Page last updated: 2024-09-03

n,n-dimethylarginine and Cardiovascular Diseases

n,n-dimethylarginine has been researched along with Cardiovascular Diseases in 279 studies

Research

Studies (279)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's112 (40.14)29.6817
2010's152 (54.48)24.3611
2020's15 (5.38)2.80

Authors

AuthorsStudies
Bonnitcha, P; Fitzpatrick, M; Ireland, A; Koay, YC; Nguyen, VL; O'Sullivan, J; Sullivan, D1
Chamienia, A; Dębska-Ślizień, A; Malgorzewicz, S; Puchalska-Reglińska, E; Wołoszyk-Chojecka, P1
Andraweera, PH; Arstall, MA; Kosmider, L; Lassi, ZS; Tiong, P1
Anderson, AH; Bhat, Z; Brown, J; Brunengraber, H; Charleston, J; Chen, J; Feldman, HI; He, J; Hostetter, TH; Hsu, CY; Ix, JH; Kimmel, PL; Mehta, R; Rao, P; Sapa, H; Schelling, JR; Schrauben, SJ; Seegmiller, JC; Shafi, T; Shlipak, MG; Townsend, R; Vasan, RS; Xie, D; Zhang, X1
Al-Abdulla, N; Bakhsh, A; Mannocci, F; Moyes, D; Niazi, SA; Proctor, G1
Bednarz-Misa, I; Bronowicka-Szydełko, A; Fleszar, MG; Gacka, M; Gamian, A; Kędzior, K; Krzystek-Korpacka, M; Masłowski, L; Wiśniewski, J; Witkiewicz, W1
Bode-Böger, SM; Jarzebska, N; Mangoni, AA; Martens-Lobenhoffer, J; Rodionov, RN1
Hu, W; Liu, T; Ma, Q; Wang, W; Zhang, J1
Derkacz, A; Gać, P; Gocławska, K; Jurdziak, M; Mazur, G; Poręba, M; Poręba, R; Szuba, A; Trzmielewska, E1
Doroszko, A; Gajecki, D; Gawrys, J; Szahidewicz-Krupska, E1
Ashokachakkaravarthy, K; Mohan Raj, PS; Parameswaran, S; Priyadarshini, G; Priyadarssini, M; Rajappa, M; Revathy, G; Satheesh, S1
Ochoa-Martínez, ÁC; Orta-García, ST; Pérez-Maldonado, IN; Varela-Silva, JA1
Du, Q; Gao, J; Jin, Y; Lu, R; Yan, Y; Yu, C; Zou, Y1
Dragičević, M; Košuta, I; Kruezi, E; Lovrenčić, MV; Mrzljak, A1
Bakker, SJL; Bollenbach, A; Post, A; Tsikas, D1
Charkiewicz, AE; Garley, M; Jabłońska, E; Maślach, D; Nowak, K; Omeljaniuk, WJ; Ratajczak-Wrona, W1
Dai, Z; Fan, Y; Xiang, S; Zhang, H1
Enko, D; März, W; Meinitzer, A; Pilz, S; Tomaschitz, A; Zelzer, S1
Arós, F; Clish, CB; Corella, D; Estruch, R; Fitó, M; Gómez-Gracia, E; Guasch-Ferré, M; Hruby, A; Hu, FB; Lapetra, J; Liang, L; Martínez-González, MA; Romaguera, D; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Serra-Majem, L; Toledo, E; Wang, DD; Yu, E1
Berge, RK; Gaardbo, JC; Gerstoft, J; Hove-Skovsgaard, M; Kolte, L; Nielsen, SD; Seljeflot, I; Svardal, A; Trøseid, M; Ullum, H; Winding, K1
Arya, S; Connelly, PW; Hanley, AJ; Retnakaran, R; Sermer, M; Ye, C; Zinman, B1
Hsu, CN; Tain, YL1
Alshahawey, M; Elsaid, TW; Sabri, NA; Shahin, SM1
Singh, SA; Srinivasan, K; Venkatesh, R1
Elliot, DJ; Hulin, JA; Lewis, BC; Mangoni, AA; McEvoy, M; Tommasi, S1
Choi, HR; Jeon, DH; Kim, HC; Lee, SW; Yeom, H; Youm, Y1
Javn, SB; Loganathan, S; Mala, K; Ramachandran, S; Sundari, M; Thomas, S1
Almendarez-Reyna, CI; Ochoa-Martínez, ÁC; Orta-García, ST; Pérez-Maldonado, IN; Ruíz-Vera, T1
Atzler, D; Böger, RH; Huisman, HW; Kruger, R; Malan, L; Malan, NT; Mels, CMC; Schutte, AE; Schwedhelm, E; Smith, W; van Rooyen, JM1
Chen, XP; Hu, XL; Li, MP; Song, PY; Tang, J1
Chang, J; Chen, JY; Hong, FF; Wang, XF; Yang, MW; Yang, SL; Ye, ZX; Zhong, HH1
Bode-Böger, SM; Emrich, IE; Fliser, D; Heine, GH; Martens-Lobenhoffer, J; Wagenpfeil, S; Zawada, AM1
Cardona-Lozano, ED; Carrizales-Yáñez, L; Ochoa-Martínez, ÁC; Pérez-Maldonado, IN1
Feng, S; Li, H; Lu, X; Wang, F; Wang, S; Xiong, R1
Aydogdu, A; Azal, O; Basaran, Y; Demir, O; Demirci, I; Dinc, M; Haymana, C; Meric, C; Sonmez, A; Torun, D; Yesildal, F1
Batista, MC; Mayer, S; Quinto, BMR; Triches, CB; Zanella, MT1
Aukrust, P; Gaardbo, JC; Gelpi, M; Gerstoft, J; Hoel, H; Holm, K; Hov, JR; Hove-Skovsgaard, M; Kummen, M; Nielsen, SD; Nwosu, F; Rudi, K; Seljeflot, I; Trøseid, M; Ueland, PM; Ullum, H; Valeur, J1
Chandrasekharan, UM; Elaine Husni, M; Hazen, SL; Wang, S; Wang, Z; Wilson Tang, WH; Wu, Y1
Briggs, WTE; Castro, C; FitzGerald, GA; Griffin, JL; Karlson, EW; Lahens, NF; Li, X; Malik, D; Meng, H; Rhoades, SD; Ricciotti, E; Sparks, JA; Tang, SY; Weljie, AM; West, JA1
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N1
Kulwas, A; Rość, D; Wieczór, AM; Wieczór, R1
Gouya, G; Litschauer, B; Ohrenberger, G; Sheikh Rezaei, S; Weisshaar, S; Wolzt, M1
Almendarez-Reyna, CI; Carrizales-Yáñez, L; Ochoa-Martínez, ÁC; Pérez-Maldonado, IN; Ruiz-Vera, T; Zarazúa, S1
Aleksandrowicz-Wrona, E; Dębska-Ślizień, A; Heleniak, Z; Lichodziejewska-Niemierko, M; Małgorzewicz, S; Rutkowski, R1
Fujisawa, Y; Gohda, T; Horikoshi, S; Kobayashi, T; Nishiyama, A; Shiota, S; Sugaya, T; Suzuki, Y; Takahashi, K; Ueda, S1
Fayh, APT; Krause, M; Rocha, IMGD; Rodrigues-Krause, J; Umpierre, D1
Fromm, MF; König, J; Maas, R; Taghikhani, E1
Bakker, SJL; Bollenbach, A; de Borst, MH; Frenay, AR; Kayacelebi, AA; Minović, I; Navis, G; Said, MY; Tsikas, D; van den Berg, E; van Goor, H; van Londen, M1
Dimitroulas, T; Kitas, GD1
Baamonde-Laborda, E; Gonzalez-Cabrera, F; Oliva-Damaso, E; Oliva-Damaso, N; Payan, J; Rodriguez-Esparragon, F; Rodriguez-Perez, JC; Santana-Estupiñan, R1
Auge, D; Chafai, A; Fromm, MF; Gessner, A; Maas, R; Mieth, M; Müller, F1
Linz, TH; Lunte, SM1
Bitla, AR; Reddy, VS; Sachan, A; Srinivas Rao, PV; Suchitra, MM; Suresh, V; Tejovathi, B1
Bouras, G; Deftereos, S1
Bouras, G; Chatzis, G; Cleman, MW; Deftereos, S; Giannopoulos, G; Stefanadis, C; Tousoulis, D; Tsounis, D1
Bandinelli, S; D'Arrigo, G; Dattolo, P; Ferrucci, L; Maas, R; Michelassi, S; Mieth, M; Pizzarelli, F; Tripepi, G; Zoccali, C1
Bogdanović, D; Cvetković, TP; Ignjatović, AM; Milošević, ZG; Pavlović, DD; Pavlović, RM; Stojanović, IR; Đorđević, VB; Đorđević, VM1
Arefin, S; Carrero, JJ; Hammarqvist, F; Kublickiene, K; Näslund, E; Nordfors, L; Qureshi, AR; Rydén, M; Stenvinkel, P; Witasp, A1
Cooke, JP; Erlanson, DA; Ghebremariam, YT; Lee, JC; Leiper, J; LePendu, P; Shah, NH; Slaviero, A1
Ajisaka, R; Eto, M; Kumagai, H; Maeda, S; Miyaki, A; So, R; Tanaka, K1
Chang, SL; Chao, TF; Chen, SA; Hsieh, MH; Hu, YF; Lin, YJ; Lo, LW; Lu, TM; Tsao, HM; Tuan, TC1
Boeger, RH; Hamer, M; Lambert, GW; Malan, L; Malan, NT; Reimann, M; Schlaich, MP; Ziemssen, T1
Anderssohn, M; Atzler, D; Ayers, CR; Böger, RH; de Lemos, JA; Gore, MO; Grant, PJ; Khera, A; Lüneburg, N; McGuire, DK; Schwedhelm, E1
Hudson, CL; Ipp, H; Zemlin, AE1
Ajjan, R; Anderssohn, M; Böger, RH; Grant, PJ; Lüneburg, N; McLachlan, S; Price, JF; Robertson, C; Schwedhelm, E; Strachan, MW; Williamson, RM1
Bramlage, C; Konstantinides, S; Koziolek, MJ; Mueller, GA; Puls, M; Strauchmann, J; Wallbach, M1
Chiarelli, F; Chiavaroli, V; de Giorgis, T; Diesse, L; Giannini, C; Marcovecchio, ML; Mohn, A1
Dimitroulas, T; Kitas, GD; Sandoo, A; Smith, JP1
Abd El Dayem, SM; Battah, AA; El Bohy, Ael M; El-Shehaby, A1
Baranyi, A; Kapfhammer, HP; Meinitzer, A; Putz-Bankuti, C; Rothenhäusler, HB; Stauber, R1
Ahmadi, Y; Badalzadeh, R; Faghfoori, Z; Ghavimi, H; Jabbarpour, M; Karami, H; Majidinia, M; Samadi, N; Shafiei-Irannejad, V; Yousefi, B1
Bode-Böger, SM; Fliser, D; Kielstein, JT; Schepers, E; Speer, T1
Atzler, D; Böger, RH; Dörr, M; Friedrich, N; Kroemer, HK; Nauck, M; Schwedhelm, E; Völker, U; Völzke, H; Wallaschofski, H1
