Compounds > n-nitrosomorpholine
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n-nitrosomorpholine and Experimental Hepatoma

n-nitrosomorpholine has been researched along with Experimental Hepatoma in 89 studies

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-199029 (32.58)18.7374
1990's38 (42.70)18.2507
2000's16 (17.98)29.6817
2010's5 (5.62)24.3611
2020's1 (1.12)2.80

Authors

AuthorsStudies
Feng, X; Hou, J; Liu, SF; Song, L; Zhang, HL; Zhang, JG; Zheng, L1
Böhning, E; Calvisi, DF; Cigliano, A; Dombrowski, F; Evert, M; Günther, J; Merz, J; Peters, K; Pilo, MG; Ribback, S; Sailer, V; Steinmüller, F; Utpatel, K1
Ahr, HJ; Bannasch, P; Ellinger-Ziegelbauer, H; Glückmann, M; Gundert-Remy, U; Hellmann, J; Ittrich, C; Kiss, E; Kopp-Schneider, A; Kramer, PJ; Krause, E; Kröger, M; Oberemm, A; Richter-Reichhelm, HB; Scholz, G; Seemann, K; Weimer, M1
Groos, J; Kopp-Schneider, A2
Chen, H; Han, SJ; Jia, WD; Liu, WB; Ren, WH; Wang, W; Wang, YC; Xu, GL; Zhang, CH1
Harada, K; Matsui, O; Tsuda, N1
Birth, M; Calvisi, DF; Cigliano, A; Dombrowski, F; Heidecke, CD; Peters, M; Rausch, J; Ribback, S; Sailer, V1
Hwang, TH; Jeong, JS; Kim, YH; Kim, YJ; Kwon, EY; Nam, KJ; Oh, JY; Park, BH1
Futakuchi, M; Ogawa, K; Shirai, T; Takahashi, S; Tamano, S1
Aleem, E; Bannasch, P; Flohr, T; Mayer, D; Thielmann, HW1
Fella, K; Glückmann, M; Hellmann, J; Karas, M; Kramer, PJ; Kröger, M1
Drucker, C; Ellinger, A; Grasl-Kraupp, B; Grusch, M; Parzefall, W; Schulte-Hermann, R; Teufelhofer, O1
Beyer, S; Hellmann, J; Ittrich, C; Kopp-Schneider, A; Kramer, PJ; Kroeger, M; Walter, Y1
Kuhlmann, WD; Peschke, P1
Baba, M; Iishi, H; Nakaizumi, A; Sakai, N; Tatsuta, M; Uehara, H; Yano, H1
Llombart Bosch, A; Peydro Olaya, A1
Guenthner, TM; Krischan, R; Kuhlmann, WD; Kunz, W; Oesch, F1
Bannasch, P; Hacker, HJ; Kunz, HW; Moore, MA1
de Gerlache, J; Lans, M; Préat, V; Roberfroid, M; Taper, H3
Kuhlmann, M; Kuhlmann, WD1
Bannasch, P; Hacker, HJ; Mayer, D; Moore, MA1
Bannasch, P; Hacker, HJ; Klimek, F; Mayer, D1
Althoff, J; Holste, J; Ketkar, MB; Preussmann, R1
Bannach, P; Enzmann, H; Kopp-Schneider, A; Löser, E; Zerban, H1
Bomhard, EM; Enzmann, H; Rosenbruch, M; Wirnitzer, U1
Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H7
Bannasch, P; Kopp-Schneider, A; Radig, S; Zerban, H1
Bannasch, P; Weber, E3
Ruan, YB; Wu, ZB1
