Page last updated: 2024-09-03

n,n-dimethylarginine and Coronary Artery Disease

n,n-dimethylarginine has been researched along with Coronary Artery Disease in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.32)18.2507
2000's26 (34.21)29.6817
2010's43 (56.58)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
Lazaros, G; Oikonomou, E; Papageorgiou, N; Sagris, M; Theofilis, P; Tousoulis, D1
Chen, YY; Huang, SS; Huang, WC; Lee, SH; Lu, TM; Tsai, CT1
Ball, RL; Cooke, JP; Kimura, T; Kobayashi, Y; Pargaonkar, V; Parikh, RV; Tremmel, JA; Yeung, AC1
Bartha, E; Molnar, T; Nagy, L; Szabo, Z1
Alhussini, K; Bening, C; Benitez, RC; Keller, D; Leyh, R; Madrahimov, N; Radakovic, D; Sales, VL1
Dai, Y; Mao, H; Ye, J; Zhang, J; Zheng, W1
Cohen, G; Fearon, WF; Khush, KK; Kobayashi, Y; Lee, JH; Luikart, H; Pargaonkar, VS; Parikh, RV; Sinha, S; Valantine, HA; Yeung, AC1
Eha, J; Jakobson, M; Kals, J; Lieberg, J; Ottas, A; Paapstel, K; Piir, A; Tootsi, K; Zilmer, M1
Buszman, E; Jasik, K; Rzepecka-Stojko, A; Stojko, J1
Ayati, N; Elyasi, S; Ghayour-Mobarhan, M; Mohammadpour, AH; Moohebati, M; Sahebkar, A1
Abdel Rahman, MF; Amir, M; Gad, MZ; Hassanein, SI1
Chyrchel, B; Hanff, E; Kuźniewski, M; Surdacki, A; Tsikas, D; Wieczorek-Surdacka, E1
Bleie, O; Borgeraas, H; Løland, KH; Nordrehaug, JE; Nygård, O; Strand, E; Svardal, A; Ueland, PM1
George, R; Gopu, CL; Hari, PR; Harikrishnan, S; Sreenivasan, K1
Golay, A; Kruszelnicka, O; Surdacki, A1
Başaran, Y; Geçmen, Ç; Gürel, E; Karaahmet, T; Mutlu, B; Tigen, K1
Alexopoulos, D; Bouras, G; Cleman, MW; Deftereos, G; Deftereos, S; Giannopoulos, G; Hatzis, G; Ioannidis, A; Kaoukis, A; Kossyvakis, C; Manolis, AS; Panagopoulou, V; Papadimitriou, C; Raisakis, K; Stefanadis, C; Tsounis, D1
Ahmadi, Y; Badalzadeh, R; Faghfoori, Z; Ghavimi, H; Jabbarpour, M; Karami, H; Majidinia, M; Samadi, N; Shafiei-Irannejad, V; Yousefi, B1
Huang, YH; Kuo, HC; Lee, CP; Tain, YL1
Adachi, T; Hakuno, D; Kimura, K; Kujiraoka, T; Masaki, N; Miyazaki, K; Namba, T; Shiraishi, Y; Toya, T; Yada, H1
Akyurek, F; Erdem, SS; Kiyici, A; Ozturk, B; Sivrikaya, A; Ugurcu, V; Unlu, A; Vatansev, H1
Das, UN1
Frölich, JC; Hahn, A; Kayacelebi, AA; Pham, VV; Rothmann, S; Schneider, JY; Tsikas, D; Willers, J1
Acar, Z; Can, F; Çiftçi, Ç; Civan, M; Erdem, Ş; Görmüş, U; Şahin, S; Ziyrek, M1
Chyrchel, B; Golay, A; Kruszelnicka, O; Surdacki, A1
He, GW; Li, H; Lun, LM; Tian, QW; Xuan, C; Zhang, BB1
Bosco, G; Bucciarelli, T; Bucciarelli, V; Di Ilio, E; Guagnano, MT; Martini, F; Riccioni, G; Scotti, L; Speranza, L1
Ise, T; Iwase, T; Kitaoka, A; Kusunose, K; Niki, T; Sata, M; Soeki, T; Taketani, Y; Tobiume, T; Wakatsuki, T; Yagi, S; Yamada, H; Yamaguchi, K; Yamazaki, H1
Atzler, D; Chobanyan-Jürgens, K; Choe, CU; Frölich, JC; Huneau, JF; Kayacelebi, AA; Langen, J; Lücke, T; Mariotti, F; Rothmann, S; Schneider, JY; Schwedhelm, E; Tsikas, D; Weigt-Usinger, K1
Aşik, M; Aslantaş, Y; Bulur, S; Doğan, AS; Erkan, ME; Ilçe, HT; Memişoğullari, R; Uçgun, T; Yildirim, M; Yildiz, N; Yilmaz, A1
Atarashi, H; Kohashi, K; Kosugi, M; Kusama, Y; Morisawa, T; Nakagomi, A; Shimizu, W1
Berge, RK; Bohov, P; Borgeraas, H; Hertel, JK; Hjelmesæth, J; Nygård, O; Seifert, R; Ueland, PM1
Bednarek, J; Chyrchel, B; Kruszelnicka, O; Nessler, J; Surdacki, A; Świerszcz, J1
Ambrosio, G; Cvetkovic, T; Ilic, MD; Ilic, S; Kocic, G; Lazarevic, G; Pavlovic, R; Zivanovic, S1
Bai, Y; Cao, R; Chen, Y; Du, G; He, G; Sun, L; Sun, T; Wang, F; Ye, P; Zhang, W; Zhao, R1