Beckmann, B; Gutzki, FM; Jordan, J; Kayacelebi, AA; Tsikas, D1
Atzler, D; Böger, RH; Friedrich, N; Ittermann, T; Nauck, M; Schwedhelm, E1
Aukrust, P; Consoli, A; Davì, G; Di Fulvio, P; Formoso, G; Lattanzio, S; Liani, R; Santilli, F; Ueland, T; Vazzana, N1
Chan, WP; Chirkov, YY; Horowitz, JD; Ngo, DT; Sverdlov, AL1
Doerfer, J; Grulich-Henn, J; Grünert, SC; Holder, M; Krebs, A; Lichte, K; Schmidt-Trucksäss, A; Schwab, KO; Stier, B; Winkler, K; Wöhrl, J1
Dimitroulas, T; Douglas, KM; Hodson, J; Kitas, GD; Sandoo, A; Smith, JP1
Bilge, AK; Caliskan, Y; Deniz, G; Ozkok, A; Sariyar, M; Yildiz, A; Yilmaz, A; Yilmaz, BA1
Gerstoft, J; Kvale, D; Manner, IW; Nielsen, SD; Os, I; Pedersen, KK; Seljeflot, I; Trøseid, M1
Alpoim, PN; Dusse, LM; Mota, AP; Rios, DR; Sousa, LP1
Ahmetaj-Shala, B; Al'Yamani, M; Armstrong, PC; Kirkby, NS; Knowles, R; Leiper, J; Mackenzie, L; Mazi, S; Mitchell, JA; Nüsing, RM; Tomlinson, JA; Tucker, AT; Wang, Z; Warner, TD1
Cefle, A; Kir, HM; Sahin, T; Unlu, BÖ; Yilmazer, B1
Eichelberger, B; Gremmel, T; Kopp, CW; Koppensteiner, R; Panzer, S; Perkmann, T; Seidinger, D; Steiner, S1
Cetinkaya, H; Eyileten, T; Gok, M; Haymana, C; Karaman, M; Oguz, Y; Rizzo, M; Saglam, M; Sonmez, A; Toth, PP; Unal, HU; Vural, A; Yilmaz, MI1
Kaneko, K; Kuroyanagi, Y; Takaya, J; Tanabe, Y1
Akilli, H; Alibasic, H; Aribas, A; Gunduz, M; Kayrak, M; Taner, A; Tekinalp, M; Unlu, A; Yildirim, S1
Chowdhury, R; Chowdhury, S; Di Angelantonio, E; Freitag, DF; Gobin, R; Laukkanen, JA; Mayr, M; Willeit, P1
İn, E; Kaman, D; Özdemir, C; Sökücü, SN1
Georgakis, MK; Latsios, G; Oikonomou, E; Papageorgiou, N; Papaioannou, S; Siasos, G; Tousoulis, D; Zaromitidou, M1
Atzler, D; Baum, C; Blankenberg, S; Böger, RH; Gori, T; Johannsen, SS; Lackner, KJ; Münzel, T; Ojeda, FM; Schnabel, RB; Schwedhelm, E; Sinning, CR; Wild, PS; Zeller, T1
Banderali, G; Cefalo, G; Giovannini, M; Lassandro, C; Moretti, F; Radaelli, G; Salvatici, E; Verduci, E1
Aly, H; El Melegy, S; El Shikh, T; El-Batch, M; Rowisha, M1
Antonelli-Incalzi, R; Battistoni, F; Chiurco, D; Costanzo, L; Pedone, C; Santangelo, S1
Afsar, B; Covic, A; Eyileten, T; Gezer, M; Johnson, RJ; Kanbay, M; Karaman, M; Oguz, Y; Ortiz, A; Saglam, M; Siriopol, D; Unal, HU; Verim, S; Vural, A; Yilmaz, MI1
Chrysis, D; Efthymiadou, A; Kritikou, D; Mermigka, A; Spiliotis, BE1
Guo, BC; Hsu, CP; Lee, TS; Lin, SJ; Lu, TM; Shyue, SK; Zhao, JF1
Chybicka, A; Doroszko, A; Jakubowski, M; Mazur, G; Niedzielska, E; Porwolik, J; Szahidewicz-Krupska, E; Szuba, A; Turek-Jakubowska, A1
Boaz, M; Ganz, T; Gilad, S; Limor, R; Stern, N; Wainstein, J1
Chen, XL; Gao, XR; Lao, MC; Liu, LJ; Lu, GH; Luo, CF; Zhai, YS1
Bode-Böger, SM; Bornstein, SR; Brilloff, S; Brocker, C; Burdin, DV; Demyanov, AV; Gonzalez, F; Jarzebska, N; Kolobov, AA; Maas, R; Martens-Lobenhoffer, J; Mieth, M; Rodionov, RN; Samusik, N; Soshnev, AA; Weiss, N1
Banerjee, T; Coresh, J; Hai, X; Hostetter, TH; Hwang, S; Melamed, ML; Meyer, TW; Powe, NR; Shafi, T1
Abe, Y; Arai, Y; Hirata, T; Ohkuma, K; Takayama, M; Takebayashi, T1
Gongora, E; Nair, N1
Abdel Hamid, SG; El-Mesallamy, HO; Gad, MZ1
Alfthan, G; Hutri-Kähönen, N; Jula, A; Juonala, M; Kähönen, M; Laaksonen, R; Lehtimäki, T; Päivä, H; Raitakari, OT; Viikari, J1
Zsuga, J1
Alchanatis, M; Dimitriadis, K; Kallikazaros, I; Manolis, A; Stefanadis, C; Thomopoulos, C; Tousoulis, D; Tsiachris, D; Tsioufis, C1
Aso, Y1
Kaida, Y; Matsumoto, Y; Okuda, S; Ueda, S; Yamagishi, S1
Krzyzanowska, K; Mittermayer, F; Wolzt, M1
Getino, MA; Jarque, A; Lozano, L; Mora-Fernández, C; Navarro, JF; Sánchez, R1
Agustí, AG; Alonso, A; Ayllón, O; Barceló, A; de la Peña, M; González, C; Pérez, G; Piérola, J; Vega-Agapito, MV1
Yilmaz, MB; Yontar, OC1
Krzyzanowska, K; Mittermayer, F; Schernthaner, G; Wolzt, M2
Bode-Böger, SM; Ertl, T; Lakatos, O; Martens-Lobenhoffer, J; Sulyok, E; Vida, G1
Celik, T; Iyisoy, A; Jata, B; Yuksel, C1
Egger, G; Holt, DW; Kiechl, S; Lee, T; Mayr, M; Santer, P; Thompson, G; Tsimikas, S; Willeit, J; Xu, Q1
Mallamaci, F; Zoccali, C1
Benjamin, EJ; Benndorf, RA; Böger, RH; Maas, R; Schulze, F; Schwedhelm, E; Sullivan, LM; Vasan, RS; Wang, TJ; Xanthakis, V1
Mangoni, AA; Wadham, C1
Bianchi, M; De Gennaro Colonna, V; Ferrario, P; Morelli, F; Pascale, V; Pascale, W; Tomasoni, L; Turiel, M1
Ayer, JG; Celermajer, DS; Harmer, JA; Marks, GB; Nakhla, S; Ng, MK; Raitakari, OT; Xuan, W1
Benndorf, RA; Böger, RH; Maas, R; Riederer, U; Schulze, F; Schwedhelm, E; Sullivan, LM; Vasan, RS; Xanthakis, V1
Brennan, DM; Cho, L; Hazen, SL; Tang, WH; Wang, Z1
Böger, RH; Maas, R; Schulze, F; Schwedhelm, E2
Fuchs, D; Kurz, K; Sarcletti, M; Teerlink, T; Weiss, G; Zangerle, R1
Chirkov, YY; Horowitz, JD; McNeil, JJ; Ngo, DT; Nightingale, AK; Sverdlov, AL; Willoughby, SR1
Cardounel, AJ; Karuppiah, K; Pope, AJ1
Luo, Z; Palm, F; Teerlink, T; Wilcox, CS1
Mangoni, AA1
Abedini, S; Fellstrøm, B; Holdaas, H; Holme, I; Jardine, A; März, W; Meinitzer, A; Weihrauch, G1
Böger, RH7
Fair, JM; Fortmann, SP; Go, AS; Hlatky, MA; Iribarren, C; Sydow, K; Tsao, PS; Varady, A1
Blackwell, S1
Bode-Böger, SM; David, S; Fliser, D; Haller, H; Kielstein, JT; Kliem, V; Kümpers, P; Lukasz, A; Martens-Lobenhoffer, J1
Förstermann, U1
Arend, M; Atzler, D; Böger, RH; Cardounel, AJ; Cordasic, N; Heusinger-Ribeiro, J; Hilgers, KF; Jacobi, J; Maas, R; Pope, AJ; Schwedhelm, E; Strobel, J1
Evans, A; Gey, KF; Gilchrist, SE; McKinley, MC; O'Doherty, MG; Skidmore, PM; Woodside, JV; Yarnell, JW; Young, IS1
Dohi, Y; Ito, A; Itoh, T; Kajikuri, J; Koyama, K; Kumagai, H; Nakamura, H; Nishio, T; Ohte, N; Sano, A; Yamamoto, J1
Ayhan, SS; Bacaksiz, A; Kayrak, M; Taner, A; Ulgen, MS; Unlü, A; Vatankulu, MA; Yazici, M1
Azqueta, M; Cases, A; Coll, E; Collado, S; Cruzado, JM; de la Torre, B; Deulofeu, R; Guerrero, L; Nicolau, C; Pons, M; Vera, M1
Artusi, C; Boffa, GM; Ivanova, M; Plebani, M; Zaninotto, M1
Berta, A; Biri, B; Bodnár, N; Gesztelyi, R; Kéki, S; Kemény-Beke, Á; Kerekes, G; Szántó, S; Szekanecz, Z; Szodoray, P; Zsuga, J; Zsuga, M1
Aleksandrowicz-Wrona, E; Lichodziejewska-Niemierko, M; Małgorzewicz, S; Rutkowski, B; Świetlik, D; Łysiak-Szydłowska, W1
Alfthan, G; Hutri-Kähönen, N; Juonala, M; Kähönen, M; Laaksonen, R; Laitinen, T; Lehtimäki, T; Päivä, H; Raitakari, OT; Taittonen, L; Viikari, J1
Engin-Üstün, Y; Kafkasli, A; Kali, Z; Karabulut, AB; Meydanli, M; Turan, F; Türkçüoğlu, I1
Ayhan, S; Demir, K; Erdem, S; Karabag, T; Kaya, A; Kaya, C; Koc, F; Tokac, M; Unlu, A; Vatankulu, MA1
Boehm, BO; Drechsler, C; Kielstein, JT; März, W; Meinitzer, A; Pilz, S; Ritz, E; Winkelmann, BR1
Aydin, M; Batioglu, S; Erdogan, G; Kilic, S; Yilmaz, N; Zulfikaroglu, E1
Kanazawa, I; Nabika, T; Notsu, Y; Sugimoto, T; Yamaguchi, T; Yano, S1
Atzler, D; Benndorf, RA; Böger, RH; Darius, H; Diehm, C; Endres, HG; Lüneburg, N; Maas, R; Schwedhelm, E; Thiem, U; von Stritzky, B1
Ahmetaj, B; Arrigoni, F; Leiper, J1
Dalton, RN; Dunger, DB; Marcovecchio, ML; Turner, C; Widmer, B1
Chung, MY; Hsu, CP; Lin, MW; Lin, SJ; Lu, TM2
Jin, LJ; Li, X; Tse, HF1
Jackson, G; Wierzbicki, AS1
Aggelis, A; Alexopoulos, N; Ioakeimidis, N; Rokkas, K; Samentzas, A; Stefanadis, C; Terentes-Printzios, D; Vlachopoulos, C1
