n-nonyl-1-deoxynojirimycin has been researched along with Inflammation* in 1 studies
1 other study(ies) available for n-nonyl-1-deoxynojirimycin and Inflammation
| Article | Year |
|---|---|
Exploring the effect of chirality on the therapeutic potential of N-alkyl-deoxyiminosugars: anti-inflammatory response to Pseudomonas aeruginosa infections for application in CF lung disease.
In the frame of a research program aimed to explore the relationship between chirality of iminosugars and their therapeutic potential, herein we report the synthesis of N-akyl l-deoxyiminosugars and the evaluation of the anti-inflammatory properties of selected candidates for the treatment of Pseudomonas aeruginosa infections in Cystic Fibrosis (CF) lung disease. Target glycomimetics were prepared by the shortest and most convenient approach reported to date, relying on the use of the well-known PS-TPP/I Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; beta-Glucosidase; Bronchi; Cystic Fibrosis; Dose-Response Relationship, Drug; Humans; Imino Sugars; Inflammation; Inhibitory Concentration 50; Mice; Neutrophils; Pseudomonas aeruginosa; Pseudomonas Infections; Stereoisomerism | 2019 |