nabilone and Testicular-Neoplasms

nabilone has been researched along with Testicular-Neoplasms* in 2 studies

Trials

1 trial(s) available for nabilone and Testicular-Neoplasms

ArticleYear
Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy.
    Klinische Wochenschrift, 1986, Apr-15, Volume: 64, Issue:8

    Twenty nonseminomatous testicular cancer patients not pretreated with emetogenic chemotherapy were included in a crossover study of antiemetic therapy. Patients were randomly assigned to receive either nabilone (2 X 2 mg/day) or alizapride (3 X 150 mg/day) prior to beginning low-dose cisplatin chemotherapy. Patients on nabilone had significantly fewer episodes of emesis than those on alizapride (medians, 1.1 vs 2.9; p less than 0.01). Nabilone was superior to alizapride in giving complete relief from nausea (medians, 65% vs 30%; p less than 0.01), and was more effective in shortening the duration of nausea (medians, 1.3 h vs 5.1 h; p less than 0.01); however, it caused more adverse effects. It is concluded that nabilone has greater antiemetic activity than alizapride in young patients receiving low-dose cisplatin chemotherapy. Nabilone dosage should be reduced to decrease the incidence and degree of adverse reactions while leaving the definite antiemetic activity unchanged.

    Topics: Administration, Oral; Adult; Antiemetics; Cisplatin; Dose-Response Relationship, Drug; Dronabinol; Humans; Male; Middle Aged; Pyrrolidines; Testicular Neoplasms; Vomiting

1986

Other Studies

1 other study(ies) available for nabilone and Testicular-Neoplasms

ArticleYear
Cannabinoids and hCG levels in patients with testicular cancer.
    Lancet (London, England), 1983, Nov-12, Volume: 2, Issue:8359

    Topics: Antiemetics; Chorionic Gonadotropin; Dronabinol; Humans; Male; Testicular Neoplasms

1983