n-nitrosomorpholine has been researched along with Precancerous Conditions in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (40.32) | 18.7374 |
| 1990's | 27 (43.55) | 18.2507 |
| 2000's | 8 (12.90) | 29.6817 |
| 2010's | 2 (3.23) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahr, HJ; Bannasch, P; Ellinger-Ziegelbauer, H; Glückmann, M; Gundert-Remy, U; Hellmann, J; Ittrich, C; Kiss, E; Kopp-Schneider, A; Kramer, PJ; Krause, E; Kröger, M; Oberemm, A; Richter-Reichhelm, HB; Scholz, G; Seemann, K; Weimer, M | 1 |
| Aleem, E; Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D | 1 |
| Birth, M; Calvisi, DF; Cigliano, A; Dombrowski, F; Heidecke, CD; Peters, M; Rausch, J; Ribback, S; Sailer, V | 1 |
| de Gunst, MC; Dewanji, A; Luebeck, EG | 1 |
| Dombrowski, F; Evert, M; Jost, CM; Manekeller, S | 1 |
| Guenthner, TM; Krischan, R; Kuhlmann, WD; Kunz, W; Oesch, F | 1 |
| Bannasch, P; Hacker, HJ; Kunz, HW; Moore, MA | 1 |
| Ohde, G; Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I | 1 |
| Buchmann, A; Kunz, W; Schwarz, M; Wiesbeck, G | 1 |
| Bannasch, P; Hacker, HJ; Mayer, D; Moore, MA | 1 |
| Bannasch, P; Hacker, HJ; Klimek, F; Mayer, D | 1 |
| Roome, N; Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I | 1 |
| Bannasch, P; Klimek, F; Mayer, D | 2 |
| de Gerlache, J; Fort, L; Lans, M; Roberfroid, M; Taper, HS | 1 |
| Bannasch, P; Hacker, HJ; Moore, MA | 1 |
| Bannasch, P; Benner, U; Hacker, HJ; Klimek, F; Mayer, D; Moore, M; Zerban, H | 1 |
| Bannasch, P; Mayer, D; Moore, MA | 1 |
| Bannach, P; Enzmann, H; Kopp-Schneider, A; Löser, E; Zerban, H | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H | 2 |
| Bannasch, P; Kopp-Schneider, A; Radig, S; Zerban, H | 1 |
| Bannasch, P; Weber, E | 3 |
| Ruan, YB; Wu, ZB | 1 |
| Bannasch, P; Klimek, F | 3 |
| Futakuchi, M; Hasegawa, R; Hirose, M; Ito, N; Lijinsky, W; Shirai, T | 1 |
| Bannasch, P; Klimek, F; Mayer, D; Rempel, A | 1 |
| Baba, M; Iishi, H; Tatsuta, M; Yamamoto, R | 1 |
| de Gunst, MC; Luebeck, EG | 1 |
| Bannasch, P; Klimek, F; Kopp-Schneider, A; Ströbel, P; Zerban, H | 1 |
| Eigenbrodt, E; Klingelhöffer, A; Oesch, F; Schäfer, A; Steinberg, P; Weisse, G; Wüst, G | 1 |
| Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D | 1 |
| Grasl-Kraupp, B; Hufnagl, K; Löw-Baselli, A; Parzefall, W; Schulte-Hermann, R | 1 |
| Bukowska, K; Grasl-Kraupp, B; Huber, WW; Käfer, M; Löw-Baselli, A; Schulte-Hermann, R | 1 |
| Fukushima, S; Iwai, S; Morimura, K; Nomura, T; Takayama, R; Wanibuchi, H; Wei, M; Yamamoto, S | 1 |
| Geisler, I; Kopp-Schneider, A | 1 |
| Baba, M; Iishi, H; Tatsuta, M | 1 |
| Bannasch, P; Pekel, E; Schiebel, K; Stumpf, H; Zerban, H | 1 |
| Enzmann, H; Kaliner, G; Löser, E; Watta-Gebert, B | 1 |
| Bursch, W; Gerbracht, U; Kraus, P; Putz, B; Reinacher, M; Schulte-Hermann, R; Timmermann-Trosiener, I | 1 |
| Luebeck, EG; Moolgavkar, SH | 2 |
| Bock, KW; Dirheimer, G; Keith, G; Münzel, PA; Pfohl-Leszkowicz, A; Röhrdanz, E | 1 |
| de Gunst, M; Luebeck, EG; Moolgavkar, SH; Port, RE; Schwarz, M | 1 |
| Barthel, G; Bursch, W; Schulte-Hermann, R; Timmermann-Trosiener, I | 1 |