Futakuchi, M; Hasegawa, R; Hirose, M; Ito, N; Lijinsky, W; Shirai, T1
Baba, M; Iishi, H; Iseki, K; Nakaizumi, A; Tatsuta, M; Uehara, H; Yano, H2
Futakuchi, M; Imai, T; Inada, K; Masui, T; Mizoguchi, Y; Nakanishi, H; Shirai, T; Tatematsu, M; Yada, H1
Bannasch, P; Klimek, F; Mayer, D; Rempel, A1
Baba, M; Iishi, H; Iseki, K; Nakaizumi, A; Tatsuta, M; Uehara, H; Yamamoto, R; Yano, H1
de Gunst, MC; Luebeck, EG1
Bannasch, P; Klimek, F; Mayer, D1
Bannasch, P; Mayer, D; Metzger, C1
Bannasch, P; Klimek, F; Kopp-Schneider, A; Ströbel, P; Zerban, H1
Bugajska-Schretter, A; Grasl-Kraupp, B; Löw-Baselli, A; Weşierska-Gadek, J1
Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D1
Enzmann, H; Löser, E; Schlüter, G; Wiemann, C1
Baba, M; Iishi, H; Narahara, H; Sakai, N; Tatsuta, M; Yano, H1
de Gunst, M; Grasl-Kraupp, B; Löw-Baselli, A; Luebeck, G; Moolgavkar, S; Schulte-Hermann, R; Wagner, A; Waldhör, T1
Bukowska, K; Grasl-Kraupp, B; Huber, WW; Käfer, M; Löw-Baselli, A; Schulte-Hermann, R1
Fukushima, S; Iwai, S; Morimura, K; Nomura, T; Takayama, R; Wanibuchi, H; Wei, M; Yamamoto, S1
Fukushima, S; Hosono, M; Iwakura, Y; Makino, S; Mori, S; Murai, T; Oohara, T; Takashima, A; Takeda, R1
Baba, M; Iishi, H; Tatsuta, M2
Dimitrijevic, N; Jungblut, PR; Klugbauer, S; Lamer, S; Rabes, HM; Zeindl-Eberhart, E1
Bannasch, P; Pekel, E; Schiebel, K; Stumpf, H; Zerban, H1
Bannasch, P; Hacker, HJ; Ruan, YB1
Bursch, W; Gerbracht, U; Kraus, P; Putz, B; Reinacher, M; Schulte-Hermann, R; Timmermann-Trosiener, I1
Luebeck, EG; Moolgavkar, SH2
Baba, M; Iishi, H; Tatsuta, M; Yamamoto, R1
Cortinovis, C; Klimek, F; Nogueira, E1
Efferth, T; Mattern, J; Volm, M; Zerban, H1
de Gunst, M; Luebeck, EG; Moolgavkar, SH; Port, RE; Schwarz, M1
Bannasch, P; Klimek, F2
Bock, KW; Fischer, G; Kobusch, AB1
Baba, M; Iishi, H; Tatsuta, M; Wada, A; Yamamoto, R1
Bannasch, P; Dettler, T; Enzmann, H; Ohlhauser, D2
Chung, FL; Hecht, SS; Kovatch, RM; Lijinsky, W; Saavedra, JE1
Bock, KW; Münzel, P1
Bock, KW; Fischer, G; Ulrich, D1
Bock, KW; Fischer, G; Lilienblum, W; Ullrich, D1
Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I1
Boix, J; Callaghan, R; Gil, R; Llombart-Bosch, A; Pellin, A1
Ruan, YB1
Bannasch, P; Moore, MA; Weber, E1
Kovatch, RM; Lijinsky, W1
Ruan, YB; Wu, ZB; Zheng, QP1
Kovatch, RM; Lijinsky, W; Riggs, CW; Walters, PT1
Bannasch, P; Enzmann, H1
Bannasch, P; Edler, L; Enzmann, H1

