Compounds > n-nitrosomorpholine
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n-nitrosomorpholine and Condition, Preneoplastic

n-nitrosomorpholine has been researched along with Condition, Preneoplastic in 62 studies

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199025 (40.32)18.7374
1990's27 (43.55)18.2507
2000's8 (12.90)29.6817
2010's2 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahr, HJ; Bannasch, P; Ellinger-Ziegelbauer, H; Glückmann, M; Gundert-Remy, U; Hellmann, J; Ittrich, C; Kiss, E; Kopp-Schneider, A; Kramer, PJ; Krause, E; Kröger, M; Oberemm, A; Richter-Reichhelm, HB; Scholz, G; Seemann, K; Weimer, M1
Aleem, E; Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D1
Birth, M; Calvisi, DF; Cigliano, A; Dombrowski, F; Heidecke, CD; Peters, M; Rausch, J; Ribback, S; Sailer, V1
de Gunst, MC; Dewanji, A; Luebeck, EG1
Dombrowski, F; Evert, M; Jost, CM; Manekeller, S1
Guenthner, TM; Krischan, R; Kuhlmann, WD; Kunz, W; Oesch, F1
Bannasch, P; Hacker, HJ; Kunz, HW; Moore, MA1
Ohde, G; Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I1
Buchmann, A; Kunz, W; Schwarz, M; Wiesbeck, G1
Bannasch, P; Hacker, HJ; Mayer, D; Moore, MA1
Bannasch, P; Hacker, HJ; Klimek, F; Mayer, D1
Roome, N; Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I1
Bannasch, P; Klimek, F; Mayer, D2
de Gerlache, J; Fort, L; Lans, M; Roberfroid, M; Taper, HS1
Bannasch, P; Hacker, HJ; Moore, MA1
Bannasch, P; Benner, U; Hacker, HJ; Klimek, F; Mayer, D; Moore, M; Zerban, H1
Bannasch, P; Mayer, D; Moore, MA1
Bannach, P; Enzmann, H; Kopp-Schneider, A; Löser, E; Zerban, H1
Baba, M; Iishi, H; Nakaizumi, A; Tatsuta, M; Uehara, H2
Bannasch, P; Kopp-Schneider, A; Radig, S; Zerban, H1
Bannasch, P; Weber, E3
Ruan, YB; Wu, ZB1
Bannasch, P; Klimek, F3
Futakuchi, M; Hasegawa, R; Hirose, M; Ito, N; Lijinsky, W; Shirai, T1
Bannasch, P; Klimek, F; Mayer, D; Rempel, A1
Baba, M; Iishi, H; Tatsuta, M; Yamamoto, R1
de Gunst, MC; Luebeck, EG1
Bannasch, P; Klimek, F; Kopp-Schneider, A; Ströbel, P; Zerban, H1
Eigenbrodt, E; Klingelhöffer, A; Oesch, F; Schäfer, A; Steinberg, P; Weisse, G; Wüst, G1
Bannasch, P; Klimek, F; Mayer, D; Nehrbass, D1
Grasl-Kraupp, B; Hufnagl, K; Löw-Baselli, A; Parzefall, W; Schulte-Hermann, R1
Bukowska, K; Grasl-Kraupp, B; Huber, WW; Käfer, M; Löw-Baselli, A; Schulte-Hermann, R1
Fukushima, S; Iwai, S; Morimura, K; Nomura, T; Takayama, R; Wanibuchi, H; Wei, M; Yamamoto, S1
Geisler, I; Kopp-Schneider, A1
Baba, M; Iishi, H; Tatsuta, M1
Bannasch, P; Pekel, E; Schiebel, K; Stumpf, H; Zerban, H1
Enzmann, H; Kaliner, G; Löser, E; Watta-Gebert, B1
Bursch, W; Gerbracht, U; Kraus, P; Putz, B; Reinacher, M; Schulte-Hermann, R; Timmermann-Trosiener, I1
Luebeck, EG; Moolgavkar, SH2
Bock, KW; Dirheimer, G; Keith, G; Münzel, PA; Pfohl-Leszkowicz, A; Röhrdanz, E1
de Gunst, M; Luebeck, EG; Moolgavkar, SH; Port, RE; Schwarz, M1
Barthel, G; Bursch, W; Schulte-Hermann, R; Timmermann-Trosiener, I1
Bannasch, P; Dettler, T; Enzmann, H; Ohlhauser, D; Stumpf, H1
Bock, KW; Fischer, G; Kobusch, AB1
Baba, M; Iishi, H; Tatsuta, M; Wada, A; Yamamoto, R1
Bock, KW; Fischer, G; Ulrich, D1
de Gerlache, J; Lans, M; Préat, V; Roberfroid, M; Taper, H1
Schulte-Hermann, R; Schuppler, J; Timmermann-Trosiener, I1
Bannasch, P; Hacker, HJ; Ito, N; Katayama, H; Masui, T; Tsuda, H1
Bannasch, P; Enzmann, H2
Boix, J; Callaghan, R; Gil, R; Llombart-Bosch, A; Pellin, A1
Bannasch, P; Moore, MA; Weber, E1
Bannasch, P; Ehemann, V; Hacker, HJ; Mayer, D1
Bannasch, P; Edler, L; Enzmann, H1

