Page last updated: 2024-09-03

n,n-dimethylarginine and Diabetic Nephropathies

n,n-dimethylarginine has been researched along with Diabetic Nephropathies in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (34.78)29.6817
2010's12 (52.17)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Guo, X; Jin, W; Xing, Y1
Anderson, AH; Bhat, Z; Brown, J; Brunengraber, H; Charleston, J; Chen, J; Feldman, HI; He, J; Hostetter, TH; Hsu, CY; Ix, JH; Kimmel, PL; Mehta, R; Rao, P; Sapa, H; Schelling, JR; Schrauben, SJ; Seegmiller, JC; Shafi, T; Shlipak, MG; Townsend, R; Vasan, RS; Xie, D; Zhang, X1
Bode-Böger, SM; Brilloff, S; Hohenstein, B; Hugo, C; Jarzebska, N; Martens-Lobenhoffer, J; Rexin, A; Rodionov, RN; Schneider, A; Sradnick, J; Todorov, V; Weiss, N1
Awad, AS; Cooper, TK; Gao, T; Morris, SM; Stanley, K; Wetzel, MD1
Balasubramanyam, M; Jayachandran, I; Manickam, N; Mohan, V; Paramasivam, P; Subramanian, SC; Sundararajan, S; Venkatesan, B1
Bode-Böger, SM; Brilloff, S; Heinrich, A; Hohenstein, B; Hugo, CPM; Jarzebska, N; Martens-Lobenhoffer, J; Rodionov, RN; Todorov, VT; Weiss, N1
Chen, W; He, K; Li, C; Liu, J; Ma, B; Ma, H; Tian, L; Zhao, P1
Ando, R; Fukami, K; Kaida, Y; Kaifu, K; Miyazaki, H; Nakayama, Y; Obara, N; Okuda, S; Takeuchi, M; Ueda, S; Yamagishi, S; Yokoro, M1
Agilli, M; Avci, E; Bilgi, C; Cakir, E; Cevher, SC; Yaman, H1
Bob, F; Dumitrascu, V; Gadalean, F; Gluhovschi, C; Gluhovschi, G; Jianu, DC; Petrica, L; Petrica, M; Popescu, R; Ursoniu, S; Velciov, S; Vlad, A; Vlad, D1
Jing, Z; Kuang, L; Liu, N; Yang, J1
Aycan-Ustyol, E; Bekpinar, S; Dinccag, N; Gurdol, F; Unlucerci, Y; Yenidunya, G1
Aso, Y1
Fukami, K; Hayashida, A; Kaida, Y; Kato, S; Kimoto, M; Matsumoto, Y; Matsuoka, H; Okuda, S; Shibata, R; Ueda, S; Yamagishi, S1
Babazono, T; Hanai, K; Ishii, A; Iwamoto, Y; Nyumura, I; Tanaka, M; Tanaka, N; Toya, K1
Axelsson, J; Caglar, K; Cayci, T; Eyileten, T; Kilic, S; Oguz, Y; Saglam, M; Sonmez, A; Vural, A; Yaman, H; Yenicesu, M; Yilmaz, MI1
Bartáková, V; Bělobrádková, J; Jurajda, M; Kaňková, K; Klepárník, M; Krusová, D; Kuricová, K; Malúšková, D; Mužík, J; Olšovský, J; Pácal, L; Pavlík, T; Rehořová, J; Stěpánková, S; Svojanovský, J; Tanhäuserová, V; Tomandl, J1
Fukami, K; Ishibashi, Y; Maeda, S; Matsui, T; Nishino, Y; Ojima, A; Takeuchi, M; Yamagishi, S1
Böger, RH; Maas, R; Quispe-Bravo, S; Schwedhelm, E; Skamira, C1
Bellinghieri, G; De Luca, G; Di Giorgio, RM; Mallamace, A; Santoro, D; Savica, V1
Chang, JW; Chun, S; Kim, SB; Kim, TH; Lee, EK; Lee, KU; Min, WK; Park, JS1
Böger, RH; Galle, J; Pinnetti, S; Schwedhelm, E; Wanner, C1
Beck, W; Deppisch, RM; Pommer, W; Riedel, E; Schröder, M1

