Page last updated: 2024-09-03

n,n-dimethylarginine and Diabetes Mellitus, Adult-Onset

n,n-dimethylarginine has been researched along with Diabetes Mellitus, Adult-Onset in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's24 (26.09)29.6817
2010's58 (63.04)24.3611
2020's10 (10.87)2.80

Authors

AuthorsStudies
Bosch, A; Fromm, MF; Gemeinhardt, A; Gessner, A; Kannenkeril, D; Maas, R; Mayr, A; Schmieder, RE; Staerk, C1
Fang, WJ; Li, XM; Xiong, Y; Zhou, XK1
Deng, Z; Hu, C; Jia, W; Wang, S; Yan, D; Zhang, H; Zhang, R; Zheng, X1
Guo, X; Jin, W; Xing, Y1
Abdel-Rahman, AA; Leffler, KE1
Derkacz, A; Gać, P; Gocławska, K; Jurdziak, M; Mazur, G; Poręba, M; Poręba, R; Szuba, A; Trzmielewska, E1
Kulwas, A; Rość, D; Wieczór, AM; Wieczór, R1
Doroszko, A; Fortuna, P; Gajecki, D; Gawryś, J; Gawryś, K; Leśniewska, J; Majda, F; Mlynarz, P; Szahidewicz-Krupska, E; Wiśniewski, J1
Adamiec, R; Dumas, I; Fiodorenko-Dumas, Z; Małecki, R; Paprocka-Borowicz, M; Rabczynski, M1
Doroszko, A; Fortuna, P; Gajecki, D; Gawryś, J; Szahidewicz-Krupska, E; Wiśniewski, J1
Berge, RK; Gaardbo, JC; Gerstoft, J; Hove-Skovsgaard, M; Kolte, L; Nielsen, SD; Seljeflot, I; Svardal, A; Trøseid, M; Ullum, H; Winding, K1
Balasubramanyam, M; Jayachandran, I; Manickam, N; Mohan, V; Paramasivam, P; Subramanian, SC; Sundararajan, S; Venkatesan, B1
Adamiec, R; Dumas, I; Fiodorenko-Dumas, Z; Mastej, K1
Batista, M; Mayer, S; Quinto, M; Triches, CB; Zanella, MT1
Batista, MC; Mayer, S; Quinto, BMR; Triches, CB; Zanella, MT1
Aukrust, P; Gaardbo, JC; Gelpi, M; Gerstoft, J; Hoel, H; Holm, K; Hov, JR; Hove-Skovsgaard, M; Kummen, M; Nielsen, SD; Nwosu, F; Rudi, K; Seljeflot, I; Trøseid, M; Ueland, PM; Ullum, H; Valeur, J1
Abdollahi, M; Effatpanah, M; Hashemi, R; Khorshidi, M; Kord Varkane, H; Makhdoomi Arzati, M; Mohammadzadeh Honarvar, N; Saedisomeolia, A; Yekaninejad, MS; Zarezadeh, M1
Arós, F; Bullo, M; Clish, C; Cofán, M; Corella, D; Dennis, C; Estruch, R; Fitó, M; Guasch-Ferré, M; Gutiérrez-Bedmar, M; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Papandreou, C; Razquin, C; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Sorlí, JV; Toledo, E; Wang, DD; Yu, E1
Fukuo, K; Ikeda, H; Minami, M; Okada, S; Otaki, N; Yano, M; Yokoro, M1
Bekki, M; Fukumoto, Y; Honda, A; Igata, S; Kojima, R; Maeda, S; Matsui, T; Nakamura, T; Sugiyama, Y; Sun, J; Tahara, A; Tahara, N; Yamagishi, SI; Yoshida, R1
Artusi, C; Cecchet, D; Millioni, R; Plebani, M; Puricelli, L; Tessari, P; Vedovato, M; Vettore, M1
Arıbaş, A; Ayhan, SS; Erdem, SS; Kayrak, M; Taner, A; Tekinalp, M; Unlu, A1
Dubiel, JS; Jaźwińska-Kozuba, A; Kruszelnicka, O; Rakowski, T; Surdacki, A1
Imaizumi, T; Mizoguchi, M; Tahara, A; Tahara, N; Yamagishi, S1
Bøtker, HE; Møller, N1
Ajjan, R; Anderssohn, M; Böger, RH; Grant, PJ; Lüneburg, N; McLachlan, S; Price, JF; Robertson, C; Schwedhelm, E; Strachan, MW; Williamson, RM1
Avdagić, N; Hasić, S; Huskić, J; Jadrić, R; Mulabegović, N; Valjevac, A; Začiragić, A1
Abdul-Ghani, M; Cakirca, M; Camli, AA; Cikrikcioglu, MA; Erkoc, R; Hursitoglu, M; Kanat, M; Karatoprak, C; Kiskac, M; Soysal, P; Zorlu, M1
Akalin, A; Arabul, M; Celik, M; Cerrah, S1
Fang, WJ; He, ZM; Leng, YP; Qiu, N; Xiong, Y; Zhang, M1
Aukrust, P; Consoli, A; Davì, G; Di Fulvio, P; Formoso, G; Lattanzio, S; Liani, R; Santilli, F; Ueland, T; Vazzana, N1
Bob, F; Dumitrascu, V; Gadalean, F; Gluhovschi, C; Gluhovschi, G; Jianu, DC; Petrica, L; Petrica, M; Popescu, R; Ursoniu, S; Velciov, S; Vlad, A; Vlad, D1
Das, UN1
Bai, YP; Gong, ZC; Hu, CP; Jiang, JL; Li, YJ; Liu, SY; Yuan, Q1
Chyrchel, B; Golay, A; Kruszelnicka, O; Surdacki, A1
Kaneko, K; Kuroyanagi, Y; Takaya, J; Tanabe, Y1
Akilli, H; Alibasic, H; Aribas, A; Gunduz, M; Kayrak, M; Taner, A; Tekinalp, M; Unlu, A; Yildirim, S1
Jing, Z; Kuang, L; Liu, N; Yang, J1
Ebadi, M; Eshraghian, M; Esteghamati, A; Hosseinzadeh-Attar, M; Khorrami, E; Kolahdouz Mohammadi, R; Nakhjavani, M1
Aycan-Ustyol, E; Bekpinar, S; Dinccag, N; Gurdol, F; Unlucerci, Y; Yenidunya, G1
He, J; Jing, Z; Kuang, L; Liu, N; Sun, Z; Wang, Y; Yang, J1
Boaz, M; Ganz, T; Gilad, S; Limor, R; Stern, N; Wainstein, J1
Khan, MA; Tariq, K1