Reviews

2 review(s) available for n-nitrosomorpholine and Experimental Hepatoma

ArticleYear
Hexokinase expression in liver preneoplasia and neoplasia.
    Biochemical Society transactions, 1997, Volume: 25, Issue:1

    Topics: Animals; Carcinogens; Carcinoma; Glucokinase; Hexokinase; Isoenzymes; Kinetics; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats

1997
Stochastic description of initiation and promotion in experimental carcinogenesis.
    Annali dell'Istituto superiore di sanita, 1991, Volume: 27, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Carcinogenicity Tests; Cocarcinogenesis; Liver; Liver Neoplasms, Experimental; Models, Biological; Nitrosamines; Rats; Stochastic Processes

1991

Other Studies

87 other study(ies) available for n-nitrosomorpholine and Experimental Hepatoma

ArticleYear
Establishment of rat liver cancer cell lines with different metastatic potential.
    Scientific reports, 2020, 05-20, Volume: 10, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Diethylnitrosamine; Disease Models, Animal; Karyotyping; Liver Neoplasms, Experimental; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Nitrosamines; Rats

2020
The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models.
    International journal of molecular sciences, 2016, Sep-23, Volume: 17, Issue:10

    Topics: Animals; Cell Proliferation; Disease Models, Animal; Drug Administration Schedule; ErbB Receptors; Female; Gefitinib; Immunohistochemistry; Islets of Langerhans Transplantation; Liver Neoplasms, Experimental; Male; Nitrosamines; Protein Kinase Inhibitors; Quinazolines; ras Proteins; Rats; Rats, Inbred Lew; Sodium-Glucose Transporter 1; Thyroid Epithelial Cells; TOR Serine-Threonine Kinases; Transforming Growth Factor alpha

2016
Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters.
    Toxicology and applied pharmacology, 2009, Dec-01, Volume: 241, Issue:2

    Topics: Animals; Biomarkers, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Proteomics; Rats; Rats, Wistar; Toxicogenetics

2009
Application of a two-phenotype color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment.
    Mathematical biosciences, 2010, Volume: 224, Issue:2

    Topics: Algorithms; Animals; Carcinogens; Cell Proliferation; Color; Hepatocytes; Likelihood Functions; Liver; Liver Neoplasms, Experimental; Male; Models, Biological; Nitrosamines; Phenotype; Rats; Staining and Labeling

2010
Estrogen suppresses metastasis in rat hepatocellular carcinoma through decreasing interleukin-6 and hepatocyte growth factor expression.
    Inflammation, 2012, Volume: 35, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Diethylnitrosamine; Estrogens; Ethinyl Estradiol; Female; Hepatocyte Growth Factor; Interleukin-6; Liver Neoplasms, Experimental; Lung Neoplasms; Nitrosamines; Ovariectomy; Rats; Rats, Sprague-Dawley; Tumor Microenvironment

2012
Effect of change in transporter expression on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging during hepatocarcinogenesis in rats.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:3

    Topics: Analysis of Variance; Animals; ATP-Binding Cassette Transporters; Contrast Media; Disease Progression; Gadolinium DTPA; Hyperplasia; Lasers; Liver; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Magnetic Resonance Imaging; Male; Microdissection; Nitrosamines; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Thioacetamide; Time Factors

2011
Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis.
    Journal of hepatology, 2013, Volume: 58, Issue:6

    Topics: Animals; Cell Proliferation; Fatty Acids; Female; Humans; Lipogenesis; Liver; Liver Neoplasms, Experimental; Male; MAP Kinase Signaling System; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew; TOR Serine-Threonine Kinases

2013
Ultrasonographic evidence of phenotypic instability during hepatocarcinogenesis in N-nitrosomorpholine-treated rats.
    Experimental and molecular pathology, 2002, Volume: 73, Issue:1

    Topics: Animals; Ascites; Carcinoma, Hepatocellular; Disease Models, Animal; Fibrosis; Image Processing, Computer-Assisted; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Rats; Rats, Sprague-Dawley; Ultrasonography

2002
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma.
    Cancer science, 2004, Volume: 95, Issue:1

    Topics: Acetylcysteine; Animals; Aspirin; Blotting, Western; Carcinogens; Diethylnitrosamine; E-Selectin; Enzyme Inhibitors; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasm Metastasis; NF-kappa B; Nitrosamines; Pentoxifylline; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Cell Adhesion Molecule-1

2004
Protein phosphatase inhibitor-1 mRNA expression correlates with neoplastic transformation of epithelial liver cells and progression of hepatocellular carcinomas.
    International journal of oncology, 2004, Volume: 24, Issue:4

    Topics: Administration, Oral; Animals; Carcinoma, Hepatocellular; Carrier Proteins; Cell Transformation, Neoplastic; Disease Progression; Epithelial Cells; Gene Expression Regulation, Neoplastic; Intracellular Signaling Peptides and Proteins; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Sprague-Dawley; RNA, Messenger

2004
Use of two-dimensional gel electrophoresis in predictive toxicology: identification of potential early protein biomarkers in chemically induced hepatocarcinogenesis.
    Proteomics, 2005, Volume: 5, Issue:7

    Topics: Animals; Biomarkers, Tumor; Electrophoresis, Gel, Two-Dimensional; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Nitrosamines; Predictive Value of Tests; Proteins; Rats; Rats, Wistar

2005
Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis.
    Carcinogenesis, 2006, Volume: 27, Issue:1

