n-nitrosomorpholine has been researched along with Hepatocellular Carcinoma in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 3 (14.29) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, X; Hou, J; Liu, SF; Song, L; Zhang, HL; Zhang, JG; Zheng, L | 1 |
| Baydar, T; Erkekoglu, P | 1 |
| Chen, H; Han, SJ; Jia, WD; Liu, WB; Ren, WH; Wang, W; Wang, YC; Xu, GL; Zhang, CH | 1 |
| Aleem, E; Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D | 1 |
| Hwang, TH; Jeong, JS; Kim, YH; Kim, YJ; Kwon, EY; Nam, KJ; Oh, JY; Park, BH | 1 |
| Choi, YC; Jeong, JS; Jung, KJ; Kim, IH; Kim, SS; Lee, SH; Park, WY | 1 |
| Aleem, E; Bannasch, P; Flohr, T; Mayer, D; Thielmann, HW | 1 |
| Cho, YM; Futakuchi, M; Imai, N; Ogawa, K; Shirai, T; Takeshita, F; Tamano, S; Yoshino, H | 1 |
| Chalupa, I; Kogan, G; Slamenova, D; Smigova, J; Sramkova, M | 1 |
| Llombart Bosch, A; Peydro Olaya, A | 1 |
| Kuhlmann, WD | 1 |
| Bannasch, P; Klimek, F | 1 |
| Futakuchi, M; Imai, T; Inada, K; Masui, T; Mizoguchi, Y; Nakanishi, H; Shirai, T; Tatematsu, M; Yada, H | 1 |
| Baba, M; Iishi, H; Tatsuta, M; Yamamoto, R | 1 |
| Bannasch, P; Mayer, D; Metzger, C | 1 |
| Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D | 1 |
| Futakuchi, M; Hirose, M; Kato, K; Ogawa, K; Ogiso, T; Sano, M; Shirai, T | 1 |
| Baba, M; Iishi, H; Tatsuta, M | 2 |
| Taper, HS | 1 |
| Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H | 1 |
21 other study(ies) available for n-nitrosomorpholine and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Establishment of rat liver cancer cell lines with different metastatic potential.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Diethylnitrosamine; Disease Models, Animal; Karyotyping; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Nitrosamines; Rats | 2020 |
Evaluation of the protective effect of ascorbic acid on nitrite- and nitrosamine-induced cytotoxicity and genotoxicity in human hepatoma line.
Topics: Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Survival; Comet Assay; Cytoprotection; Diethylnitrosamine; Dimethylnitrosamine; DNA Damage; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Liver Neoplasms; Mutagens; Nitrites; Nitrosamines; Oxidative Stress; Reactive Oxygen Species; Time Factors | 2010 |
Estrogen suppresses metastasis in rat hepatocellular carcinoma through decreasing interleukin-6 and hepatocyte growth factor expression.
Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Estrogens; Ethinyl Estradiol; Female; Hepatocyte Growth Factor; Interleukin-6; Liver Neoplasms, Experimental; Lung Neoplasms; Nitrosamines; Ovariectomy; Rats; Rats, Sprague-Dawley; Tumor Microenvironment | 2012 |
Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glycogen; Insulin Receptor Substrate Proteins; Male; MAP Kinase Kinase 1; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, Insulin; Up-Regulation | 2011 |
Ultrasonographic evidence of phenotypic instability during hepatocarcinogenesis in N-nitrosomorpholine-treated rats.
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Disease Models, Animal; Fibrosis; Image Processing, Computer-Assisted; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Rats; Rats, Sprague-Dawley; Ultrasonography | 2002 |
Hepatotoxin N-nitrosomorpholine-induced carcinogenesis in rat liver: ex vivo exploration of preneoplastic and neoplastic hepatocytes.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hepatocytes; Hot Temperature; Liver Neoplasms; Neoplasm Transplantation; Nitrosamines; Oligonucleotide Array Sequence Analysis; Rats; Signal Transduction; Telomerase; Telomere | 2003 |
Protein phosphatase inhibitor-1 mRNA expression correlates with neoplastic transformation of epithelial liver cells and progression of hepatocellular carcinomas.