Bode-Böger, SM; Bornstein, SR; Brilloff, S; Brocker, C; Burdin, DV; Demyanov, AV; Gonzalez, F; Jarzebska, N; Kolobov, AA; Maas, R; Martens-Lobenhoffer, J; Mieth, M; Rodionov, RN; Samusik, N; Soshnev, AA; Weiss, N1
Betou, K; Fujiwara, R; Ida, S; Imataka, K; Ishihara, Y; Kaneko, R; Kobayashi, C; Monguchi, K; Murata, K; Takahashi, H; Uchida, A1
Bode-Böger, SM; Ertl, T; Lakatos, O; Martens-Lobenhoffer, J; Sulyok, E; Vida, G1
Babazono, T; Hanai, K; Ishii, A; Iwamoto, Y; Nyumura, I; Tanaka, M; Tanaka, N; Toya, K1
Carlioglu, A; Ilhan, A; Karakurt, F; Kasapoglu, B; Kaya, A; Koktener, A; Ozbek, M; Uyar, ME1
Flacke, F; Forst, S; Forst, T; Hohberg, C; Krasner, A; Pfützner, A; Pichotta, P; Steiner, S; Tarakci, E1
Francesconi, M; Mittermayer, F; Pleiner, J; Wolzt, M1
Averna, M; Ciabattoni, G; Consoli, A; Davì, G; Di Fulvio, P; Formoso, G; Ganci, A; Lattanzio, S; Lauro, R; Miccoli, R; Patrono, C; Pulizzi, N; Santilli, F; Sbraccia, P1
Brasacchio, D; Chin-Dusting, J; Cooper, ME; Coughlan, MT; Forbes, JM; Harris, E; Kaye, D; Paavonen, K; Soro-Paavonen, A; Thomas, MC; Tong, DC; Venardos, K; Zhang, WZ1
Abhary, S; Burdon, KP; Craig, JE; Javadiyan, S; Kasmeridis, N; Kuot, A; Petrovsky, N; Whiting, MJ1
Asgarani, F; Esteghamati, A; Ghadiri-Anari, A; Karimi-Jafari, H; Khalilzadeh, O; Nakhjavani, M1
Kanazawa, I; Nabika, T; Notsu, Y; Sugimoto, T; Yamaguchi, T; Yano, S2
Aydogdu, A; Celebi, G; Dogru, T; Erdem, G; Genc, H; Haymana, C; Kurt, I; Kutlu, M; Ozturk, O; Safer, U; Sonmez, A; Tapan, S; Tasci, I; Taslipinar, A; Yilmaz, MI1
Bluck, L; Corander, M; Siervo, M; Stranges, S1
Dain, A; Das, UN; Eynard, AR; Repossi, G1
Chung, MY; Hsu, CP; Lin, MW; Lin, SJ; Lu, TM1
Everett, CJ; King, DE; Player, M1
Chen, B; Ji, X; Liang, Y; Wang, Y; Yi, L; Zhang, P; Zhou, Z1
El-Mesallamy, HO; Ezzat, OA; Hamdy, NM; Reda, AM1
Anburajan, M; Bidyarasmi, S; Menaka, M; Raj, B; Sivanandam, S; Venkatraman, B1
Anders, S; Forst, T; Michelson, G; Mitry, M; Pfützner, A; Ratter, F; Weber, MM; Wilhelm, B1
Asgarani, F; Bathaie, SZ; Esteghamati, A; Ghazizadeh, Z; Khalilzadeh, O; Morteza, A; Nakhjavani, M1
Akyel, A; Arslan, M; Boyaci, B; Çengel, A; Elbeğ, Ş; Şahinarslan, A; Tavil, Y; Topal, S; Yayla, Ç1
Boemi, M; Bonfigli, AR; Ceriello, A; Cucchi, M; Franceschi, C; Marchegiani, F; Marra, M; Sirolla, C; Spazzafumo, L; Testa, I; Testa, R1
Chi, Y; Shao, Y; Wang, X; Wang, Y; Xia, W1
Bartáková, V; Bělobrádková, J; Jurajda, M; Kaňková, K; Klepárník, M; Krusová, D; Kuricová, K; Malúšková, D; Mužík, J; Olšovský, J; Pácal, L; Pavlík, T; Rehořová, J; Stěpánková, S; Svojanovský, J; Tanhäuserová, V; Tomandl, J1
Grillo, N; Perticone, F; Quero, M; Sciacqua, A; Sesti, G1
Egashira, K; Ito, A; Muramatsu, K; Narishige, T; Takeshita, A1
Laakso, J; Laaksonen, R; Lehtimäki, T; Päivä, H; Pasternack, A; Rantalaiho, V; Ruokonen, I; Wirta, O1
Böger, RH1
Fu, S; Fu, Y; Lei, M; Xiong, Y1
Daimon, M; Hasegawa, R; Himi, T; Kawata, T; Komuro, I; Sekine, T; Teramoto, K; Toyoda, T; Uchida, D; Yamamoto, K; Yoshida, K2
Hofer, M; Krugluger, W; Krzyzanowska, K; Mittermayer, F; Schernthaner, G; Schnack, C; Wolzt, M1
Böger, RH; Maas, R; Quispe-Bravo, S; Schwedhelm, E; Skamira, C1
Goto, Y; Harano, Y; Kanda, M; Miyazaki, S; Nonogi, H; Suzuki, M; Yasuda, S1
Brouwer, CB; Rauwerda, JA; Smulders, YM; Spoelstra-de Man, AM; Stehouwer, CD; Teerlink, T1
Auteri, A; Blardi, P; Ceccatelli, L; De Franco, V; de Lalla, A; Meini, S; Pieragalli, D1
Ding, H; Triggle, CR1
Gao, HW; Hong, TP; Lin, YJ; Wang, HN; Xie, C1
Krzyzanowska, K; Mittermayer, F; Schernthaner, G; Wolzt, M1
Baylis, C; Boykin, JV1
Bucciarelli, L; Ciabattoni, G; Clissa, C; Consoli, A; Davì, G; Devangelio, E; Ferroni, P; Formoso, G; Michetti, N; Santilli, F1
Kautzky-Willer, A; Langenberger, H; Mittermayer, F; Pacini, G; Pleiner, J; Schaller, G; Tura, A; Winzer, C; Wolzt, M1
Böger, RH; Galle, J; Pinnetti, S; Schwedhelm, E; Wanner, C1
Berglund, L; Bryant, TA; Cannon, PJ; Chen, NT; Di Tullio, MR; Donis, JA; Fard, A; Ginsberg, HN; Homma, S; Ramasamy, R; Sciacca, R; Torres-Tamayo, M; Tuck, CH; Wu, HD1
Abbasi, F; Asagmi, T; Cooke, JP; Lamendola, C; McLaughlin, T; Reaven, GM; Stuehlinger, M; Tsao, PS1
Abbasi, F; Asagami, T; Cooke, JP; Lamendola, C; McLaughlin, T; Reaven, GM; Stuelinger, M; Tsao, PS1