    Topics: Animals; Carcinogens; Cell Proliferation; Cells, Cultured; DNA; DNA Replication; Epidermal Growth Factor; Fibroblast Growth Factor 7; Glutathione S-Transferase pi; Heparin-binding EGF-like Growth Factor; Hepatocyte Growth Factor; Hepatocytes; Intercellular Signaling Peptides and Proteins; Interleukin-6; Lipopolysaccharides; Liver; Liver Neoplasms, Experimental; Male; Neoplasm Staging; Nitrosamines; Rats; Rats, Wistar; Superoxides; Tumor Necrosis Factor-alpha

2006
Comparison of software tools to improve the detection of carcinogen induced changes in the rat liver proteome by analyzing SELDI-TOF-MS spectra.
    Journal of proteome research, 2006, Volume: 5, Issue:2

    Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Models, Theoretical; Nitrosamines; Proteome; Rats; Rats, Wistar; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2006
Application of a color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment.
    Mathematical biosciences, 2006, Volume: 202, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cell Transformation, Neoplastic; Glutathione S-Transferase pi; Hepatocytes; Histocytochemistry; Liver Neoplasms, Experimental; Male; Models, Biological; Nitrosamines; Phenobarbital; Rats; Rats, Wistar

2006
Hepatic progenitor cells, stem cells, and AFP expression in models of liver injury.
    International journal of experimental pathology, 2006, Volume: 87, Issue:5

    Topics: alpha-Fetoproteins; Animals; Carbon Tetrachloride; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Galactosamine; Hepatectomy; Hepatocytes; Liver Diseases; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Nitrosamines; Rats; Stem Cells

2006
Chemoprevention by amiloride against experimental hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    Cancer letters, 1997, Oct-28, Volume: 119, Issue:1

    Topics: Amiloride; Animals; Antineoplastic Agents; Carcinogens; Cell Proliferation; Chemoprevention; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Sprague-Dawley

1997
[Ultrastructure of human hepatic carcinomas compared with ultrastructural findings in hepatomas induced by chemical agents in Wistar rats and the golden hamster].
    Revista espanola de oncologia, 1983, Volume: 30, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma, Bile Duct; Animals; Carcinoma, Hepatocellular; Cricetinae; Diethylnitrosamine; Female; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mesocricetus; Nitrosamines; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains

1983
Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis.
    Biochemical and biophysical research communications, 1981, Jan-30, Volume: 98, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Epoxide Hydrolases; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Microsomes, Liver; Nitrosamines; Precancerous Conditions; Rabbits; Rats

1981
Enhancement of NNM-induced carcinogenesis in the rat liver by phenobarbital: a combined morphological and enzyme histochemical approach.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Acyltransferases; Animals; Carcinogens; Cell Transformation, Neoplastic; Drug Synergism; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Transglutaminases

1983
[Comparative systemic analysis of experimental models of chemical hepatic carcinogenesis in the rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1984, Volume: 178, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Inbred Strains

1984
Comparison of different models of rat liver carcinogenesis: conclusions from a systemic analysis.
    Toxicologic pathology, 1984, Volume: 12, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Diet; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Models, Biological; Nitrosamines; Phenobarbital; Rats; Rats, Inbred Strains

1984
Immunohistological localization of alpha 1-fetoprotein in normal and diseased liver.
    Acta histochemica. Supplementband, 1982, Volume: 25

    Topics: alpha-Fetoproteins; Animals; Animals, Newborn; Carbon Tetrachloride Poisoning; Carcinogens; Immunoenzyme Techniques; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred Strains; Nitrosamines; Rats; Rats, Inbred Strains

1982
Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver.
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: Animals; Carcinogens; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glyceraldehyde-3-Phosphate Dehydrogenases; Histocytochemistry; Liver; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1982
Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Carcinogens; Cell Transformation, Neoplastic; Glucosephosphate Dehydrogenase; Glycogen Storage Disease; Humans; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1984
Carcinogenic effect of nitrosomorpholine administered in the drinking water to Syrian golden hamsters.
    Cancer letters, 1983, Volume: 17, Issue:3

    Topics: Animals; Carcinogens; Cricetinae; Digestive System Neoplasms; Female; Lethal Dose 50; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Respiratory Tract Neoplasms; Sex Factors; Water

1983
Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis.
    Carcinogenesis, 1995, Volume: 16, Issue:7

    Topics: Animals; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley

1995
Accumulation of p53 protein in chemically induced oval cells during early stages of rodent hepatocarcinogenesis.
    Carcinogenesis, 1995, Volume: 16, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Cell Division; Gene Expression; Genes, p53; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Wistar; Tumor Suppressor Protein p53

