Page last updated: 2024-09-03

n,n-dimethylarginine and Cirrhosis

n,n-dimethylarginine has been researched along with Cirrhosis in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (14.29)29.6817
2010's13 (61.90)24.3611
2020's5 (23.81)2.80

Authors

AuthorsStudies
He, S; Huang, C; Jiang, J; Li, G; Li, N; Li, T; Niu, B; Tong, W; Wang, S; Wu, M; Wu, T; Yan, L1
Bełtowski, J; Czechowska, G; Fornal, E; Góralczyk, A; Korolczuk, A; Kozub, A; Marzec-Kotarska, B; Nikolaichuk, H; Pradiuch, A; Stachniuk, A; Trzpil, A; Wójcicka, G1
Awad, AS; Cooper, TK; Gao, T; Morris, SM; Stanley, K; Wetzel, MD1
Huang, D; Tan, B; Wang, C; Wang, Y; Wu, M; Ye, C; Yuan, M; Zou, Y1
Balasubramanyam, M; Jayachandran, I; Manickam, N; Mohan, V; Paadukaana, S; Sundararajan, S; Venkatesan, S1
Cao, J; Lei, T; Liu, S; Lu, Z; Shi, L; Wang, H; Zhao, C1
Atzler, D; Böger, RH; Chen, P; Chen, Y; Fassett, J; Guo, H; Hu, X; Kwak, D; Liu, X; Lu, Z; Schwedhelm, E; Wang, H; Xu, X; Yue, W; Zhang, P1
Duan, JL; Fu, H; Fu, XM; Hua, P; Li, WY; Liao, YQ; Wang, XC; Wu, XR; Xia, ZH; Xuan, W; Ye, JM; Ye, JY; Zhang, X; Zhu, ZD1
Huang, CY; Jiang, JL; Li, G; Zhao, WC1
Bartoszewicz, Z; Bienias, P; Ciurzyński, M; Demkow, U; Górska, E; Irzyk, K; Kostrubiec, M; Pruszczyk, P; Siwicka, M; Stelmaszczyk-Emmel, A1
Chen, YC; Huang, LT; Sheen, JM; Tain, YL1
Doyle, V; Givvimani, S; Kundu, S; Metreveli, N; Narayanan, N; Pushpakumar, S; Tyagi, SC; Veeranki, S; Winchester, LJ1
Parrish, AR1
Baylis, C; Croker, B; Cunningham, MW; Moningka, NC; Sasser, JM1
Bigé, N; Boffa, JJ; Chatziantoniou, C; Dussaule, JC; Jouanneau, C; Mihout, F; Ronco, P; Shweke, N1
Aizawa, K; Ishizuka, N; Iwabuchi, S; Kitamura, H; Moriguchi, Y; Nishimura, T; Serizawa, K; Tashiro, Y; Yogo, K; Yorozu, K1
Dahal, BK; Dumitrascu, R; Eickelberg, O; Ghofrani, HA; Grimminger, F; Guenther, A; Konigshoff, M; Leiper, J; Pullamsetti, SS; Savai, R; Schermuly, RT; Seeger, W; Weissmann, N; Wilhelm, J; Zakrzewicz, D1
Kokot, F; Kunsdorf-Wnuk, A; Wnuk, Z1
Del Olmo, JA; Lluch, P; Mauricio, MD; Medina, P; Rodrigo, JM; Segarra, G; Serra, MA; Vila, JM1
Fukami, K; Imaizumi, T; Matsuguma, K; Matsumoto, Y; Matsuoka, H; Okuda, S; Shibata, R; Ueda, S; Yamagishi, S1
Hasegawa, K; Hayashi, K; Homma, K; Itoh, H; Kimoto, M; Sugano, N; Tatematsu, S; Wakino, S; Yoshioka, K1

Reviews

3 review(s) available for n,n-dimethylarginine and Cirrhosis

ArticleYear
Asymmetric dimethylarginine: An crucial regulator in tissue fibrosis.
    European journal of pharmacology, 2019, Jul-05, Volume: 854

