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nabumetone and Pain

nabumetone has been researched along with Pain in 9 studies

Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Diclofenac suppository, a non-steroidal anti-inflammatory drug (NSAID), is used widely in rheumatoid arthritis (RA) patients with severe arthritic pain."9.17A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis. ( Arimori, K; Chosa, E; Fujita, K; Kawai, K; Nishio, T; Ogata, K; Setoguchi, N; Takamura, N; Tokunaga, J; Yamamoto, R, 2013)
"In this double blind, randomized, parallel group study, 298 patients with rheumatoid arthritis received nabumetone (2000 mg/day) or naproxen (1000 mg/day) for 3 months."9.07Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients. ( Clarke, A; Cree, F; Emery, P; Kill, D; Poland, M; Redhead, R; Williams, P, 1992)
"Diclofenac suppository, a non-steroidal anti-inflammatory drug (NSAID), is used widely in rheumatoid arthritis (RA) patients with severe arthritic pain."5.17A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis. ( Arimori, K; Chosa, E; Fujita, K; Kawai, K; Nishio, T; Ogata, K; Setoguchi, N; Takamura, N; Tokunaga, J; Yamamoto, R, 2013)
"This study found no significant differences in pain relief or tolerability between treatment with SAMe or nabumetone over 8 weeks in Korean patients with knee OA."5.14Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients. ( Cha, HS; Kim, J; Koh, EM; Lee, CK; Lee, EY; Lee, KH; Lee, YJ; Ryu, H; Song, YW; Yoo, B, 2009)
"In this double blind, randomized, parallel group study, 298 patients with rheumatoid arthritis received nabumetone (2000 mg/day) or naproxen (1000 mg/day) for 3 months."5.07Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients. ( Clarke, A; Cree, F; Emery, P; Kill, D; Poland, M; Redhead, R; Williams, P, 1992)
"Nabumetone, 500 mg two nocte, was compared with naproxen, 250 mg two nocte and one mane, in the management of 24 patients with rheumatoid arthritis attending an outpatients clinic."5.05Nabumetone, a new non-steroidal anti-inflammatory drug: a comparison with naproxen. ( Burry, HC; Mowles, E; Richards, AM; Treadwell, BL; Tweed, JM, 1983)
"Forty-two patients with ankylosing spondylitis were entered into a double-blind study to compare treatment with indomethacin and a new non-steroidal anti-inflammatory drug, nabumetone."2.67A comparative study of nabumetone and indomethacin in ankylosing spondylitis. ( Palferman, TG; Webley, M, 1991)
"Nabumetone is an appropriate choice of nonsteroidal anti-inflammatory drug for the treatment of sports injury."2.66Nabumetone in the treatment of skin and soft tissue injury. ( Jenner, PN, 1987)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's4 (44.44)18.2507
2000's2 (22.22)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ike, RW1
Bole, GG1
Kim, J1
Lee, EY1
Koh, EM1
Cha, HS1
Yoo, B1
Lee, CK1
Lee, YJ1
Ryu, H1
Lee, KH1
Song, YW1
Setoguchi, N1
Takamura, N1
Fujita, K1
Ogata, K1
Tokunaga, J1
Nishio, T1
Chosa, E1
Arimori, K1
Kawai, K1
Yamamoto, R1
Richards, AM1
Burry, HC1
Treadwell, BL1
Tweed, JM1
Mowles, E1
Palferman, TG1
Webley, M1
Irani, M1
Emery, P1
Clarke, A1
Williams, P1
Kill, D1
Cree, F1
Redhead, R1
Poland, M1
Visentini, R1
Gottardo, R1
Zampa, A1
Sorbilli, G1
Vaiani, G1
Jenner, PN1

Reviews

1 review available for nabumetone and Pain

ArticleYear
Efficacy and improved safety--a new anti-arthritic agent.
    European journal of rheumatology and inflammation, 1991, Volume: 11, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Controlled C

1991

Trials

6 trials available for nabumetone and Pain

ArticleYear
Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients.
    Clinical therapeutics, 2009, Volume: 31, Issue:12

    Topics: Aged; Analgesics; Anti-Inflammatory Agents; Asian People; Butanones; Double-Blind Method; Female; Hu

2009
A diclofenac suppository-nabumetone combination therapy for arthritic pain relief and a monitoring method for the diclofenac binding capacity of HSA site II in rheumatoid arthritis.
    Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:2

    Topics: Aged; Arthritis, Rheumatoid; Binding Sites; Butanones; Cyclooxygenase Inhibitors; Diclofenac; Drug M

2013
Nabumetone, a new non-steroidal anti-inflammatory drug: a comparison with naproxen.
    The New Zealand medical journal, 1983, Dec-14, Volume: 96, Issue:745

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic; Double-Blind M

1983
A comparative study of nabumetone and indomethacin in ankylosing spondylitis.
    European journal of rheumatology and inflammation, 1991, Volume: 11, Issue:2

    Topics: Adult; Aged; Butanones; Double-Blind Method; Female; Humans; Indomethacin; Male; Middle Aged; Nabume

1991
Nabumetone compared with naproxen in the treatment of rheumatoid arthritis: a multicenter, double blind, randomized, parallel group trial in hospital outpatients.
    The Journal of rheumatology. Supplement, 1992, Volume: 36

    Topics: Adult; Ambulatory Care; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; D

1992
Nabumetone in the treatment of skin and soft tissue injury.
    The American journal of medicine, 1987, Oct-30, Volume: 83, Issue:4B

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butano

1987

Other Studies

2 other studies available for nabumetone and Pain

ArticleYear
Pseudoseptic arthritis due to acute lipoarthrosis in a systemic lupus erythematosus patient with osteonecrosis.
    Arthritis and rheumatism, 2009, Aug-15, Volume: 61, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Butanones; Diagnosis, Differen

2009
[A preliminary study on the tolerability and efficacy of nabumetone in the treatment of acute or chronic and very painful rheumatic diseases].
    La Clinica terapeutica, 1990, Jul-31, Volume: 134, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Drug Tolerance; Female; Humans; Joint Dis

1990