Reviews

6 review(s) available for n,n-dimethylarginine and Diabetes Mellitus, Adult-Onset

ArticleYear
Role of ADMA in the pathogenesis of microvascular complications in type 2 diabetes mellitus.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Humans

2023
Nutritional factors in the prevention and management of coronary artery disease and heart failure.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:2

    Topics: Alprostadil; Anti-Inflammatory Agents; Arginine; CD59 Antigens; Coronary Artery Disease; Diabetes Mellitus, Type 2; Epoprostenol; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Folic Acid; Heart Failure; Humans; Hypertension; Lipoxins; Magnesium; Male; Middle Aged; Nitric Oxide; Nutritional Status; Serum Albumin; Vasodilation; Vitamin B 12; Vitamin B 6

2015
Post-challenge hyperglycaemia, nitric oxide production and endothelial dysfunction: the putative role of asymmetric dimethylarginine (ADMA).
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2011, Volume: 21, Issue:1

    Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Glucose; Glucose Tolerance Test; Heart Diseases; Humans; Hyperglycemia; Metabolic Diseases; Nitric Oxide; Oxidative Stress

2011
L-arginine, NO and asymmetrical dimethylarginine in hypertension and type 2 diabetes.
    Frontiers in bioscience (Landmark edition), 2011, 01-01, Volume: 16, Issue:1

    Topics: Animals; Antihypertensive Agents; Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Hypertension; Insulin Resistance; Nitric Oxide; Nitric Oxide Synthase Type III; Prognosis

2011
[Asymmetrical methylarginine (ADMA) as a cardiovascular risk factor: epidemiological and prospective data].
    Deutsche medizinische Wochenschrift (1946), 2004, Apr-08, Volume: 129, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cells, Cultured; Child; Coronary Disease; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Free Radicals; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Nitric Oxide Synthase; Oxidative Stress; Pre-Eclampsia; Pregnancy; Prospective Studies; Rabbits; Regression Analysis; Renal Dialysis; Risk Factors; Stroke

