1

    Topics: Adipose Tissue; Animals; Body Temperature Regulation; Diabetes Mellitus, Experimental; Fatty Acids; Guanosine Diphosphate; Hydrogen-Ion Concentration; Insulin; Mitochondria; NAD; Oxidation-Reduction; Proteins; Rats

1984
Defective oxidative metabolism of heart mitochondria from genetically diabetic mice.
    Diabetes, 1983, Volume: 32, Issue:9

    Topics: Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Hydroxy Acids; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria, Heart; Myocardium; NAD; Oxidative Phosphorylation; Oxygen Consumption; Palmitoylcarnitine; Pyruvates

1983
DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin.
    Biochemical and biophysical research communications, 1981, Dec-15, Volume: 103, Issue:3

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; DNA; Islets of Langerhans; Liver; Male; NAD; Rats; Rats, Inbred Strains; Streptozocin

1981
Time-course of mitochondrial and cytoplasmic oxidoreduction state of rat liver following an intravenous glucose load.
    The Journal of laboratory and clinical medicine, 1980, Volume: 95, Issue:5

    Topics: Animals; Blood Glucose; Cytoplasm; Diabetes Mellitus, Experimental; Glucose; Hydroxybutyrate Dehydrogenase; Infusions, Parenteral; Insulin; Lactates; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Rats; Time Factors

1980
The newborn of diabetic rat. II. Impaired gluconeogenesis in the postnatal period.
    Pediatric research, 1982, Volume: 16, Issue:8

    Topics: Adenine Nucleotides; Animals; Animals, Newborn; Carbon Radioisotopes; Diabetes Mellitus, Experimental; Female; Gluconeogenesis; Glutathione Peroxidase; Insulin; Lactates; Liver; NAD; Phosphoenolpyruvate Carboxykinase (GTP); Pregnancy; Pregnancy in Diabetics; Prenatal Exposure Delayed Effects; Proteins; Rats; Time Factors

1982
NAD synthesis from nicotinic acid by the hepatocytes prepared from diabetic rats.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1995, Volume: 65, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Carbon Radioisotopes; Cells, Cultured; Diabetes Mellitus, Experimental; Hydroxybutyrates; Ketone Bodies; Liver; Male; NAD; Niacin; Rats; Rats, Sprague-Dawley; Streptozocin

1995
Protective mechanism of glucose against alloxan-induced pancreatic beta-cell damage.
    Biochemical and biophysical research communications, 1995, May-05, Volume: 210, Issue:1

    Topics: Alloxan; Animals; Calcium; Diabetes Mellitus, Experimental; Glucose; Hydrogen Peroxide; Insulin; Insulin Secretion; Islets of Langerhans; Male; NAD; Rats; Rats, Sprague-Dawley; Time Factors

1995
Changes of corneal redox state in diabetic animal models.
    Cornea, 1995, Volume: 14, Issue:2

    Topics: Animals; Cornea; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Corneal; Epithelium; Flavoproteins; Fluorescence; Fluorometry; Mice; Mice, Inbred NOD; NAD; Organ Culture Techniques; Oxidation-Reduction; Pyrimidine Nucleotides; Rabbits

1995
Control of sorbitol metabolism in renal inner medulla of diabetic rats: regulation by substrate, cosubstrate and products of the aldose reductase reaction.
    Biochimica et biophysica acta, 1993, Nov-25, Volume: 1225, Issue:1

    Topics: Aldehyde Reductase; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Kinetics; Male; NAD; NADP; Oxidation-Reduction; Rats; Rats, Wistar; Sorbitol

1993
Interactions between the sorbitol pathway, non-enzymatic glycation, and diabetic vascular dysfunction.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Animals; Blood Flow Velocity; Blood Glucose; Capillary Permeability; Cattle; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycated Serum Albumin; Glycation End Products, Advanced; Glycosylation; Humans; Male; NAD; Nitric Oxide; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Serum Albumin; Serum Albumin, Bovine; Sorbitol; Superoxides

1996
Hepatic glucose production from L-alanine is absent in perfused liver of diabetic rats.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:2

    Topics: Alanine; Alloxan; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Gluconeogenesis; Glucose; Glycerol; Infusions, Intravenous; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Software; Sorbitol; Streptozocin

1997
Endogenous mono-ADP-ribosylation in retina and peripheral nervous system. Effects of diabetes.
    Advances in experimental medicine and biology, 1997, Volume: 419

    Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Diabetes Mellitus, Experimental; Insulin; NAD; Peripheral Nervous System; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Retina; Silymarin; Superior Cervical Ganglion

1997
Changes in the redox state in the retina and brain during the onset of diabetes in rats.
    Neurochemical research, 1998, Volume: 23, Issue:6

    Topics: Animals; Cerebral Cortex; Diabetes Mellitus, Experimental; L-Lactate Dehydrogenase; Lactic Acid; Lens, Crystalline; Liver; NAD; Oxidation-Reduction; Pigment Epithelium of Eye; Pyruvic Acid; Rats; Retina

1998
Diabetes-induced changes in lens antioxidant status, glucose utilization and energy metabolism: effect of DL-alpha-lipoic acid.
    Diabetologia, 1998, Volume: 41, Issue:12

    Topics: Adenine Nucleotides; Animals; Antioxidants; Diabetes Mellitus, Experimental; Energy Metabolism; Fructose; Glucose; Glutathione; Glycolysis; Lens, Crystalline; Male; NAD; NADP; Oxidative Stress; Rats; Rats, Wistar; Sorbitol; Thioctic Acid

1998
Poly(ADP-ribose)polymerase activation determines strain sensitivity to streptozotocin-induced beta cell death in inbred mice.
    Journal of molecular endocrinology, 1999, Volume: 22, Issue:1

    Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Disease Susceptibility; DNA Damage; DNA Repair; Drug Resistance; Enzyme Activation; Hydrogen Peroxide; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondria; NAD; Poly(ADP-ribose) Polymerases; Species Specificity; Streptozocin

1999
Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-02, Volume: 96, Issue:5

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Exons; Immunity, Innate; Islets of Langerhans; Mice; Mice, Knockout; NAD; Poly(ADP-ribose) Polymerases; Recombination, Genetic; Streptozocin

1999
Evaluation of a sorbitol dehydrogenase inhibitor on diabetic peripheral nerve metabolism: a prevention study.
    Diabetologia, 1999, Volume: 42, Issue:10

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fructose; Glutathione; L-Iditol 2-Dehydrogenase; Male; Malondialdehyde; Mitochondria; NAD; Oxidative Stress; Peripheral Nerves; Rats; Rats, Wistar; Sciatic Nerve; Spectrometry, Fluorescence

1999
An enzymatic assay for myo-inositol in tissue samples.
    Journal of biochemical and biophysical methods, 2000, Jul-10, Volume: 44, Issue:1-2

    Topics: Animals; Biochemistry; Diabetes Mellitus, Experimental; Fluorometry; Inositol; Lens, Crystalline; Malate Dehydrogenase; Male; Models, Chemical; NAD; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sciatic Nerve; Sugar Alcohol Dehydrogenases

2000
Evaluation of alpha(1)-adrenoceptor antagonist on diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, Volume: 14, Issue:11

    Topics: Adrenergic alpha-Antagonists; Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Creatine; Diabetes Mellitus, Experimental; Glutathione; Hexoses; Inositol; Male; Malondialdehyde; Mitochondria; NAD; Oxidative Stress; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Regional Blood Flow; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Sorbitol; Taurine

2000
Evaluation of an aldose reductase inhibitor on lens metabolism, ATPases and antioxidative defense in streptozotocin-diabetic rats: an intervention study.
    Diabetologia, 2000, Volume: 43, Issue:8

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Aldehyde Reductase; Animals; Antioxidants; Ca(2+) Mg(2+)-ATPase; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Imidazoles; Imidazolidines; Inositol; Lens, Crystalline; Male; NAD; NADP; Proton-Translocating ATPases; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sorbitol

2000
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
    Pharmacology, 2001, Volume: 62, Issue:3

    Topics: Adrenergic alpha-Antagonists; Ammonia; Animals; Antioxidants; Cell Fractionation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fructose; Glucose; Glutamic Acid; Imidazoles; Imidazolidines; Ketoglutaric Acids; Lactic Acid; Male; Mitochondria; NAD; Oxidation-Reduction; Piperazines; Prazosin; Pyrimidines; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Retina; Sorbitol; Thioctic Acid

2001
Melatonin protects against streptozotocin, but not interleukin-1beta-induced damage of rodent pancreatic beta-cells.
    Journal of pineal research, 2001, Volume: 30, Issue:3

