n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Cerebral Ischemia in 5 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings reveal a novel mechanism of cerebral ischemia-induced BBB damage, and implicate zinc as an effective and viable new target for reducing acute BBB damage following ischemic stroke." | 1.43 | Zinc contributes to acute cerebral ischemia-induced blood-brain barrier disruption. ( Dong, W; Ji, X; Liang, J; Liu, KJ; Luo, Y; Pan, R; Qi, Z; Shen, J; Shi, W; Yang, Y; Zhao, Y, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Y | 3 |
| Yan, F | 2 |
| Yin, J | 2 |
| Pan, R | 3 |
| Shi, W | 2 |
| Qi, Z | 3 |
| Fang, Y | 1 |
| Huang, Y | 1 |
| Li, S | 2 |
| Luo, Y | 3 |
| Ji, X | 3 |
| Liu, KJ | 3 |
| Yan, Y | 1 |
| Wang, WM | 1 |
| Liu, Z | 1 |
| Liu, AJ | 1 |
| Wang, YX | 1 |
| Wang, HG | 1 |
| An, D | 1 |
| Heng, B | 1 |
| Xie, LH | 1 |
| Duan, JL | 1 |
| Liu, YQ | 1 |
| Liang, J | 1 |
| Dong, W | 1 |
| Shen, J | 1 |
| Yang, Y | 1 |
| Bonanni, L | 1 |
| Chachar, M | 1 |
| Jover-Mengual, T | 1 |
| Li, H | 1 |
| Jones, A | 1 |
| Yokota, H | 1 |
| Ofengeim, D | 1 |
| Flannery, RJ | 1 |
| Miyawaki, T | 1 |
| Cho, CH | 1 |
| Polster, BM | 1 |
| Pypaert, M | 1 |
| Hardwick, JM | 1 |
| Sensi, SL | 1 |
| Zukin, RS | 1 |
| Jonas, EA | 1 |
5 other studies available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Cerebral Ischemia
| Article | Year |
|---|---|
Synergistic Interaction Between Zinc and Reactive Oxygen Species Amplifies Ischemic Brain Injury in Rats.
Topics: Animals; Antioxidants; Apoptosis; Biphenyl Compounds; Brain; Brain Ischemia; Chelating Agents; Ethyl | 2018 |
Chelating intracellularly accumulated zinc decreased ischemic brain injury through reducing neuronal apoptotic death.
Topics: Animals; Apoptosis; Brain Ischemia; Chelating Agents; Cytosol; Ethylenediamines; Infarction, Middle | 2014 |
The Zinc Ion Chelating Agent TPEN Attenuates Neuronal Death/apoptosis Caused by Hypoxia/ischemia Via Mediating the Pathophysiological Cascade Including Excitotoxicity, Oxidative Stress, and Inflammation.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cell Hypoxia; Chelating Agents; Disease Models, Animal; E | 2015 |
Zinc contributes to acute cerebral ischemia-induced blood-brain barrier disruption.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Ethylenediamines; Infarction, Middle Cerebral Artery; | 2016 |
Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.
Topics: Animals; Blotting, Western; Brain Ischemia; Caspases; Chelating Agents; Diagnostic Imaging; Dose-Res | 2006 |