Barbato, E; Bartunek, J; Conte, M; De Bruyne, B; Delrue, L; Demartini, C; Di Sciascio, G; Dierickx, K; Mangiacapra, F; Muller, O; Trimarco, B; Wijns, W1
Khan, MA; Tariq, K1
Guo, FF; He, GW; Liu, ZF; Lun, LM; Wang, Q; Xuan, C; Zhang, X1
Hidekazu, M; Ikee, R; Kobayashi, S; Maesato, K; Mano, T; Ohtake, T; Oka, M1
Kristofova, B; Valocik, G; Valocikova, I1
Antoniades, C; Antonopoulos, A; Channon, KM; Cunnington, C; Leeson, P; Pillai, R; Ratnatunga, C; Shirodaria, C; Stefanadis, C; Tousoulis, D; Van-Assche, T; Warrick, N1
Coppola, JT; Deshmukh, SH; Hermance, EV; Infantino, MN; Mindrescu, C; Patel, SR; Pinassi, E; Staniloae, CS1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z1
Huang, Y; Li, J; Luo, X; Phillips, MI; Shi, H; Sun, T; Zhu, J1
Aktoz, M; Aktoz, T; Altun, A; Atakan, IH; Barutcu, A; Demir, M; Kaplan, M; Tatlı, E; Turan, FN1
Ding, H; Hui, R; Lu, Z; Shaffer, JR; Wang, DW; Wang, H; Wang, X; Wu, B; Yan, J1
Bentley, P; Sharma, P1
Bai, YP; Chen, L; Chen, XP; Guo, YJ; Li, L; Li, YJ; Sun, J; Xia, J; Yang, TL; Zhang, GG1
Bauersachs, J; Ertl, G; Fiedler, J; Fleissner, F; Galuppo, P; Gupta, SK; Jazbutyte, V; Kneitz, S; Mayr, M; Thum, T; Xu, Q; Yin, X1
Ardic, I; Celik, A; Ceyhan, K; Erdem, S; Kadi, H; Kalay, N; Kaya, MG; Koc, F; Onalan, O; Ozbek, K; Sahin, S; Taner, A; Yarlioglues, M1
Anker, SD; Bauersachs, J; Ertl, G; Lorenzen, JM; Stein, S; Störk, S; Thum, T; Tsikas, D; Weidemann, F; Wolf, C1
Ajtay, Z; Alotti, N; Bode-Böger, SM; Cziráki, A; Lenkey, Z; Martens-Lobenhoffer, J; Németh, Á; Sulyok, E; Szabados, S; Szabó, C1
Berkheimer, SB; Jang, JJ; Krishnaswami, A; Merchant, M1
Barutcuoğlu, B; Bayındır, O; Işıklar, OO; Kabaroğlu, C; Mutaf, I; Özmen, D; Uluer, H; Zoghi, M1
Cooke, JP; Weis, M1
Charng, MJ; Ding, YA; Lin, SJ; Lu, TM1
Cooke, JP; Gao, SZ; Kledal, TN; Lin, KY; Mocarski, ES; Panchal, SN; Valantine, HA; Weis, M1
Ritz, E1
Nishio, I; Tsuda, K1
Bae, SW; Choi, BY; Choi, YH; Lee, SH; Lee, YS; Pachinger, O; Park, HK; Park, JE; Stühlinger, MC; Yoo, HS; Yu, KH1
Cooke, JP; Gunawan, F; Jacobi, J; Robbins, RC; Sydow, K; Tanaka, M; Tsao, PS1
Anker, SD; Bauersachs, J; Eigenthaler, M; Ertl, G; Poole-Wilson, PA; Schultheiss, M; Stein, S; Thum, T; Tsikas, D1
Daimon, M; Hasegawa, R; Himi, T; Kawata, T; Komuro, I; Sekine, T; Teramoto, K; Toyoda, T; Uchida, D; Yamamoto, K; Yoshida, K1
Elesber, AA; Lennon, RJ; Lerman, A; Lerman, LO; Mathew, V; McConnell, JP; Nelson, RE; Prasad, A; Pumper, G; Solomon, H1
Böger, RH; Lüscher, TF; Maas, R; Quitzau, K; Rafflenbeul, W; Schwedhelm, E; Spieker, L; Steenpass, A1
Bauersachs, J; Becker, T; Beckmann, B; Chobanyan, K; Gutzki, FM; Mitschke, A; Pham, VV; Stichtenoth, DO; Thum, T; Tsikas, D1
Biberoglu, G; Cengel, A; Hasanoglu, A; Sahinarslan, A; Timurkaynak, T; Turkoglu, S1
Ambrose, J; Bernaski, E; Coppola, J; El-Khally, Z; Kurian, D; Mandadi, V; Morlote, M; Pinassi, E; Staniloae, C1
Bode-Böger, SM; Dubiel, JS; Huszno, B; Kawecka-Jaszcz, K; Klecha, A; Martens-Lobenhoffer, J; Stochmal, A; Stochmal, E; Surdacki, A; Szurkowska, M; Szybiński, Z1
Cooke, JP; Kielstein, JT1
Auer, J; Böger, RH; Eber, B; Lamm, G; Lassnig, E; Maas, R; O'Rourke, MF; Rammer, M; Weber, T1
Cooke, JP; Husson, G; Iribarren, C; Sidney, S; Sydow, K; Wang, BY1
Frøbert, O; Hjortshøj, SP; Ravkilde, J; Simonsen, U1
Akar, JG; Arab, D; Dieter, RS; Fareed, J; Hoppenstead, D; Joyal, D; Lewis, B; Leya, F; Morshedi-Meibodi, A; Obada Al-Chekakie, M; Steen, L1
Moriatis, M; Naidoo, D; Salonikas, C; Sim, AS; Wang, J; Wang, XL; Wilcken, DE1
Cooke, JP; Imaizumi, T; Matsuoka, H; Miyazaki, H; Okuda, S; Ueda, S; Usui, M1

