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nabumetone and Spondylitis, Ankylosing

nabumetone has been researched along with Spondylitis, Ankylosing in 5 studies

Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

Spondylitis, Ankylosing: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.

Research Excerpts

ExcerptRelevanceReference
"Nabumetone is a new non-steroidal anti-inflammatory drug advocated for use in the symptomatic treatment of rheumatic and inflammatory conditions."3.76Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases. ( Friedel, HA; Todd, PA, 1988)
"Forty-two patients with ankylosing spondylitis were entered into a double-blind study to compare treatment with indomethacin and a new non-steroidal anti-inflammatory drug, nabumetone."2.67A comparative study of nabumetone and indomethacin in ankylosing spondylitis. ( Palferman, TG; Webley, M, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shi, W1
Wang, YM1
Li, SL1
Yan, M1
Li, D1
Chen, BY1
Cheng, NN1
Schwartzenberg, JM1
Smith, DD1
Lindsley, HB1
Palferman, TG1
Webley, M1
Friedel, HA1
Todd, PA1
Jenner, PN1
Johnson, ES1

Reviews

1 review available for nabumetone and Spondylitis, Ankylosing

ArticleYear
Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases.
    Drugs, 1988, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid;

1988

Trials

3 trials available for nabumetone and Spondylitis, Ankylosing

ArticleYear
A comparative study of nabumetone and indomethacin in ankylosing spondylitis.
    European journal of rheumatology and inflammation, 1991, Volume: 11, Issue:2

    Topics: Adult; Aged; Butanones; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Nabume

1991
Nabumetone. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in rheumatic diseases.
    Drugs, 1988, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid;

1988
Review of the experience with nabumetone in clinical trials outside of the United States.
    The American journal of medicine, 1987, Oct-30, Volume: 83, Issue:4B

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Athletic Injuries; Butanones;

1987

Other Studies

2 other studies available for nabumetone and Spondylitis, Ankylosing

ArticleYear
Risk factors of adverse drug reaction from non-steroidal anti-inflammatory drugs in Shanghai patients with arthropathy.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu

2004
Bacillus Calmette-Guérin associated arthropathy mimicking undifferentiated spondyloarthropathy.
    The Journal of rheumatology, 1999, Volume: 26, Issue:4

    Topics: Arthritis, Reactive; BCG Vaccine; Butanones; Carcinoma, Transitional Cell; Cytokines; Diagnosis, Dif

1999