nabumetone has been researched along with Body Weight in 3 studies
Nabumetone: A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS.
nabumetone : A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 6-month, double-blind, controlled, randomized, parallel study was performed to compare the efficacy and tolerance of nabumetone (1000 mg at bedtime) with naproxen (250 mg twice daily) in the treatment of osteoarthritis." | 9.06 | A 6-month, double-blind study comparing nabumetone to naproxen in the treatment of osteoarthritis. ( Goodman, LA; Pisko, EJ; Rice, D; Strader, K; White, R, 1987) |
| "A 6-month, double-blind, controlled, randomized, parallel study was performed to compare the efficacy and tolerance of nabumetone (1000 mg at bedtime) with naproxen (250 mg twice daily) in the treatment of osteoarthritis." | 5.06 | A 6-month, double-blind study comparing nabumetone to naproxen in the treatment of osteoarthritis. ( Goodman, LA; Pisko, EJ; Rice, D; Strader, K; White, R, 1987) |
| "Repeat oral dosing of nabumetone for 1 month maintains anti-inflammatory efficacy in a carrageenan model of paw oedema yet does not cause gastrointestinal damage." | 3.68 | Anti-inflammatory efficacy and gastrointestinal irritancy: comparative 1 month repeat oral dose studies in the rat with nabumetone, ibuprofen and diclofenac. ( Blower, PR; Gentry, C; Melarange, R; O'Connell, C, 1991) |
| "Nabumetone proved to be an effective anti-inflammatory agent that was devoid of gastrointestinal irritancy." | 1.29 | Nabumetone, an effective anti-inflammatory agent, lacks gastrointestinal irritancy in the rat when dosed orally for one month: comparison with tiaprofenic acid and etodolac. ( Blower, PR; Gentry, C; Melarange, R; Spangler, R; Toseland, CD, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Melarange, R | 2 |
| Gentry, C | 2 |
| Blower, PR | 2 |
| Toseland, CD | 1 |
| Spangler, R | 1 |
| O'Connell, C | 1 |
| Pisko, EJ | 1 |
| Strader, K | 1 |
| Rice, D | 1 |
| White, R | 1 |
| Goodman, LA | 1 |
1 trial available for nabumetone and Body Weight
| Article | Year |
|---|---|
A 6-month, double-blind study comparing nabumetone to naproxen in the treatment of osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Butanones; Clinic | 1987 |
2 other studies available for nabumetone and Body Weight
| Article | Year |
|---|---|
Nabumetone, an effective anti-inflammatory agent, lacks gastrointestinal irritancy in the rat when dosed orally for one month: comparison with tiaprofenic acid and etodolac.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Butanones; Carr | 1994 |
Anti-inflammatory efficacy and gastrointestinal irritancy: comparative 1 month repeat oral dose studies in the rat with nabumetone, ibuprofen and diclofenac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Butanones; Carrageenan; Diclofenac; E | 1991 |