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Free Radical Scavengers; Glucose; Hyperglycemia; Insulin; Interleukin-1; Islets of Langerhans; Male; Melatonin; Mice; Mice, Inbred C57BL; NAD; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Streptozocin

2001
Rates of gluconeogenesis in perfused liver of alloxan-diabetic fed rats.
    Research communications in molecular pathology and pharmacology, 2000, Volume: 107, Issue:1-2

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Fructose; Gluconeogenesis; Glucose; Glutamine; In Vitro Techniques; Kinetics; Lactic Acid; Liver; Male; NAD; Perfusion; Pyruvic Acid; Rats; Rats, Wistar; Uric Acid

2000
An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:1

    Topics: Aldehyde Reductase; Animals; Antioxidants; Cytosol; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Imidazoles; Imidazolidines; Lipid Peroxidation; Mitochondria; Models, Biological; NAD; Neural Conduction; Oxidation-Reduction; Oxidative Stress; Peripheral Nerves; Rats

2002
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2001, Volume: 50, Issue:11

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Arthritis; Colitis; Collagen; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endotoxemia; Enzyme Inhibitors; Male; Mice; Mice, Inbred DBA; NAD; Peritonitis; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Uveitis

2001
Regulatory function of pyruvate dehydrogenase and the mitochondrion in lipogenesis.
    Lipids, 1975, Volume: 10, Issue:12

    Topics: Acetates; Adenine Nucleotides; Adenosine Triphosphatases; Animals; Cytoplasm; Diabetes Mellitus, Experimental; Dietary Fats; Fatty Acids; Lipids; Male; Mitochondria, Liver; NAD; NADP; Phosphates; Pyruvate Dehydrogenase Complex; Rats; Starvation

1975
Lactic acidosis: an experimental model.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:3

    Topics: Acidosis; Animals; Bicarbonates; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Disease Models, Animal; Hydrogen-Ion Concentration; Hydroxybutyrates; Lactates; NAD; Pyruvates; Rabbits

1976
[Activity of NAD- and NADP-dependent malate dehydrogenase isoenzymes in the myocardium of rabbits with alloxan diabetes].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 80, Issue:7

    Topics: Animals; Cytosol; Diabetes Mellitus, Experimental; Isoenzymes; Malate Dehydrogenase; Mitochondria, Muscle; Myocardium; NAD; NADP; Rabbits

1975
Studies on dehydrogenases of the glucuronate-xylulose cycle in the livers of diabetic mice and rats.
    Diabetes, 1979, Volume: 28, Issue:9

    Topics: Aging; Alcohol Oxidoreductases; Animals; Carbohydrate Dehydrogenases; Diabetes Mellitus, Experimental; Glucuronates; Liver; Male; Mice; NAD; NADP; Pentoses; Rats; Xylulose

1979
Rat-liver cell compartition as revealed by correlations between redox-quotient changes following alloxan treatment, starvation, carbohydrate- and fat-diet.
    Archives internationales de physiologie et de biochimie, 1978, Volume: 86, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Dietary Fats; Energy Metabolism; Kinetics; L-Lactate Dehydrogenase; Liver; Malate Dehydrogenase; Male; Mathematics; NAD; NADP; Oxidation-Reduction; Rats; Starvation; Subcellular Fractions

1978
Regulation of pyruvate dehydrogenase in rat heart. Mechanism of regulation of proportions of dephosphorylated and phosphorylated enzyme by oxidation of fatty acids and ketone bodies and of effects of diabetes: role of coenzyme A, acetyl-coenzyme A and red
    The Biochemical journal, 1976, Feb-15, Volume: 154, Issue:2

    Topics: Acetates; Acetyl Coenzyme A; Adenosine Triphosphate; Animals; Caprylates; Carnitine; Cell Membrane; Coenzyme A; Diabetes Mellitus, Experimental; Fatty Acids; Heart; In Vitro Techniques; Ketoglutaric Acids; Ketone Bodies; Malates; Male; Mitochondria, Muscle; Myocardium; NAD; Oligomycins; Palmitates; Perfusion; Phosphates; Pyruvate Dehydrogenase Complex; Pyruvates; Rats; Succinates

1976
Reduction of streptozotocin toxicity by 3-O-methyl-D-glucose with enhancement of antitumor activity in murine L1210 leukemia.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: Animals; Diabetes Mellitus, Experimental; Drug Interactions; Drug Therapy, Combination; Leukemia L1210; Liver; Male; Methylglucosides; Methylglycosides; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; NAD; Niacinamide; Streptozocin