Huang, LT; Tain, YL1
Gu, LQ; Li, FY; Liu, JM; Liu, Y; Ning, G; Zhang, MJ; Zhao, L; Zhao, YJ; Zhu, W1
Drexel, V; Emslander, I; Halle, M; Hanssen, H; Hertel, G; Kotliar, KE; Lorang, D; Nickel, T; Pressler, A; Schmidt-Trucksäss, A; Schuster, T; Sisic, Z; Weis, M1
Aasarød, K; Åsberg, A; Bigonah, A; Hatlen, G; Hov, GG; Sagen, E1
Atzler, D; Bache, RJ; Böger, RH; Chen, Y; Fassett, J; Guo, H; Hu, X; Lu, Z; Schwedhelm, E; Xu, X; Zhang, P1
Cameron, JD; Moran, LJ; Strauss, BJ; Teede, HJ1
Boger, R; Maas, R; Malatino, L; Mallamaci, F; Mattace Raso, F; Rapisarda, F; Seck, MS; Sijbrands, E; Tripepi, G; Witteman, J; Zoccali, C1
Cooke, JP; Ghebremariam, YT1
Bogner, M; Elmadfa, I; Fabian, E1
Agusti, AG; Alonso, A; Ayllón, O; Barbè, F; Barceló, A; de la Peña, M; Esquinas, C; Piérola, J; Sanchez-de la Torre, M1
Oikonomou, E; Papageorgiou, N; Papavassiliou, AG; Siasos, G; Stefanadis, C; Stougianos, P; Tousoulis, D1
Bicchieri, L; Di Gennaro, C; Manfredi, G; Montanari, A; Palombi, F; Pellegrino, A; Pinelli, S; Saccani-Jotti, G; Sansoni, P; Venturi, N1
Atzler, D; Baldus, S; Blankenberg, S; Böger, RH; D'Alecy, LG; Ehmke, H; Gadegbeku, CA; Hellwinkel, O; Kielstein, JT; Klinke, A; Kubala, L; Lau, D; Lund, N; Maas, R; Meinertz, T; Pekarova, M; Schmidt-Haupt, R; Schwedhelm, E; Slocum, JL; Sydow, K; Tsikas, D; von Leitner, EC; Willems, S1
Anderssohn, M; Böger, RH; Fourie, CM; Glyn, MC; Huisman, HW; Lüneburg, N; Malan, L; Malan, NT; Mels, CM; Schutte, AE; Schutte, R; Smith, W; Van Rooyen, JM1
Wilcox, CS1
Chen, J; Chen, R; Goligorsky, MS; Lu, CY; Moskowitz-Kassai, E; Sanduski, K; Špes, A; Turk, B; Xavier, S1
Fijorek, K; Goralczyk, T; Tisonczyk, J; Undas, A1
Alsagaff, MY; Aminuddin, M; Thaha, M; Tomino, Y; Yogiantoro, M; Yogiarto, RM1
Caplin, B; Leiper, J1
Kimura, K1
Brinkworth, GD; Buckley, JD; Clifton, PM; Noakes, M; Norman, RJ; Thomson, RL1
Derbent, A; Gumus, II; Karakurt, F; Kargili, A; Kasapoglu, B; Kaygusuz, I; Uysal, S1
Wierzbicki, AS1
Auge, D; Endress, B; Fromm, MF; König, J; Maas, R; Mieth, M; Strobel, J1
Balwierz, W; Ćwiklińska, M; Grodzicki, TK; Gryglewska, B; Kwater, A; Strach, M; Sulicka, J; Surdacki, A1
Clifton, PM; Moran, LJ; Noakes, M; Norman, RJ; Wittert, GA1
Chen, XM; Hu, CP; Jiang, JL; Li, YJ1
Ahmed, IK; Ali, SR; Elmageed, AM; Saleh, BI1
Aldámiz-Echevarría, L; Andrade, F1
Angelidi, A; Dimitriadis, G; Foussas, S; Gritzapis, A; Matsagos, S; Melidonis, A; Panoutsopoulos, GI; Protopsaltis, I; Raptis, S; Sergentanis, TΝ; Tzirogiannis, K1
Aydin, Z; Gurdal, A; Gursu, M; Karadag, S; Kazancioglu, R; Koldas, M; Kumbasar, B; Ozturk, S; Uzun, S; Yegen, M1
Dimitroulas, T; Kitas, GD; Sandoo, A1
Gao, Y; Vanhoutte, PM1
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A1
Fujiwara, N; Nakamura, M; Okumura, K; Osanai, T; Osawa, H; Saitoh, M; Sasaki, S; Tomita, H; Yamabe, H1
Zoccali, C3
Hansson, L; Hedner, T; Himmelmann, A1
Chan, JC; Chan, NN1
de Jong, S; Neele, SJ; Netelenbos, JC; Stehouwer, CD; Teerlink, T1
Bode-Böger, SM; Fliser, D; Haller, H; Kielstein, JT1
Bonfigli, AR; Coppa, G; Gambini, A; Marra, M; Testa, I; Testa, R1
Kenemans, P; Post, MS; Stehouwer, CD; Teerlink, T; van der Mooren, MJ; Verhoeven, MO1
Magota, K; Murakami, S; Nakamura, M; Okumura, K; Osanai, T; Osawa, H; Saitoh, M; Sasaki, S; Tomita, H; Yamabe, H1
Böger, RH; Cooke, JP; Vallance, P1
Böger, RH; Zoccali, C1
Münzel, T; Sydow, K1
Cooke, JP3
Dayal, S; Lentz, SR; Rodionov, RN1
Mallamaci, F; Tripepi, G; Zoccali, C1
Cooke, JP; Gao, SZ; Kledal, TN; Lin, KY; Mocarski, ES; Panchal, SN; Valantine, HA; Weis, M1
Leiper, J; Vallance, P1
Laaksonen, R; Valkonen, VP1
Yoshizumi, M1
Böger, RH; Ron, ES1
Brodsky, SV; Chen, J; Goligorsky, MS; Li, H; O'Riordan, E; Smirnova, I1
Cutrupi, S; Malatino, LS; Mallamaci, F; Tripepi, G; Zoccali, C1
Jackson, G; Lambert-Hammill, M; Lumb, PJ; Lyttle, K; Solomon, H; Wierzbicki, AS1
Enia, G; Mallamaci, F; Panuccio, V; Tripepi, G; Zoccali, C1
Akgul, EO; Beyhan, Z; Bilgi, C; Cakir, E; Erbil, MK; Erturk, K; Ozcan, O; Yaman, H1
Bickel, C; Blankenberg, S; Cambien, F; Espinola-Klein, C; Jachmann, N; Lackner, KJ; Lubos, E; Münzel, T; Peetz, D; Post, F; Rupprecht, HJ; Schnabel, R; Tiret, L1
Bultink, IE; Dijkmans, BA; Heijst, JA; Teerlink, T; Voskuyl, AE1
Kielstein, JT; Zoccali, C2
Boeger, R; Fatuzzo, P; Maas, R; Malatino, L; Mallamaci, F; Spoto, B; Testa, A; Tripepi, G; Zoccali, C1
Böger, RH; Freese, R; Maas, R; Schulze, F; Schwedhelm, E; Silberhorn, E1
Anthony, S; Hubank, M; Leiper, JM; Smith, CL; Vallance, P1
Teerlink, T1
Bauersachs, J; Thum, T1
Markov, KhM1
Acikel, C; Aydin, A; Caglar, K; Cakir, E; Erbil, K; Eyileten, T; Genctoy, G; Ozcan, O; Ozgurtas, T; Saglam, M; Sonmez, A; Tasar, M; Vural, A; Yilmaz, MI; Zoccali, C1
Grdić, M; Huber, K; Maurer, G; Niessner, A; Penka, M; Richter, B; Simeon-Rudolf, V; Steiner, S; Strasser, B; Wojta, J; Ziegler, S; Zorn, G1
Dayal, S; Lentz, SR1
Cooke, JP; Mondon, CE; Sydow, K1
Laaksonen, R; Tuomainen, TP; Valkonen, VP1
Maas, R1
Cambou, JP; Cottin, Y; Danchin, N; Empana, JP; Ferrières, J; Jouven, X; Paillard, F; Thomas, D; Valensi, P; Zeller, M1
Brouwer, CB; Rauwerda, JA; Smulders, YM; Spoelstra-de Man, AM; Stehouwer, CD; Teerlink, T1
Cibulka, R; Racek, J; Rajdl, D; Siroká, R1
Branca, F; Bugel, S; Dahlman-Wright, K; Dierkes, J; Ferrari, M; Hall, WL; Hallund, J; Huebner, U; Koebnick, C; Nilsson, M; Reimann, M; Vafeiadou, K; Williams, CM1
Goss, M; Kopieczna-Grzebieniak, E1
Barth, SW; Bub, A; Hahn, A; Hülsmann, O; Kressel, G; Kühn-Velten, WN; Lichtinghagen, R; Schmitt, B; Stichtenoth, DO; Ströhle, A; Wolters, M1
Hirata, Y1
Amighi, J; Exner, M; Krzyzanowska, K; Minar, E; Mittermayer, F; Mlekusch, W; Müller, M; Sabeti, S; Schillinger, M; Wolzt, M1
Baylis, C1
Hishida, A; Ikegaya, N; Kato, A; Kumagai, H; Maruyama, Y; Sakurai, M; Takita, T; Uno, S1
Boehm, BO; Halwachs-Baumann, G; März, W; Meinitzer, A; Seelhorst, U; Wellnitz, B; Winkelmann, BR1
Cooke, JP; Kielstein, JT1
Podgórski, M; Szuba, A1
Ardigo, D; Franzini, L; Pachinger, O; Piatti, PM; Reaven, GM; Stüehlinger, M; Valtueña, S; Zavaroni, I1
Fliser, D; Kielstein, JT1
Böger, RH; Dentz, L; Haddad, M; Hiltmeyer, N; Klöss, T; Kuss, O; Maas, R; Schwedhelm, E; Standl, T; Thoms, W1
Smith, CL1
Fukami, K; Matsumoto, Y; Okuda, S; Ueda, S; Yamagishi, SI1
Lipman, ML; Mann, JF; Schiffrin, EL1
Durante, W; Johnson, FK; Johnson, RA1
Alfthan, G; Juonala, M; Kähönen, M; Laitinen, T; Marniemi, J; Raitakari, OT; Taittonen, L; Viikari, JS1
Bekpinar, S; Can, A; Cetinalp-Demircan, P; Orhan, Y; Unlucerci, Y1
Blankenberg, S; Schnabel, R1
Baysal, E; Maden, O; Ozeke, O; Sasmaz, A; Selcuk, H; Selcuk, MT; Temizhan, A; Ulupinar, H1
Luo, Z; Onozato, ML; Palm, F; Wilcox, CS1
Arning, E; Bottiglieri, T; Cooke, JP; Dayoub, H; Faraci, FM; Lentz, SR; Lynch, C; Rodionov, RN1
Andreotti, F; Coluzzi, G; Marzo, F; Santucci, E1
Axelsson, J; Carrero, JJ; Heimbürger, O; Lindholm, B; Massy, Z; Stenvinkel, P1
Boeger, RH; Deussen, A; Henle, T; Pexa, A; Schwedhelm, E1
Lentz, SR; Rodionov, RN1
Abbasi, F; Chu, JW; Cooke, JP; Lamendola, C; McLaughlin, TL; Reaven, GM; Stühlinger, MC; Tsao, PS1
Nash, DT1