| Bannasch, P; Dettler, T; Enzmann, H; Ohlhauser, D; Stumpf, H | 1 |
| Bock, KW; Fischer, G; Kobusch, AB | 1 |
| Baba, M; Iishi, H; Tatsuta, M; Wada, A; Yamamoto, R | 1 |
| Bock, KW; Fischer, G; Ulrich, D | 1 |
| de Gerlache, J; Lans, M; Préat, V; Roberfroid, M; Taper, H | 1 |
| Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I | 1 |
| Bannasch, P; Hacker, HJ; Ito, N; Katayama, H; Masui, T; Tsuda, H | 1 |
| Bannasch, P; Enzmann, H | 2 |
| Boix, J; Callaghan, R; Gil, R; Llombart-Bosch, A; Pellin, A | 1 |
| Bannasch, P; Moore, MA; Weber, E | 1 |
| Bannasch, P; Ehemann, V; Hacker, HJ; Mayer, D | 1 |
| Bannasch, P; Edler, L; Enzmann, H | 1 |
3 review(s) available for n-nitrosomorpholine and Precancerous Conditions
| Article | Year |
|---|---|
Cytochemical and biochemical microanalysis of carcinogenesis.
Topics: Animals; Histocytochemistry; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Microscopy, Electron; Neoplasms; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats | 1981 |
Hexokinase expression in liver preneoplasia and neoplasia.
Topics: Animals; Carcinogens; Carcinoma; Glucokinase; Hexokinase; Isoenzymes; Kinetics; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats | 1997 |
The role of somatic mutations and cell replication kinetics in quantitative cancer risk assessment.
Topics: Adenosine Triphosphatases; Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Cell Division; Liver; Liver Neoplasms; Mutation; Nitrosamines; Precancerous Conditions; Rats; Risk Factors | 1991 |
59 other study(ies) available for n-nitrosomorpholine and Precancerous Conditions
| Article | Year |
|---|---|
Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters.
Topics: Animals; Biomarkers, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Proteomics; Rats; Rats, Wistar; Toxicogenetics | 2009 |
Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glycogen; Insulin Receptor Substrate Proteins; Male; MAP Kinase Kinase 1; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, Insulin; Up-Regulation | 2011 |
Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis.
Topics: Animals; Cell Proliferation; Fatty Acids; Female; Humans; Lipogenesis; Liver; Liver Neoplasms, Experimental; Male; MAP Kinase Signaling System; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew; TOR Serine-Threonine Kinases | 2013 |
Exploring heterogeneity in tumour data using Markov chain Monte Carlo.
Topics: Animals; Bayes Theorem; Liver Neoplasms; Markov Chains; Models, Biological; Monte Carlo Method; Nitrosamines; Poisson Distribution; Precancerous Conditions; Rats; Stochastic Processes | 2003 |
Cocarcinogenic effects of islet hormones and N-nitrosomorpholine in hepatocarcinogenesis after intrahepatic transplantation of pancreatic islets in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Carcinogens; Cocarcinogenesis; Diabetes Mellitus, Experimental; Islets of Langerhans Transplantation; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew | 2005 |
Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis.