Reviews

6 review(s) available for n,n-dimethylarginine and Coronary Artery Disease

ArticleYear
Prognostic value of asymmetric dimethylarginine in patients with coronary artery disease: A meta-analysis.
    Nitric oxide : biology and chemistry, 2021, 05-01, Volume: 109-110

    Topics: Arginine; Biomarkers; Coronary Artery Disease; Humans; Prognosis

2021
Nutritional factors in the prevention and management of coronary artery disease and heart failure.
    Nutrition (Burbank, Los Angeles County, Calif.), 2015, Volume: 31, Issue:2

    Topics: Alprostadil; Anti-Inflammatory Agents; Arginine; CD59 Antigens; Coronary Artery Disease; Diabetes Mellitus, Type 2; Epoprostenol; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Folic Acid; Heart Failure; Humans; Hypertension; Lipoxins; Magnesium; Male; Middle Aged; Nitric Oxide; Nutritional Status; Serum Albumin; Vasodilation; Vitamin B 12; Vitamin B 6

2015
Levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, and risk of coronary artery disease: A meta-analysis based on 4713 participants.
    European journal of preventive cardiology, 2016, Volume: 23, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Prognosis; Risk Assessment; Risk Factors; Up-Regulation

2016
Cardiac biomarkers and chronic renal diseases.
    Bratislavske lekarske listy, 2008, Volume: 109, Issue:8

    Topics: Animals; Arginine; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Disease Progression; Homocysteine; Humans; Kidney Failure, Chronic; Natriuretic Peptide, Brain; Troponin

2008
Cardiac allograft vasculopathy and dysregulation of the NO synthase pathway.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, Apr-01, Volume: 23, Issue:4

    Topics: Animals; Arginine; Cardiovascular Agents; Coronary Artery Disease; Endothelium, Vascular; Graft Rejection; Heart Transplantation; Humans; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Postoperative Complications; Rabbits; Transplantation, Homologous; Vasodilation; Vasomotor System

2003
Atherosclerosis in dialyzed patients.
    Blood purification, 2004, Volume: 22, Issue:1

    Topics: Anemia; Animals; Arginine; Arteriosclerosis; Biomarkers; Cause of Death; Comorbidity; Coronary Artery Disease; Diabetes Mellitus; Europe; Humans; Hyperlipidemias; Hypertension; Inflammation; Kidney Failure, Chronic; Mice; Mice, Knockout; Nitric Oxide; Phosphates; Renal Dialysis

2004

Trials

8 trial(s) available for n,n-dimethylarginine and Coronary Artery Disease

ArticleYear
Impact of Asymmetric Dimethylarginine on Coronary Physiology Early After Heart Transplantation.
    The American journal of cardiology, 2017, Sep-15, Volume: 120, Issue:6

    Topics: Arginine; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Follow-Up Studies; Fractional Flow Reserve, Myocardial; Heart Transplantation; Humans; Male; Microcirculation; Middle Aged; Prognosis; Prospective Studies; Time Factors; Vascular Resistance

2017
The association between progression of atherosclerosis and the methylated amino acids asymmetric dimethylarginine and trimethyllysine.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenosine; Aged; Arginine; Coronary Angiography; Coronary Artery Disease; Disease Progression; Ethionine; Female; Folic Acid; Follow-Up Studies; Humans; Lysine; Male; Methylation; Middle Aged; Treatment Outcome; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2013
Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Aged; Arginine; Arthritis, Rheumatoid; Coronary Artery Disease; Female; Homoarginine; Homocysteine; Humans; Male; Middle Aged; Peripheral Arterial Disease

