n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Bronchial Hyperreactivity in 1 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigate the effects of a zinc chelator, N,N,N',N'-tetrakis (2-pyridyl-methyl) ethylenediamine (TPEN), on asthmatic responses in mouse models of ovalbumin (OVA)-induced airway hyperresponsiveness and allergic airway inflammation." | 3.77 | A zinc chelator TPEN attenuates airway hyperresponsiveness and airway inflammation in mice in vivo. ( Asai, Y; Fukuyama, S; Inoue, H; Matsumoto, K; Matsumoto, T; Matsunaga, Y; Moriwaki, A; Nakanishi, Y; Nakano, T; Noda, N; Zhanghui, W, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukuyama, S | 1 |
| Matsunaga, Y | 1 |
| Zhanghui, W | 1 |
| Noda, N | 1 |
| Asai, Y | 1 |
| Moriwaki, A | 1 |
| Matsumoto, T | 1 |
| Nakano, T | 1 |
| Matsumoto, K | 1 |
| Nakanishi, Y | 1 |
| Inoue, H | 1 |
1 other study available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
A zinc chelator TPEN attenuates airway hyperresponsiveness and airway inflammation in mice in vivo.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chelating Agent | 2011 |