2004
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium.
    Vascular health and risk management, 2005, Volume: 1, Issue:1

    Topics: Arginine; Biological Factors; Biomarkers; C-Reactive Protein; Cell Differentiation; Cell Proliferation; Cellular Senescence; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelial Cells; Endothelium, Vascular; Humans; Hyperglycemia; Nitric Oxide; Oxidative Stress; Stem Cells; Vasodilation; Vasodilator Agents

2005

Trials

20 trial(s) available for n,n-dimethylarginine and Diabetes Mellitus, Adult-Onset

ArticleYear
Effects of treatment with SGLT-2 inhibitors on arginine-related cardiovascular and renal biomarkers.
    Cardiovascular diabetology, 2022, 01-06, Volume: 21, Issue:1

    Topics: Arginine; Benzhydryl Compounds; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome

2022
Asymmetric dimethylarginine and soluble inter-cellular adhesion molecule-1 serum levels alteration following ginger supplementation in patients with type 2 diabetes: a randomized double-blind, placebo-controlled clinical trial.
    Journal of complementary & integrative medicine, 2018, Aug-11, Volume: 16, Issue:2

    Topics: Adult; Arginine; Biomarkers; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Plant Extracts; Zingiber officinale

2018
Serum Levels of Protein-Bound Methylglyoxal-Derived Hydroimidazolone-1 are Independently Correlated with Asymmetric Dimethylarginine.
    Rejuvenation research, 2019, Volume: 22, Issue:5

    Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Imidazoles; Inflammation; Male; Middle Aged; Protein Binding; Pyruvaldehyde; Vascular Stiffness

2019
Pioglitazone decreases asymmetric dimethylarginine levels in patients with impaired glucose tolerance or type 2 diabetes.
    Rejuvenation research, 2013, Volume: 16, Issue:5

    Topics: Aged; Aged, 80 and over; Arginine; Diabetes Mellitus, Type 2; Female; Fibronectins; Glucose Intolerance; Humans; Male; Middle Aged; Pioglitazone; Regression Analysis; Sulfonylurea Compounds; Thiazolidinediones

2013
Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients.
    Drug design, development and therapy, 2014, Volume: 8

    Topics: Adamantane; Adult; Aged; Arginine; C-Reactive Protein; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Female; Fibrinogen; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Nitriles; Pyrrolidines; Vildagliptin

2014
Differential associations of circulating asymmetric dimethylarginine and cell adhesion molecules with metformin use in patients with type 2 diabetes mellitus and stable coronary artery disease.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Aged; Aged, 80 and over; Arginine; Cell Adhesion Molecules; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Metformin; Middle Aged; Time Factors

2015
Reduction in asymmetric dimethylarginine plasma levels by coenzyme Q10 supplementation in patients with type 2 diabetes mellitus.
    Minerva endocrinologica, 2015, Volume: 40, Issue:4

    Topics: Adult; Aged; Antioxidants; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Ubiquinone

2015
Effect of trelagliptin on vascular endothelial functions and serum adiponectin level in patients with type 2 diabetes: a preliminary single-arm prospective pilot study.
    Cardiovascular diabetology, 2016, 11-04, Volume: 15, Issue:1

    Topics: Adiponectin; Adult; Aged; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Japan; Male; Middle Aged; Pilot Projects; Prospective Studies; Time Factors; Treatment Outcome; Up-Regulation; Uracil; Vasodilation

2016
Postprandial vascular effects of VIAject compared with insulin lispro and regular human insulin in patients with type 2 diabetes.
    Diabetes care, 2010, Volume: 33, Issue:1

    Topics: Arginine; Blood Glucose; Blood Vessels; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Lispro; Male; Microcirculation; Middle Aged; Postprandial Period; Tyrosine

2010
Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus.
    Translational research : the journal of laboratory and clinical medicine, 2010, Volume: 155, Issue:1

    Topics: Arginine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Male; Middle Aged; Thioctic Acid

2010
Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:4

    Topics: Acarbose; Aged; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; CD40 Ligand; Diabetes Mellitus, Type 2; Dinoprost; Double-Blind Method; Enzyme Inhibitors; Female; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Italy; Lipid Peroxidation; Male; Middle Aged; P-Selectin; Platelet Activation; Postprandial Period; Thromboxane B2; Time Factors; Treatment Outcome

2010
The impact of pioglitazone on ADMA and oxidative stress markers in patients with type 2 diabetes.
    Primary care diabetes, 2012, Volume: 6, Issue:2

    Topics: Academic Medical Centers; Arginine; Biomarkers; Cross-Over Studies; Diabetes Mellitus, Type 2; Dinoprost; F2-Isoprostanes; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Pioglitazone; Prospective Studies; South Carolina; Thiazolidinediones; Time Factors; Treatment Outcome

2012
Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function.
    Diabetic medicine : a journal of the British Diabetic Association, 2012, Volume: 29, Issue:9

    Topics: Adult; Aged; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; E-Selectin; Endothelium, Vascular; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Liraglutide; Male; Metformin; Microcirculation; Middle Aged; Plasminogen Activator Inhibitor 1; Proinsulin; Prospective Studies