Reviews

3 review(s) available for n-nitrosomorpholine and Condition, Preneoplastic

ArticleYear
Cytochemical and biochemical microanalysis of carcinogenesis.
    The Histochemical journal, 1981, Volume: 13, Issue:5

    Topics: Animals; Histocytochemistry; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; Microscopy, Electron; Neoplasms; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats

1981
Hexokinase expression in liver preneoplasia and neoplasia.
    Biochemical Society transactions, 1997, Volume: 25, Issue:1

    Topics: Animals; Carcinogens; Carcinoma; Glucokinase; Hexokinase; Isoenzymes; Kinetics; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats

1997
The role of somatic mutations and cell replication kinetics in quantitative cancer risk assessment.
    Progress in clinical and biological research, 1991, Volume: 369

    Topics: Adenosine Triphosphatases; Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Cell Division; Liver; Liver Neoplasms; Mutation; Nitrosamines; Precancerous Conditions; Rats; Risk Factors

1991

Other Studies

59 other study(ies) available for n-nitrosomorpholine and Condition, Preneoplastic

ArticleYear
Toxicogenomic analysis of N-nitrosomorpholine induced changes in rat liver: comparison of genomic and proteomic responses and anchoring to histopathological parameters.
    Toxicology and applied pharmacology, 2009, Dec-01, Volume: 241, Issue:2

    Topics: Animals; Biomarkers, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Humans; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Proteomics; Rats; Rats, Wistar; Toxicogenetics

2009
Upregulation of the insulin receptor and type I insulin-like growth factor receptor are early events in hepatocarcinogenesis.
    Toxicologic pathology, 2011, Volume: 39, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glycogen; Insulin Receptor Substrate Proteins; Male; MAP Kinase Kinase 1; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Receptor, Insulin; Up-Regulation

2011
Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis.
    Journal of hepatology, 2013, Volume: 58, Issue:6

    Topics: Animals; Cell Proliferation; Fatty Acids; Female; Humans; Lipogenesis; Liver; Liver Neoplasms, Experimental; Male; MAP Kinase Signaling System; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew; TOR Serine-Threonine Kinases

2013
Exploring heterogeneity in tumour data using Markov chain Monte Carlo.
    Statistics in medicine, 2003, May-30, Volume: 22, Issue:10

    Topics: Animals; Bayes Theorem; Liver Neoplasms; Markov Chains; Models, Biological; Monte Carlo Method; Nitrosamines; Poisson Distribution; Precancerous Conditions; Rats; Stochastic Processes

2003
Cocarcinogenic effects of islet hormones and N-nitrosomorpholine in hepatocarcinogenesis after intrahepatic transplantation of pancreatic islets in streptozotocin-diabetic rats.
    Cancer research, 2005, Aug-01, Volume: 65, Issue:15

    Topics: Animals; Blood Glucose; Carcinogens; Cocarcinogenesis; Diabetes Mellitus, Experimental; Islets of Langerhans Transplantation; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew

2005
Focal elevation of liver microsomal epoxide hydrolase in early preneoplastic stages and its behaviour in the further course of hepatocarcinogenesis.
    Biochemical and biophysical research communications, 1981, Jan-30, Volume: 98, Issue:2