Topics: Adenosine Triphosphatases; Animals; Epoxide Hydrolases; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Microsomes, Liver; Nitrosamines; Precancerous Conditions; Rabbits; Rats | 1981 |
Enhancement of NNM-induced carcinogenesis in the rat liver by phenobarbital: a combined morphological and enzyme histochemical approach.
Topics: Acyltransferases; Animals; Carcinogens; Cell Transformation, Neoplastic; Drug Synergism; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Transglutaminases | 1983 |
Effect of tumor promoters on proliferation of putative preneoplastic cells in rat liver.
Topics: Animals; Carcinogens; Cell Division; Cyproterone; Cyproterone Acetate; Eating; Female; Hexachlorocyclohexane; Liver; Liver Neoplasms; Male; Mitotic Index; Nitrosamines; Precancerous Conditions; Progesterone; Rats; Rats, Inbred Strains | 1982 |
Effect of ethanol on early stages in nitrosamine carcinogenesis in rat liver.
Topics: Adenosine Triphosphatases; Alcoholism; Animals; Carcinogens; Diethylnitrosamine; Female; Humans; Liver Neoplasms; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1983 |
Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver.
Topics: Animals; Carcinogens; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glyceraldehyde-3-Phosphate Dehydrogenases; Histocytochemistry; Liver; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1982 |
Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Carcinogens; Cell Transformation, Neoplastic; Glucosephosphate Dehydrogenase; Glycogen Storage Disease; Humans; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1984 |
Immunocytochemical demonstration of a phenobarbital-inducible cytochrome P450 in putative preneoplastic foci of rat liver.
Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Histocytochemistry; Liver; Liver Neoplasms; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains | 1984 |
Biochemical microanalysis of glycogen content and glucose-6-phosphate dehydrogenase activity in focal lesions of the rat liver induced by N-nitrosomorpholine.
Topics: Animals; Carcinogens; Glucosephosphate Dehydrogenase; Glycogen; Liver; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1984 |
Morphological alterations and DNase deficiency in phenobarbital promotion of N-nitrosomorpholine initiated rat hepatocarcinogenesis.
Topics: Animals; Carcinogens; Deoxyribonucleases; Drug Synergism; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains | 1983 |
Phenotypic instability in focal and nodular lesions induced in a short term system in the rat liver.
Topics: Animals; Carcinogens; Enzymes; Glycogen; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1983 |
The dose dependence and sequential appearance of putative preneoplastic populations induced in the rat liver by stop experiments with N-nitrosomorpholine.
Topics: Animals; Carcinogens; Cell Nucleus; Cytoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Glycogen; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1982 |
Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis.
Topics: Animals; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley | 1995 |
Inhibition by somatostatin of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
Topics: Animals; Body Weight; Carcinogens; gamma-Glutamyltransferase; Gastrins; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Organ Size; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Somatostatin | 1993 |
Cell proliferation and cell death (apoptosis) in hepatic preneoplasia and neoplasia are closely related to phenotypic cellular diversity and instability.
Topics: Animals; Apoptosis; Cell Division; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thymidine | 1994 |
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine.
Topics: Administration, Oral; Animals; Carcinogens; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiments by oral exposure to N-nitrosomorpholine.
Topics: Administration, Oral; Animals; Carcinogens; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholine.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
[Study on the relationship between most cells and tumor growth speed during hepatocarcinogenesis in the rats].
Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Mast Cells; Nitrosamines; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Silver Staining | 1993 |
Isoenzyme shift from glucokinase to hexokinase is not an early but a late event in hepatocarcinogenesis.
Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Glucokinase; Hexokinase; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat.
Topics: Animals; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Nitroso Compounds; Precancerous Conditions; Rats; Rats, Inbred F344 | 1996 |
Ha-ras mutations in N-nitrosomorpholine-induced lesions and inhibition of hepatocarcinogenesis by antisense sequences in rat liver.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Evaluation Studies as Topic; Genes, ras; Injections, Intraperitoneal; Liver Neoplasms; Male; Mutation; Nitrosamines; Oligonucleotides, Antisense; Point Mutation; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1997 |
A method for parametric estimation of the number and size distribution of cell clusters from observations in a section plane.