Reviews

88 review(s) available for n,n-dimethylarginine and Cardiovascular Diseases

ArticleYear
Asymmetric dimethylarginine and gestational diabetes mellitus: a systematic review and meta-analysis.
    Endocrine, 2023, Volume: 80, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Humans; Postpartum Period; Pregnancy

2023
The Second Life of Methylarginines as Cardiovascular Targets.
    International journal of molecular sciences, 2019, Sep-17, Volume: 20, Issue:18

    Topics: Amidohydrolases; Animals; Arginine; Biological Transport; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Disease Susceptibility; Energy Metabolism; Humans; Molecular Targeted Therapy

2019
Intraplatelet L-Arginine-Nitric Oxide Metabolic Pathway: From Discovery to Clinical Implications in Prevention and Treatment of Cardiovascular Disorders.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Amidohydrolases; Arginine; Blood Platelets; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Networks and Pathways; Nitric Oxide; Nitric Oxide Synthase; Risk Factors

2020
Asymmetric dimethylarginine level as biomarkers of cardiovascular or all-cause mortality in patients with chronic kidney disease: a meta-analysis.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2021, Volume: 26, Issue:7

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Cause of Death; Humans; Mortality; Renal Insufficiency, Chronic

2021
Interplay between Oxidative Stress and Nutrient Sensing Signaling in the Developmental Origins of Cardiovascular Disease.
    International journal of molecular sciences, 2017, Apr-15, Volume: 18, Issue:4

    Topics: Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Energy Metabolism; Humans; Nitric Oxide; Nutritional Physiological Phenomena; Oxidative Stress; Reactive Oxygen Species; Signal Transduction

2017
Polycystic ovarian syndrome-associated cardiovascular complications: An overview of the association between the biochemical markers and potential strategies for their prevention and elimination.
    Diabetes & metabolic syndrome, 2017, Volume: 11 Suppl 2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Female; Glycation End Products, Advanced; Homocysteine; Humans; Oxidative Stress; Polycystic Ovary Syndrome; Receptor for Advanced Glycation End Products; von Willebrand Factor

2017
AGXT2: An unnegligible aminotransferase in cardiovascular and urinary systems.
    Journal of molecular and cellular cardiology, 2017, Volume: 113

    Topics: Animals; Arginine; Cardiovascular Diseases; Cardiovascular System; Humans; Kidney Diseases; Transaminases

2017
Nitric oxide bioavailability dysfunction involves in atherosclerosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Animals; Arginine; Atherosclerosis; Biological Availability; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide; Obesity; Oxidative Stress; Smoking; Vasodilation

2018
Association of Circulating Levels of ADMA with Carotid Intima-Media Thickness in Patients with CKD: a Systematic Review and Meta-Analysis.
    Kidney & blood pressure research, 2018, Volume: 43, Issue:1

    Topics: Arginine; Atherosclerosis; Cardiovascular Diseases; Carotid Intima-Media Thickness; Humans; Renal Insufficiency, Chronic

2018
Asymmetric dimethylarginine and angiogenesis: biological significance.
    International angiology : a journal of the International Union of Angiology, 2018, Volume: 37, Issue:6

    Topics: Animals; Arginine; Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Humans; Neovascularization, Pathologic; Neovascularization, Physiologic; Plaque, Atherosclerotic; Signal Transduction; Up-Regulation

2018
Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Nutrients, 2018, Dec-20, Volume: 11, Issue:1

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Dietary Supplements; Endothelium, Vascular; Female; Humans; Hyperemia; Male; Middle Aged; Nitrates; Nitrites; Obesity; Treatment Outcome

2018
Genetic regulation of dimethylarginines and endothelial dysfunction in rheumatoid arthritis.
    Amino acids, 2019, Volume: 51, Issue:7

    Topics: Arginine; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Humans; Inflammation; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Single Nucleotide; Transaminases

2019
Asymmetric (ADMA) and Symmetric (SDMA) Dimethylarginines in Chronic Kidney Disease: A Clinical Approach.
    International journal of molecular sciences, 2019, Jul-26, Volume: 20, Issue:15

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic

2019
Asymmetric Dimethylarginine (ADMA): a promising biomarker for cardiovascular disease?
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:2

    Topics: Aging; Amidohydrolases; Arginine; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Diabetes Complications; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Mass Spectrometry; Nitric Oxide; Oxidative Stress; Reference Values; Risk Factors; Smoking