1995
Inhibition by somatostatin of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    Carcinogenesis, 1993, Volume: 14, Issue:12

    Topics: Animals; Body Weight; Carcinogens; gamma-Glutamyltransferase; Gastrins; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Organ Size; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Somatostatin

1993
Cell proliferation and cell death (apoptosis) in hepatic preneoplasia and neoplasia are closely related to phenotypic cellular diversity and instability.
    Carcinogenesis, 1994, Volume: 15, Issue:11

    Topics: Animals; Apoptosis; Cell Division; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thymidine

1994
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1994
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiments by oral exposure to N-nitrosomorpholine.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1994
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholine.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1994
Inhibition by verapamil of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    British journal of cancer, 1993, Volume: 68, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Body Weight; Carcinogens; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Organ Size; Rats; Rats, Sprague-Dawley; Verapamil

1993
Inhibition by shi-quan-da-bu-tang (TJ-48) of experimental hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:1

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Drugs, Chinese Herbal; Liver; Liver Neoplasms, Experimental; Male; Mitotic Index; Nitrosamines; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2

1994
[Study on the relationship between most cells and tumor growth speed during hepatocarcinogenesis in the rats].
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1993, Volume: 13, Issue:2

    Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Mast Cells; Nitrosamines; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Silver Staining

1993
Enhancement by isoproterenol of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    International journal of cancer, 1993, Feb-20, Volume: 53, Issue:4

    Topics: Animals; Body Weight; Carcinogens; Cyclic AMP; DNA, Neoplasm; Isoproterenol; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Nitrosamines; Organ Size; Rats; Rats, Sprague-Dawley

1993
Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat.
    Cancer letters, 1996, Sep-10, Volume: 106, Issue:2

    Topics: Animals; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Nitroso Compounds; Precancerous Conditions; Rats; Rats, Inbred F344

1996
Inhibition by the calmodulin antagonist trifluoperazine of experimental hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    Cancer letters, 1996, Oct-22, Volume: 107, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Drug Screening Assays, Antitumor; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Sprague-Dawley; Trifluoperazine

1996
Enhancement by neurotensin of hepatocarcinogenesis by N-nitrosomorpholine in Sprague-Dawley rats.
    Cancer letters, 1996, Dec-20, Volume: 110, Issue:1-2

    Topics: Animals; Carcinogens; Drug Synergism; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Neurotensin; Nitrosamines; Rats; Rats, Sprague-Dawley

1996
Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes.
    Cancer letters, 1997, Jan-15, Volume: 112, Issue:1

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Genes, p53; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mutation; Nitrosamines; Oncogenes; Rats; Rats, Inbred F344; RNA, Messenger

1997
Enhancement by ethyl alcohol of experimental hepatocarcinogenesis induced by N-nitrosomorpholine.
    International journal of cancer, 1997, Jun-11, Volume: 71, Issue:6

    Topics: Animals; Apoptosis; Body Weight; Carcinogens; Ethanol; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Organ Size; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley

1997
Suppression by pravastatin, an inhibitor of p21ras isoprenylation, of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    British journal of cancer, 1998, Volume: 77, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Apoptosis; Blotting, Western; Carcinogens; Cholesterol; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Nitrosamines; Pravastatin; ras Proteins; Rats; Rats, Sprague-Dawley

1998
A method for parametric estimation of the number and size distribution of cell clusters from observations in a section plane.
    Biometrics, 1998, Volume: 54, Issue:1

    Topics: Algorithms; Animals; Biometry; Carcinogens; Cell Count; Cell Division; Cocarcinogenesis; Likelihood Functions; Liver; Liver Neoplasms, Experimental; Male; Models, Biological; Nitrosamines; Precancerous Conditions; Rats; Rats, Wistar; Stochastic Processes

1998
Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells.
    Microscopy research and technique, 1998, Mar-15, Volume: 40, Issue:6

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Enzyme Activation; Glucagon; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Substrate Specificity; Time Factors

1998
Enhancement and phenotypic modulation of N-nitrosomorpholine-induced hepatocarcinogenesis by dehydroepiandrosterone.
    Cancer letters, 1997, Dec-23, Volume: 121, Issue:2

    Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Drug Synergism; Female; Incidence; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Rats; Rats, Sprague-Dawley; Statistics as Topic