    Topics: Adenosine Triphosphatases; Animals; Epoxide Hydrolases; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Microsomes, Liver; Nitrosamines; Precancerous Conditions; Rabbits; Rats

1981
Enhancement of NNM-induced carcinogenesis in the rat liver by phenobarbital: a combined morphological and enzyme histochemical approach.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Acyltransferases; Animals; Carcinogens; Cell Transformation, Neoplastic; Drug Synergism; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Transglutaminases

1983
Effect of tumor promoters on proliferation of putative preneoplastic cells in rat liver.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Carcinogens; Cell Division; Cyproterone; Cyproterone Acetate; Eating; Female; Hexachlorocyclohexane; Liver; Liver Neoplasms; Male; Mitotic Index; Nitrosamines; Precancerous Conditions; Progesterone; Rats; Rats, Inbred Strains

1982
Effect of ethanol on early stages in nitrosamine carcinogenesis in rat liver.
    Cancer letters, 1983, Volume: 20, Issue:3

    Topics: Adenosine Triphosphatases; Alcoholism; Animals; Carcinogens; Diethylnitrosamine; Female; Humans; Liver Neoplasms; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1983
Correlative histochemistry of some enzymes of carbohydrate metabolism in preneoplastic and neoplastic lesions in the rat liver.
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: Animals; Carcinogens; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glucosyltransferases; Glyceraldehyde-3-Phosphate Dehydrogenases; Histocytochemistry; Liver; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1982
Hepatocellular glycogenosis and related pattern of enzymatic changes during hepatocarcinogenesis.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Carcinogens; Cell Transformation, Neoplastic; Glucosephosphate Dehydrogenase; Glycogen Storage Disease; Humans; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1984
Immunocytochemical demonstration of a phenobarbital-inducible cytochrome P450 in putative preneoplastic foci of rat liver.
    Carcinogenesis, 1984, Volume: 5, Issue:2

    Topics: Animals; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Histocytochemistry; Liver; Liver Neoplasms; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1984
Biochemical microanalysis of glycogen content and glucose-6-phosphate dehydrogenase activity in focal lesions of the rat liver induced by N-nitrosomorpholine.
    Carcinogenesis, 1984, Volume: 5, Issue:2

    Topics: Animals; Carcinogens; Glucosephosphate Dehydrogenase; Glycogen; Liver; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1984
Morphological alterations and DNase deficiency in phenobarbital promotion of N-nitrosomorpholine initiated rat hepatocarcinogenesis.
    Carcinogenesis, 1983, Volume: 4, Issue:2

    Topics: Animals; Carcinogens; Deoxyribonucleases; Drug Synergism; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1983
Phenotypic instability in focal and nodular lesions induced in a short term system in the rat liver.
    Carcinogenesis, 1983, Volume: 4, Issue:5

    Topics: Animals; Carcinogens; Enzymes; Glycogen; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1983
The dose dependence and sequential appearance of putative preneoplastic populations induced in the rat liver by stop experiments with N-nitrosomorpholine.
    Carcinogenesis, 1982, Volume: 3, Issue:12

    Topics: Animals; Carcinogens; Cell Nucleus; Cytoplasm; Dose-Response Relationship, Drug; Drug Administration Schedule; Liver Glycogen; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1982
Effects of low doses of N-nitrosomorpholine on the development of early stages of hepatocarcinogenesis.
    Carcinogenesis, 1995, Volume: 16, Issue:7

    Topics: Animals; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley

1995
Inhibition by somatostatin of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    Carcinogenesis, 1993, Volume: 14, Issue:12

    Topics: Animals; Body Weight; Carcinogens; gamma-Glutamyltransferase; Gastrins; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Organ Size; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Somatostatin

1993
Cell proliferation and cell death (apoptosis) in hepatic preneoplasia and neoplasia are closely related to phenotypic cellular diversity and instability.
    Carcinogenesis, 1994, Volume: 15, Issue:11

    Topics: Animals; Apoptosis; Cell Division; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Thymidine

1994
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1994
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced in stop experiments by oral exposure to N-nitrosomorpholine.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1994
Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by continuous oral exposure to N-nitrosomorpholine.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1994
[Study on the relationship between most cells and tumor growth speed during hepatocarcinogenesis in the rats].
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1993, Volume: 13, Issue:2