2013
Is asymmetric dimethylarginine associated with being born small and large for gestational age?
    Antioxidants & redox signaling, 2014, May-20, Volume: 20, Issue:15

    Topics: Arginine; Biomarkers; Birth Weight; Cardiovascular Diseases; Female; Gestational Age; Humans; Metabolic Diseases; Pregnancy

2014
Dimethylarginines ADMA and SDMA: the real water-soluble small toxins?
    Seminars in nephrology, 2014, Volume: 34, Issue:2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Humans; Kidney Diseases; Water

2014
Asymmetric Dimethylarginine (ADMA) in cardiovascular and renal disease.
    Clinica chimica acta; international journal of clinical chemistry, 2015, Feb-02, Volume: 440

    Topics: Arginine; Cardiovascular Diseases; Humans; Kidney Diseases; Kidney Transplantation; Nitric Oxide; Nitric Oxide Synthase; Proteinuria

2015
Asymmetric dimethylarginine and cardiovascular risk: systematic review and meta-analysis of 22 prospective studies.
    Journal of the American Heart Association, 2015, May-28, Volume: 4, Issue:6

    Topics: Arginine; Cardiovascular Diseases; Humans; Odds Ratio; Prospective Studies; Stroke

2015
Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.
    Current medicinal chemistry, 2015, Volume: 22, Issue:24

    Topics: Alzheimer Disease; Animals; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypercholesterolemia; Neoplasms; Pre-Eclampsia; Pregnancy; Renal Insufficiency, Chronic

2015
Diet in children with phenylketonuria and risk of cardiovascular disease: A narrative overview.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2016, Volume: 26, Issue:3

    Topics: Adiponectin; Arginine; Blood Pressure; Cardiovascular Diseases; Child; Cholesterol, HDL; Cholesterol, LDL; Diet; Homocysteine; Humans; Oxidative Stress; Pediatric Obesity; Phenylalanine; Phenylketonurias; Risk Factors

2016
Oxidative Stress and Cardiovascular Aging: Interaction Between NRF-2 and ADMA.
    Current cardiology reviews, 2017, Volume: 13, Issue:3

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction

2017
Cardiovascular disease in patients with diabetic nephropathy.
    Current molecular medicine, 2008, Volume: 8, Issue:6

    Topics: Anemia; Arginine; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Diabetic Nephropathies; Enzyme Inhibitors; Glycation End Products, Advanced; Homocysteine; Humans; Prognosis; Risk Factors

2008
[Endothelial injury and CKD].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:9

    Topics: Animals; Arginine; Cardiovascular Diseases; Chronic Disease; Endothelium, Vascular; Humans; Kidney Diseases; Kidney Failure, Chronic; Nitric Oxide; Risk Factors

2008
[Asymmetric dimethylarginine (ADMA): A cardiovascular risk factor].
    Wiener klinische Wochenschrift, 2008, Volume: 120, Issue:15-16

    Topics: Adult; Arginine; Austria; Biomarkers; Cardiovascular Diseases; Humans; Male; Prevalence; Risk Assessment; Risk Factors

2008
[Novelties in the field of progression factors in chronic kidney disease].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2008, Volume: 28 Suppl 5

    Topics: Adult; Amidohydrolases; Animals; Arginine; Carbon; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Disease Progression; Female; Genetic Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infant, Low Birth Weight; Infant, Newborn; Kidney Diseases; Male; Oxides; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Uremia; Uric Acid

2008
ADMA, cardiovascular disease and diabetes.
    Diabetes research and clinical practice, 2008, Dec-15, Volume: 82 Suppl 2

    Topics: Arginine; Cardiovascular Diseases; Diabetes Mellitus; Humans; Models, Biological

2008
Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease.
    Expert opinion on drug metabolism & toxicology, 2009, Volume: 5, Issue:3

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Agents; Cardiovascular Diseases; Disease Progression; Drug Delivery Systems; Gene Expression Regulation, Enzymologic; Humans; Nitric Oxide

2009
Asymmetric dimethylarginine (ADMA): an endogenous inhibitor of nitric oxide synthase and a novel cardiovascular risk molecule.
    Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:4

    Topics: Animals; Arginine; Cardiovascular Diseases; Enzyme Inhibitors; Humans; Kidney; Nitric Oxide Synthase; Risk Factors

2009
Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality--an update on patient populations with a wide range of cardiovascular risk.
    Pharmacological research, 2009, Volume: 60, Issue:6

    Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Prospective Studies; Risk Factors

2009
Role of the PRMT-DDAH-ADMA axis in the regulation of endothelial nitric oxide production.
    Pharmacological research, 2009, Volume: 60, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Protein-Arginine N-Methyltransferases

2009
Cellular ADMA: regulation and action.
    Pharmacological research, 2009, Volume: 60, Issue:6

    Topics: Animals; Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide Synthase; Signal Transduction

2009
The emerging role of symmetric dimethylarginine in vascular disease.
    Advances in clinical chemistry, 2009, Volume: 48

    Topics: Arginine; Cardiovascular Diseases; Homeostasis; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Renal Insufficiency

2009
The biochemistry, measurement and current clinical significance of asymmetric dimethylarginine.
    Annals of clinical biochemistry, 2010, Volume: 47, Issue:Pt 1

    Topics: Amidohydrolases; Animals; Arginine; Biochemistry; Cardiovascular Diseases; Enzyme Inhibitors; Humans; Metabolic Clearance Rate; Models, Biological; Nitric Oxide Synthase; Oxidative Stress; Prognosis

2010
Nitric oxide and oxidative stress in vascular disease.
    Pflugers Archiv : European journal of physiology, 2010, Volume: 459, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Arginine; Aryldialkylphosphatase; Biopterins; Calcium; Cardiovascular Diseases; Catalase; Electron Transport; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mitochondria; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Protein Multimerization; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Factors; Superoxide Dismutase; Superoxides; Thioredoxins; Vascular Diseases; Xanthine Oxidase

2010
The biology and therapeutic potential of the DDAH/ADMA pathway.
    Current pharmaceutical design, 2010, Volume: 16, Issue:37

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Synthase

2010
Novel endothelial biomarkers: implications for periodontal disease and CVD.
    Journal of dental research, 2011, Volume: 90, Issue:9

    Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Cell-Derived Microparticles; Endothelial Cells; Endothelium, Vascular; Gingivitis; Humans; Nitric Oxide Synthase; Periodontitis; Stem Cells

2011
Asymmetric dimethylarginine: clinical applications in pediatric medicine.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2011, Volume: 110, Issue:2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Child, Preschool; Endothelium, Vascular; Enzyme Inhibitors; Humans; Infant; Nitric Oxide Synthase; Pediatrics; Reference Values; Risk Factors

2011
Asymmetric dimethylarginine and reactive oxygen species: unwelcome twin visitors to the cardiovascular and kidney disease tables.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:2

    Topics: Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Humans; Kidney Diseases; Rats; Reactive Oxygen Species; Risk Factors

2012
Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators, and regulators?
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Binding Sites; Binding, Competitive; Biomarkers; Cardiovascular Agents; Cardiovascular Diseases; Catalytic Domain; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

2012
[Methylarginies-induced endothelial dysfunction in chronic kidney disease].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2012, Volume: 132, Issue:4

    Topics: Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Renal Insufficiency, Chronic; Risk Factors

2012
New directions in cardiovascular risk assessment: the role of secondary risk stratification markers.
    International journal of clinical practice, 2012, Volume: 66, Issue:7

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adrenomedullin; Ankle Brachial Index; Arginine; Biomarkers; Blood Flow Velocity; C-Reactive Protein; Cardiovascular Diseases; Carotid Intima-Media Thickness; Early Diagnosis; Humans; Lipoprotein(a); Natriuretic Peptide, Brain; Peptide Fragments; Protein Precursors; Risk Assessment; Troponin; Vascular Calcification; Vasodilation

2012
Cardiovascular risk in autoimmune disorders: role of asymmetric dimethylarginine.
    European journal of pharmacology, 2012, Dec-05, Volume: 696, Issue:1-3

    Topics: Animals; Arginine; Autoimmune Diseases; Cardiovascular Diseases; Humans; Risk

2012
Asymmetric dimethylarginine, endothelial dysfunction and renal disease.
    International journal of molecular sciences, 2012, Volume: 13, Issue:9

    Topics: Adult; Amidohydrolases; Arginine; Biomarkers; Cardiovascular Diseases; Child; Disease Progression; Endothelial Cells; Endothelium, Vascular; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Nitric Oxide; Oxidative Stress; Risk Factors

2012
Asymmetric dimethylarginine as a surrogate marker of endothelial dysfunction and cardiovascular risk in patients with systemic rheumatic diseases.
    International journal of molecular sciences, 2012, Sep-26, Volume: 13, Issue:10

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Rheumatic Diseases; Risk Factors

2012
Beta blockers, nitric oxide, and cardiovascular disease.
    Current opinion in pharmacology, 2013, Volume: 13, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Arginine; Cardiovascular Diseases; Humans; Nitric Oxide; Vasodilation

2013
Asymmetric dimethylarginine (ADMA): a potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome?
    Diabetologia, 2002, Volume: 45, Issue:12

    Topics: Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Syndrome

2002
[Cardiovascular events in chronic advanced renal insufficiency. Current concepts].
    Recenti progressi in medicina, 2003, Volume: 94, Issue:3

    Topics: Anemia; Arginine; C-Reactive Protein; Cardiovascular Diseases; Humans; Hyperhomocysteinemia; Hyperlipidemias; Hypertension; Inflammation; Kidney Failure, Chronic; Nitric Oxide Synthase; Risk Factors; Sleep Apnea Syndromes; Smoking

