nabumetone has been researched along with Gastric Diseases in 4 studies
Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nabumetone is a nonsteroidal anti-inflammatory prodrug, which exerts its pharmacological effects via the metabolite 6-methoxy-2-naphthylacetic acid (6-MNA)." | 6.42 | Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis. ( Ekbom, A; Hedner, T; Samulesson, O; Ung, KA; Wadenvik, H; Währborg, P, 2004) |
| " In an ongoing study of patients with osteo- or rheumatoid arthritis, currently in its fourth year, nabumetone has been shown to be relatively gastric sparing when compared with naproxen." | 5.06 | New understandings of NSAID gastropathy. ( Roth, SH, 1989) |
| "Nabumetone is a nonsteroidal anti-inflammatory prodrug, which exerts its pharmacological effects via the metabolite 6-methoxy-2-naphthylacetic acid (6-MNA)." | 2.42 | Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis. ( Ekbom, A; Hedner, T; Samulesson, O; Ung, KA; Wadenvik, H; Währborg, P, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, W | 1 |
| Wang, YM | 1 |
| Li, SL | 1 |
| Yan, M | 1 |
| Li, D | 1 |
| Chen, BY | 1 |
| Cheng, NN | 1 |
| Hedner, T | 1 |
| Samulesson, O | 1 |
| Währborg, P | 1 |
| Wadenvik, H | 1 |
| Ung, KA | 1 |
| Ekbom, A | 1 |
| Houben, JJ | 1 |
| Liem, B | 1 |
| Roth, SH | 1 |
1 review available for nabumetone and Gastric Diseases
| Article | Year |
|---|---|
Nabumetone: therapeutic use and safety profile in the management of osteoarthritis and rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bu | 2004 |
1 trial available for nabumetone and Gastric Diseases
| Article | Year |
|---|---|
New understandings of NSAID gastropathy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Butanones; Clinical Trials as Topic | 1989 |
2 other studies available for nabumetone and Gastric Diseases
| Article | Year |
|---|---|
Risk factors of adverse drug reaction from non-steroidal anti-inflammatory drugs in Shanghai patients with arthropathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheu | 2004 |
[Effectiveness, safety, and costs of measures for prevention of gastropathy due to the use of nonsteroidal antiinflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Clinical Trials as Topic; Confounding | 1999 |