nabumetone has been researched along with Gastric Ulcer in 8 studies
Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Celecoxib and indometacin both decreased the epithelial proliferative response and delayed healing of cryoprobe-induced gastric ulcers." | 3.71 | Effects of NSAIDs on cryoprobe-induced gastric ulcer healing in rats. ( Bjarnason, I; Caldwell, C; Palmer, RH; Sigthorsson, G; Tibble, J, 2001) |
| " When the possibility of poor compliance and the potential adverse effects of misoprostol are considered, rebamipide appears to be a clinically effective and safe alternative." | 2.79 | Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity. ( Cho, CS; Kang, YM; Kim, JH; Kim, SK; Lee, DH; Lee, SK; Lee, ST; Lee, YC; Park, SH; Park, W; Park, YW; Rew, JS; Yoo, WH, 2014) |
| "Nabumetone is a compound of novel structure which displays acute anti-inflammatory activity in the carrageenan-induced oedema model in rats and the ultraviolet-induced erythema model in guinea-pigs." | 1.26 | Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent. ( Boyle, EA; Freeman, PC; Mangan, FR; Thomson, MJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, JH | 1 |
| Park, SH | 1 |
| Cho, CS | 1 |
| Lee, ST | 1 |
| Yoo, WH | 1 |
| Kim, SK | 1 |
| Kang, YM | 1 |
| Rew, JS | 1 |
| Park, YW | 1 |
| Lee, SK | 1 |
| Lee, YC | 1 |
| Park, W | 1 |
| Lee, DH | 1 |
| Yıldırım, E | 1 |
| Sağıroğlu, O | 1 |
| Kılıç, FS | 1 |
| Erol, K | 1 |
| Boyle, EA | 1 |
| Freeman, PC | 1 |
| Mangan, FR | 1 |
| Thomson, MJ | 1 |
| Cardin, S | 1 |
| Soll, AH | 1 |
| Taché, Y | 1 |
| Lems, WF | 1 |
| van Berge Henegouwen, GP | 1 |
| Bijlsma, JW | 1 |
| Cantu, TG | 1 |
| Lipani, JA | 1 |
| van Rijthoven, AW | 1 |
| Tibble, J | 1 |
| Sigthorsson, G | 1 |
| Caldwell, C | 1 |
| Palmer, RH | 1 |
| Bjarnason, I | 1 |
1 review available for nabumetone and Gastric Ulcer
| Article | Year |
|---|---|
['Stomach-friendly' NSAIDs: careful optimism?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Butanones; Gastritis; Humans; Ibuprofen; Misopro | 1995 |
1 trial available for nabumetone and Gastric Ulcer
| Article | Year |
|---|---|
Preventive efficacy and safety of rebamipide in nonsteroidal anti-inflammatory drug-induced mucosal toxicity.
Topics: Adult; Aged; Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Butanon | 2014 |
6 other studies available for nabumetone and Gastric Ulcer
| Article | Year |
|---|---|
Effects of nabumetone and dipyrone on experimentally induced gastric ulcers in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Cyclooxygenase 1; Cyclooxygenase 2; Cyc | 2013 |
Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Butanones; F | 1982 |
Different effects of indomethacin and nabumetone on prostaglandin-mediated gastric responses to central vagal activation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Gastric Juice; Indomethacin; Male; Nabu | 1995 |
Gastrointestinal ulceration with NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Duodenal Ulcer; Humans; Nabumetone; Stomach Ulce | 1995 |
[Stomach-friendly NSAIDs: careful optimism?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Humans; Nabumetone; Stomach Ulcer | 1995 |
Effects of NSAIDs on cryoprobe-induced gastric ulcer healing in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cell Division; Cyclooxygenas | 2001 |