2012
No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk.
    Clinical endocrinology, 2006, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Pyridoxine; Risk Factors; Time Factors; Treatment Failure; Vitamin B Complex

2006
Effect of iloprost on plasma asymmetric dimethylarginine and plasma and platelet serotonin in patients with peripheral arterial occlusive disease.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:3-4

    Topics: Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Blood Platelets; Blood Pressure; Diabetes Mellitus, Type 2; Drug Administration Schedule; Exercise Test; Female; Humans; Iloprost; Infusions, Intravenous; Male; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Serotonin; Treatment Outcome

2006
Beneficial metabolic effects of nateglinide versus acarbose in patients with newly-diagnosed type 2 diabetes.
    Acta pharmacologica Sinica, 2007, Volume: 28, Issue:4

    Topics: Acarbose; Arginine; Blood Glucose; Cross-Over Studies; Cyclohexanes; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Lipids; Male; Middle Aged; Nateglinide; Phenylalanine; Prospective Studies

2007
Hyperbaric oxygen therapy mediates increased nitric oxide production associated with wound healing: a preliminary study.
    Advances in skin & wound care, 2007, Volume: 20, Issue:7

    Topics: Arginine; Chromatography, High Pressure Liquid; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exudates and Transudates; Fasting; Female; Granulation Tissue; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Nitric Oxide; Oxidation-Reduction; Time Factors; Treatment Outcome; Wound Healing; Wounds and Injuries

2007
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:10

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Proteinuria; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan

2008
Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes.
    Arteriosclerosis, thrombosis, and vascular biology, 2000, Volume: 20, Issue:9

    Topics: Adult; Aged; Arginine; Diabetes Mellitus, Type 2; Dietary Fats; Endothelium, Vascular; Female; Humans; Lipids; Male; Middle Aged; Triglycerides; Vasodilation

2000
Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes.
    Metabolism: clinical and experimental, 2002, Volume: 51, Issue:7

    Topics: Arginine; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Treatment Outcome

2002

Other Studies

66 other study(ies) available for n,n-dimethylarginine and Diabetes Mellitus, Adult-Onset

ArticleYear
Resveratrol improves diabetic cardiomyopathy by preventing asymmetric dimethylarginine-caused peroxisome proliferator-activated receptor-γ coactivator-1α acetylation.
    European journal of pharmacology, 2022, Dec-05, Volume: 936

    Topics: Acetylation; Animals; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Myocytes, Cardiac; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Rats; Resveratrol; Sirtuin 1

2022
The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy.
    Cardiovascular diabetology, 2022, 12-02, Volume: 21, Issue:1

    Topics: Amidohydrolases; Diabetes Complications; Diabetes Mellitus, Type 2; Genotype; Haptoglobins; Humans; Vascular Diseases

2022
Restoration of Adiponectin-Connexin43 Signaling Mitigates Myocardial Inflammation and Dysfunction in Diabetic Female Rats.
    Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:3

    Topics: Adiponectin; Animals; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Estradiol; Estrogen Receptor alpha; Female; Heme Oxygenase (Decyclizing); Hypertrophy, Left Ventricular; Ovariectomy; Piperidines; Rats, Wistar; Receptors, Adiponectin; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2020
Cardiovascular risk factors and the concentration of asymmetric dimethylarginine.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2020, Volume: 29, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Middle Aged; Risk Factors

2020
ADMA (asymmetric dimethylarginine) and angiogenic potential in patients with type 2 diabetes and prediabetes.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:2

    Topics: Adult; Aged; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Neovascularization, Physiologic; Prediabetic State; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2021
Increased Intraplatelet ADMA Level May Promote Platelet Activation in Diabetes Mellitus.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Adenosine Diphosphate; Adult; Aged; Arginine; Blood Platelets; Calcium; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Platelet Activation; Platelet Aggregation; Risk Factors

2020
Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
    Acta biochimica Polonica, 2021, Feb-05, Volume: 68, Issue:1

    Topics: Adult; Aged; Arginine; Atherosclerosis; Carotid Artery, Internal; Carotid Intima-Media Thickness; Case-Control Studies; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Middle Aged; Risk Factors; Ultrasonography, Doppler, Color

2021
A Cross-Talk between the Erythrocyte L-Arginine/ADMA/Nitric Oxide Metabolic Pathway and the Endothelial Function in Subjects with Type 2 Diabetes Mellitus.
    Nutrients, 2021, Jul-04, Volume: 13, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Erythrocytes; Female; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Nitric Oxide

2021
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation.
    BMC infectious diseases, 2017, 03-29, Volume: 17, Issue:1

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; HIV Infections; Humans; Inflammation; Male; Methylamines; Middle Aged; Risk Factors; Tandem Mass Spectrometry

2017
Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury.
    Clinical biochemistry, 2017, Volume: 50, Issue:15

    Topics: Adult; Albuminuria; Animals; Arginine; Asian People; Biomarkers; Cell Line; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fibroblasts; Glomerular Mesangium; Glycated Hemoglobin; Humans; India; Male; Middle Aged; Rats

2017
Physical activity - related changes in ADMA and vWF levels in patients with type 2 diabetes: A preliminary study.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2017, Volume: 26, Issue:4