2015
Differential associations of circulating asymmetric dimethylarginine and cell adhesion molecules with metformin use in patients with type 2 diabetes mellitus and stable coronary artery disease.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Aged; Aged, 80 and over; Arginine; Cell Adhesion Molecules; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Metformin; Middle Aged; Time Factors

2015
Impact of Indoxyl Sulfate, a Uremic Toxin, on Non-Culprit Coronary Plaque Composition Assessed on Integrated Backscatter Intravascular Ultrasound.
    Circulation journal : official journal of the Japanese Circulation Society, 2015, Volume: 79, Issue:8

    Topics: Aged; Arginine; Biomarkers; Coronary Artery Disease; Female; Humans; Indican; Male; Middle Aged; Plaque, Atherosclerotic; Risk Factors; Ultrasonography, Interventional

2015
Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free L-arginine in humans.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Amidinotransferases; Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Child; Coronary Artery Disease; Developmental Disabilities; Female; Guanidinoacetate N-Methyltransferase; Homoarginine; Humans; Intellectual Disability; Language Development Disorders; Male; Mice; Mice, Knockout; Middle Aged; Movement Disorders; Peripheral Arterial Disease; Speech Disorders

2015
Ranolazine improves endothelial function in patients with stable coronary artery disease.
    Coronary artery disease, 2009, Volume: 20, Issue:5

    Topics: Acetanilides; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Agents; Coronary Artery Disease; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hyperemia; Inflammation Mediators; Male; Manometry; Middle Aged; Piperazines; Ranolazine; Time Factors; Treatment Outcome; Vasodilation

2009
Pioglitazone improves endothelial function in non-diabetic patients with coronary artery disease.
    Cardiology, 2007, Volume: 108, Issue:3

    Topics: Adult; Aged; Arginine; Blood Sedimentation; Brachial Artery; C-Reactive Protein; Cardiovascular Agents; Coronary Artery Disease; Endothelium, Vascular; Fibrinogen; Humans; Lipids; Male; Middle Aged; Pioglitazone; PPAR gamma; Prospective Studies; Thiazolidinediones

2007

Other Studies

62 other study(ies) available for n,n-dimethylarginine and Coronary Artery Disease

ArticleYear
Asymmetric Dimethylarginine as a Biomarker in Coronary Artery Disease.
    Current topics in medicinal chemistry, 2023, Volume: 23, Issue:6

    Topics: Arginine; Atherosclerosis; Biomarkers; Coronary Artery Disease; Humans; Risk Factors

2023
Plasma asymmetric dimethylarginine is associated with vulnerable plaque and long-term outcomes in stable coronary artery disease.
    Scientific reports, 2023, 05-09, Volume: 13, Issue:1

    Topics: Calcium; Calcium, Dietary; Coronary Artery Disease; Humans; Lipids; Percutaneous Coronary Intervention; Plaque, Amyloid; Plaque, Atherosclerotic

2023
Asymmetric dimethylarginine predicts impaired epicardial coronary vasomotion in patients with angina in the absence of obstructive coronary artery disease.
    International journal of cardiology, 2020, 01-15, Volume: 299

    Topics: Angina Pectoris; Arginine; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Vasomotor System

2020
Increased symmetric dimethylarginine, but not asymmetric dimethylarginine, concentrations are associated with transient myocardial ischemia and predict outcome.
    The Journal of international medical research, 2020, Volume: 48, Issue:6

    Topics: Aged; Arginine; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Dipyridamole; Female; Follow-Up Studies; Heart; Heart Function Tests; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Prospective Studies; Risk Assessment; Tomography, X-Ray Computed

2020
Clinically inapparent right heart dysfunction is associated with reduced myofilament force development in coronary artery disease.
    BMC cardiovascular disorders, 2021, 03-05, Volume: 21, Issue:1

    Topics: Aged; Arginine; Asymptomatic Diseases; Biomarkers; C-Reactive Protein; Calcium; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Myocardial Contraction; Myofibrils; Serum Albumin, Human; Serum Amyloid P-Component; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Function, Right

2021
Inverse relations of serum phosphatidylcholines and lysophosphatidylcholines with vascular damage and heart rate in patients with atherosclerosis.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2018, Volume: 28, Issue:1

    Topics: Aged; Angiography, Digital Subtraction; Arginine; Biomarkers; Case-Control Studies; Coronary Artery Disease; Cross-Sectional Studies; Endothelium, Vascular; Heart Rate; Humans; Lysophosphatidylcholines; Male; Metabolomics; Middle Aged; Peripheral Arterial Disease; Phosphatidylcholines; Pulse Wave Analysis; Vascular Stiffness

2018
Anti-Atherogenic Activity of Polyphenol-Rich Extract from Bee Pollen.
    Nutrients, 2017, Dec-18, Volume: 9, Issue:12

    Topics: Angiotensin II; Animals; Arginine; Atherosclerosis; Bees; Cholesterol; Coronary Artery Disease; Diet, High-Fat; Dose-Response Relationship, Drug; Female; Hypercholesterolemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Peptidyl-Dipeptidase A; Pollen; Polyphenols