1977
The effect of streptozotocin diabetes on the vasoactive intestinal peptide receptor/effector system in membranes from rat ventral prostate.
    Endocrinology, 1992, Volume: 131, Issue:4

    Topics: Adenosine Diphosphate Ribose; Animals; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Male; Membranes; NAD; Prostate; Rats; Rats, Wistar; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide

1992
Evidence for impaired coupling of receptors to Gi protein in adipocytes from streptozocin-induced diabetic rats.
    Diabetes, 1991, Volume: 40, Issue:1

    Topics: Adipose Tissue; Alprostadil; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Lipolysis; Male; Molecular Weight; NAD; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Purinergic; Reference Values; Virulence Factors, Bordetella

1991
Spectrophotometric enzymatic assay for S-3-hydroxyisobutyrate.
    Analytical biochemistry, 1990, Feb-01, Volume: 184, Issue:2

    Topics: Alcohol Oxidoreductases; Animals; Diabetes Mellitus, Experimental; Hydroxybutyrates; Male; NAD; Rabbits; Rats; Rats, Inbred Strains; Spectrophotometry; Substrate Specificity

1990
Ethylidene glucose-substituted new analogue of streptozotocin cannot induce diabetes: study on the basis of structure and activity relationship.
    Molecular and cellular endocrinology, 1989, Volume: 62, Issue:2

    Topics: Animals; Autoradiography; Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus, Experimental; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Male; Monosaccharide Transport Proteins; NAD; Rats; Rats, Inbred Strains; Streptozocin

1989
High dose nicotinamide fails to prevent diabetes in BB rats.
    Autoimmunity, 1989, Volume: 5, Issue:1-2

    Topics: Age Factors; Animals; Autoimmune Diseases; Blood Glucose; Cyclosporine; Deferoxamine; Diabetes Mellitus, Experimental; DNA Damage; Drug Evaluation, Preclinical; Hyperplasia; Insulin; Insulin Secretion; Islets of Langerhans; Models, Biological; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Inbred BB

1989
Multiple defects occur in the guanine nucleotide regulatory protein system in liver plasma membranes of obese (fa/fa) but not lean (Fa/Fa) Zucker rats: loss of functional Gi and abnormal Gs function.
    Cellular signalling, 1989, Volume: 1, Issue:1

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Blotting, Western; Cell Membrane; Cholera Toxin; Colforsin; Diabetes Mellitus, Experimental; Glucagon; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Insulin Resistance; Liver; Male; NAD; Obesity; Pertussis Toxin; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Rats, Zucker; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Virulence Factors, Bordetella

1989
Lens redox fluorometry: pyridine nucleotide fluorescence and analysis of diabetic lens.
    Experimental eye research, 1989, Volume: 49, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Fluorescence; Fluorometry; Lens, Crystalline; NAD; Oxidation-Reduction; Rabbits; Rats; Rats, Inbred Strains

1989
Deficiency of cardiac beta-adrenergic receptor in streptozocin-induced diabetic rats.
    Diabetes, 1988, Volume: 37, Issue:9

    Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Diabetes Mellitus, Experimental; Kinetics; Male; Membrane Proteins; Myocardium; NAD; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Reference Values

1988
Diet effects on membrane phospholipid fatty acids and mitochondrial function in BHE rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Aspartic Acid; Coconut Oil; Corn Oil; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Fats; Fatty Acids; Glycerophosphates; Malates; Male; Membrane Lipids; Mitochondria, Liver; NAD; Oils; Phospholipids; Plant Oils; Rats; Rats, Mutant Strains

1986
Defective catabolism of D-glucose and L-glutamine in mouse pancreatic islets maintained in culture after streptozotocin exposure.
    Endocrinology, 1988, Volume: 123, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Cells, Cultured; Cytosol; Diabetes Mellitus, Experimental; Glucokinase; Glucose; Glutamate Dehydrogenase; Glutamine; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Islets of Langerhans; Male; Mice; Mitochondria; NAD; NADP; Streptozocin

1988
The role of poly(ADP-ribose) synthetase in the development of insulin-dependent diabetes and islet B-cell regeneration.
    Biomedica biochimica acta, 1985, Volume: 44, Issue:1

    Topics: Alloxan; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; DNA Repair; DNA Replication; Islets of Langerhans; Methylation; NAD; NAD+ Nucleosidase; Poly(ADP-ribose) Polymerases; Streptozocin