    Topics: Animals; Liver; Liver Neoplasms, Experimental; Male; Mast Cells; Nitrosamines; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Silver Staining

1993
Isoenzyme shift from glucokinase to hexokinase is not an early but a late event in hepatocarcinogenesis.
    Carcinogenesis, 1993, Volume: 14, Issue:9

    Topics: Adenoma, Liver Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Glucokinase; Hexokinase; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Time Factors

1993
Effects of low dose mixtures of four N-nitroso compounds on hepatic foci development in the rat.
    Cancer letters, 1996, Sep-10, Volume: 106, Issue:2

    Topics: Animals; Carcinogens; Diethylnitrosamine; Dimethylnitrosamine; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Nitroso Compounds; Precancerous Conditions; Rats; Rats, Inbred F344

1996
Ha-ras mutations in N-nitrosomorpholine-induced lesions and inhibition of hepatocarcinogenesis by antisense sequences in rat liver.
    International journal of cancer, 1997, Sep-04, Volume: 72, Issue:5

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Evaluation Studies as Topic; Genes, ras; Injections, Intraperitoneal; Liver Neoplasms; Male; Mutation; Nitrosamines; Oligonucleotides, Antisense; Point Mutation; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1997
A method for parametric estimation of the number and size distribution of cell clusters from observations in a section plane.
    Biometrics, 1998, Volume: 54, Issue:1

    Topics: Algorithms; Animals; Biometry; Carcinogens; Cell Count; Cell Division; Cocarcinogenesis; Likelihood Functions; Liver; Liver Neoplasms, Experimental; Male; Models, Biological; Nitrosamines; Precancerous Conditions; Rats; Rats, Wistar; Stochastic Processes

1998
Cytochemical and biochemical studies on adenylate cyclase activity in preneoplastic and neoplastic liver tissue and cultured liver cells.
    Microscopy research and technique, 1998, Mar-15, Volume: 40, Issue:6

    Topics: Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cholera Toxin; Colforsin; Enzyme Activation; Glucagon; Liver; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Microscopy, Phase-Contrast; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Substrate Specificity; Time Factors

1998
Xenomorphic hepatocellular precursors and neoplastic progression of tigroid cell foci induced in rats with low doses of N-nitrosomorpholine.
    Carcinogenesis, 1998, Volume: 19, Issue:12

    Topics: Animals; Carcinogens; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Disease Progression; Dose-Response Relationship, Drug; Immunohistochemistry; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1998
Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats.
    Virchows Archiv : an international journal of pathology, 1999, Volume: 434, Issue:3

    Topics: Animals; Carcinogens; Isoenzymes; Liver; Male; Nitrosamines; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Wistar

1999
Insulin receptor substrate-1 is over-expressed in glycogenotic but not in amphophilic preneoplastic hepatic foci induced in rats by N-nitrosomorpholine and dehydroepiandrosterone.
    Cancer letters, 1999, Jun-01, Volume: 140, Issue:1-2

    Topics: Adenoma, Liver Cell; Animals; Carcinoma, Hepatocellular; Dehydroepiandrosterone; Female; Glycogen; Immunohistochemistry; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Nitrosamines; Phosphoproteins; Precancerous Conditions; Rats; Rats, Sprague-Dawley

1999
Initiated rat hepatocytes in primary culture: a novel tool to study alterations in growth control during the first stage of carcinogenesis.
    Carcinogenesis, 2000, Volume: 21, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Cyproterone Acetate; DNA; Glutathione Transferase; Liver; Liver Neoplasms; Male; Nitrosamines; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Wistar; Transforming Growth Factor beta

2000
Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note.
    Carcinogenesis, 2000, Volume: 21, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Carcinogens; Cell Division; DNA; Eating; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Monoterpenes; Nitrosamines; Phenobarbital; Precancerous Conditions; Proteins; Rats; Rats, Wistar; Terpenes

2000
Chemopreventive effects of S-methylcysteine on rat hepatocarcinogenesis induced by concurrent administration of sodium nitrite and morpholine.
    Cancer letters, 2000, Dec-08, Volume: 161, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Bromodeoxyuridine; Carcinogens; Cell Division; Cysteine; Drug Interactions; Food Preservatives; Gastric Mucosa; Glutathione Transferase; Liver; Liver Neoplasms, Experimental; Male; Morpholines; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Sodium Nitrite

