nabumetone has been researched along with Spondylitis, Ankylosing in 5 studies
Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
Spondylitis, Ankylosing: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nabumetone is a new non-steroidal anti-inflammatory drug advocated for use in the symptomatic treatment of rheumatic and inflammatory conditions." | 3.76 | Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases. ( Friedel, HA; Todd, PA, 1988) |
| "Forty-two patients with ankylosing spondylitis were entered into a double-blind study to compare treatment with indomethacin and a new non-steroidal anti-inflammatory drug, nabumetone." | 2.67 | A comparative study of nabumetone and indomethacin in ankylosing spondylitis. ( Palferman, TG; Webley, M, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, W | 1 |
| Wang, YM | 1 |
| Li, SL | 1 |
| Yan, M | 1 |
| Li, D | 1 |
| Chen, BY | 1 |
| Cheng, NN | 1 |
| Schwartzenberg, JM | 1 |
| Smith, DD | 1 |
| Lindsley, HB | 1 |
| Palferman, TG | 1 |
| Webley, M | 1 |
| Friedel, HA | 1 |
| Todd, PA | 1 |
| Jenner, PN | 1 |
| Johnson, ES | 1 |
1 review available for nabumetone and Spondylitis, Ankylosing
| Article | Year |
|---|---|
Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; | 1988 |
3 trials available for nabumetone and Spondylitis, Ankylosing
| Article | Year |
|---|---|
A comparative study of nabumetone and indomethacin in ankylosing spondylitis.
Topics: Adult; Aged; Butanones; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Nabume | 1991 |
Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; | 1988 |
Review of the experience with nabumetone in clinical trials outside of the United States.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Athletic Injuries; Butanones; | 1987 |
2 other studies available for nabumetone and Spondylitis, Ankylosing
| Article | Year |
|---|---|
Risk factors of adverse drug reaction from non-steroidal anti-inflammatory drugs in Shanghai patients with arthropathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu | 2004 |
Bacillus Calmette-Guérin associated arthropathy mimicking undifferentiated spondyloarthropathy.
Topics: Arthritis, Reactive; BCG Vaccine; Butanones; Carcinoma, Transitional Cell; Cytokines; Diagnosis, Dif | 1999 |