2003
Asymmetric dimethylarginine: a cardiovascular risk factor in renal disease?
    Kidney international. Supplement, 2003, Issue:84

    Topics: Arginine; Cardiovascular Diseases; Humans; Kidney Diseases; Risk Factors

2003
The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor.
    Cardiovascular research, 2003, Oct-01, Volume: 59, Issue:4

    Topics: Amidohydrolases; Arginine; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide Synthase; Risk Factors

2003
ADMA: a novel risk factor that explains excess cardiovascular event rate in patients with end-stage renal disease.
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Kidney Failure, Chronic; Nitric Oxide Synthase; Risk Factors

2003
ADMA and oxidative stress.
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide Synthase; Oxidative Stress; Vasodilation

2003
NO and angiogenesis.
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Angiogenesis Inhibitors; Arginine; Cardiovascular Diseases; Cell Movement; Cell Survival; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide

2003
Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA.
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hyperhomocysteinemia; Risk Factors

2003
Novel cardiovascular risk factors in end-stage renal disease.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15 Suppl 1

    Topics: Arginine; Calcinosis; Cardiovascular Diseases; Humans; Hypertension; Inflammation; Kidney Failure, Chronic; Nitric Oxide Synthase; Oxidative Stress; Risk Factors

2004
Asymmetric dimethylarginine (ADMA) modulates endothelial function--therapeutic implications.
    Vascular medicine (London, England), 2003, Volume: 8, Issue:3

    Topics: Animals; Arginine; Cardiovascular Diseases; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide Synthase; Up-Regulation

2003
[Asymmetrical methylarginine (ADMA) as a cardiovascular risk factor: epidemiological and prospective data].
    Deutsche medizinische Wochenschrift (1946), 2004, Apr-08, Volume: 129, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cells, Cultured; Child; Coronary Disease; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Free Radicals; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Nitric Oxide Synthase; Oxidative Stress; Pre-Eclampsia; Pregnancy; Prospective Studies; Rabbits; Regression Analysis; Renal Dialysis; Risk Factors; Stroke

2004
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Diabetes Mellitus; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Mice; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pre-Eclampsia; Pregnancy; Protein-Arginine N-Methyltransferases; Renal Insufficiency

2004
The pivotal role of nitric oxide for vascular health.
    The Canadian journal of cardiology, 2004, Volume: 20 Suppl B

    Topics: Arginine; Arteriosclerosis; Cardiovascular Diseases; Disease Progression; Endothelium, Vascular; Female; Homeostasis; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Predictive Value of Tests; Risk Factors; Sensitivity and Specificity; Survival Analysis

2004
Asymmetric dimethylarginine (ADMA) and acute vascular events.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 348, Issue:1-2

    Topics: Acute Disease; Angina Pectoris; Arginine; Cardiovascular Diseases; Humans; Myocardial Infarction; Stroke

2004
Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, explains the "L-arginine paradox" and acts as a novel cardiovascular risk factor.
    The Journal of nutrition, 2004, Volume: 134, Issue:10 Suppl

    Topics: Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide Synthase; Risk Factors

2004
[Asymmetric dimethylarginine and endothelial dysfunction].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9

    Topics: Amidohydrolases; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Hemodynamics; Humans; Methylation; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Renin-Angiotensin System

2004
L-Arginine improves vascular function by overcoming deleterious effects of ADMA, a novel cardiovascular risk factor.
    Alternative medicine review : a journal of clinical therapeutic, 2005, Volume: 10, Issue:1

    Topics: Arginine; Arteriosclerosis; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III

2005
Endothelial cell dysfunction: the syndrome in making.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Animals; Apoptosis; Arginine; Cardiovascular Diseases; Cellular Senescence; Endothelium, Vascular; Glycation End Products, Advanced; Humans; Hyperhomocysteinemia; Kidney Diseases; Models, Biological; Oxidative Stress; Syndrome

2005
Clinical epidemiology of major nontraditional risk factors in peritoneal dialysis patients.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2005, Volume: 25 Suppl 3

    Topics: Arginine; Autonomic Nervous System Diseases; C-Reactive Protein; Cardiovascular Diseases; Humans; Hyperhomocysteinemia; Inflammation; Italy; Kidney Failure, Chronic; Nitric Oxide Synthase; Norepinephrine; Peritoneal Dialysis; Risk Factors

2005
Asymmetric dimethylarginine: a cardiovascular risk factor and a uremic toxin coming of age?
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 46, Issue:2

    Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Carotid Arteries; Carotid Stenosis; Cross-Sectional Studies; Endocrine System Diseases; Endothelium, Vascular; Haplorhini; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Nitric Oxide; Rats; Rats, Inbred Dahl; Renal Dialysis; Risk Factors; Sodium Chloride, Dietary; Tunica Intima; Tunica Media; Uremia

2005
Elevated levels of asymmetric dimethylarginine (ADMA) as a marker of cardiovascular disease and mortality.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide; Prognosis

2005
Measurement of asymmetric dimethylarginine in plasma: methodological considerations and clinical relevance.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Animals; Arginine; Cardiovascular Diseases; Homocysteine; Humans; Risk Factors; Sensitivity and Specificity

2005
[Molecular mechanisms of dysfunction of vascular endothelium].
    Kardiologiia, 2005, Volume: 45, Issue:12

    Topics: Adult; Animals; Apoptosis; Arginine; Atherosclerosis; Cardiovascular Diseases; Cells, Cultured; Child; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Epoprostenol; Female; GTP-Binding Proteins; Hemodynamics; Humans; Macrophages; Male; Multienzyme Complexes; Mutation; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Pregnancy; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Risk Factors; RNA, Messenger

2005
ADMA: its role in vascular disease.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Mice; Mice, Transgenic; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Risk Factors

2005
Asymmetric dimethylarginine (ADMA) and cardiovascular disease: insights from prospective clinical trials.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Vasodilation

2005
ADMA and hyperhomocysteinemia.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Nitric Oxide Synthase Type III; Risk Factors; Superoxides; Vasodilation

2005
Insulin resistance: potential role of the endogenous nitric oxide synthase inhibitor ADMA.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Animals; Arginine; Cardiovascular Diseases; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Metabolic Syndrome; Nitric Oxide; Nitric Oxide Synthase; Randomized Controlled Trials as Topic; Risk Factors; Vasodilation

2005
DDAH gene and cardiovascular risk.
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Humans; Hypertension; Male; Mutation; Polymorphism, Genetic; Risk Factors

2005
Pharmacotherapies and their influence on asymmetric dimethylargine (ADMA).
    Vascular medicine (London, England), 2005, Volume: 10 Suppl 1

    Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Nitric Oxide; Nitric Oxide Synthase; Protein-Arginine N-Methyltransferases; Renal Insufficiency

2005
[The best of epidemiology and cardiovascular prevention in 2005].
    Archives des maladies du coeur et des vaisseaux, 2006, Volume: 99 Spec No 1, Issue:1

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Complications; Environmental Pollutants; Humans; Metabolic Syndrome; Publishing; Risk Factors; Smoking

2006
Asymmetric dimethylarginine (ADMA): a cardiovascular and renal risk factor on the move.
    Journal of hypertension, 2006, Volume: 24, Issue:4

    Topics: Arginine; Cardiovascular Diseases; Humans; Renal Insufficiency; Risk Factors

2006
[Asymmetric dimethylarginine--a novel cardiovascular risk factor].
    Vnitrni lekarstvi, 2006, Volume: 52, Issue:3

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Endothelium, Vascular; Humans; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Vasodilation

2006
[The importance of regulation of endogenous methylarginine concentrations in clinical practice].
    Przeglad lekarski, 2005, Volume: 62, Issue:12

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Humans; Protein-Arginine N-Methyltransferases

2005
[Nitric oxide].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 5

    Topics: Adiponectin; Aldosterone; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Nitric Oxide Synthase Type III; Stem Cells; Stress, Mechanical

2006
Arginine, arginine analogs and nitric oxide production in chronic kidney disease.
    Nature clinical practice. Nephrology, 2006, Volume: 2, Issue:4

    Topics: Absorption; Amidohydrolases; Arginine; Biological Availability; Cardiovascular Diseases; Chronic Disease; Comorbidity; Enzyme Inhibitors; Humans; Kidney; Kidney Diseases; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Genetic

2006
Asymmetric dimethylarginine (ADMA) a novel cardiovascular risk factor--evidence from epidemiological and prospective clinical trials.
    Pharmacological reports : PR, 2006, Volume: 58 Suppl

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Cross-Sectional Studies; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Prospective Studies; Risk Factors

2006
The past, presence and future of ADMA in nephrology.
    Nephrologie & therapeutique, 2007, Volume: 3, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Enzyme Inhibitors; Humans; Kidney Diseases; Kidney Function Tests; Nitric Oxide Synthase; Risk Factors

2007
C-reactive protein and asymmetric dimethylarginine: markers or mediators in cardiovascular disorders?
    Current pharmaceutical design, 2007, Volume: 13, Issue:16

    Topics: Animals; Arginine; Atherosclerosis; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Humans; Inflammation; Nitric Oxide; Risk Assessment; Risk Factors

2007
Asymmetric dimethylarginine (ADMA) is a novel emerging risk factor for cardiovascular disease and the development of renal injury in chronic kidney disease.
    Clinical and experimental nephrology, 2007, Volume: 11, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Chronic Disease; Endothelium, Vascular; Humans; Kidney Diseases; Nitric Oxide; Nitric Oxide Synthase

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarkers; Bone Resorption; Calcinosis; Calcium; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Cohort Studies; Creatinine; Cystatin C; Cystatins; Diabetes Complications; Disease Progression; Dogs; Dyslipidemias; Endothelium, Vascular; Glomerular Filtration Rate; Humans; Hypertension, Renal; Inflammation Mediators; Kidney Diseases; Oxidative Stress; Phosphates; Renin-Angiotensin System; Risk Factors

