Page last updated: 2024-08-17

nad and Acute Brain Injuries

nad has been researched along with Acute Brain Injuries in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's5 (17.86)18.2507
2000's8 (28.57)29.6817
2010's10 (35.71)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Cai, YN; Cheng, HB; Gao, GD; Gao, L; Hu, Q; Luo, JN; Wang, XL; Wu, X; Wu, Y; Wu, YX; Yu, JG; Zhang, YZ; Zhu, G1
Akaike, T; Atochin, DN; Batten, A; Bloch, DB; Corman, B; Flicker, DR; Grange, RMH; Hanaoka, K; Hindle, AG; Hirai, S; Ichinose, F; Ida, T; Ihara, H; Ikeda, T; Kai, S; Kevil, CG; Li, R; Magliocca, A; Marutani, E; Matsunaga, T; Miyazaki, Y; Mori, N; Morita, M; Motohashi, H; Nagashima, F; Nakagawa, A; Nishida, M; Olenchock, BA; Shen, X; Tanaka, T; Traeger, L; Xian, M; Yamazaki, Y1
Guan, YF; Kong, YY; Li, GQ; Miao, CY; Wang, P; Wei, CC1
Kristian, T; Owens, K; Park, JH; Schuh, R1
Bar-Or, D; Bar-Or, R; Brody, EN; Rael, LT1
Cao, W; Chen, H; Ding, X; Hong, Y; Li, J; Ma, Y; Nie, H; Qu, X; Wang, B; Wang, C; Xu, Y; Yin, SK; Ying, W; Zhang, J; Zhang, M1
Jiang, WX; Lu, JT; Lu, YB; Tang, C; Wei, EQ; Wu, M; Zhang, WP; Zhang, XQ1
Amaral, AU; de Souza, DO; Goodman, SI; Leipnitz, G; Rodrigues, MD; Seminotti, B; Wajner, M; Woontner, M1
Kristian, T; Long, A; Owens, K; Park, JH1
Manaenko, A; Sozen, T; Tang, J; Tsuchiyama, R; Zhang, JH1
Amorini, AM; Barrios, L; Di Pietro, V; Marmarou, A; Marmarou, CR; Pascual, JM; Prieto, R; Tavazzi, B; Taya, K1
Halámek, J; Katz, E; Valdés-Ramírez, G; Wang, J; Windmiller, JR; Zhou, M; Zhou, N1
Choi, BY; Sohn, M; Suh, SW; Swanson, RA; Won, SJ; Ying, W; Yoo, BH1
Clark, RS; Dixon, CE; Jenkins, LW; Kochanek, PM; Melick, J; Satchell, MA; Szabó, C; Zhang, X1
SPECTOR, RG1
OSTERBERG, KA; WATTENBERG, LW1
Cosi, C; Guerin, K; Koek, W; Marien, M; Rollet, K1
Amorini, AM; Cimatti, M; Delfini, R; Lazzarino, G; Marmarou, A; Signoretti, S; Tavazzi, B; Vagnozzi, R1
Ho, YS; Lee, CP; Shie, FS; Xiong, Y; Zhang, J1
Clark, RS; Dixon, CE; Jenkins, LW; Nathaniel, PD; Szabó, C; Vagni, VA1
Ying, W1
Chen, Y; Clark, RS; Guo, F; Jenkins, LW; Kochanek, PM; Lai, Y; Nathaniel, PD; Szabó, C; Watkins, SC1
Belkin, M; Schwartz, M; Yoles, E1
Doron, A; Mayevsky, A; Rogatsky, G; Zarchin, N1
LaPlaca, MC; McIntosh, TK; Pieper, AA; Raghupathi, R; Saatman, KE; Snyder, SH; Verma, A1
Doron, A; Manor, T; Mayevsky, A; Meilin, S; Ornstein, E; Ouaknine, GE1
Manor, T; Mayevsky, A; Meilin, S; Mendelman, A; Sonn, J; Zarchin, N1
Duncan, P; Evans, S; Gehrt, M; Robinson, N; Sancres, A1

Reviews

4 review(s) available for nad and Acute Brain Injuries

ArticleYear
Mitochondrial dysfunction and NAD(+) metabolism alterations in the pathophysiology of acute brain injury.
    Translational stroke research, 2013, Volume: 4, Issue:6

    Topics: ADP-ribosyl Cyclase 1; Agouti-Related Protein; Animals; Brain Injuries; Humans; Mice; Mitochondria; NAD; Poly(ADP-ribose) Polymerases

2013
Oxidative stress in severe acute illness.
    Redox biology, 2015, Volume: 4

    Topics: Acute Disease; Antioxidants; Brain Injuries; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Multiple Trauma; Myocardial Infarction; NAD; Oxidative Stress; Reactive Oxygen Species; Sepsis; Stroke; Superoxide Dismutase; Thioredoxins

2015
NAD⁺/NADH metabolism and NAD⁺-dependent enzymes in cell death and ischemic brain injury: current advances and therapeutic implications.
    Current medicinal chemistry, 2015, Volume: 22, Issue:10