1985
Strain differences in susceptibility of normal and diabetic rats to acetaminophen hepatotoxicity.
    Biochemical pharmacology, 1986, Feb-15, Volume: 35, Issue:4

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Experimental; Disease Susceptibility; Glucuronosyltransferase; Half-Life; Liver; Male; Microsomes, Liver; NAD; Rats; Rats, Inbred Strains; Species Specificity; Uridine Diphosphate Glucose; Uridine Diphosphate Glucose Dehydrogenase; Uridine Diphosphate Glucuronic Acid

1986
Effect of aldose reductase inhibitor (sorbinil) on integration of polyol pathway, pentose phosphate pathway, and glycolytic route in diabetic rat lens.
    Diabetes, 1986, Volume: 35, Issue:11

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glutathione; Imidazoles; Imidazolidines; Lens, Crystalline; NAD; NADP; Pentose Phosphate Pathway; Sugar Alcohol Dehydrogenases

1986
Glutathione depletion in the lens of galactosemic and diabetic rats.
    Experimental eye research, 1988, Volume: 46, Issue:4

    Topics: Aldehyde Reductase; Aminoisobutyric Acids; Animals; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Fluorenes; Galactitol; Galactosemias; Glutathione; Glutathione Reductase; Hydantoins; Lens, Crystalline; Male; NAD; NADP; Rats; Rats, Inbred Strains; Sorbitol

1988
Effect of glucose and insulin administration on hepatic adenylate energy charge and the cytosolic redox state in the neonates of normal and insulin-treated diabetic rats.
    Biology of the neonate, 1985, Volume: 48, Issue:4

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Animals, Newborn; Cytosol; Diabetes Mellitus, Experimental; Energy Metabolism; Female; Glucose; Insulin; Lactates; Lactic Acid; Liver; NAD; Oxidation-Reduction; Pregnancy; Pregnancy in Diabetics; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains

1985
Oxidative metabolism of Polytron versus Nagarse mitochondria in hearts of genetically diabetic mice.
    Biochimica et biophysica acta, 1985, Jan-23, Volume: 806, Issue:1

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Animals; Cell Fractionation; Diabetes Mellitus, Experimental; Malates; Mice; Mice, Inbred C57BL; Microscopy, Electron; Mitochondria, Heart; NAD; Oxidation-Reduction; Oxidative Phosphorylation; Palmitoylcarnitine; Pyruvates; Pyruvic Acid; Succinates; Succinic Acid

1985
Regulation of pyruvate dehydrogenase complex activity during myocardial ischemia.
    Advances in myocardiology, 1985, Volume: 6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coronary Disease; Diabetes Mellitus, Experimental; Dietary Fats; Heart Arrest, Induced; Male; Myocardial Contraction; Myocardium; NAD; Oxygen Consumption; Perfusion; Potassium; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains

1985
Influence of nicotinamide and pyridine nucleotides on streptozotocin and alloxan-induced pancreatic B cell cytotoxicity.
    Diabetes, 1973, Volume: 22, Issue:7

    Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; Mice; NAD; NADP; Necrosis; Niacinamide; Pancreas; Rats; Streptozocin; Time Factors

1973
The oxidative desaturation of unsaturated fatty acids in animals.
    Molecular and cellular biochemistry, 1974, Mar-08, Volume: 3, Issue:1

    Topics: Adenosine Triphosphate; Age Factors; Animals; Arachidonic Acids; Coenzyme A; Diabetes Mellitus, Experimental; Diet; Dietary Proteins; Fatty Acid Desaturases; Glucose; Glycolysis; Insulin; Kinetics; Linoleic Acids; Linolenic Acids; Magnesium; Microsomes, Liver; NAD; NADP; Oleic Acids; Phospholipids; Rats

1974
Some kinetic properties of pig-heart oxoglutarate dehydrogenase that provide a basis for metabolic control of the enzyme activity and also a stoicheiometric assay for coenzyme A in tissue extracts.
    The Biochemical journal, 1964, Volume: 92, Issue:2

    Topics: Animals; Coenzyme A; Diabetes Mellitus, Experimental; Enzyme Repression; In Vitro Techniques; Ketoglutaric Acids; Kinetics; Myocardium; NAD; Oxidoreductases; Spectrophotometry; Swine; Tissue Extracts