Reviews

4 review(s) available for n,n-dimethylarginine and Diabetic Nephropathies

ArticleYear
Role of ADMA in the pathogenesis of microvascular complications in type 2 diabetes mellitus.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Humans

2023
Relationship between Serum Asymmetric Dimethylarginine Level and Microvascular Complications in Diabetes Mellitus: A Meta-Analysis.
    BioMed research international, 2019, Volume: 2019

    Topics: Arginine; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Female; Humans; Male; Risk Factors

2019
Cardiovascular disease in patients with diabetic nephropathy.
    Current molecular medicine, 2008, Volume: 8, Issue:6

    Topics: Anemia; Arginine; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Enzyme Inhibitors; Glycation End Products, Advanced; Homocysteine; Humans; Prognosis; Risk Factors

2008
L-arginine: a new opportunity in the management of clinical derangements in dialysis patients.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2006, Volume: 16, Issue:3

    Topics: Adult; Aged; Animals; Arginine; Citrulline; Diabetic Nephropathies; Endothelium, Vascular; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Renal Dialysis

2006

Trials

2 trial(s) available for n,n-dimethylarginine and Diabetic Nephropathies

ArticleYear
Effects of alpha-lipoic acid on the plasma levels of asymmetric dimethylarginine in diabetic end-stage renal disease patients on hemodialysis: a pilot study.
    American journal of nephrology, 2007, Volume: 27, Issue:1

    Topics: Adult; Antioxidants; Arginine; Biomarkers; C-Reactive Protein; Cholesterol; Chromatography, High Pressure Liquid; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Kidney Failure, Chronic; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide Synthase; Oxidation-Reduction; Pilot Projects; Renal Dialysis; Thioctic Acid; Treatment Outcome

2007
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:10

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Proteinuria; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan

2008

Other Studies

17 other study(ies) available for n,n-dimethylarginine and Diabetic Nephropathies

ArticleYear
Association of urine and plasma ADMA with atherosclerotic risk in DKD cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023, Nov-30, Volume: 38, Issue:12

    Topics: Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus; Diabetic Nephropathies; Heart Failure; Humans; Renal Insufficiency, Chronic

2023
ADMA elevation does not exacerbate development of diabetic nephropathy in mice with streptozotocin-induced diabetes mellitus.
    Atherosclerosis. Supplements, 2019, Volume: 40

    Topics: Amidohydrolases; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Filtration Rate; Male; Mice; Mice, Inbred C57BL; Risk Factors; Streptozocin

2019
Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy.
    American journal of physiology. Renal physiology, 2020, 02-01, Volume: 318, Issue:2

    Topics: Adenoviridae; Albuminuria; Amidohydrolases; Animals; Arginine; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Genetic Therapy; Genetic Vectors; Inflammation Mediators; Kidney; Male; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Thiobarbituric Acid Reactive Substances

2020
Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury.
    Clinical biochemistry, 2017, Volume: 50, Issue:15

    Topics: Adult; Albuminuria; Animals; Arginine; Asian People; Biomarkers; Cell Line; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fibroblasts; Glomerular Mesangium; Glycated Hemoglobin; Humans; India; Male; Middle Aged; Rats

2017
ADMA reduction does not protect mice with streptozotocin-induced diabetes mellitus from development of diabetic nephropathy.
    Atherosclerosis. Supplements, 2017, Volume: 30

    Topics: Albuminuria; Amidohydrolases; Animals; Arginine; Cell Proliferation; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Down-Regulation; Genetic Predisposition to Disease; Glomerular Mesangium; Glomerulonephritis; Hydrolysis; Kidney; Male; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Streptozocin

2017
Involvement of advanced glycation end product-induced asymmetric dimethylarginine generation in endothelial dysfunction.
    Diabetes & vascular disease research, 2013, Volume: 10, Issue:5

