Compounds > nad
Page last updated: 2024-08-17

nad and Allergic Encephalomyelitis

nad has been researched along with Allergic Encephalomyelitis in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's2 (11.76)18.2507
2000's3 (17.65)29.6817
2010's6 (35.29)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Guo, L; Li, B; Song, X; Sun, P; Tan, G; Wang, J; Zhang, N1
Ejtemaei-Mehr, S; Ghahremani, MH; Ghanbari, A; Ghazi-Khansari, M; Guillemin, GJ; Jand, Y1
Gai, XL; Guo, L; Li, B; Quan, MY; Tan, GJ; Wang, JL; Wang, JQ; Xing, JN; Zhang, N1
Adossa, N; Almeida, L; Berod, L; Blazar, BR; Carriche, GM; Castro, CN; Dennerlein, S; Dhillon-LaBrooy, A; Guderian, M; Hesse, C; Kalesse, M; Lambrecht, BN; Lippens, S; Moita, LF; Müller, R; Schauser, L; Sparwasser, T1
Guo, L; Li, B; Liu, L; Ma, T; Wang, X; Zhang, L1
Ahmad, V; Bever, CT; Chandrasekaran, K; Judge, SI; Makar, TK; Nagalla, NK; Nimmagadda, VK; Royal, W; Russell, JW; Talat, S; Trisler, D; Vattikunta, NR1
Arredouani, MS; Biefer, HR; Camacho, V; de la Fuente, MA; Edtinger, K; El Fatimy, R; ElKhal, A; Ghiran, I; Kissick, HT; Krenzien, F; Kuo, WP; Li, S; Quante, M; Smith, BD; Tigges, JC; Toxavidis, V; Trachtenberg, AJ; Tullius, SG; Uehara, H; Vasudevan, A; Yang, X1
Chin, J; Ciric, B; Curtis, M; Li, X; Ma, CG; Rostami, A; Yan, Y; Zhang, GX; Zhang, Y1
Bever, CT; Chandrasekaran, K; Makar, TK; Nimmagadda, VK; Ray, J; Russell, JW; Sagi, AR1
Bian, G; Guo, L; Kong, P; Sun, H; Sun, Y; Sun, Z; Wang, J; Zhao, C1
Ballestrero, A; Benvenuto, F; Bruzzone, S; Cea, M; D'Urso, A; Ferrando, T; Fruscione, F; Garuti, A; Moran, E; Morando, S; Mostoslavsky, R; Nencioni, A; Patrone, F; Poggi, A; Selmo, M; Soncini, D; Sordat, B; Uccelli, A; Zoppoli, G1
Barkhouse, DA; Castegna, A; Curtis, MT; Fabis-Pedrini, MJ; Hooper, DC; Kean, RB; Palmieri, F; Palmieri, L; Porcelli, V; Spera, I1
Chiarugi, A1
Chitnis, T; He, Z; Hurrell, JM; Kaneko, M; Kaneko, S; Khoury, SJ; Wang, J; Yiu, G1
Hartung, HP; Jung, S; Künzig, H; Reichmann, H; Toyka, KV; Zielasek, J1
Cockle, S; Robbinson, D; Singh, B; Strejan, GH1
Balasubramanian, AS; Bishayee, S1

Reviews

1 review(s) available for nad and Allergic Encephalomyelitis

ArticleYear
SIRT1 and NAD+ precursors: Therapeutic targets in multiple sclerosis a review.
    Journal of neuroimmunology, 2017, 03-15, Volume: 304

    Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Humans; Immunosuppressive Agents; Multiple Sclerosis; NAD; Sirtuin 1

2017

Other Studies

16 other study(ies) available for nad and Allergic Encephalomyelitis

ArticleYear
NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway.
    Aging, 2021, 12-20, Volume: 13, Issue:24

    Topics: Animals; Autophagy; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Mice; Mice, Inbred C57BL; NAD; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirtuin 1; Thymus Gland; TOR Serine-Threonine Kinases

2021
Melatonin ameliorates disease severity in a mouse model of multiple sclerosis by modulating the kynurenine pathway.
    Scientific reports, 2022, 09-24, Volume: 12, Issue:1

    Topics: Animals; Biological Factors; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Melatonin; Mice; Mice, Inbred C57BL; Multiple Sclerosis; NAD; Nicotinamide N-Methyltransferase; Receptors, Aryl Hydrocarbon; RNA, Messenger; Severity of Illness Index; Tryptophan

2022
NAD+ attenuates experimental autoimmune encephalomyelitis through induction of CD11b+ gr-1+ myeloid-derived suppressor cells.
    Bioscience reports, 2020, 04-30, Volume: 40, Issue:4

    Topics: Animals; CD11b Antigen; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Mice; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Myeloid-Derived Suppressor Cells; NAD; Peptide Fragments; Phosphorylation; Receptors, Chemokine; STAT6 Transcription Factor

2020
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis.
    Immunity, 2021, 01-12, Volume: 54, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Autoimmunity; Cell Differentiation; Encephalomyelitis, Autoimmune, Experimental; Humans; Linezolid; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Proteins; Molecular Targeted Therapy; Multiple Sclerosis; NAD; Oxidative Phosphorylation; Peptide Elongation Factor G; Peptides, Cyclic; Ribosomes; Th17 Cells

2021
Nicotinamide adenine dinucleotide treatment alleviates the symptoms of experimental autoimmune encephalomyelitis by activating autophagy and inhibiting the NLRP3 inflammasome.
    International immunopharmacology, 2021, Volume: 90

