Page last updated: 2024-10-31

nabumetone and Rheumatism

nabumetone has been researched along with Rheumatism in 11 studies

Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

Research Excerpts

ExcerptRelevanceReference
"Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used to treat rheumatic and inflammatory conditions."5.29Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases. ( Buckley, MM; Friedel, HA; Langtry, HD, 1993)
"We evaluated the clinical efficacy and the tolerance of Nabumetone (N), in comparison with a pool of non-steroidal anti-inflammatory drugs (NSAIDs), in a cohort of patients affected by rheumatoid arthritis, osteoarthritis, non-articular rheumatisms and primary fibromyalgic syndrome."5.08Clinical efficacy and tolerance of nabumetone in articular and non-articular rheumatic disorders: personal experience during 12 weeks of treatment. ( Allegra, A; Coaccioli, S; Di Cato, L; Puxeddu, A, 1998)
"Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) of the 2,6-disubstituted naphthylalkanone class."2.41[Properties and features of nabumetone]. ( Davies, NM; McLachlan, AJ, 2000)
" The excellent tolerability of nabumetone and its 24-hour half-life, which provides the advantages of a once-daily dosage regimen, make it uniquely suitable for long term anti-inflammatory therapy in arthritis."2.41[Rationale for using nabumetone and clinical experience]. ( Roth, SH, 2000)
"Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) used to treat rheumatic and inflammatory conditions."1.29Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases. ( Buckley, MM; Friedel, HA; Langtry, HD, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's6 (54.55)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lennerz, JK1
Lauwers, GY1
Friedel, HA1
Langtry, HD1
Buckley, MM1
Giordano, N1
Senesi, M1
Battisti, E1
Gonnelli, S1
Franci, B1
Campagna, MS1
Mattii, G1
Palumbo, F1
Gennari, C1
Coaccioli, S1
Allegra, A1
Di Cato, L1
Puxeddu, A1
Davies, NM1
McLachlan, AJ1
Roth, SH1
Bianchi Porro, G1
Petrillo, M1
Ardizzone, S1
Caruso, I1
Montone, F1
Stroehmann, I2
Giersch, KH1
Zeidler, H1
Münzel, P2
Lemmel, EE1
Lemmel, EM1

Reviews

3 reviews available for nabumetone and Rheumatism

ArticleYear
[Properties and features of nabumetone].
    Drugs, 2000, Volume: 59 Spec No 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Humans; Nabumetone; Rheumatic Diseases

2000
[Rationale for using nabumetone and clinical experience].
    Drugs, 2000, Volume: 59 Spec No 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Humans; Nabumetone; Rheumatic Diseases

2000
Gastroscopic evaluation of the effects of nabumetone on the gastrointestinal mucosa of rheumatic patients.
    European journal of rheumatology and inflammation, 1991, Volume: 11, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Controlled Clinical Trials as Topic; Digestive S

1991

Trials

3 trials available for nabumetone and Rheumatism

ArticleYear
Clinical efficacy and tolerance of nabumetone in articular and non-articular rheumatic disorders: personal experience during 12 weeks of treatment.
    Panminerva medica, 1998, Volume: 40, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Female; Huma

1998
Efficacy and safety of nabumetone in patients with rheumatic diseases. Results of an outpatient study involving 8,865 patients.
    Drugs, 1990, Volume: 40 Suppl 5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Dose

1990
Efficacy and safety of nabumetone in 4,541 elderly patients from a drug monitoring study.
    Drugs, 1990, Volume: 40 Suppl 5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Evaluation; Female; Humans; Male; Nab

1990

Other Studies

5 other studies available for nabumetone and Rheumatism

ArticleYear
Amelanotic adenoma.
    International journal of surgical pathology, 2013, Volume: 21, Issue:5

    Topics: Adenoma; Butanones; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Female; Humans; Ibuprofen; Intes

2013
Nabumetone. A reappraisal of its pharmacology and therapeutic use in rheumatic diseases.
    Drugs, 1993, Volume: 45, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Gastric Mucosa; Hemodynamics; Humans; N

1993
Tolerability of nabumetone: a pilot in vitro study showing absence of injury to articular cartilage.
    International journal of tissue reactions, 1996, Volume: 18, Issue:4-6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cartilage, Articular; Case-Control Studie

1996
[Arthaxan--perspectives and alternatives in rheumatic therapy!].
    Der Internist, 1989, Volume: 30, Issue:4 Suppl [A

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Humans; Nabumetone; Rheumatic Diseases

1989
[Treatment of rheumatic diseases with nabumetone. Results of a study using the drug in 18,046 patients].
    Fortschritte der Medizin, 1988, Apr-20, Volume: 106, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu

1988