2017
Evaluation of serum Asymmetric Dimethyl Arginine concentrations in coronary artery disease patients without traditional cardiovascular risk factors.
    Acta bio-medica : Atenei Parmensis, 2018, 06-07, Volume: 89, Issue:2

    Topics: Arginine; Biomarkers; Case-Control Studies; Coronary Artery Disease; Coronary Stenosis; Female; Humans; Male; Middle Aged

2018
AGXT2 and DDAH-1 genetic variants are highly correlated with serum ADMA and SDMA levels and with incidence of coronary artery disease in Egyptians.
    Molecular biology reports, 2018, Volume: 45, Issue:6

    Topics: Adult; Amidohydrolases; Arginine; Case-Control Studies; Coronary Artery Disease; Egypt; Female; Genetic Variation; Genotype; Humans; Incidence; Male; Middle Aged; Nitric Oxide; Polymorphism, Single Nucleotide; Transaminases

2018
Distinct associations between plasma osteoprotegerin, homoarginine and asymmetric dimethylarginine in chronic kidney disease male patients with coronary artery disease.
    Amino acids, 2019, Volume: 51, Issue:6

    Topics: Aged; Arginine; Biomarkers; Coronary Artery Disease; Homoarginine; Humans; Male; Middle Aged; Osteoprotegerin; Renal Insufficiency, Chronic

2019
Simultaneous determination of homocysteine and asymmetric dimethylarginine in human urine by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, Nov-15, Volume: 939

    Topics: Arginine; Biomarkers; Chromatography, Liquid; Coronary Artery Disease; Homocysteine; Humans; Limit of Detection; Linear Models; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2013
Differential associations of angiographic extent and severity of coronary artery disease with asymmetric dimethylarginine but not insulin resistance in non-diabetic men with stable angina: a cross-sectional study.
    Cardiovascular diabetology, 2013, Oct-09, Volume: 12

    Topics: Adult; Aged; Angina, Stable; Arginine; Biomarkers; Blood Glucose; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Humans; Insulin; Insulin Resistance; Linear Models; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Risk Factors; Severity of Illness Index

2013
Predictive value of plasma asymmetric dimethylarginine, homocysteine, and high-sensitive CRP levels in occult coronary artery disease: A multidetector-row computed tomography study.
    Herz, 2015, Volume: 40, Issue:3

    Topics: Arginine; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Female; Homocysteine; Humans; Male; Middle Aged; Multidetector Computed Tomography; Prognosis; Reproducibility of Results; Risk Assessment; Sensitivity and Specificity

2015
Association of asymmetric dimethylarginine levels with treadmill-stress-test-derived prognosticators.
    Clinical biochemistry, 2014, Volume: 47, Issue:7-8

    Topics: Aged; Arginine; Biomarkers; Coronary Artery Disease; Exercise Test; Female; Humans; Male; Middle Aged; Prognosis; Risk Factors

2014
The effects of Ramadan fasting on endothelial function in patients with cardiovascular diseases.
    European journal of clinical nutrition, 2014, Volume: 68, Issue:7

    Topics: Adult; Arginine; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Artery Disease; Endothelium, Vascular; Fasting; Humans; Islam; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Peripheral Arterial Disease; Vascular Endothelial Growth Factor A

2014
Asymmetric and symmetric dimethylarginine are associated with coronary artery lesions in Kawasaki disease.
    The Journal of pediatrics, 2014, Volume: 165, Issue:2

    Topics: Arginine; Biomarkers; Child, Preschool; Coronary Artery Disease; Coronary Vessels; Female; Humans; Immunoglobulins, Intravenous; Infant; Male; Mucocutaneous Lymph Node Syndrome

2014
Association between brachial-ankle pulse wave velocity and the ratio of l-arginine to asymmetric dimethylarginine in patients undergoing coronary angiography.
    Journal of cardiology, 2015, Volume: 65, Issue:4

    Topics: Aged; Ankle Brachial Index; Arginine; Blood Pressure; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Heart Rate; Hematocrit; Hemoglobins; Humans; Kidney; Male; Middle Aged; Natriuretic Peptide, Brain; Pulse Wave Analysis; Vascular Stiffness

2015
Levels of arginine and its products in dialysis patients.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:16

    Topics: Adult; Aged; Arginine; Coronary Artery Disease; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide; Renal Dialysis

2014
The association between coronary atherosclerotic burden and asymmetric dimethylarginine, carotis intima media thickness and endothelial function.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2014, Volume: 42, Issue:8

    Topics: Aged; Arginine; Biomarkers; Brachial Artery; Carotid Intima-Media Thickness; Cholesterol; Cholesterol, LDL; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Severity of Illness Index; Triglycerides

2014
Physical exercise reduces synthesis of ADMA, SDMA, and L-Arg.
    Frontiers in bioscience (Elite edition), 2015, 06-01, Volume: 7, Issue:3

    Topics: Arginine; Biomarkers; Coronary Artery Disease; Exercise; Female; Humans; Male; Middle Aged; Nitric Oxide