    Topics: ADP-ribosyl Cyclase 1; Animals; Brain Injuries; Brain Ischemia; Cell Death; Humans; NAD; Poly(ADP-ribose) Polymerases; Sirtuins

2015
NAD+ and NADH in ischemic brain injury.
    Frontiers in bioscience : a journal and virtual library, 2008, Jan-01, Volume: 13

    Topics: Animals; Apoptosis; Brain; Brain Injuries; Brain Ischemia; Cell Death; Humans; Ischemia; Ischemic Preconditioning; Models, Biological; NAD; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases

2008

Other Studies

24 other study(ies) available for nad and Acute Brain Injuries

ArticleYear
P7C3-A20 Attenuates Microglial Inflammation and Brain Injury after ICH through Activating the NAD
    Oxidative medicine and cellular longevity, 2023, Volume: 2023

    Topics: Animals; Brain Injuries; Cerebral Hemorrhage; Inflammation; Mice; Microglia; NAD; Sirtuin 3

2023
Sulfide catabolism ameliorates hypoxic brain injury.
    Nature communications, 2021, 05-25, Volume: 12, Issue:1

    Topics: Animals; Brain; Brain Injuries; Cells, Cultured; Female; Hydrogen Sulfide; Hypoxia; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mitochondria; NAD; Quinone Reductases; Rats, Sprague-Dawley; RNA Interference

2021
Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway.
    Scientific reports, 2017, 04-06, Volume: 7, Issue:1

    Topics: Animals; Biomarkers; Brain Injuries; Cell Death; Cerebral Hemorrhage; Disease Models, Animal; Heme Oxygenase-1; Immunohistochemistry; Inflammation Mediators; Mice; Microglia; NAD; Neuroprotection; Neutrophil Infiltration; NF-E2-Related Factor 2; Nicotinamide Mononucleotide; Oxidative Stress; Protective Agents; Signal Transduction; Time Factors

2017
NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.
    Neuroscience, 2015, Apr-16, Volume: 291

    Topics: Acrylamides; Acute Disease; Animals; Astrocytes; Brain; Brain Injuries; Calcium-Binding Proteins; Cell Count; Chronic Disease; Cold Temperature; Cytokines; Disease Models, Animal; Macrophages; Male; Mice, Inbred BALB C; Microfilament Proteins; Microglia; NAD; Neurons; Neuroprotective Agents; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Piperidines

2015
Experimental evidence that overexpression of NR2B glutamate receptor subunit is associated with brain vacuolation in adult glutaryl-CoA dehydrogenase deficient mice: A potential role for glutamatergic-induced excitotoxicity in GA I neuropathology.
    Journal of the neurological sciences, 2015, Dec-15, Volume: 359, Issue:1-2

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic; Brain Injuries; Catalase; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Fluoresceins; Gene Expression Regulation; Glucosephosphate Dehydrogenase; Glutaryl-CoA Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Malondialdehyde; Mice; Mice, Transgenic; NAD; Receptors, N-Methyl-D-Aspartate; Sulfhydryl Compounds; Superoxide Dismutase

2015
Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.
    Neurobiology of disease, 2016, Volume: 95

    Topics: Animals; Brain Injuries; Brain Ischemia; Cell Death; Disease Models, Animal; Hippocampus; Male; Mice, Inbred C57BL; NAD; Niacinamide; Nicotinamide Mononucleotide

2016
The effects of nicotinamide adenine dinucleotide on intracerebral hemorrhage-induced brain injury in mice.
    Neurological research, 2009, Volume: 31, Issue:2

    Topics: Administration, Intranasal; Analysis of Variance; Animals; Brain Edema; Brain Injuries; Cerebral Hemorrhage; Collagenases; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; NAD; Neurologic Examination; Neuroprotective Agents

2009
Brain energy depletion in a rodent model of diffuse traumatic brain injury is not prevented with administration of sodium lactate.
    Brain research, 2011, Aug-02, Volume: 1404

    Topics: Adenosine Triphosphate; Animals; Ascorbic Acid; Aspartic Acid; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Brain Injuries; Cerebral Cortex; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Glutathione; Male; Models, Biological; NAD; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sodium Lactate

2011
Enzyme-based NAND gate for rapid electrochemical screening of traumatic brain injury in serum.
    Analytica chimica acta, 2011, Oct-03, Volume: 703, Issue:1

    Topics: Biocatalysis; Biomarkers; Brain Injuries; Buffers; Electrochemistry; Electrodes; Glutamic Acid; Humans; Hydrogen-Ion Concentration; L-Lactate Dehydrogenase; Methylene Blue; NAD; Time Factors

2011
Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotide.
    Journal of neurotrauma, 2012, May-01, Volume: 29, Issue:7

    Topics: Administration, Intranasal; Animals; Brain Damage, Chronic; Brain Injuries; Cell Death; Male; Microglia; NAD; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome

2012
A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma.
    Journal of neurochemistry, 2003, Volume: 85, Issue:3

    Topics: 14-3-3 Proteins; Adenosine Diphosphate Ribose; Animals; Brain; Brain Injuries; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Enzyme Inhibitors; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Proteins; Tyrosine 3-Monooxygenase