1997
Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine.
    Carcinogenesis, 1998, Volume: 19, Issue:12

    Topics: Animals; Carcinogens; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1998
Cleavage of poly(ADP-ribose) transferase during p53-independent apoptosis in rat liver after treatment with N-nitrosomorpholine and cyproterone acetate.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:4

    Topics: Animals; Apoptosis; Carcinogens; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyproterone Acetate; DNA Replication; Female; Gene Expression Regulation; Genes, p53; Glycoside Hydrolases; Granzymes; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Mitogens; Necrosis; Nitrosamines; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Recombinant Fusion Proteins; Serine Endopeptidases; Specific Pathogen-Free Organisms; Testis; Tumor Suppressor Protein p53

1999
Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone.
    Cancer letters, 1999, Jun-01, Volume: 140, Issue:1-2

    Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Female; Glycogen; Immunohistochemistry; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Nitrosamines; Phosphoproteins; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1999
Nonlinearity of nuclear enlargement in hepatocytes induced by the carcinogen N'-nitrosomorpholine in Ovo.
    Cancer detection and prevention, 1999, Volume: 23, Issue:6

    Topics: Animals; Carcinogens; Cell Count; Cell Nucleus; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; Nitrosamines; Ovum; Turkeys

1999
Suppression by Chai-hu-gui-zhi-tang of the development of liver lesions induced by N-nitrosomorpholine in Sprague-Dawley rats.
    Cancer letters, 2000, Apr-28, Volume: 152, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Division; Drugs, Chinese Herbal; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Sprague-Dawley

2000
Quantitative analysis of tumor initiation in rat liver: role of cell replication and cell death (apoptosis).
    Carcinogenesis, 2000, Volume: 21, Issue:7

    Topics: Animals; Apoptosis; Body Weight; Carcinogens; Cell Cycle; Cell Division; Cell Size; Clone Cells; DNA, Neoplasm; Eating; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Models, Biological; Nitrosamines; Organ Size; Rats; Rats, Wistar

2000
Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note.
    Carcinogenesis, 2000, Volume: 21, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Carcinogens; Cell Division; DNA; Eating; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Monoterpenes; Nitrosamines; Phenobarbital; Precancerous Conditions; Proteins; Rats; Rats, Wistar; Terpenes

2000
Chemopreventive effects of S-methylcysteine on rat hepatocarcinogenesis induced by concurrent administration of sodium nitrite and morpholine.
    Cancer letters, 2000, Dec-08, Volume: 161, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Cysteine; Drug Interactions; Food Preservatives; Gastric Mucosa; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Morpholines; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Sodium Nitrite

2000
Induction of hepatocellular carcinoma with high metastatic potential in WS/Shi rats: discovery of an inbred strain highly susceptible to the liver carcinogen N-nitrosomorpholine.
    Oncology research, 2000, Volume: 12, Issue:3

    Topics: Animals; Carcinogens; Disease Susceptibility; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred F344; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity

2000
Transfer of bcl-xs plasmid is effective in preventing and inhibiting rat hepatocellular carcinoma induced by N-nitrosomorpholine.
    Gene therapy, 2001, Volume: 8, Issue:15

    Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Electroporation; Gene Expression; Genetic Therapy; Injections, Intralesional; Liposomes; Liver Neoplasms, Experimental; Male; Nitrosamines; Plasmids; Precancerous Conditions; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger

2001
Proteome analysis of rat hepatomas: carcinogen-dependent tumor-associated protein variants.
    Electrophoresis, 2001, Volume: 22, Issue:14

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Diethylnitrosamine; Electrophoresis, Gel, Two-Dimensional; Fetal Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Inactivation, Metabolic; Isoenzymes; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Molecular Sequence Data; Nafenopin; Neoplasm Proteins; Nitrosamines; Organ Specificity; Peroxisome Proliferators; Proteome; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Subtraction Technique

2001
Altered transferrin gene expression in preneoplastic and neoplastic liver lesions induced in rats with N-nitrosomorpholine.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1992, Volume: 62, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; DNA; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; In Situ Hybridization; Iron; Liver Diseases; Liver Glycogen; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Neoplasm; Transferrin

1992
[The phenotype of mast cells in primary adenoid liver tumours of rats and its relation to tumor cells].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1992, Volume: 21, Issue:1

    Topics: Animals; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Mast Cells; Microscopy, Electron; Nitrosamines; Phenotype; Rats; Rats, Inbred Strains