    Topics: Adult; Arginine; Cholesterol, HDL; Diabetes Mellitus, Type 2; Exercise; Female; Humans; Male; Middle Aged; von Willebrand Factor

2017
Relation of asymmetrical dimethylarginine levels with renal outcomes in hypertensive patients with and without type 2 diabetes mellitus.
    Journal of diabetes and its complications, 2018, Volume: 32, Issue:3

    Topics: Aged; Albuminuria; Arginine; Biomarkers; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic

2018
Association of endothelial dysfunction with cardiovascular risk factors and new-onset diabetes mellitus in patients with hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:5

    Topics: Aged; Arginine; Brazil; C-Reactive Protein; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Nitric Oxide Synthase; Predictive Value of Tests; Prospective Studies; Risk Factors; Triglycerides

2018
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction.
    Scientific reports, 2018, 04-30, Volume: 8, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelium; Feces; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Inflammation; Kynurenine; Male; Metabolism; Middle Aged; Neopterin; Risk Factors; RNA, Ribosomal, 16S; Tryptophan

2018
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
    Diabetes, obesity & metabolism, 2019, Volume: 21, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors

2019
Urinary sodium-to-potassium ratio and serum asymmetric dimethylarginine levels in patients with type 2 diabetes.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2018, Volume: 41, Issue:11

    Topics: Adult; Aged, 80 and over; Arginine; Blood Pressure; Carotid Intima-Media Thickness; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Obesity; Potassium; Sodium

2018
Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo.
    Diabetes, 2013, Volume: 62, Issue:8

    Topics: Adult; Age Factors; Aged; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Humans; Hypercholesterolemia; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged; Nitric Oxide

2013
The value of serum asymmetric dimethylarginine levels for the determination of masked hypertension in patients with diabetes mellitus.
    Atherosclerosis, 2013, Volume: 228, Issue:2

    Topics: Adult; Arginine; Biomarkers; Blood Pressure Monitoring, Ambulatory; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Fluorescence; Humans; Hypertension; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Predictive Value of Tests; Prevalence; Risk Factors; Turkey

2013
Asymmetric dimethylarginine predicts decline of glucose tolerance in men with stable coronary artery disease: a 4.5-year follow-up study.
    Cardiovascular diabetology, 2013, Volume: 12

    Topics: Adult; Aged; Angina, Stable; Arginine; Diabetes Mellitus, Type 2; Follow-Up Studies; Glucose Intolerance; Glucose Tolerance Test; Humans; Male; Middle Aged; Prediabetic State; Prognosis; Proportional Hazards Models; Risk Factors

2013
ON NO--the continuing story of nitric oxide, diabetes, and cardiovascular disease.
    Diabetes, 2013, Volume: 62, Issue:8

    Topics: Arginine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Male; Nitric Oxide

2013
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Environment; Female; Genotype; Humans; Intermittent Claudication; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors

2014
An assessment of correlation between serum asymmetric dimethylarginine and glycated haemoglobin in patients with type 2 diabetes mellitus.
    Bosnian journal of basic medical sciences, 2014, Volume: 14, Issue:1

    Topics: Arginine; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Male; Middle Aged; Nephelometry and Turbidimetry; Oxidative Stress

2014
Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients.
    Journal of diabetes research, 2014, Volume: 2014

    Topics: Aged; Arginine; Atherosclerosis; Biomarkers; Blood Sedimentation; C-Reactive Protein; Carotid Intima-Media Thickness; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Fibrinogen; Homocysteine; Humans; Inflammation Mediators; Male; Middle Aged; Regression Analysis; Systemic Vasculitis; Up-Regulation

2014
Involvement of increased endogenous asymmetric dimethylarginine in the hepatic endoplasmic reticulum stress of type 2 diabetic rats.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Arginine; Cell Line, Tumor; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Liver; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction

2014
Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin.
    Journal of the American Heart Association, 2014, Jul-18, Volume: 3, Issue:4

    Topics: Aged; Arginine; Aspirin; Biomarkers; Cardiovascular Diseases; Case-Control Studies; CD40 Ligand; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxane B2; Wnt Signaling Pathway

2014
Glycated peptides are associated with the variability of endothelial dysfunction in the cerebral vessels and the kidney in type 2 diabetes mellitus patients: a cross-sectional study.
    Journal of diabetes and its complications, 2015, Volume: 29, Issue:2

    Topics: Aged; Albuminuria; Arginine; Biomarkers; Breath Holding; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Endothelium, Vascular; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Male; Middle Aged; Outpatient Clinics, Hospital; Romania; Severity of Illness Index; Vasculitis, Central Nervous System

2015
Accelerated onset of senescence of endothelial progenitor cells in patients with type 2 diabetes mellitus: role of dimethylarginine dimethylaminohydrolase 2 and asymmetric dimethylarginine.
    Biochemical and biophysical research communications, 2015, Mar-20, Volume: 458, Issue:4

    Topics: Amidohydrolases; Arginine; Cellular Senescence; Diabetes Mellitus, Type 2; Endothelial Progenitor Cells; Female; Humans; Male; Middle Aged; Sirtuin 1

2015
Asymmetric dimethylarginine is negatively correlated with hyperglycemia in children.
    Endocrine journal, 2015, Volume: 62, Issue:6