2000
A model for hepatocarcinogenesis with clonal expansion of three successive phenotypes of preneoplastic cells.
    Mathematical biosciences, 2000, Volume: 168, Issue:2

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Likelihood Functions; Liver Neoplasms; Male; Models, Biological; Nitrosamines; Numerical Analysis, Computer-Assisted; Phenotype; Precancerous Conditions; Rats; Rats, Sprague-Dawley

2000
Transfer of bcl-xs plasmid is effective in preventing and inhibiting rat hepatocellular carcinoma induced by N-nitrosomorpholine.
    Gene therapy, 2001, Volume: 8, Issue:15

    Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Electroporation; Gene Expression; Genetic Therapy; Injections, Intralesional; Liposomes; Liver Neoplasms, Experimental; Male; Nitrosamines; Plasmids; Precancerous Conditions; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger

2001
Altered transferrin gene expression in preneoplastic and neoplastic liver lesions induced in rats with N-nitrosomorpholine.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1992, Volume: 62, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; DNA; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; In Situ Hybridization; Iron; Liver Diseases; Liver Glycogen; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Nitrosamines; Precancerous Conditions; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Neoplasm; Transferrin

1992
Foci of altered hepatocytes induced in embryonal turkey liver.
    Carcinogenesis, 1992, Volume: 13, Issue:6

    Topics: Animals; Glucosephosphate Dehydrogenase; Glycogen; Liver; Liver Neoplasms; Nitrosamines; Precancerous Conditions; Turkeys; Urethane

1992
Effects of hypolipidemic drugs nafenopin and clofibrate on phenotypic expression and cell death (apoptosis) in altered foci of rat liver.
    Carcinogenesis, 1990, Volume: 11, Issue:4

    Topics: Animals; Body Weight; Carcinogens; Cell Survival; Clofibrate; Cyproterone; Cyproterone Acetate; Female; Glutathione Transferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Nafenopin; Nitrosamines; Organ Size; Phenobarbital; Phenotype; Precancerous Conditions; Propionates; Rats; Rats, Inbred Strains

1990
Stochastic analysis of intermediate lesions in carcinogenesis experiments.
    Risk analysis : an official publication of the Society for Risk Analysis, 1991, Volume: 11, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Carcinogens; Cell Division; Female; Liver Neoplasms, Experimental; Models, Biological; Models, Statistical; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew; Stochastic Processes

1991
Site-specific hypomethylation of c-myc protooncogene in liver nodules and inhibition of DNA methylation by N-nitrosomorpholine.
    Biochemical pharmacology, 1991, Jul-05, Volume: 42, Issue:2

    Topics: Animals; Deoxycytidine; DNA Modification Methylases; DNA, Bacterial; DNA, Neoplasm; Liver Neoplasms; Male; Methylation; Nitrosamines; Precancerous Conditions; Proto-Oncogenes; Rats; Rats, Inbred Strains; RNA, Neoplasm

1991
Inhibition by neostigmine of hepatocarcinogenesis induced by N-nitrosomorpholine in Sprague-Dawley rats.
    British journal of cancer, 1990, Volume: 62, Issue:5

    Topics: Animals; gamma-Glutamyltransferase; Hepatectomy; Liver Neoplasms, Experimental; Male; Neostigmine; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Vagotomy

1990
Quantitative analysis of enzyme-altered foci in rat hepatocarcinogenesis experiments--I. Single agent regimen.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Liver Neoplasms, Experimental; Mathematics; Models, Biological; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Lew

1990
DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion.
    Cancer research, 1990, Aug-15, Volume: 50, Issue:16

    Topics: Animals; Body Weight; Carcinogens; Cell Division; DNA Replication; Female; Liver; Liver Neoplasms; Nitrosamines; Organ Size; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Inbred Strains; Thymidine

1990
Biochemical microanalysis of pyruvate kinase activity in preneoplastic and neoplastic liver lesions induced in rats by N-nitrosomorpholine.
    Carcinogenesis, 1990, Volume: 11, Issue:8

    Topics: Animals; Carcinogens; Glycogen; Isoenzymes; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Pyruvate Kinase; Rats; Rats, Inbred Strains