    Topics: Animals; Autophagy; Autophagy-Related Proteins; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammasomes; Inflammation Mediators; Mice, Inbred C57BL; Microglia; NAD; Neurons; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction; Spinal Cord

2021
Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets.
    Journal of immunology (Baltimore, Md. : 1950), 2013, May-01, Volume: 190, Issue:9

    Topics: Animals; Apoptosis; Axons; Brain-Derived Neurotrophic Factor; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; NAD; Neurons; Neuroprotective Agents; Resveratrol; Sirtuin 1; Spinal Cord; Stilbenes

2013
NAD+ protects against EAE by regulating CD4+ T-cell differentiation.
    Nature communications, 2014, Oct-07, Volume: 5

    Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Homeostasis; Mice; Multiple Sclerosis; Myelin Sheath; NAD; Regeneration; Tryptophan Hydroxylase

2014
LINGO-1-Fc-Transduced Neural Stem Cells Are Effective Therapy for Chronic Stage Experimental Autoimmune Encephalomyelitis.
    Molecular neurobiology, 2017, Volume: 54, Issue:6

    Topics: Animals; Autocrine Communication; Axons; Cell Count; Cell Differentiation; Chronic Disease; Encephalomyelitis, Autoimmune, Experimental; Female; Membrane Proteins; Mice, Inbred C57BL; Myelin Basic Protein; NAD; Neural Stem Cells; Neurons; Oligodendroglia; Paracrine Communication; Receptors, Fc; Recovery of Function; Remyelination; Sirtuin 2; Stem Cell Transplantation; Transduction, Genetic

2017
Treatment with NAD(+) inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice.
    International immunopharmacology, 2016, Volume: 39

    Topics: AMP-Activated Protein Kinases; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Inflammation; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; NAD; Signal Transduction; Sirtuin 1; Th1 Cells; Th17 Cells

2016
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
    PloS one, 2009, Nov-19, Volume: 4, Issue:11

    Topics: Acrylamides; Adenosine Triphosphate; Animals; Autophagy; Cell Proliferation; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Interferon-gamma; Jurkat Cells; Lymphocyte Activation; Membrane Potentials; Mice; Mice, Inbred C57BL; Myelin Sheath; NAD; Nicotinamide Phosphoribosyltransferase; Piperidines; Poly(ADP-ribose) Polymerases; T-Lymphocytes; Tumor Necrosis Factor-alpha

2009
Oxidative stress and reduced glutamine synthetase activity in the absence of inflammation in the cortex of mice with experimental allergic encephalomyelitis.
    Neuroscience, 2011, Jun-30, Volume: 185

    Topics: Analysis of Variance; Animals; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Encephalitis; Encephalomyelitis, Autoimmune, Experimental; Female; Glutamate-Ammonia Ligase; Glutamic Acid; Glutamine; Glutathione; Glutathione Disulfide; Guinea Pigs; Mice; Myelin Basic Protein; NAD; NADP; Nitric Oxide Synthase Type II; Oxidative Stress; Tandem Mass Spectrometry

2011
Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats.
    British journal of pharmacology, 2002, Volume: 137, Issue:6

    Topics: Adenosine Triphosphate; Animals; Benzamides; Benzoic Acid; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Interferon-gamma; Interleukin-2; Lymph Nodes; Lymphocytes; NAD; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Lew; RNA, Messenger; Spinal Cord; Time Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha

2002
Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Sep-20, Volume: 26, Issue:38

    Topics: Animals; Axons; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Multiple Sclerosis; NAD; Nerve Degeneration; Neuroprotective Agents; Rats; Wallerian Degeneration

2006
Inhibition of brain macrophage/microglial respiratory chain enzyme activity in experimental autoimmune encephalomyelitis of the Lewis rat.
    Neuroscience letters, 1995, Jan-23, Volume: 184, Issue:2

    Topics: Animals; Animals, Newborn; Brain; Electron Transport Complex IV; Encephalomyelitis, Autoimmune, Experimental; Macrophages; Male; Microglia; Mitochondria; NAD; NADH Dehydrogenase; Rats; Rats, Inbred Lew; Spinal Cord; Succinate Cytochrome c Oxidoreductase; Succinate Dehydrogenase

1995
Native, but not genetically inactivated, pertussis toxin protects mice against experimental allergic encephalomyelitis.
    Cellular immunology, 1996, Mar-15, Volume: 168, Issue:2

    Topics: Allosteric Site; Amino Acid Sequence; Animals; Autoimmune Diseases; Binding Sites; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; Immunosuppressive Agents; Immunotherapy, Adoptive; Ionophores; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred Strains; Mitogens; Molecular Sequence Data; Muromonab-CD3; Mutagenesis, Site-Directed; Myelin Proteins; Myelin Proteolipid Protein; NAD; Peptide Fragments; Pertussis Toxin; Poly(ADP-ribose) Polymerases; Signal Transduction; Tuberculin; Virulence Factors, Bordetella

1996
Lipid peroxide formation in rat brain.
    Journal of neurochemistry, 1971, Volume: 18, Issue:6

    Topics: Aging; Animals; Ascorbic Acid; Brain; Brain Chemistry; Cell Nucleus; Edetic Acid; Encephalomyelitis, Autoimmune, Experimental; Hot Temperature; Hydrogen-Ion Concentration; Iron; Lipid Metabolism; Lipids; Metals; Microsomes; Mitochondria; Myelin Sheath; NAD; NADP; Peroxides; Proteins; Rats; Sulfhydryl Compounds; Surface-Active Agents; Synaptic Vesicles

1971