    Topics: Adolescent; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hyperglycemia; Japan; Male; Pediatric Obesity; Risk

2015
The relationship between serum asymmetric dimethylarginine levels and subjective sleep quality in normotensive patients with type 2 diabetes mellitus.
    The Korean journal of internal medicine, 2015, Volume: 30, Issue:3

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors; Sleep; Sleep Wake Disorders; Surveys and Questionnaires

2015
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics.
    Bioanalysis, 2015, Volume: 7, Issue:10

    Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry

2015
The effect of nephropathy on plasma sphingosine 1-phosphate concentrations in patients with type 2 diabetes.
    Clinical biochemistry, 2015, Volume: 48, Issue:18

    Topics: Albuminuria; Apolipoproteins; Apolipoproteins M; Arginine; Biological Transport; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Lipocalins; Lysophospholipids; Male; Middle Aged; Sphingosine; Triglycerides

2015
ADMA: a specific biomarker for pathologic progress in diabetic microvascular complications?
    Biomarkers in medicine, 2016, Volume: 10, Issue:4

    Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prediabetic State; ROC Curve; Tandem Mass Spectrometry

2016
Serum asymmetric dimethylarginine and arginine levels predict microvascular and macrovascular complications in type 2 diabetes mellitus.
    Diabetes/metabolism research and reviews, 2017, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxidative Stress; Prognosis; Prospective Studies; Risk Factors; Young Adult

2017
Asymmetrical dimethyl arginine in type 2 diabetic patients with coronary artery disease.
    JPMA. The Journal of the Pakistan Medical Association, 2016, Volume: 66, Issue:8

    Topics: Adult; Arginine; Blood Glucose; Case-Control Studies; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Triglycerides

2016
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.
    Scientific reports, 2016, 10-18, Volume: 6

    Topics: Aminoisobutyric Acids; Animals; Arginine; Cardiovascular Diseases; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk; RNA, Small Interfering; Transaminases

2016
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:3

    Topics: Arginine; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Metabolic Syndrome

2009
Asymmetric dimethylarginine is closely associated with the development and progression of nephropathy in patients with type 2 diabetes.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:6

    Topics: Adult; Aged; Albuminuria; Arginine; Biomarkers; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Japan; Male; Middle Aged; Nitric Oxide Synthase; Prognosis; Proportional Hazards Models; Prospective Studies

2009
Relationship between cerebral arterial pulsatility and carotid intima media thickness in diabetic and non-diabetic patients with non-alcoholic fatty liver disease.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:1

    Topics: Aged; Arginine; Basilar Artery; Carotid Arteries; Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Male; Middle Aged; Pulsatile Flow; Tunica Intima; Tunica Media; Ultrasonography

2009
Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase.
    Journal of hypertension, 2010, Volume: 28, Issue:4

    Topics: Animals; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelial Cells; Glycation End Products, Advanced; Hypoglycemic Agents; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Vascular Diseases; Vasodilation; Vasodilator Agents

2010
Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes.
    PloS one, 2010, Mar-01, Volume: 5, Issue:3

    Topics: Aged; Amidohydrolases; Arginine; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Genotype; Haplotypes; Humans; Male; Mass Spectrometry; Middle Aged; Polymorphism, Genetic

2010
ADMA is a correlate of insulin resistance in early-stage diabetes independent of hs-CRP and body adiposity.
    Annales d'endocrinologie, 2010, Volume: 71, Issue:4

    Topics: Adiposity; Adult; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Diabetes Mellitus, Type 2; Fasting; Homeostasis; Humans; Inflammation; Insulin Resistance; Male; Middle Aged; Triglycerides

2010
Relationships between dimethylarginine and the presence of vertebral fractures in type 2 diabetes mellitus.
    Clinical endocrinology, 2010, Volume: 73, Issue:4

    Topics: Adult; Aged; Arginine; Bone Density; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Risk Factors; Spinal Fractures

2010
Chitotriosidase activity predicts endothelial dysfunction in type-2 diabetes mellitus.
    Endocrine, 2010, Volume: 37, Issue:3

    Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Endothelium; Female; Hexosaminidases; Humans; Male; Middle Aged; Young Adult

2010
Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus.
    Clinical endocrinology, 2011, Volume: 74, Issue:4

    Topics: Aged; Arginine; Asian People; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Regression Analysis; Risk Factors

2011
The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study.
    Cardiovascular diabetology, 2011, Feb-09, Volume: 10

    Topics: Aged; Amidohydrolases; Analysis of Variance; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cohort Studies; Coronary Angiography; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Insulin; Insulin Resistance; Kaplan-Meier Estimate; Linear Models; Linkage Disequilibrium; Logistic Models; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Taiwan

2011
Quantitation of L-arginine and asymmetric dimethylarginine in human plasma by LC-selective ion mode-MS for Type 2 diabetes mellitus study.
    Chemical & pharmaceutical bulletin, 2011, Volume: 59, Issue:7

    Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged

2011
Levels of soluble advanced glycation end product-receptors and other soluble serum markers as indicators of diabetic neuropathy in the foot.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2011, Volume: 59, Issue:8