Topics: Administration, Oral; Animals; Carcinoma, Hepatocellular; Carrier Proteins; Cell Transformation, Neoplastic; Disease Progression; Epithelial Cells; Gene Expression Regulation, Neoplastic; Intracellular Signaling Peptides and Proteins; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine.
Topics: Alkylating Agents; Animals; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Metastasis; Nitrosamines; Rats; Rats, Inbred F344; Survival | 2005 |
Reduction of genotoxic effects of N-nitrosomorpholine in human hepatoma cells and hamster lung cells by carboxymethyl chitin-glucan.
Topics: Animals; Antimutagenic Agents; Carcinoma, Hepatocellular; Cell Line; Chitin; Chromosome Aberrations; Cricetinae; DNA Damage; Glucans; Humans; Liver Neoplasms; Lung; Mutagens; Nitrosamines; Tumor Cells, Cultured | 2008 |
[Ultrastructure of human hepatic carcinomas compared with ultrastructural findings in hepatomas induced by chemical agents in Wistar rats and the golden hamster].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Cricetinae; Diethylnitrosamine; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mesocricetus; Nitrosamines; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains | 1983 |
Alpha-fetoprotein: cellular origin of a biological marker in rat liver under various experimental conditions.
Topics: alpha-Fetoproteins; Animals; Carbon Tetrachloride Poisoning; Carcinoma, Hepatocellular; Liver; Liver Neoplasms; Liver Regeneration; Male; Mice; Microscopy, Electron; Nitrosamines; Rats | 1981 |
Isoenzyme shift from glucokinase to hexokinase is not an early but a late event in hepatocarcinogenesis.
Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Glucokinase; Hexokinase; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors | 1993 |
Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Genes, p53; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mutation; Nitrosamines; Oncogenes; Rats; Rats, Inbred F344; RNA, Messenger | 1997 |
Ha-ras mutations in N-nitrosomorpholine-induced lesions and inhibition of hepatocarcinogenesis by antisense sequences in rat liver.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Evaluation Studies as Topic; Genes, ras; Injections, Intraperitoneal; Liver Neoplasms; Male; Mutation; Nitrosamines; Oligonucleotides, Antisense; Point Mutation; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1997 |
Enhancement and phenotypic modulation of N-nitrosomorpholine-induced hepatocarcinogenesis by dehydroepiandrosterone.
Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Drug Synergism; Female; Incidence; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Rats; Rats, Sprague-Dawley; Statistics as Topic | 1997 |
Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone.
Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Female; Glycogen; Immunohistochemistry; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Nitrosamines; Phosphoproteins; Precancerous Conditions; Rats; Rats, Sprague-Dawley | 1999 |
Establishment of an in vivo highly metastatic rat hepatocellular carcinoma model.
Topics: Animals; Cadherins; Carcinogens; Carcinoma, Hepatocellular; Diethylnitrosamine; Disease Models, Animal; Immunohistochemistry; Liver Neoplasms; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred F344 | 1999 |
In vivo electroporetic transfer of bcl-2 antisense oligonucleotide inhibits the development of hepatocellular carcinoma in rats.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Northern; Carcinogens; Carcinoma, Hepatocellular; Drug Carriers; Drug Delivery Systems; Liposomes; Liver Neoplasms; Male; Nitrosamines; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2000 |
Transfer of bcl-xs plasmid is effective in preventing and inhibiting rat hepatocellular carcinoma induced by N-nitrosomorpholine.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Electroporation; Gene Expression; Genetic Therapy; Injections, Intralesional; Liposomes; Liver Neoplasms, Experimental; Male; Nitrosamines; Plasmids; Precancerous Conditions; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2001 |
The effect of estradiol-17-phenylpropionate and estradiol benzoate on N-nitrosomorpholine-induced liver carcinogenesis in ovariectomized female rats.
Topics: Animals; Carcinoma, Hepatocellular; Castration; Contraceptives, Oral; Drug Synergism; Estradiol; Female; Liver Neoplasms; Morpholines; Neoplasms, Experimental; Nitrosamines; Ovary; Rats | 1978 |
Inhibition by xiao-chai-hu-tang (TJ-9) of development of hepatic foci induced by N-nitrosomorpholine in Sprague-Dawley rats.
Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Drugs, Chinese Herbal; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Lymphocytes, Tumor-Infiltrating; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred Strains; T-Lymphocytes, Helper-Inducer | 1991 |