Topics: Algorithms; Animals; Biometry; Carcinogens; Cell Count; Cell Division; Cocarcinogenesis; Likelihood Functions; Liver; Liver Neoplasms, Experimental; Male; Models, Biological; Nitrosamines; Precancerous Conditions; Rats; Rats, Wistar; Stochastic Processes | 1998 |
Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells.
Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Enzyme Activation; Glucagon; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Substrate Specificity; Time Factors | 1998 |
Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine.
Topics: Animals; Carcinogens; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1998 |
Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats.
Topics: Animals; Carcinogens; Isoenzymes; Liver; Male; Nitrosamines; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Wistar | 1999 |
Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone.
Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Female; Glycogen; Immunohistochemistry; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Nitrosamines; Phosphoproteins; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1999 |
Initiated rat hepatocytes in primary culture: a novel tool to study alterations in growth control during the first stage of carcinogenesis.
Topics: Animals; Cell Division; Cells, Cultured; Cyproterone Acetate; DNA; Glutathione Transferase; Liver; Liver Neoplasms; Male; Nitrosamines; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Wistar; Transforming Growth Factor beta | 2000 |
Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Carcinogens; Cell Division; DNA; Eating; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Monoterpenes; Nitrosamines; Phenobarbital; Precancerous Conditions; Proteins; Rats; Rats, Wistar; Terpenes | 2000 |
Chemopreventive effects of S-methylcysteine on rat hepatocarcinogenesis induced by concurrent administration of sodium nitrite and morpholine.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Cysteine; Drug Interactions; Food Preservatives; Gastric Mucosa; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Morpholines; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Sodium Nitrite | 2000 |
A model for hepatocarcinogenesis with clonal expansion of three successive phenotypes of preneoplastic cells.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Likelihood Functions; Liver Neoplasms; Male; Models, Biological; Nitrosamines; Numerical Analysis, Computer-Assisted; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 2000 |
Transfer of bcl-xs plasmid is effective in preventing and inhibiting rat hepatocellular carcinoma induced by N-nitrosomorpholine.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Electroporation; Gene Expression; Genetic Therapy; Injections, Intralesional; Liposomes; Liver Neoplasms, Experimental; Male; Nitrosamines; Plasmids; Precancerous Conditions; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2001 |
Altered transferrin gene expression in preneoplastic and neoplastic liver lesions induced in rats with N-nitrosomorpholine.
Topics: Animals; Chemical and Drug Induced Liver Injury; DNA; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; In Situ Hybridization; Iron; Liver Diseases; Liver Glycogen; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Neoplasm; Transferrin | 1992 |
Foci of altered hepatocytes induced in embryonal turkey liver.
Topics: Animals; Glucosephosphate Dehydrogenase; Glycogen; Liver; Liver Neoplasms; Nitrosamines; Precancerous Conditions; Turkeys; Urethane | 1992 |
Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.
Topics: Animals; Body Weight; Carcinogens; Cell Survival; Clofibrate; Cyproterone; Cyproterone Acetate; Female; Glutathione Transferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Nafenopin; Nitrosamines; Organ Size; Phenobarbital; Phenotype; Precancerous Conditions; Propionates; Rats; Rats, Inbred Strains | 1990 |
Stochastic analysis of intermediate lesions in carcinogenesis experiments.
Topics: Adenosine Triphosphatases; Animals; Carcinogens; Cell Division; Female; Liver Neoplasms, Experimental; Models, Biological; Models, Statistical; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew; Stochastic Processes | 1991 |
Site-specific hypomethylation of c-myc protooncogene in liver nodules and inhibition of DNA methylation by N-nitrosomorpholine.
Topics: Animals; Deoxycytidine; DNA Modification Methylases; DNA, Bacterial; DNA, Neoplasm; Liver Neoplasms; Male; Methylation; Nitrosamines; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred Strains; RNA, Neoplasm | 1991 |
Inhibition by neostigmine of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
Topics: Animals; gamma-Glutamyltransferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Neostigmine; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Vagotomy | 1990 |
Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis experiments--I. Single agent regimen.