    Topics: Animals; Arginine; Fibrosis; Humans

2019
Increased circulatory asymmetric dimethylarginine and multiple organ failure: bile duct ligation in rat as a model.
    International journal of molecular sciences, 2014, Mar-05, Volume: 15, Issue:3

    Topics: Animals; Arginine; Bile Ducts; Disease Models, Animal; Fibrosis; Ligation; Liver; Liver Cirrhosis; Multiple Organ Failure; Rats

2014
The cytoskeleton as a novel target for treatment of renal fibrosis.
    Pharmacology & therapeutics, 2016, Volume: 166

    Topics: Actins; Animals; Arginine; Cytoskeleton; Disease Progression; Epithelial Cells; Fibrosis; Humans; Kidney Failure, Chronic; Podocytes; Renal Insufficiency, Chronic; rho-Associated Kinases

2016

Other Studies

18 other study(ies) available for n,n-dimethylarginine and Cirrhosis

ArticleYear
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway.
    European journal of pharmacology, 2023, Jul-05, Volume: 950

    Topics: Amidohydrolases; Animals; Arginine; Endothelial Cells; Fibrosis; Forkhead Box Protein O1; Glucose; Humans; Rats; RNA, Long Noncoding; Signal Transduction

2023
The effect of exenatide (a GLP-1 analogue) and sitagliptin (a DPP-4 inhibitor) on asymmetric dimethylarginine (ADMA) metabolism and selected biomarkers of cardiac fibrosis in rats with fructose-induced metabolic syndrome.
    Biochemical pharmacology, 2023, Volume: 214

    Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Chromatography, Liquid; Dipeptidyl-Peptidase IV Inhibitors; Exenatide; Fibrosis; Fructose; Glucagon-Like Peptide 1; Hypoglycemic Agents; Metabolic Syndrome; Nitric Oxide; Protease Inhibitors; Rats; Sitagliptin Phosphate; Tandem Mass Spectrometry

2023
Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy.
    American journal of physiology. Renal physiology, 2020, 02-01, Volume: 318, Issue:2

    Topics: Adenoviridae; Albuminuria; Amidohydrolases; Animals; Arginine; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Genetic Therapy; Genetic Vectors; Inflammation Mediators; Kidney; Male; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Thiobarbituric Acid Reactive Substances

2020
Renal asymmetric dimethylarginine inhibits fibrosis.
    FEBS open bio, 2020, Volume: 10, Issue:10

    Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Fibronectins; Fibrosis; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Renal Insufficiency, Chronic; Ureteral Obstruction

2020
Asymmetric dimethylarginine (ADMA) accelerates renal cell fibrosis under high glucose condition through NOX4/ROS/ERK signaling pathway.
    Scientific reports, 2020, 09-29, Volume: 10, Issue:1

    Topics: Animals; Arginine; Cell Line; Cell Movement; Cell Proliferation; Cells, Cultured; Diabetic Retinopathy; Fibroblasts; Fibrosis; Glucose; Kidney; MAP Kinase Signaling System; Mesangial Cells; Models, Biological; NADPH Oxidase 4; Rats; Reactive Oxygen Species

2020
Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
    Antioxidants & redox signaling, 2017, Dec-01, Volume: 27, Issue:16

    Topics: Aging; Aldosterone; Amidohydrolases; Animals; Arginine; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockout Techniques; Humans; Kidney Diseases; Kidney Tubules, Proximal; Mice

2017
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
    Basic research in cardiology, 2017, 08-17, Volume: 112, Issue:5

    Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Genetic Predisposition to Disease; Hypertrophy, Left Ventricular; Male; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide; Phenotype; Signal Transduction; Tyrosine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling

2017
DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats.
    International journal of molecular medicine, 2019, Volume: 43, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Cell Line; Diabetic Cardiomyopathies; Fibrosis; Male; Matrix Metalloproteinase 2; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Rats; Signal Transduction; Tissue Inhibitor of Metalloproteinase-2

2019
Serum endothelin-1 and NT-proBNP, but not ADMA, endoglin and TIMP-1 levels, reflect impaired right ventricular function in patients with systemic sclerosis.
    Clinical rheumatology, 2014, Volume: 33, Issue:1