2007
Arginase: a critical regulator of nitric oxide synthesis and vascular function.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:9

    Topics: Animals; Arginase; Arginine; Cardiovascular Diseases; Cell Proliferation; Collagen; Endothelium, Vascular; Homeostasis; Humans; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Urea

2007
Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Kidney; Kidney Diseases; Liver Diseases; Nitric Oxide; Nitric Oxide Synthase; Vasodilation

2007
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle?
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:2

    Topics: Albuminuria; Arginine; Cardiovascular Diseases; Chronic Disease; Endothelium, Vascular; Humans; Kidney Diseases; Ossification, Heterotopic; Oxidative Stress; Risk Assessment; Uremia

2008

Trials

15 trial(s) available for n,n-dimethylarginine and Cardiovascular Diseases

ArticleYear
Effect of Febuxostat on the Endothelial Dysfunction in Hemodialysis Patients: A Randomized, Placebo-Controlled, Double-Blinded Study.
    American journal of nephrology, 2017, Volume: 45, Issue:5

    Topics: Administration, Oral; Adult; Alanine Transaminase; Arginine; Aspartate Aminotransferases; C-Reactive Protein; Cardiovascular Diseases; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Febuxostat; Female; Humans; Incidence; Kidney Failure, Chronic; Male; Middle Aged; Pancytopenia; Placebos; Prospective Studies; Renal Dialysis; Risk Factors; Treatment Outcome; Uric Acid; Xanthine Oxidase

2017
Lifestyle modification decreases arterial stiffness and plasma asymmetric dimethylarginine level in overweight and obese men.
    Coronary artery disease, 2013, Volume: 24, Issue:7

    Topics: Adult; Animals; Ankle Brachial Index; Arginine; Biomarkers; Caloric Restriction; Cardiovascular Diseases; Down-Regulation; Exercise; Humans; Male; Middle Aged; Obesity; Overweight; Pulse Wave Analysis; Risk Reduction Behavior; Time Factors; Treatment Outcome; Vascular Stiffness

2013
Decreased levels of homoarginine and asymmetric dimethylarginine in children with type 1 diabetes: associations with cardiovascular risk factors but no effect by atorvastin.
    Journal of pediatric endocrinology & metabolism : JPEM, 2015, Volume: 28, Issue:1-2

    Topics: Adolescent; Anticholesteremic Agents; Arginine; Atorvastatin; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Glycated Hemoglobin; Heptanoic Acids; Homoarginine; Humans; Lipids; Male; Pilot Projects; Pyrroles; Risk Factors; Treatment Outcome

2015
Asymmetric Dimethylarginine Limits the Efficacy of Simvastatin Activating Endothelial Nitric Oxide Synthase.
    Journal of the American Heart Association, 2016, Apr-18, Volume: 5, Issue:4

    Topics: Aged; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Activation; Female; Humans; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Signal Transduction; Simvastatin

2016
Serum Asymmetric and Symmetric Dimethylarginine and Morbidity and Mortality in Hemodialysis Patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2017, Volume: 70, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Morbidity; Prospective Studies; Renal Dialysis

2017
Effect of supplementation with B vitamins and antioxidants on levels of asymmetric dimethylarginine (ADMA) and C-reactive protein (CRP): a double-blind, randomised, factorial design, placebo-controlled trial.
    European journal of nutrition, 2010, Volume: 49, Issue:8

    Topics: Adult; Antioxidants; Arginine; Ascorbic Acid; beta Carotene; Biomarkers; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Dietary Supplements; Double-Blind Method; Homocysteine; Humans; Male; Middle Aged; Protective Agents; Triglycerides; Vitamin B Complex; Vitamin E

2010
Randomized controlled trial of the effect of short-term coadministration of methylcobalamin and folate on serum ADMA concentration in patients receiving long-term hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2010, Volume: 55, Issue:6

    Topics: Administration, Oral; Aged; Arginine; Cardiovascular Diseases; Drug Therapy, Combination; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Risk Factors; Vitamin B 12; Vitamin B Complex

2010
Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study.
    Clinical chemistry, 2011, Volume: 57, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Coronary Disease; Female; Humans; Linear Models; Male; Middle Aged; Mortality; Predictive Value of Tests; Prognosis; Renal Insufficiency; Risk Factors

2011
Inflammatory-metabolic parameters in obese and nonobese normoandrogenemic polycystic ovary syndrome during metformin and oral contraceptive treatment.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:9

    Topics: Adult; Arginine; Body Mass Index; Cardiovascular Diseases; Contraceptives, Oral; Female; Homocysteine; Humans; Hypoglycemic Agents; Insulin Resistance; Metformin; Obesity; Polycystic Ovary Syndrome; Prospective Studies; Risk Factors; Young Adult

2011
The effect of diet and exercise on markers of endothelial function in overweight and obese women with polycystic ovary syndrome.
    Human reproduction (Oxford, England), 2012, Volume: 27, Issue:7

    Topics: Adult; Arginine; Body Mass Index; Cardiovascular Diseases; Diet; Endothelium, Vascular; Exercise; Exercise Therapy; Female; Humans; Insulin Resistance; Intercellular Adhesion Molecule-1; Overweight; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Risk; Vascular Cell Adhesion Molecule-1

2012
Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease.
    Blood purification, 2002, Volume: 20, Issue:5

    Topics: Arginine; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Renal Dialysis; Risk Factors; Sodium Chloride

2002
Oestrogen replacement therapy lowers plasma levels of asymmetrical dimethylarginine in healthy postmenopausal women.
    Clinical science (London, England : 1979), 2003, Volume: 105, Issue:1

    Topics: Analysis of Variance; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hysterectomy; Middle Aged; Nitric Oxide Synthase; Postmenopause; Protein Isoforms; Raloxifene Hydrochloride; Risk Factors; Selective Estrogen Receptor Modulators; Sensitivity and Specificity

2003
Effect of hormone replacement therapy on plasma levels of the cardiovascular risk factor asymmetric dimethylarginine: a randomized, placebo-controlled 12-week study in healthy early postmenopausal women.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:9

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Dydrogesterone; Estradiol; Estrogen Replacement Therapy; Female; Humans; Isomerism; Middle Aged; Progesterone Congeners; Promegestone; Risk Factors; Spectrometry, Fluorescence

2003
No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk.
    Clinical endocrinology, 2006, Volume: 64, Issue:5

    Topics: Adolescent; Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Pyridoxine; Risk Factors; Time Factors; Treatment Failure; Vitamin B Complex

2006
Effects of combined supplementation with B vitamins and antioxidants on plasma levels of asymmetric dimethylarginine (ADMA) in subjects with elevated risk for cardiovascular disease.
    Atherosclerosis, 2007, Volume: 193, Issue:1

    Topics: Adult; Aged; Antioxidants; Arginine; Cardiovascular Diseases; Double-Blind Method; Female; Humans; Lipids; Male; Middle Aged; Risk Factors; Vitamin B Complex

2007

Other Studies

176 other study(ies) available for n,n-dimethylarginine and Cardiovascular Diseases

ArticleYear
Design and validation of an LC-MS/MS method for simultaneous quantification of asymmetric dimethylguanidino valeric acid, asymmetric dimethylarginine and symmetric dimethylarginine in human plasma.
    Pathology, 2022, Volume: 54, Issue:5

    Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; Male; Non-alcoholic Fatty Liver Disease; Tandem Mass Spectrometry

2022
Prevalence of cardiovascular diseases in kidney transplant recipients and its relationship with asymmetric dimethylarginine, fibroblast growth factor-23 and multiple inflammatory markers.
    Acta biochimica Polonica, 2022, Nov-08, Volume: 69, Issue:4

    Topics: Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Fibroblast Growth Factor-23; Humans; Interleukin-6; Kidney Transplantation; Prevalence; Renal Insufficiency, Chronic; Water Intoxication

2022
Association of urine and plasma ADMA with atherosclerotic risk in DKD cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2023, Nov-30, Volume: 38, Issue:12

    Topics: Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus; Diabetic Nephropathies; Heart Failure; Humans; Renal Insufficiency, Chronic

2023
Successful endodontic treatment reduces serum levels of cardiovascular disease risk biomarkers-high-sensitivity C-reactive protein, asymmetric dimethylarginine, and matrix metalloprotease-2.
    International endodontic journal, 2023, Volume: 56, Issue:12

    Topics: Biomarkers; C-Reactive Protein; Cardiovascular Diseases; COVID-19; COVID-19 Vaccines; Glycated Hemoglobin; Humans; Matrix Metalloproteinase 2; Metabolic Syndrome

2023
Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS).
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chemokines; Citrulline; Cytokines; Female; Growth Hormone; Humans; Lower Extremity; Male; Metabolomics; Middle Aged; Nitric Oxide; Wounds and Injuries

2019
Blueberry anthocyanin‑enriched extract ameliorates transverse aortic constriction‑induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in mice.
    Molecular medicine reports, 2020, Volume: 21, Issue:1

    Topics: Amidohydrolases; Animals; Anthocyanins; Aortic Valve Stenosis; Apoptosis; Arginine; Blueberry Plants; Cardiovascular Diseases; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Plant Extracts; Signal Transduction

2020
Cardiovascular risk factors and the concentration of asymmetric dimethylarginine.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2020, Volume: 29, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Middle Aged; Risk Factors

2020
Asymmetric dimethylarginine and angiopoietin-like protein-2 are independent predictors of cardiovascular risk in pre-dialysis non-diabetic chronic kidney disease patients.
    International urology and nephrology, 2020, Volume: 52, Issue:7

    Topics: Adolescent; Adult; Angiopoietin-Like Protein 2; Angiopoietin-like Proteins; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Renal Insufficiency, Chronic; Risk Assessment; Young Adult