2015
Asymmetric dimethylarginine is not a good predictor of ischemia using myocardial perfusion scintigraphy.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:4

    Topics: Arginine; Coronary Artery Disease; Echocardiography; Female; Humans; Ischemia; Male; Middle Aged; Myocardial Perfusion Imaging; Predictive Value of Tests; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon

2015
Osteoprotegerin is Associated With Endothelial Function and Predicts Early Carotid Atherosclerosis in Patients With Coronary Artery Disease.
    International heart journal, 2015, Volume: 56, Issue:6

    Topics: Aged; Arginine; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Coronary Angiography; Coronary Artery Disease; Early Diagnosis; Endothelium, Vascular; Female; Humans; Japan; Male; Middle Aged; Osteoprotegerin; Predictive Value of Tests; Risk Assessment; Risk Factors; Severity of Illness Index

2015
Serum trans fatty acids, asymmetric dimethylarginine and risk of acute myocardial infarction and mortality in patients with suspected coronary heart disease: a prospective cohort study.
    Lipids in health and disease, 2016, Feb-27, Volume: 15

    Topics: Aged; Arginine; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Trans Fatty Acids

2016
Asymmetric Dimethylarginine versus Proton Pump Inhibitors Usage in Patients with Stable Coronary Artery Disease: A Cross-Sectional Study.
    International journal of molecular sciences, 2016, Apr-15, Volume: 17, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Arginine; Coronary Artery Disease; Cross-Sectional Studies; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Humans; Male; Middle Aged; Omeprazole; Pantoprazole; Peptic Ulcer; Proton Pump Inhibitors; Treatment Outcome

2016
Detrimental effects of a bout of physical exercise on circulating endogenous inhibitors of endothelial function in patients with coronary artery disease.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2017, Volume: 18, Issue:8

    Topics: Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Coronary Artery Disease; Echocardiography; Exercise; Exercise Test; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Risk Factors; Young Adult

2017
Oncological miR-182-3p, a Novel Smooth Muscle Cell Phenotype Modulator, Evidences From Model Rats and Patients.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:7

    Topics: Animals; Arginine; Carotid Artery Diseases; Carotid Artery Injuries; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Artery Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Gene Expression Regulation; Humans; Male; MicroRNAs; Muscle, Smooth, Vascular; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myocytes, Smooth Muscle; Neointima; Oligonucleotide Array Sequence Analysis; Phenotype; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Transfection; Vascular Remodeling

2016
Relationship of asymmetric dimethylarginine (ADMA) with extent and functional severity of coronary atherosclerosis.
    International journal of cardiology, 2016, Oct-01, Volume: 220

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Severity of Illness Index

2016
Asymmetrical dimethyl arginine in type 2 diabetic patients with coronary artery disease.
    JPMA. The Journal of the Pakistan Medical Association, 2016, Volume: 66, Issue:8

    Topics: Adult; Arginine; Blood Glucose; Case-Control Studies; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Triglycerides

2016
Increased serum concentrations of asymmetric dimethylarginine (ADMA) in patients with early-onset coronary artery disease.
    Clinica chimica acta; international journal of clinical chemistry, 2017, Volume: 464

    Topics: Age of Onset; Arginine; Coronary Artery Disease; Coronary Vessels; Female; Humans; Male; Middle Aged; Risk

2017
Coronary artery calcification, ADMA, and insulin resistance in CKD patients.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:5

    Topics: Aged; Arginine; Calcinosis; Case-Control Studies; Chronic Disease; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Female; Glomerular Filtration Rate; Humans; Insulin Resistance; Kidney Diseases; Male; Middle Aged; Risk Assessment; Severity of Illness Index; Tomography, X-Ray Computed

2008
Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis.
    European heart journal, 2009, Volume: 30, Issue:9

    Topics: Aged; Arginine; Atherosclerosis; Coronary Artery Bypass; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Saphenous Vein; Superoxides; Vasodilation

2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Growth differentiation factor 15 and coronary collateral formation.
    Clinical cardiology, 2010, Volume: 33, Issue:1

    Topics: Aged; Analysis of Variance; Arginine; Collateral Circulation; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary Stenosis; Cross-Sectional Studies; Female; Growth Differentiation Factor 15; Humans; Male; Middle Aged; Prognosis; Statistics, Nonparametric; Vascular Endothelial Growth Factor Receptor-1

2010
Assessment of the relationship between asymmetric dimethylarginine and severity of erectile dysfunction and coronary artery disease.
    International urology and nephrology, 2010, Volume: 42, Issue:4

    Topics: Arginine; Coronary Artery Disease; Erectile Dysfunction; Humans; Male; Middle Aged; Severity of Illness Index; Surveys and Questionnaires

2010
A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease.
    Circulation research, 2010, Apr-02, Volume: 106, Issue:6

    Topics: Aged; Amidohydrolases; Arginine; Asian People; Binding Sites; Biomarkers; Case-Control Studies; Cells, Cultured; Chi-Square Distribution; China; Coronary Artery Disease; DNA Mutational Analysis; DNA-Binding Proteins; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mutagenesis, Insertional; Odds Ratio; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Assessment; Risk Factors; Sequence Deletion; Stroke; Thrombosis; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection

2010
Down but not out: candidate gene-based studies still have value in a world dominated by whole genome approaches.
    Circulation research, 2010, Apr-02, Volume: 106, Issue:6

    Topics: Amidohydrolases; Arginine; Asian People; Biomarkers; China; Coronary Artery Disease; Evidence-Based Medicine; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors; Stroke; Thrombosis

2010
The ALDH2 Glu504Lys polymorphism is associated with coronary artery disease in Han Chinese: Relation with endothelial ADMA levels.
    Atherosclerosis, 2010, Volume: 211, Issue:2

    Topics: Aged; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Arginine; China; Coronary Artery Disease; Endothelium, Vascular; Female; Glutamic Acid; Humans; Lysine; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors

2010
Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism.
    Circulation research, 2010, Jul-09, Volume: 107, Issue:1

    Topics: Angiogenesis Inhibitors; Arginine; Coronary Artery Disease; Gene Expression Regulation; Humans; MicroRNAs; Neovascularization, Pathologic; Stem Cells

2010
Relationship between L-arginine/asymmetric dimethylarginine, homocysteine, folic acid, vitamin B levels, and coronary artery ectasia.
    Coronary artery disease, 2010, Volume: 21, Issue:8

    Topics: Aged; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Dilatation, Pathologic; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Prospective Studies; Turkey; Vitamin B Complex

2010
Urinary asymmetric dimethylarginine (ADMA) is a predictor of mortality risk in patients with coronary artery disease.
    International journal of cardiology, 2012, May-03, Volume: 156, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Risk Factors

2012
Effects of coronary revascularization with or without cardiopulmonary bypass on plasma levels of asymmetric dimethylarginine.
    Coronary artery disease, 2011, Volume: 22, Issue:4

    Topics: Aged; Arginine; Biomarkers; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Coronary Artery Bypass; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Reperfusion Injury; Tandem Mass Spectrometry

2011
Asymmetric dimethylarginine and coronary artery calcium scores are increased in patients infected with human immunodeficiency virus.
    Atherosclerosis, 2011, Volume: 217, Issue:2

    Topics: Adult; Arginine; Biomarkers; Calcinosis; California; Case-Control Studies; Chi-Square Distribution; Coronary Angiography; Coronary Artery Disease; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Risk Assessment; Risk Factors; RNA, Viral; Tomography, X-Ray Computed; Up-Regulation

2011
Do cardiac risk factors affect the homocysteine and asymmetric dimethylarginine relationship in patients with coronary artery diseases?
    Clinical biochemistry, 2012, Volume: 45, Issue:16-17

    Topics: Adult; Aged; Arginine; Atherosclerosis; Coronary Artery Disease; Female; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Risk Factors

2012
Asymmetrical dimethylarginine: a novel risk factor for coronary artery disease.
    Clinical cardiology, 2003, Volume: 26, Issue:10

    Topics: Aged; Arginine; Biomarkers; Coronary Angiography; Coronary Artery Disease; Exercise Test; Female; Humans; Male; Multivariate Analysis; Nitric Oxide Synthase; Predictive Value of Tests; Prospective Studies; Risk Factors

2003
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis.
    Circulation, 2004, Feb-03, Volume: 109, Issue:4

    Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Cells, Cultured; Coronary Angiography; Coronary Artery Disease; Cyclic GMP; Cytomegalovirus Infections; Endothelium, Vascular; Female; Heart Transplantation; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Risk Factors; Signal Transduction

2004
Sex hormones and asymmetric dimethylarginine in transplant arteriosclerosis.
    Circulation, 2004, Jul-20, Volume: 110, Issue:3

    Topics: Arginine; Coronary Artery Disease; Endothelium, Vascular; Estrogens; Female; Gonadal Steroid Hormones; Heart Transplantation; Humans; Male

2004
Plasma asymmetric dimethylarginine concentrations in newly diagnosed patients with acute myocardial infarction or unstable angina pectoris during two weeks of medical treatment.
    The American journal of cardiology, 2005, Mar-15, Volume: 95, Issue:6

    Topics: Adult; Aged; alpha-Tocopherol; Angina, Unstable; Angioplasty, Balloon, Coronary; Arginine; C-Reactive Protein; Cardiovascular Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Coronary Angiography; Coronary Artery Disease; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Insulin; Lipoproteins, HDL; Male; Middle Aged; Myocardial Infarction; Statistics as Topic; Treatment Outcome; Triglycerides

2005
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease.
    Circulation, 2005, Sep-13, Volume: 112, Issue:11

    Topics: Amidohydrolases; Animals; Arginine; Coronary Artery Disease; Cytokines; Enzyme Inhibitors; Female; Heart; Heart Transplantation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocarditis; Myocardium; Nitrates; Nitric Oxide Synthase; Nitrites; Osmolar Concentration; Postoperative Period; Pregnancy; Superoxides; Time Factors; Transplantation, Heterotopic; Transplantation, Homologous; Tumor Necrosis Factor-alpha

