Page last updated: 2024-10-31

nabumetone and Hemorrhage, Peptic Ulcer

nabumetone has been researched along with Hemorrhage, Peptic Ulcer in 3 studies

Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

Research Excerpts

ExcerptRelevanceReference
"The results suggest that nabumetone was similar in efficacy by most criteria to diclofenac SR and piroxicam in relieving the symptoms of osteoarthritis; however, nabumetone's GI safety profile was generally superior to that of both comparator NSAIDs."9.09Safety and efficacy of nabumetone in osteoarthritis: emphasis on gastrointestinal safety. ( Palmer, RH; Scott, DL, 2000)
"The results suggest that nabumetone was similar in efficacy by most criteria to diclofenac SR and piroxicam in relieving the symptoms of osteoarthritis; however, nabumetone's GI safety profile was generally superior to that of both comparator NSAIDs."5.09Safety and efficacy of nabumetone in osteoarthritis: emphasis on gastrointestinal safety. ( Palmer, RH; Scott, DL, 2000)
"To evaluate the efficacy and gastrointestinal safety of nabumetone and diclofenac in the treatment of elderly patients with osteoarthritis, participating in a 3-month efficacy trial."5.09Treatment of elderly patients with nabumetone or diclofenac: gastrointestinal safety profile. ( DeLapp, R; Kaine, J; Morgan , GJ; Palmer, R, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scott, DL1
Palmer, RH1
Sung, JJ1
Morgan , GJ1
Kaine, J1
DeLapp, R1
Palmer, R1

Reviews

1 review available for nabumetone and Hemorrhage, Peptic Ulcer

ArticleYear
Management of nonsteroidal anti-inflammatory drug-related peptic ulcer bleeding.
    The American journal of medicine, 2001, Jan-08, Volume: 110, Issue:1A

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Butanone

2001

Trials

2 trials available for nabumetone and Hemorrhage, Peptic Ulcer

ArticleYear
Safety and efficacy of nabumetone in osteoarthritis: emphasis on gastrointestinal safety.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Digestive System; Double-Blind Meth

2000
Treatment of elderly patients with nabumetone or diclofenac: gastrointestinal safety profile.
    Journal of clinical gastroenterology, 2001, Volume: 32, Issue:4

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Butanones; D

2001