nabumetone has been researched along with Cirrhosis, Liver in 2 studies
Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the patients with liver insufficiency the mean values of Cmax and AUC0-24 h for 6-methoxy-2-naphthylacetic acid were 26." | 1.27 | Liver insufficiency as a factor modifying the pharmacokinetic characteristic of the preparation nabumetone. ( Bacracheva, N; Dierdorf, D; Gruev, I; Kostova, N; Maleev, A; Vlahov, V, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Terziivanov, D | 1 |
| Maleev, A | 2 |
| Vlahov, V | 2 |
| Gruev, I | 1 |
| Dierdorf, D | 1 |
| Kostova, N | 1 |
| Bacracheva, N | 1 |
2 other studies available for nabumetone and Cirrhosis, Liver
| Article | Year |
|---|---|
Nabumetone (BRL 14777) presystemic elimination and disposition in patients with liver impairments.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Female; gamma-Glutamyltransferase; Humans; Kinet | 1987 |
Liver insufficiency as a factor modifying the pharmacokinetic characteristic of the preparation nabumetone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Female; Humans; Kinetics; Liver Cirrhosis; | 1986 |