2005
Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine.
    Journal of the American College of Cardiology, 2005, Nov-01, Volume: 46, Issue:9

    Topics: Arginine; Cell Count; Cells, Cultured; Coronary Artery Disease; Endothelium, Vascular; Enzyme Inhibitors; Humans; Stem Cells

2005
Serum asymmetric dimethylarginine as a marker of coronary microcirculation in patients with non-insulin dependent diabetes mellitus: correlation with coronary flow reserve.
    Heart (British Cardiac Society), 2005, Volume: 91, Issue:12

    Topics: Aged; Arginine; Biomarkers; Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Microcirculation; Regression Analysis

2005
Coronary endothelial dysfunction is associated with erectile dysfunction and elevated asymmetric dimethylarginine in patients with early atherosclerosis.
    European heart journal, 2006, Volume: 27, Issue:7

    Topics: Arginine; C-Reactive Protein; Coronary Artery Disease; Endothelium, Vascular; Erectile Dysfunction; Humans; Male; Middle Aged; Risk Factors

2006
Asymmetrical dimethylarginine (ADMA) and coronary endothelial function in patients with coronary artery disease and mild hypercholesterolemia.
    Atherosclerosis, 2007, Volume: 191, Issue:1

    Topics: Acetylcholine; Adenosine; Aged; Arginine; Coronary Artery Disease; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Nitroglycerin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2007
Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, May-15, Volume: 851, Issue:1-2

    Topics: Acetazolamide; Adult; Arginine; Benzamides; Circadian Rhythm; Coronary Artery Disease; Dimethylamines; Diuretics; Female; Gas Chromatography-Mass Spectrometry; Health; Humans; Liver Diseases; Male; Middle Aged; Quality Control; Time Factors; Urinalysis

2007
Plasma asymmetric dimethylarginine level and extent of lesion at coronary angiography.
    Coronary artery disease, 2006, Volume: 17, Issue:7

    Topics: Adolescent; Adult; Aged; Angina Pectoris; Arginine; Coronary Angiography; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk; Severity of Illness Index

2006
Nontraditional atherosclerotic risk factors and extent of coronary atherosclerosis in patients with combined impaired fasting glucose and impaired glucose tolerance.
    Metabolism: clinical and experimental, 2007, Volume: 56, Issue:1

    Topics: Adult; Aged; Arginine; Blood Glucose; C-Reactive Protein; Cholesterol; Coronary Artery Disease; Discriminant Analysis; Female; Glucose Clamp Technique; Homocysteine; Humans; Insulin Resistance; Male; Middle Aged; Risk Factors; Triglycerides

2007
Should we measure asymmetric dimethylarginine in patients with coronary artery disease?
    Clinical chemistry, 2007, Volume: 53, Issue:2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Coronary Artery Disease; Humans; Mortality; Predictive Value of Tests; Risk Factors

2007
Arterial wave reflections and determinants of endothelial function a hypothesis based on peripheral mode of action.
    American journal of hypertension, 2007, Volume: 20, Issue:3

    Topics: Age Factors; Aged; Aorta; Arginine; Blood Flow Velocity; Blood Pressure; Coronary Artery Disease; Cross-Sectional Studies; Elasticity; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Linear Models; Male; Manometry; Middle Aged; Predictive Value of Tests; Prospective Studies; Pulsatile Flow; Radial Artery

2007
Asymmetric dimethyl-arginine and coronary artery calcification in young adults entering middle age: the CARDIA Study.
    European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology, 2007, Volume: 14, Issue:2

    Topics: Adult; Analysis of Variance; Arginine; Biomarkers; Calcinosis; Case-Control Studies; Coronary Artery Disease; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Humans; Linear Models; Logistic Models; Male; Middle Aged; Research Design; Risk Factors; Tomography, X-Ray Computed; Treatment Outcome

2007
Methylated arginines in stable and acute patients with coronary artery disease before and after percutaneous revascularization.
    International journal of cardiology, 2008, Sep-26, Volume: 129, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Coronary Artery Disease; Endothelium; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nitric Oxide Synthase; Prospective Studies

2008
Presence of asymmetric dimethylarginine gradients across high-grade lesions in patients with coronary artery disease.
    Coronary artery disease, 2007, Volume: 18, Issue:6

    Topics: Aged; Angioplasty, Balloon, Laser-Assisted; Arginine; Atherosclerosis; Biomarkers; Coronary Artery Disease; Coronary Vessels; Endothelium, Vascular; Female; Humans; Male; Middle Aged

2007
Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease.
    Atherosclerosis, 2008, Volume: 197, Issue:2

    Topics: Age Factors; Aged; Arginine; Biomarkers; Cohort Studies; Coronary Artery Disease; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Homocysteine; Humans; Male; Middle Aged; Renal Insufficiency; Risk Factors

2008
[Endogenous nitric oxide synthase inhibitor: a novel marker of atherosclerosis].
    Journal of cardiology, 1999, Volume: 33, Issue:2

    Topics: Arginine; Biomarkers; Coronary Artery Disease; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase

1999