    Topics: Aged; Amidohydrolases; Arginine; Atherosclerosis; Cells, Cultured; Diabetic Nephropathies; Endothelial Cells; Female; Glycation End Products, Advanced; Humans; Male; Middle Aged; Nitric Oxide; Reactive Oxygen Species; Vascular Diseases

2013
Determination of oxidative stress and cellular inflammation in patients with diabetic nephropathy and non-diabetic nephropathy being administered hemodialysis treatment due to chronic renal failure.
    Renal failure, 2014, Volume: 36, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Arginine; Biomarkers; C-Reactive Protein; Case-Control Studies; Deoxyguanosine; Diabetic Nephropathies; Female; Humans; Inflammation; Interleukin-6; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Neopterin; Oxidative Stress; Tumor Necrosis Factor-alpha

2014
Glycated peptides are associated with the variability of endothelial dysfunction in the cerebral vessels and the kidney in type 2 diabetes mellitus patients: a cross-sectional study.
    Journal of diabetes and its complications, 2015, Volume: 29, Issue:2

    Topics: Aged; Albuminuria; Arginine; Biomarkers; Breath Holding; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Endothelium, Vascular; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Male; Middle Aged; Outpatient Clinics, Hospital; Romania; Severity of Illness Index; Vasculitis, Central Nervous System

2015
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics.
    Bioanalysis, 2015, Volume: 7, Issue:10

    Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry

2015
The effect of nephropathy on plasma sphingosine 1-phosphate concentrations in patients with type 2 diabetes.
    Clinical biochemistry, 2015, Volume: 48, Issue:18

    Topics: Albuminuria; Apolipoproteins; Apolipoproteins M; Arginine; Biological Transport; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Lipocalins; Lysophospholipids; Male; Middle Aged; Sphingosine; Triglycerides

2015
Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:4

    Topics: Adenoviridae; Amidohydrolases; Animals; Arginine; Diabetic Nephropathies; Disease Models, Animal; Genetic Vectors; Ischemia; Kidney; Male; Nephritis, Interstitial; Nitric Oxide; Rats; Rats, Sprague-Dawley

2009
Asymmetric dimethylarginine is closely associated with the development and progression of nephropathy in patients with type 2 diabetes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: Adult; Aged; Albuminuria; Arginine; Biomarkers; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Japan; Male; Middle Aged; Nitric Oxide Synthase; Prognosis; Proportional Hazards Models; Prospective Studies

2009
Reduced proteinuria using ramipril in diabetic CKD stage 1 decreases circulating cell death receptor activators concurrently with ADMA. A novel pathophysiological pathway?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:10

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Chronic Disease; Diabetic Nephropathies; fas Receptor; Female; Humans; Kidney Diseases; Male; Middle Aged; Multivariate Analysis; Myostatin; Proteinuria; Ramipril

2010
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
    Kidney & blood pressure research, 2012, Volume: 36, Issue:1

    Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors

2012
Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression.
    The American journal of pathology, 2013, Volume: 182, Issue:1

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; Exenatide; Gene Expression Regulation, Enzymologic; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glycation End Products, Advanced; Humans; Hypertrophy; Hypoglycemic Agents; Kidney; Kidney Glomerulus; Kidney Tubules; Macrophages; Male; Peptides; Protein-Arginine N-Methyltransferases; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Glucagon; Receptors, Immunologic; Repressor Proteins; RNA, Messenger; Venoms

2013
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Benzimidazoles; Benzoates; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Endothelium, Vascular; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency; Telmisartan; Tetrazoles; Valine; Valsartan

2005
Increased reduction of dimethylarginines and lowered interdialytic blood pressure by the use of biocompatible membranes.
    Kidney international. Supplement, 2001, Volume: 78

    Topics: Adult; Aged; Arginine; beta 2-Microglobulin; Biocompatible Materials; Blood Pressure; Diabetic Nephropathies; Female; Hematocrit; Hemodiafiltration; Hemoglobins; Humans; Kidney Failure, Chronic; Kidneys, Artificial; Male; Membranes, Artificial; Middle Aged; Renal Dialysis; Urea

2001