1964
Regulation of glucose uptake by muscle. 9. Effects of fatty acids and ketone bodies, and of alloxan-diabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat h
    The Biochemical journal, 1964, Volume: 93, Issue:3

    Topics: Acetoacetates; Animals; Butyrates; Carbon Dioxide; Diabetes Mellitus, Experimental; Diaphragm; Fatty Acids; Glucose; Glycerophosphates; Heart; Hydroxybutyrates; Hypoxia; In Vitro Techniques; Ketone Bodies; Lactates; Muscles; Myocardium; NAD; Palmitic Acids; Perfusion; Phosphates; Pyruvates; Rats; Salicylates; Starvation

1964
L(+) lactic acid and the steady state of cellular red/ox-systems.
    Annals of the New York Academy of Sciences, 1965, Jul-31, Volume: 119, Issue:3

    Topics: Animals; Blood; Diabetes Mellitus, Experimental; Dietary Fats; Fatty Acids; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Homeostasis; In Vitro Techniques; Insulin; Lactates; Liver; Muscles; NAD; Oxidoreductases; Pyruvates

1965
The redox state of NAD+-NADH systems in rat liver during ketosis, and the so-called "triosephosphate block".
    Biochimica et biophysica acta, 1966, Jan-25, Volume: 115, Issue:1

    Topics: Acetoacetates; Adenine Nucleotides; Adenosine Triphosphate; Animals; Caproates; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Dietary Fats; Hexosephosphates; Hydroxybutyrates; Lactates; Liver; Liver Glycogen; Malates; NAD; Oxaloacetates; Phosphates; Pyruvates; Rats; Starvation

1966
Enzyme histochemistry in experimental diabetes mellitus. 3. Findings on several enzyme activities in pancreatic islet cells of chronic diabetic rabbits.
    Endocrinologia japonica, 1966, Volume: 13, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Histocytochemistry; Indicators and Reagents; Islets of Langerhans; L-Lactate Dehydrogenase; NAD; Oxidoreductases; Phosphoric Monoester Hydrolases; Rabbits; Succinate Dehydrogenase

1966
The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver.
    The Biochemical journal, 1967, Volume: 103, Issue:2

    Topics: Ammonium Chloride; Animals; Centrifugation; Chemical Phenomena; Chemistry; Cytoplasm; Diabetes Mellitus, Experimental; Glutamate Dehydrogenase; Hydroxybutyrate Dehydrogenase; Ketone Bodies; Kinetics; L-Lactate Dehydrogenase; Lactates; Liver; Male; Mitochondria; NAD; Oxaloacetates; Oxidation-Reduction; Pyruvates; Rats; Spectrophotometry; Starvation

1967
Concentrations of pyruvate kinase and lactate dehydrogenase in the kidney of the alloxan diabetic rat.
    Nature, 1967, Aug-26, Volume: 215, Issue:5104

    Topics: Animals; Diabetes Mellitus, Experimental; Female; Kidney; L-Lactate Dehydrogenase; Liver; NAD; Pyruvate Kinase; Pyruvates; Rats

1967
Role of the redox state of nicotinamide adenine dinucleotides in the regulation of metabolic processes.
    National Cancer Institute monograph, 1967, Volume: 27

    Topics: Acetoacetates; Animals; Cytoplasm; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Glutamate Dehydrogenase; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Mitochondria, Liver; NAD; Oxidation-Reduction; Pyruvates; Rats; Starvation; Succinates

1967
Studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD) in mammals and its regulatory mechanism. I.
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:11

    Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cats; Diabetes Mellitus, Experimental; Glutarates; Kidney; Liver; Liver Neoplasms; Mice; NAD; Rats; Tryptophan

1967
Streptozotocin: depression of mouse liver pyridine nucleotides.
    Cancer research, 1968, Volume: 28, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Diabetes Mellitus, Experimental; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Mice; NAD; Nitroso Compounds; Streptomyces

1968
The redox state of nicotinamide adenine dinucleotide in the cytoplasm and mitochondria of rat liver.
    Advances in enzyme regulation, 1967, Volume: 5

    Topics: Ammonium Chloride; Animals; Cytoplasm; Diabetes Mellitus, Experimental; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Hydroxybutyrate Dehydrogenase; L-Lactate Dehydrogenase; Liver; Mitochondria, Liver; NAD; Oxaloacetates; Oxidation-Reduction; Rats; Starvation

