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nabumetone and Kidney Diseases

nabumetone has been researched along with Kidney Diseases in 3 studies

Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Nabumetone is a new, nonacidic, nonsteroidal antiinflammatory drug."2.38An overview of the clinical pharmacokinetics of nabumetone. ( Hyneck, ML, 1992)
" Pharmacokinetic assessment was made on the presence of the major and active metabolite found in the plasma, 6-methoxy-2-naphthylacetic acid, BRL 10720."1.27Nabumetone pharmacokinetics in patients with varying degrees of renal impairment. ( Boelaert, JR; Cooper, DL; Daneels, RF; Jonnaert, HA; Schurgers, ML; Thawley, AR; Undre, NA, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hyneck, ML1
Aronoff, GR1
Boelaert, JR1
Jonnaert, HA1
Daneels, RF1
Schurgers, ML1
Thawley, AR1
Undre, NA1
Cooper, DL1

Reviews

2 reviews available for nabumetone and Kidney Diseases

ArticleYear
An overview of the clinical pharmacokinetics of nabumetone.
    The Journal of rheumatology. Supplement, 1992, Volume: 36

    Topics: Adult; Aged; Aging; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Eating; Humans; Ki

1992
Therapeutic implications associated with renal studies of nabumetone.
    The Journal of rheumatology. Supplement, 1992, Volume: 36

    Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Clinical Trials as Topic; Double-Blind Me

1992

Other Studies

1 other study available for nabumetone and Kidney Diseases

ArticleYear
Nabumetone pharmacokinetics in patients with varying degrees of renal impairment.
    The American journal of medicine, 1987, Oct-30, Volume: 83, Issue:4B

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Female; Humans; Kidney Diseases; Ma

1987