Page last updated: 2024-08-17

nad and African Sleeping Sickness

nad has been researched along with African Sleeping Sickness in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hall, BS; Wilkinson, SR1
Callens, M; Hannaert, V; Herdewijn, P; Hol, WG; Michels, PA; Opperdoes, FR; Van Aerschot, A; Van Calenbergh, S; Verlinde, CL1
Zubrzycki, IZ1

Other Studies

3 other study(ies) available for nad and African Sleeping Sickness

ArticleYear
Activation of benznidazole by trypanosomal type I nitroreductases results in glyoxal formation.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1

    Topics: Biotransformation; Chagas Disease; Chromatography, Liquid; DNA Damage; Glyoxal; Guanosine; Humans; Hydroxylamine; Imidazoles; Kinetics; Mass Spectrometry; NAD; Nitroimidazoles; Nitroreductases; Prodrugs; Protozoan Proteins; Spectrophotometry; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis, African

2012
Selective inhibition of trypanosomal glyceraldehyde-3-phosphate dehydrogenase by protein structure-based design: toward new drugs for the treatment of sleeping sickness.
    Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21

    Topics: Adenosine; Animals; Binding Sites; Deoxyadenosines; Drug Design; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Bonding; Leishmania mexicana; Molecular Structure; NAD; Protein Conformation; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosomiasis, African

1994
Homology modeling and molecular dynamics study of NAD-dependent glycerol-3-phosphate dehydrogenase from Trypanosoma brucei rhodesiense, a potential target enzyme for anti-sleeping sickness drug development.
    Biophysical journal, 2002, Volume: 82, Issue:6

    Topics: Amino Acid Sequence; Animals; Binding Sites; Biophysical Phenomena; Biophysics; Drug Design; Enzyme Stability; Glycerolphosphate Dehydrogenase; Humans; Leishmania mexicana; Models, Molecular; Molecular Sequence Data; NAD; Protein Conformation; Sequence Homology, Amino Acid; Species Specificity; Thermodynamics; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2002