n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Parkinson Disease in 2 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Therefore, total Zn and labile Zn were quantitatively determined in living nematodes as individual biomarkers of Zn uptake and bioavailability with inductively coupled plasma tandem mass spectrometry (ICP-MS/MS) or a multi-well method using the fluorescent probe ZinPyr-1." | 1.51 | Zn homeostasis in genetic models of Parkinson's disease in Caenorhabditis elegans. ( Aschner, M; Baesler, J; Bornhorst, J; Haase, H; Kopp, JF; Pohl, G; Schwerdtle, T, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamano, H | 1 |
| Nishio, R | 1 |
| Morioka, H | 1 |
| Takeda, A | 1 |
| Baesler, J | 1 |
| Kopp, JF | 1 |
| Pohl, G | 1 |
| Aschner, M | 1 |
| Haase, H | 1 |
| Schwerdtle, T | 1 |
| Bornhorst, J | 1 |
2 other studies available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Parkinson Disease
| Article | Year |
|---|---|
Extracellular Zn
Topics: Animals; Calcium; Chelating Agents; Disease Models, Animal; Dopaminergic Neurons; Ethylenediamines; | 2019 |
Zn homeostasis in genetic models of Parkinson's disease in Caenorhabditis elegans.
Topics: Animals; Biological Availability; Biomarkers; Caenorhabditis elegans; Ethylenediamines; Homeostasis; | 2019 |