n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine has been researched along with Asthma in 3 studies
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine: a zinc ion chelating agent; structure given in first source
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine : An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigate the effects of a zinc chelator, N,N,N',N'-tetrakis (2-pyridyl-methyl) ethylenediamine (TPEN), on asthmatic responses in mouse models of ovalbumin (OVA)-induced airway hyperresponsiveness and allergic airway inflammation." | 3.77 | A zinc chelator TPEN attenuates airway hyperresponsiveness and airway inflammation in mice in vivo. ( Asai, Y; Fukuyama, S; Inoue, H; Matsumoto, K; Matsumoto, T; Matsunaga, Y; Moriwaki, A; Nakanishi, Y; Nakano, T; Noda, N; Zhanghui, W, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sawant, SS | 1 |
| Gudipati, S | 1 |
| Veczko, SR | 1 |
| Rouge, JL | 1 |
| Fukuyama, S | 1 |
| Matsunaga, Y | 1 |
| Zhanghui, W | 1 |
| Noda, N | 1 |
| Asai, Y | 1 |
| Moriwaki, A | 1 |
| Matsumoto, T | 1 |
| Nakano, T | 1 |
| Matsumoto, K | 1 |
| Nakanishi, Y | 1 |
| Inoue, H | 1 |
| Richter, M | 1 |
| Cantin, AM | 1 |
| Beaulieu, C | 1 |
| Cloutier, A | 1 |
| Larivée, P | 1 |
3 other studies available for n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine and Asthma
| Article | Year |
|---|---|
Controlled Release of a Dual Zinc-Sensing and Gene Regulating Small Molecule from DNA Micelles.
Topics: Asthma; Chelating Agents; Delayed-Action Preparations; DNA; Ethylenediamines; Humans; Micelles; Zinc | 2023 |
A zinc chelator TPEN attenuates airway hyperresponsiveness and airway inflammation in mice in vivo.
Topics: Allergens; Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chelating Agent | 2011 |
Zinc chelators inhibit eotaxin, RANTES, and MCP-1 production in stimulated human airway epithelium and fibroblasts.
Topics: Asthma; Chelating Agents; Chemokine CCL11; Chemokine CCL2; Chemokine CCL5; Chemokines, CC; DNA-Bindi | 2003 |