1992
Inhibition by xiao-chai-hu-tang (TJ-9) of development of hepatic foci induced by N-nitrosomorpholine in Sprague-Dawley rats.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:9

    Topics: Animals; Antineoplastic Agents; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Drugs, Chinese Herbal; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Lymphocytes, Tumor-Infiltrating; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred Strains; T-Lymphocytes, Helper-Inducer

1991
Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Animals; Body Weight; Carcinogens; Cell Survival; Clofibrate; Cyproterone; Cyproterone Acetate; Female; Glutathione Transferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Nafenopin; Nitrosamines; Organ Size; Phenobarbital; Phenotype; Precancerous Conditions; Propionates; Rats; Rats, Inbred Strains

1990
Stochastic analysis of intermediate lesions in carcinogenesis experiments.
    Risk analysis : an official publication of the Society for Risk Analysis, 1991, Volume: 11, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Carcinogens; Cell Division; Female; Liver Neoplasms, Experimental; Models, Biological; Models, Statistical; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew; Stochastic Processes

1991
Inhibition by retinoic acid of hepatocarcinogenesis induced by N-nitrosomorpholine and of expression of myc oncogene protein in Sprague-Dawley rats.
    International journal of cancer, 1991, Sep-30, Volume: 49, Issue:3

    Topics: Animals; Carcinogens; Liver Neoplasms, Experimental; Male; Mice; Nitrosamines; Organ Size; Proto-Oncogene Proteins c-myc; Tretinoin

1991
Rat hepatocarcinogenesis induced by N-nitrosodiethylamine and N-nitrosomorpholine continuously administered at low doses. From basophilic areas of hepatocytes to hepatocellular tumors.
    The American journal of pathology, 1991, Volume: 139, Issue:5

    Topics: Adenoma; Administration, Oral; Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Esophageal Neoplasms; Glycogen; Histocytochemistry; Incidence; Liver; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Nitrosamines; Papilloma; Rats

1991
Overexpression of P-glycoprotein in rat hepatocellular carcinomas induced with N-nitrosomorpholine.
    Carcinogenesis, 1990, Volume: 11, Issue:1

    Topics: Actins; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinogens; Drug Resistance; Fluorescent Antibody Technique; Gene Expression; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Membrane Glycoproteins; Neoplasm Proteins; Nitrosamines; Rats; Rats, Inbred Lew; Reference Values; Transcription, Genetic

1990
Inhibition by neostigmine of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    British journal of cancer, 1990, Volume: 62, Issue:5

    Topics: Animals; gamma-Glutamyltransferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Neostigmine; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Vagotomy

1990
Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis experiments--I. Single agent regimen.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Liver Neoplasms, Experimental; Mathematics; Models, Biological; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew

1990
Biochemical microanalysis of pyruvate kinase activity in preneoplastic and neoplastic liver lesions induced in rats by N-nitrosomorpholine.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: Animals; Carcinogens; Glycogen; Isoenzymes; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Inbred Strains

1990
Tumor-promoting activity and cytotoxicity of 3,4,3',4'-tetrachlorobiphenyl on N-nitrosomorpholine-induced murine liver foci.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:3

    Topics: Adenoma, Bile Duct; Animals; Carcinogens; Enzyme Induction; Glucose-6-Phosphatase; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Nitrosamines; Polychlorinated Biphenyls; Precancerous Conditions

1989
Role of glucose-6-phosphate dehydrogenase on enhanced proliferation of pre-neoplastic and neoplastic cells in rat liver induced by N-nitrosomorpholine.
    International journal of cancer, 1989, May-15, Volume: 43, Issue:5

    Topics: Animals; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Reference Values

1989
Enhancement of hepatocarcinogenesis in rats by dietary fructose.
    Carcinogenesis, 1989, Volume: 10, Issue:7

    Topics: Animals; Carcinogens; Dietary Carbohydrates; Fructose; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Inbred Strains

1989
Biochemical microanalysis of alpha-glucosidase activity in preneoplastic and neoplastic hepatic lesions induced in rats by N-nitrosomorpholine.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1989, Volume: 57, Issue:4

    Topics: alpha-Glucosidases; Animals; Histocytochemistry; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1989
Inhibition by cysteamine of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    International journal of cancer, 1989, Sep-15, Volume: 44, Issue:3