    Topics: Aged; Arginine; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Foot; Diabetic Neuropathies; Glycated Hemoglobin; Humans; Male; Middle Aged; Nitric Oxide; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility

2011
Changes of skin temperature of parts of the body and serum asymmetric dimethylarginine (ADMA) in type-2 diabetes mellitus Indian patients.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2011, Volume: 2011

    Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; India; Infrared Rays; Male; Microcirculation; Middle Aged; Risk; Risk Assessment; Skin Temperature; Temperature; Thermography

2011
The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes.
    Gene, 2012, Apr-25, Volume: 498, Issue:1

    Topics: Adult; Arginine; C-Reactive Protein; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; HSP70 Heat-Shock Proteins; Humans; Inflammation Mediators; Male; Middle Aged; Nitric Oxide

2012
Relationship between plasma asymmetric dimethylarginine level and autonomic dysfunction in diabetic patients.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2012, Volume: 40, Issue:2

    Topics: Administration, Oral; Arginine; Autonomic Nervous System Diseases; Case-Control Studies; Diabetes Mellitus, Type 2; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged

2012
Chronic renal impairment and DDAH2-1151 A/C polymorphism determine ADMA levels in type 2 diabetic subjects.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:4

    Topics: Aged; Amidohydrolases; Arginine; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Kidney Function Tests; Male; Middle Aged; Nitric Oxide; Polymorphism, Genetic; Prognosis; Renal Insufficiency, Chronic; Risk Factors

2013
Asymmetric dimethylarginine and carotid atherosclerosis in Type 2 diabetes mellitus.
    Journal of endocrinological investigation, 2012, Volume: 35, Issue:9

    Topics: Adult; Aged; Arginine; Carotid Artery Diseases; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Prognosis

2012
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
    Kidney & blood pressure research, 2012, Volume: 36, Issue:1

    Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors

2012
Asymmetric dimethylarginine plasma levels and endothelial function in newly diagnosed type 2 diabetic patients.
    International journal of molecular sciences, 2012, Oct-24, Volume: 13, Issue:11

    Topics: Arginine; Blood Pressure; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Risk Factors

2012
Angiotensin-converting enzyme activity is involved in the mechanism of increased endogenous nitric oxide synthase inhibitor in patients with type 2 diabetes mellitus.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:9

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Immunoassay; Male; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Perindopril; Renin-Angiotensin System; von Willebrand Factor

2002
Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:3

    Topics: Aged; Arginine; Blood Glucose; Blood Pressure; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Insulin; Linear Models; Male; Middle Aged; Risk Factors; Triglycerides

2003
Effect of diabetic duration on serum concentrations of endogenous inhibitor of nitric oxide synthase in patients and rats with diabetes.
    Life sciences, 2005, May-27, Volume: 77, Issue:2

    Topics: Adult; Aged; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors; Vasoconstriction

2005
Serum asymmetric dimethylarginine as a marker of coronary microcirculation in patients with non-insulin dependent diabetes mellitus: correlation with coronary flow reserve.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:12

    Topics: Aged; Arginine; Biomarkers; Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Microcirculation; Regression Analysis

2005
Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes.
    Atherosclerosis, 2006, Volume: 189, Issue:1

    Topics: Aged; Arginine; Arterial Occlusive Diseases; Biomarkers; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Homocysteine; Humans; Hypoglycemic Agents; Incidence; Male; Middle Aged; Nitric Oxide Synthase; Prognosis; Risk Factors; Severity of Illness Index

2006
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Benzimidazoles; Benzoates; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Endothelium, Vascular; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency; Telmisartan; Tetrazoles; Valine; Valsartan

2005
Intensive treatment of risk factors in patients with type-2 diabetes mellitus is associated with improvement of endothelial function coupled with a reduction in the levels of plasma asymmetric dimethylarginine and endogenous inhibitor of nitric oxide synt
    European heart journal, 2006, Volume: 27, Issue:10

    Topics: Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Humans; Hyperglycemia; Male; Middle Aged; Nitric Oxide Synthase; Risk Factors; Tumor Necrosis Factor-alpha

2006
Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes.
    Diabetes care, 2007, Volume: 30, Issue:7

    Topics: Aged; Arginine; C-Reactive Protein; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Assessment

2007
Soluble RAGE in type 2 diabetes: association with oxidative stress.
    Free radical biology & medicine, 2007, Aug-15, Volume: 43, Issue:4

    Topics: Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dinoprost; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2007
Impaired vascular nitric oxide bioactivity in women with previous gestational diabetes.
    Wiener klinische Wochenschrift, 2007, Volume: 119, Issue:15-16

    Topics: Adult; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diabetic Angiopathies; Endothelium, Vascular; Female; Humans; Insulin Resistance; Male; Nitric Oxide; Obesity; Pregnancy; Reference Values; Risk Factors; Sex Factors; Vasoconstriction; Vasodilation

2007
Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus.
    International journal of cardiology, 2009, Feb-20, Volume: 132, Issue:2

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Coronary Circulation; Diabetes Mellitus, Type 2; Female; Humans; Male; Thiazepines

2009
Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus.
    The American journal of cardiology, 2001, Nov-15, Volume: 88, Issue:10

    Topics: Arginine; Blood Glucose; Case-Control Studies; Cholesterol; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase

2001