Topics: Adenosine Triphosphatases; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Liver Neoplasms, Experimental; Mathematics; Models, Biological; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew | 1990 |
DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion.
Topics: Animals; Body Weight; Carcinogens; Cell Division; DNA Replication; Female; Liver; Liver Neoplasms; Nitrosamines; Organ Size; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Inbred Strains; Thymidine | 1990 |
Biochemical microanalysis of pyruvate kinase activity in preneoplastic and neoplastic liver lesions induced in rats by N-nitrosomorpholine.
Topics: Animals; Carcinogens; Glycogen; Isoenzymes; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Inbred Strains | 1990 |
Dietary fructose enhances the development of atypical acinar cell nodules in the pancreas of rats pretreated with N-nitrosomorpholine.
Topics: Animals; Carcinogens; Carcinoma; Dietary Carbohydrates; Drug Synergism; Fructose; Male; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains | 1990 |
Tumor-promoting activity and cytotoxicity of 3,4,3',4'-tetrachlorobiphenyl on N-nitrosomorpholine-induced murine liver foci.
Topics: Adenoma, Bile Duct; Animals; Carcinogens; Enzyme Induction; Glucose-6-Phosphatase; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Nitrosamines; Polychlorinated Biphenyls; Precancerous Conditions | 1989 |
Role of glucose-6-phosphate dehydrogenase on enhanced proliferation of pre-neoplastic and neoplastic cells in rat liver induced by N-nitrosomorpholine.
Topics: Animals; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Biochemical microanalysis of alpha-glucosidase activity in preneoplastic and neoplastic hepatic lesions induced in rats by N-nitrosomorpholine.
Topics: alpha-Glucosidases; Animals; Histocytochemistry; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Effects of N-nitrosomorpholine and phenobarbital on UDP-glucuronyltransferase in putative preneoplastic foci of rat liver.
Topics: Adenosine Triphosphatases; Animals; Aryl Hydrocarbon Hydroxylases; gamma-Glutamyltransferase; Glucuronosyltransferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains | 1985 |
Influence of the nature and the dose of the initiator on the development of premalignant and malignant lesions in rat hepatocarcinogenesis.
Topics: Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors | 1986 |
Facilitated expression of adaptive responses to phenobarbital in putative pre-stages of liver cancer.
Topics: Adaptation, Physiological; Animals; Cytochrome P-450 Enzyme System; DNA; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines.
Topics: Animals; Carcinogens; Diethylnitrosamine; Glycolysis; Kidney; Kidney Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Morphometric study of alterations of extrafocal hepatocytes of rat liver treated with N-nitrosomorpholine.
Topics: Animals; Carcinogens; Cell Nucleus; Liver; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Morphometric and cytophotometric nuclear analysis of altered hepatocyte foci induced by N-nitrosomorpholine (NNM) and aflatoxin B1 (AFB1) in liver of Wistar rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1988 |
Enzyme histochemical and morphological phenotype of amphophilic foci and amphophilic/tigroid cell adenomas in rat liver after combined treatment with dehydroepiandrosterone and N-nitrosomorpholine.
Topics: Animals; Carcinogens; Dehydroepiandrosterone; Drug Interactions; Liver; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1988 |
Non-persisting early foci of altered hepatocytes induced in rats by N-nitrosomorpholine.
Topics: Animals; Glucosephosphate Dehydrogenase; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1988 |
Loss of adenylate cyclase activity in preneoplastic and neoplastic lesions induced in rat liver by N-nitrosomorpholine.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cholera Toxin; Colforsin; Glucagon; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms; Male; Microscopy, Electron; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains | 1986 |
Simple elementary method for the quantification of focal liver lesions induced by carcinogens.
Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Time Factors | 1987 |