n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Breast Neoplasms in 3 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tamoxifen-induced death was accompanied by increased oxidative stress and lysosomal membrane permeabilization (LMP) represented as release of lysosomal cathepsins into cytosol." | 5.36 | Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line. ( Cho, DH; Hwang, JJ; Kim, HN; Kim, J; Kim, MJ; Kim, Y; Kim, YS; Koh, JY; Park, SJ, 2010) |
| "Tamoxifen-induced death was accompanied by increased oxidative stress and lysosomal membrane permeabilization (LMP) represented as release of lysosomal cathepsins into cytosol." | 1.36 | Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line. ( Cho, DH; Hwang, JJ; Kim, HN; Kim, J; Kim, MJ; Kim, Y; Kim, YS; Koh, JY; Park, SJ, 2010) |
| "Treatment of breast cancer cells with different concentrations of a cell membrane permeable zinc chelator, N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) and the membrane impermeable zinc chelator, diethylenetriaminepentacetic acid, (DTPA) resulted in a significant increase of cell death." | 1.34 | Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells. ( Booy, EP; Eshraghi, M; Ghavami, S; Hashemi, M; Los, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hwang, JJ | 1 |
| Kim, HN | 1 |
| Kim, J | 1 |
| Cho, DH | 1 |
| Kim, MJ | 1 |
| Kim, YS | 1 |
| Kim, Y | 1 |
| Park, SJ | 1 |
| Koh, JY | 1 |
| Hashemi, M | 1 |
| Ghavami, S | 1 |
| Eshraghi, M | 1 |
| Booy, EP | 1 |
| Los, M | 1 |
| Kagara, N | 1 |
| Tanaka, N | 1 |
| Noguchi, S | 1 |
| Hirano, T | 1 |
3 other studies available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Breast Neoplasms
| Article | Year |
|---|---|
Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line.
Topics: Autophagy; Breast Neoplasms; Chelating Agents; Ethylenediamines; Female; Humans; Lysosomes; Oxidativ | 2010 |
Cytotoxic effects of intra and extracellular zinc chelation on human breast cancer cells.
Topics: Acetylcysteine; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell | 2007 |
Zinc and its transporter ZIP10 are involved in invasive behavior of breast cancer cells.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cation Transport Proteins; Cell Line, Tumor; Cell | 2007 |