2003
Selective changes in dehydrogenase enzymes and pyridine nucleotides in rat brain in anoxic-ischaemic encephalopathy.
    British journal of experimental pathology, 1963, Volume: 44

    Topics: Brain; Brain Injuries; Electron Transport Complex II; Hypoxia-Ischemia, Brain; L-Lactate Dehydrogenase; NAD; NADP; Nucleotides; Oxidoreductases; Pyridines; Succinate Dehydrogenase

1963
ENZYME INDUCTION IN IMMATURE GLIA.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: Animals; Animals, Newborn; Brain Chemistry; Brain Injuries; Dihydrolipoamide Dehydrogenase; Enzyme Induction; Histocytochemistry; NAD; NADP; Neuroglia; Rats; Research

1965
The PARP inhibitor benzamide protects against kainate and NMDA but not AMPA lesioning of the mouse striatum in vivo.
    Brain research, 2004, Jan-16, Volume: 996, Issue:1

    Topics: Adenosine Triphosphate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzamides; Brain Injuries; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; NAD; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Time Factors

2004
Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats.
    Neurosurgery, 2005, Volume: 56, Issue:3

    Topics: Animals; Ascorbic Acid; Aspartic Acid; Biomarkers; Brain; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; Energy Metabolism; Head Injuries, Closed; Hypotension; Hypoxia; Male; Malondialdehyde; NAD; NADP; Nucleosides; Oxidative Stress; Phosphates; Purines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2005
Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase.
    Journal of neurochemistry, 2005, Volume: 95, Issue:3

    Topics: Animals; Brain; Brain Injuries; Calcium; Chelating Agents; Egtazic Acid; Female; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, Transgenic; Mitochondria; NAD; Oxidative Phosphorylation; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1

2005
Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice.
    Journal of neurotrauma, 2007, Volume: 24, Issue:8

    Topics: Animals; Brain Injuries; Indoles; Injections, Intralesional; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; NAD; Poly(ADP-ribose) Polymerase Inhibitors

2007
Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury.
    Journal of neurochemistry, 2008, Volume: 104, Issue:6

    Topics: Animals; Brain; Brain Injuries; Cell Respiration; Electron Transport; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; NAD; Nitrogen; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley

2008
HU-211, a nonpsychotropic cannabinoid, produces short- and long-term neuroprotection after optic nerve axotomy.
    Journal of neurotrauma, 1996, Volume: 13, Issue:1

    Topics: Action Potentials; Animals; Axons; Brain Injuries; Dose-Response Relationship, Drug; Dronabinol; Drug Administration Schedule; Electrophysiology; Energy Metabolism; Evoked Potentials, Visual; Male; NAD; Nerve Crush; Neuroprotective Agents; Optic Nerve; Optic Nerve Injuries; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Time Factors

1996
Continuous multiparametric monitoring of brain activities following fluid-percussion injury in rats: preliminary results.
    Journal of basic and clinical physiology and pharmacology, 1996, Volume: 7, Issue:1

    Topics: Brain Injuries; Cortical Spreading Depression; Hyperbaric Oxygenation; Intracranial Pressure; Laser-Doppler Flowmetry; NAD; Seizures

1996
Temporal patterns of poly(ADP-ribose) polymerase activation in the cortex following experimental brain injury in the rat.
    Journal of neurochemistry, 1999, Volume: 73, Issue:1

    Topics: Animals; Apoptosis; Brain Injuries; Cerebral Cortex; DNA Damage; DNA Fragmentation; Enzyme Activation; Kinetics; Male; NAD; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley

1999
Brain viability and function analyzer: multiparametric real-time monitoring in neurosurgical patients.
    Acta neurochirurgica. Supplement, 1999, Volume: 75

    Topics: Body Temperature; Brain; Brain Injuries; Carbon Dioxide; Computer Systems; Electric Stimulation; Equipment Design; Extracellular Space; Fiber Optic Technology; Humans; Monitoring, Physiologic; NAD; Neural Analyzers; Oxidation-Reduction; Potassium; Time Factors

1999
Metabolic and hemodynamic oscillations monitored optically in the brain exposed to various pathological states.
    Advances in experimental medicine and biology, 1999, Volume: 471

    Topics: Animals; Brain Injuries; Brain Ischemia; Cerebral Cortex; Hemodynamics; Humans; NAD; Rats

1999
Histochemistry of trauma after electrode implantation and stimulation in the hippocampus.
    Archives of neurology, 1975, Volume: 32, Issue:2

    Topics: Acetylcholinesterase; Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Brain Injuries; Dihydrolipoamide Dehydrogenase; Electric Stimulation; Electrodes, Implanted; Glucosephosphate Dehydrogenase; Glycerolphosphate Dehydrogenase; Hippocampus; L-Lactate Dehydrogenase; Male; Monoamine Oxidase; NAD; Nucleotidases; Rats; Stereotaxic Techniques; Time Factors

1975
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