1990
Dietary fructose enhances the development of atypical acinar cell nodules in the pancreas of rats pretreated with N-nitrosomorpholine.
    Archiv fur Geschwulstforschung, 1990, Volume: 60, Issue:4

    Topics: Animals; Carcinogens; Carcinoma; Dietary Carbohydrates; Drug Synergism; Fructose; Male; Nitrosamines; Pancreas; Pancreatic Neoplasms; Precancerous Conditions; Rats; Rats, Inbred Strains

1990
Tumor-promoting activity and cytotoxicity of 3,4,3',4'-tetrachlorobiphenyl on N-nitrosomorpholine-induced murine liver foci.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:3

    Topics: Adenoma, Bile Duct; Animals; Carcinogens; Enzyme Induction; Glucose-6-Phosphatase; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Nitrosamines; Polychlorinated Biphenyls; Precancerous Conditions

1989
Role of glucose-6-phosphate dehydrogenase on enhanced proliferation of pre-neoplastic and neoplastic cells in rat liver induced by N-nitrosomorpholine.
    International journal of cancer, 1989, May-15, Volume: 43, Issue:5

    Topics: Animals; gamma-Glutamyltransferase; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Reference Values

1989
Biochemical microanalysis of alpha-glucosidase activity in preneoplastic and neoplastic hepatic lesions induced in rats by N-nitrosomorpholine.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1989, Volume: 57, Issue:4

    Topics: alpha-Glucosidases; Animals; Histocytochemistry; Liver Glycogen; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1989
Effects of N-nitrosomorpholine and phenobarbital on UDP-glucuronyltransferase in putative preneoplastic foci of rat liver.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Aryl Hydrocarbon Hydroxylases; gamma-Glutamyltransferase; Glucuronosyltransferase; Liver Neoplasms, Experimental; Male; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1985
Influence of the nature and the dose of the initiator on the development of premalignant and malignant lesions in rat hepatocarcinogenesis.
    Teratogenesis, carcinogenesis, and mutagenesis, 1986, Volume: 6, Issue:3

    Topics: Animals; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1986
Facilitated expression of adaptive responses to phenobarbital in putative pre-stages of liver cancer.
    Carcinogenesis, 1986, Volume: 7, Issue:10

    Topics: Adaptation, Physiological; Animals; Cytochrome P-450 Enzyme System; DNA; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1986
Correlative histochemical studies on preneoplastic and neoplastic lesions in the kidney of rats treated with nitrosamines.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1986, Volume: 51, Issue:5

    Topics: Animals; Carcinogens; Diethylnitrosamine; Glycolysis; Kidney; Kidney Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1986
Morphometric study of alterations of extrafocal hepatocytes of rat liver treated with N-nitrosomorpholine.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1987, Volume: 53, Issue:4

    Topics: Animals; Carcinogens; Cell Nucleus; Liver; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains; Time Factors

1987
Morphometric and cytophotometric nuclear analysis of altered hepatocyte foci induced by N-nitrosomorpholine (NNM) and aflatoxin B1 (AFB1) in liver of Wistar rats.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1988, Volume: 54, Issue:6

    Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1988
Enzyme histochemical and morphological phenotype of amphophilic foci and amphophilic/tigroid cell adenomas in rat liver after combined treatment with dehydroepiandrosterone and N-nitrosomorpholine.
    Carcinogenesis, 1988, Volume: 9, Issue:6

    Topics: Animals; Carcinogens; Dehydroepiandrosterone; Drug Interactions; Liver; Liver Neoplasms; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1988
Non-persisting early foci of altered hepatocytes induced in rats by N-nitrosomorpholine.
    Journal of cancer research and clinical oncology, 1988, Volume: 114, Issue:1

    Topics: Animals; Glucosephosphate Dehydrogenase; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1988
Loss of adenylate cyclase activity in preneoplastic and neoplastic lesions induced in rat liver by N-nitrosomorpholine.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Adenylyl Cyclase Inhibitors; Animals; Cholera Toxin; Colforsin; Glucagon; Glucosephosphate Dehydrogenase; Liver; Liver Neoplasms; Male; Microscopy, Electron; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred Strains

1986
Simple elementary method for the quantification of focal liver lesions induced by carcinogens.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: Animals; Carcinogens; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Precancerous Conditions; Rats; Time Factors

1987