1967
Ketogenesis in vitro.
    Biochimica et biophysica acta, 1969, Feb-18, Volume: 177, Issue:1

    Topics: Acetoacetates; Animals; Coenzyme A; Cyanides; Diabetes Mellitus; Diabetes Mellitus, Experimental; Hydroxybutyrates; In Vitro Techniques; Ketone Bodies; Liver; Male; NAD; Organ Size; Pancreas; Pancreatectomy; Rats; Starvation

1969
Effects of fasting and diabetes on fatty acid synthesis by heart mitochondria.
    The American journal of physiology, 1969, Volume: 217, Issue:4

    Topics: Acetates; Animals; Carbon Isotopes; Diabetes Mellitus, Experimental; Fasting; Fatty Acids; Glycogen; Ligases; Microsomes, Liver; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; NAD; Rabbits

1969
Effects of streptozotocin on carbohydrate and lipid metabolism in the rat.
    Endocrinology, 1971, Volume: 89, Issue:3

    Topics: Acetoacetates; Animals; Antibiotics, Antineoplastic; Blood Glucose; Carbamates; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucosamine; Glucose; Glyceric Acids; Hydroxybutyrates; Hyperglycemia; Hypolipidemic Agents; Ketoglutaric Acids; Ketone Bodies; Lactates; Lipid Metabolism; Liver; Liver Glycogen; Male; NAD; Niacinamide; Nitroso Compounds; Pyrazoles; Pyruvates; Rats; Triglycerides

1971
Streptozotocin diabetes. Correlation with extent of depression of pancreatic islet nicotinamide adenine dinucleotide.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:3

    Topics: Alloxan; Animals; Carbon Radioisotopes; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Islets of Langerhans; Male; Mice; NAD; Nitrosourea Compounds; Streptozocin; Time Factors

1974
The metabolic transformation of phenylbutazone in the alloxan diabetic rat.
    Comparative and general pharmacology, 1974, Volume: 5, Issue:1

    Topics: Alkaline Phosphatase; Animals; Biotransformation; Diabetes Mellitus, Experimental; In Vitro Techniques; Insulin; Liver; Male; Microsomes, Liver; NAD; Phenylbutazone; Proteins; Rats

1974
The activities of nicotinamide mononucleotide adenylyltransferase and of nicotinamide-adenine dinucleotide kinase in the livers of rats subjected to different hormonal treatments.
    The Biochemical journal, 1965, Volume: 96, Issue:2

    Topics: Adenine Nucleotides; Adrenalectomy; Animals; Diabetes Mellitus, Experimental; Glucagon; Growth Hormone; Liver; N-Glycosyl Hydrolases; NAD; NADP; Nucleotidyltransferases; Phosphotransferases; Rats; Thyroxine

1965
Nicotinamide coenzyme concentrations in livers of normal, starved and alloxan-diabetic rats.
    The Biochemical journal, 1964, Volume: 93, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry; Diabetes Mellitus, Experimental; Fluorometry; Liver; NAD; NADP; Rats; Starvation

1964
The metabolism of the retina of the normal and alloxan diabetic rat. The levels of oxidised and reduced pyridine nucleotides and the oxidation of the carbon-1 and carbon-6 of glucose.
    Vision research, 1966, Volume: 5, Issue:5

    Topics: Animals; Carbon; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Female; Glucose; In Vitro Techniques; Male; NAD; NADP; Oxidation-Reduction; Rats; Retina

1966
Studies of the metabolic effects of acute insulin deficiency. II. Changes in hepatic glycolytic and krebs-cycle intermediates and pyridine nucleotides.
    Diabetes, 1966, Volume: 15, Issue:7

    Topics: Animals; Blood Glucose; Citric Acid Cycle; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids; Glycolysis; Guinea Pigs; Hexosephosphates; In Vitro Techniques; Insulin; Insulin Antibodies; Lactates; Lipids; Liver Glycogen; NAD; NADP; Phosphates; Pyruvates; Rats

1966
The sorbitol pathway. Enzyme localization and content in normal and diabetic nerve and cord.
    Diabetes, 1968, Volume: 17, Issue:5

    Topics: Animals; Axons; Blood Glucose; Cauda Equina; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Glucose; Glyceraldehyde; Glycosuria; Hyperglycemia; Male; NAD; NADP; Nerve Regeneration; Oxidoreductases; Rabbits; Rats; Schwann Cells; Sciatic Nerve; Sorbitol; Spinal Cord

1968