n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Reperfusion Injury in 4 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Exogenous zinc can protect cardiac cells from reperfusion injury, but the exact roles of endogenous zinc in the pathogenesis of reperfusion injury and in adenosine A(2) receptor activation-induced cardioprotection against reperfusion injury remain unknown." | 7.76 | The critical role of intracellular zinc in adenosine A(2) receptor activation induced cardioprotection against reperfusion injury. ( Chanoit, G; Ghio, AJ; Lee, S; McIntosh, R; Shen, X; Xi, J; Xu, Z; Zhu, M; Zvara, DA, 2010) |
| "Exogenous zinc can protect cardiac cells from reperfusion injury, but the exact roles of endogenous zinc in the pathogenesis of reperfusion injury and in adenosine A(2) receptor activation-induced cardioprotection against reperfusion injury remain unknown." | 3.76 | The critical role of intracellular zinc in adenosine A(2) receptor activation induced cardioprotection against reperfusion injury. ( Chanoit, G; Ghio, AJ; Lee, S; McIntosh, R; Shen, X; Xi, J; Xu, Z; Zhu, M; Zvara, DA, 2010) |
| "Our findings reveal a novel mechanism of cerebral ischemia-induced BBB damage, and implicate zinc as an effective and viable new target for reducing acute BBB damage following ischemic stroke." | 1.43 | Zinc contributes to acute cerebral ischemia-induced blood-brain barrier disruption. ( Dong, W; Ji, X; Liang, J; Liu, KJ; Luo, Y; Pan, R; Qi, Z; Shen, J; Shi, W; Yang, Y; Zhao, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haruta, Y | 1 |
| Kobayakawa, K | 1 |
| Saiwai, H | 1 |
| Hata, K | 1 |
| Tamaru, T | 1 |
| Iura, H | 1 |
| Ono, G | 1 |
| Kitade, K | 1 |
| Kijima, K | 1 |
| Iida, K | 1 |
| Kawaguchi, K | 1 |
| Matsumoto, Y | 1 |
| Kubota, K | 1 |
| Maeda, T | 1 |
| Konno, DJ | 1 |
| Okada, S | 1 |
| Nakashima, Y | 1 |
| Qi, Z | 1 |
| Liang, J | 1 |
| Pan, R | 1 |
| Dong, W | 1 |
| Shen, J | 1 |
| Yang, Y | 1 |
| Zhao, Y | 1 |
| Shi, W | 1 |
| Luo, Y | 1 |
| Ji, X | 1 |
| Liu, KJ | 1 |
| McIntosh, R | 1 |
| Lee, S | 1 |
| Ghio, AJ | 1 |
| Xi, J | 1 |
| Zhu, M | 1 |
| Shen, X | 1 |
| Chanoit, G | 1 |
| Zvara, DA | 1 |
| Xu, Z | 1 |
| Hochhauser, E | 1 |
| Ben-Ari, Z | 1 |
| Pappo, O | 1 |
| Chepurko, Y | 1 |
| Vidne, BA | 1 |
4 other studies available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Reperfusion Injury
| Article | Year |
|---|---|
Zinc chelator treatment in crush syndrome model mice attenuates ischemia-reperfusion-induced muscle injury due to suppressing of neutrophil infiltration.
Topics: Animals; Anti-Inflammatory Agents; Chelating Agents; Chemokines; Crush Syndrome; Cytokines; Ethylene | 2022 |
Zinc contributes to acute cerebral ischemia-induced blood-brain barrier disruption.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Ethylenediamines; Infarction, Middle Cerebral Artery; | 2016 |
The critical role of intracellular zinc in adenosine A(2) receptor activation induced cardioprotection against reperfusion injury.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cytoplasm; Ethylenediamines; Heart; Male; Mem | 2010 |
TPEN attenuates hepatic apoptotic ischemia/ reperfusion injury and remote early cardiac dysfunction.
Topics: Animals; Apoptosis; Caspases; Chelating Agents; Ethylenediamines; Ischemia; Liver; Male; Rats; Rats, | 2005 |