    Topics: Adult; Aged; Antigens, CD; Arginine; Biomarkers; Case-Control Studies; Collagen; Echocardiography; Echocardiography, Doppler; Endoglin; Endothelin-1; Endothelium, Vascular; Female; Fibrosis; Humans; Lung Diseases; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Prospective Studies; Receptors, Cell Surface; Scleroderma, Systemic; Tissue Inhibitor of Metalloproteinase-1; Ventricular Function, Right

2014
Hyperhomocysteinemia: a missing link to dysfunctional HDL via paraoxanase-1.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:9

    Topics: Amidohydrolases; Animals; Arginine; Aryldialkylphosphatase; Atherosclerosis; Blood Pressure; Connexins; Diet, Atherogenic; Endothelium, Vascular; Fibrosis; Gap Junction alpha-4 Protein; Gap Junction alpha-5 Protein; Hyperhomocysteinemia; Lipoproteins, HDL; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Ventricular Dysfunction, Left

2015
Asymmetric dimethylarginine in angiotensin II-induced hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:3

    Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Fibrosis; Hypertension, Renal; Kidney Cortex; Male; NADPH Oxidases; Nitrates; Nitrites; Oxidative Stress; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vasoconstrictor Agents

2010
Asymmetric dimethylarginine (ADMA) induces chronic kidney disease through a mechanism involving collagen and TGF-β1 synthesis.
    The Journal of pathology, 2011, Volume: 223, Issue:1

    Topics: Animals; Arginine; Collagen; Endothelin-1; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidative Stress; Renal Insufficiency, Chronic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta1

2011
Left ventricular hypertrophy is associated with inflammation in sodium loaded subtotal nephrectomized rats.
    Biomedical research (Tokyo, Japan), 2011, Volume: 32, Issue:2

    Topics: Animals; Arginine; Creatinine; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Interleukin-6; Kidney Failure, Chronic; Male; Nephrectomy; Parathyroid Hormone; Phosphates; Rats; Rats, Wistar; Risk Factors; Sclerosis; Sodium Chloride

2011
The role of dimethylarginine dimethylaminohydrolase in idiopathic pulmonary fibrosis.
    Science translational medicine, 2011, Jun-15, Volume: 3, Issue:87

    Topics: Amidohydrolases; Animals; Antibiotics, Antineoplastic; Apoptosis; Arginine; Bleomycin; Cell Line; Cell Proliferation; Collagen; Female; Fibroblasts; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Isoenzymes; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nitric Oxide Synthase Type II; Random Allocation

2011
Diagnostic value of plasma asymmetric and symmetric dimethylarginine levels in liver transplant recipients.
    Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:7-8

    Topics: Alanine Transaminase; Arginine; Aspartate Aminotransferases; Biomarkers; Cadaver; Fibrosis; Humans; Kidney Transplantation; Predictive Value of Tests; Renal Insufficiency, Chronic

2012
Accumulation of symmetric dimethylarginine in hepatorenal syndrome.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:1

    Topics: Arginine; Case-Control Studies; Creatinine; Fibrosis; Hepatorenal Syndrome; Humans; Kidney; Liver; Male; Middle Aged; Nitric Oxide; Renal Insufficiency

2006
Dimethylarginine dimethylaminohydrolase prevents progression of renal dysfunction by inhibiting loss of peritubular capillaries and tubulointerstitial fibrosis in a rat model of chronic kidney disease.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:5

    Topics: Amidohydrolases; Animals; Arginine; Capillaries; Chronic Disease; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression Regulation, Enzymologic; Genetic Therapy; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta

2007
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.
    Circulation research, 2007, Jul-20, Volume: 101, Issue:2

    Topics: Amidohydrolases; Amlodipine; Angiotensin II; Animals; Arginine; Blood Pressure; Coronary Circulation; Coronary Vessels; Creatine Kinase, MB Form; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Heart Diseases; Imidazoles; Mice; Mice, Transgenic; Myocardium; Nitric Oxide; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Pyridines; Time Factors; Tunica Media; Up-Regulation; Vasodilator Agents

2007