    Topics: Animals; Cysteamine; DNA; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Liver Neoplasms, Experimental; Male; Nitrosamines; Norepinephrine; Rats; Rats, Inbred Strains

1989
Comparative tumorigenicity of N-nitroso-2-hydroxymorpholine, N-nitrosodiethanolamine and N-nitrosomorpholine in A/J mice and F344 rats.
    Carcinogenesis, 1989, Volume: 10, Issue:8

    Topics: Adenocarcinoma; Animals; Carcinogens; Diethylnitrosamine; Female; Hemangiosarcoma; Liver Neoplasms; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred A; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Species Specificity; Structure-Activity Relationship; Thyroid Neoplasms

1989
Hypomethylation of c-myc proto-oncogene of N-nitrosomorpholine--induced rat liver nodules and of H4IIE cells.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1989, Volume: 13

    Topics: Animals; Cells, Cultured; Cytosine; DNA; Liver; Liver Neoplasms, Experimental; Male; Methylation; Nitrosamines; Phosphorus Radioisotopes; Proto-Oncogenes; Rats; Rats, Inbred Strains

1989
Effects of N-nitrosomorpholine and phenobarbital on UDP-glucuronyltransferase in putative preneoplastic foci of rat liver.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Aryl Hydrocarbon Hydroxylases; gamma-Glutamyltransferase; Glucuronosyltransferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1985
Immunohistochemical differentiation of gamma-glutamyltranspeptidase in focal lesions and in zone I of rat liver after treatment with chemical carcinogens.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: 2-Acetylaminofluorene; Animals; Female; gamma-Glutamyltransferase; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Methapyrilene; Nitrosamines; Rats; Rats, Inbred Strains

1986
Influence of the nature and the dose of the initiator on the development of premalignant and malignant lesions in rat hepatocarcinogenesis.
    Teratogenesis, carcinogenesis, and mutagenesis, 1986, Volume: 6, Issue:3

    Topics: Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1986
Facilitated expression of adaptive responses to phenobarbital in putative pre-stages of liver cancer.
    Carcinogenesis, 1986, Volume: 7, Issue:10

    Topics: Adaptation, Physiological; Animals; Cytochrome P-450 Enzyme System; DNA; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1986
Morphometric and cytophotometric nuclear analysis of altered hepatocyte foci induced by N-nitrosomorpholine (NNM) and aflatoxin B1 (AFB1) in liver of Wistar rats.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1988, Volume: 54, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1988
[Cytochemical and electron microscopical characteristics of the cellular phenotype of adenoid liver tumors].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1987, Volume: 16, Issue:1

    Topics: Animals; Basement Membrane; Carcinogens; Histocytochemistry; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Rats; Rats, Inbred Strains

1987
Phenotypic modulation of hepatocarcinogenesis and reduction in N-nitrosomorpholine-induced hemangiosarcoma and adrenal lesion development in Sprague-Dawley rats by dehydroepiandrosterone.
    Carcinogenesis, 1988, Volume: 9, Issue:7

    Topics: Adenoma; Adrenal Cortex Diseases; Animals; Dehydroepiandrosterone; Hemangiosarcoma; Liver Neoplasms; Liver Neoplasms, Experimental; Mitotic Index; Nitrosamines; Rats

1988
The effect of age on susceptibility of rats to carcinogenesis by two nitrosamines.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:12

    Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Thyroid Neoplasms

1986
[Observation of mast cells in adenoid liver tumors].
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1988, Volume: 8, Issue:3

    Topics: Animals; Liver Neoplasms, Experimental; Male; Mast Cells; Nitrosamines; Rats; Rats, Inbred Strains

1988
Dose-response study with N-nitrosomorpholine in drinking water of F-344 rats.
    Cancer research, 1988, Apr-15, Volume: 48, Issue:8

    Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Drinking; Female; Liver Neoplasms, Experimental; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344

1988
Non-persisting early foci of altered hepatocytes induced in rats by N-nitrosomorpholine.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:1

    Topics: Animals; Glucosephosphate Dehydrogenase; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1988
Elevation of glucose-6-phosphate in early stages of hepatocarcinogenesis induced in rats by N-nitrosomorpholine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:2

    Topics: Animals; Glucose-6-Phosphate; Glucosephosphates; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Inbred Strains

1988
Simple elementary method for the quantification of focal liver lesions induced by carcinogens.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Time Factors

1987