2020
Influence of Human Paraoxonase-1 Polymorphism (Q192R) on Serum Levels of Clinical Biomarkers Indicatives of Cardiovascular Diseases Risk in Mexican Women.
    Biochemical genetics, 2020, Volume: 58, Issue:5

    Topics: Adult; Arginine; Aryldialkylphosphatase; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Fatty Acid-Binding Proteins; Female; Genetic Predisposition to Disease; Heart Disease Risk Factors; Humans; Male; Mexico; MicroRNAs; Polymorphism, Genetic; Sex Factors

2020
Asymmetric dimethylarginine compartmental behavior during high-flux hemodialysis.
    Renal failure, 2020, Volume: 42, Issue:1

    Topics: Adult; Arginine; Cardiovascular Diseases; Creatinine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis; Tandem Mass Spectrometry; Urea

2020
Association of Asymmetric Dimethylarginine and Nitric Oxide with Cardiovascular Risk in Patients with End-Stage Liver Disease.
    Medicina (Kaunas, Lithuania), 2020, Nov-18, Volume: 56, Issue:11

    Topics: Adult; Arginine; Cardiovascular Diseases; End Stage Liver Disease; Heart Disease Risk Factors; Humans; Nitric Oxide; Risk Factors; Severity of Illness Index

2020
Whole-body arginine dimethylation is associated with all-cause mortality in adult renal transplant recipients.
    Amino acids, 2021, Volume: 53, Issue:4

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cause of Death; Female; Heart Disease Risk Factors; Humans; Kidney Transplantation; Male; Methylation; Middle Aged; Protein Processing, Post-Translational; Tissue Donors; Transplant Recipients

2021
Profile of new vascular damage biomarkers in middle-aged men with arterial hypertension.
    Advances in medical sciences, 2021, Volume: 66, Issue:1

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Endothelium, Vascular; Follow-Up Studies; Humans; Hypertension; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Prognosis

2021
Myeloperoxidase, asymmetric dimethyl-arginine and the renin-angiotensin-aldosterone-system in cardiovascular risk patients: Cross-sectional findings from the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.
    Clinical biochemistry, 2017, Volume: 50, Issue:13-14

    Topics: Aged; Aldosterone; Arginine; Austria; Biomarkers; Cardiovascular Diseases; Cohort Studies; Coronary Angiography; Cross-Sectional Studies; Female; Follow-Up Studies; Germany; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Male; Middle Aged; Mortality; Peroxidase; Predictive Value of Tests; Prevalence; Prospective Studies; Renin-Angiotensin System; Risk Factors

2017
Plasma Arginine/Asymmetric Dimethylarginine Ratio and Incidence of Cardiovascular Events: A Case-Cohort Study.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Chromatography, Liquid; Citrulline; Cohort Studies; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; omega-N-Methylarginine; Ornithine; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Tandem Mass Spectrometry

2017
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation.
    BMC infectious diseases, 2017, 03-29, Volume: 17, Issue:1

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; HIV Infections; Humans; Inflammation; Male; Methylamines; Middle Aged; Risk Factors; Tandem Mass Spectrometry

2017
Asymmetric dimethylarginine and arginine metabolites in women with and without a history of gestational diabetes.
    Journal of diabetes and its complications, 2017, Volume: 31, Issue:6

    Topics: Adult; Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Follow-Up Studies; Glucose Tolerance Test; Humans; Postpartum Period; Pregnancy; Prognosis

2017
Effect of arginine:lysine and glycine:methionine intake ratios on dyslipidemia and selected biomarkers implicated in cardiovascular disease: A study with hypercholesterolemic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 91

    Topics: Administration, Oral; Amino Acids; Animals; Arginine; Biomarkers; Body Weight; Cardiovascular Diseases; Dyslipidemias; Glycine; Homocysteine; Hypercholesterolemia; Lipids; Liver; Lysine; Male; Methionine; Nitric Oxide; Organ Size; Rats, Wistar

2017
Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance.
    Scientific reports, 2017, 06-06, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Amidohydrolases; Arginine; Australia; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Humans; Male; Mass Spectrometry; Middle Aged; Proton Pump Inhibitors; Risk Assessment

2017
Association between vitamin D status and asymmetric dimethylarginine (ADMA) concentration in the Korean elderly population.
    Maturitas, 2017, Volume: 102

    Topics: Aged; Aged, 80 and over; Arginine; Asian People; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Female; Humans; Longitudinal Studies; Male; Middle Aged; Vitamin D; Vitamin D Deficiency

2017
Influence on serum asymmetric dimethylarginine (ADMA) concentrations of human paraoxonase 1 polymorphism (Q192R) and exposure to polycyclic aromatic hydrocarbons (PAHs) in Mexican women, a gene-environment interaction.
    Chemosphere, 2017, Volume: 186

    Topics: Adult; Alleles; Arginine; Aryldialkylphosphatase; Biomarkers; Cardiovascular Diseases; Creatinine; Environmental Exposure; Environmental Pollutants; Female; Gene Frequency; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Humans; Mexico; Polycyclic Aromatic Hydrocarbons; Polymorphism, Genetic; Pyrenes; Risk Factors

2017
Asymmetric dimethylarginine and symmetric dimethylarginine prospectively relates to carotid wall thickening in black men: the SABPA study.
    Amino acids, 2017, Volume: 49, Issue:11

    Topics: Adult; Arginine; Black People; Cardiovascular Diseases; Carotid Intima-Media Thickness; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Regression Analysis; South America; White People

2017
Symmetric dimethylarginine (SDMA) outperforms asymmetric dimethylarginine (ADMA) and other methylarginines as predictor of renal and cardiovascular outcome in non-dialysis chronic kidney disease.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, Liquid; Disease Progression; Female; Germany; Humans; Incidence; Male; Middle Aged; omega-N-Methylarginine; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Risk Factors

2018
Serum Concentrations of New Predictive Cardiovascular Disease Biomarkers in Mexican Women Exposed to Lead.
    Archives of environmental contamination and toxicology, 2018, Volume: 74, Issue:2

    Topics: Adiponectin; Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Cardiovascular Diseases; Chemokines; Cross-Sectional Studies; Environmental Exposure; Fatty Acid-Binding Proteins; Female; Humans; Intercellular Signaling Peptides and Proteins; Lead; Male; Mexico; Middle Aged

2018
Increased Endothelial Dysfunction and Insulin Resistance in Patients with Klinefelter Syndrome.
    Endocrine, metabolic & immune disorders drug targets, 2018, Volume: 18, Issue:4

    Topics: Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cholesterol, HDL; Endothelium, Vascular; Humans; Inflammation; Inflammation Mediators; Insulin; Insulin Resistance; Klinefelter Syndrome; Male; Multivariate Analysis; Prevalence; Risk Factors; Testosterone; Turkey; Young Adult

2018
Association of endothelial dysfunction with cardiovascular risk factors and new-onset diabetes mellitus in patients with hypertension.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:5

    Topics: Aged; Arginine; Brazil; C-Reactive Protein; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Nitric Oxide Synthase; Predictive Value of Tests; Prospective Studies; Risk Factors; Triglycerides

2018
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction.
    Scientific reports, 2018, 04-30, Volume: 8, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelium; Feces; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Inflammation; Kynurenine; Male; Metabolism; Middle Aged; Neopterin; Risk Factors; RNA, Ribosomal, 16S; Tryptophan

2018
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis.
    Arthritis research & therapy, 2018, 06-08, Volume: 20, Issue:1

    Topics: Aged; Arginase; Arginine; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Comorbidity; Female; Humans; Hyperlipidemias; Hypertension; Male; Middle Aged; Prevalence; Risk Factors; United States

2018
Cyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs.
    Circulation, 2018, 11-20, Volume: 138, Issue:21

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Blood Pressure; Blood Urea Nitrogen; Cardiovascular Diseases; Celecoxib; Creatinine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Kidney; Metabolome; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteoarthritis; Placebo Effect

2018
Homoarginine/ADMA ratio and homoarginine/SDMA ratio as independent predictors of cardiovascular mortality and cardiovascular events in lower extremity arterial disease.
    Scientific reports, 2018, 09-21, Volume: 8, Issue:1

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cardiovascular System; Female; Homoarginine; Humans; Incidence; Lower Extremity; Male; Middle Aged; Prospective Studies; Risk Factors; Vascular Diseases

2018
ADMA and NT pro-BNP are associated with overall mortality in elderly.
    European journal of clinical investigation, 2019, Volume: 49, Issue:1

    Topics: Age Distribution; Aged; Aged, 80 and over; Arginine; Austria; Biomarkers; Body Mass Index; Cardiovascular Diseases; Female; Health Services for the Aged; Hospitalization; Humans; Male; Natriuretic Peptide, Brain; Peptide Fragments; Prospective Studies; Risk Factors; Sex Distribution; Survival Analysis

2019
Impact of arsenic exposure on clinical biomarkers indicative of cardiovascular disease risk in Mexican women.
    Ecotoxicology and environmental safety, 2019, Volume: 169

    Topics: Adult; Aged; Arginine; Arsenic; Biomarkers; Cardiovascular Diseases; Cross-Sectional Studies; Drinking Water; Environmental Exposure; Fatty Acid-Binding Proteins; Female; Humans; Male; Mexico; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Risk Factors; Surveys and Questionnaires; Water Pollutants, Chemical

2019
Protein-energy wasting and asymmetric dimethylarginine in peritoneal dialysis patients.
    Acta biochimica Polonica, 2018, Dec-03, Volume: 65, Issue:4

    Topics: Adiponectin; Adult; Aged; Arginine; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Energy Metabolism; Humans; Interleukin-6; Kidney Failure, Chronic; Leptin; Lipoproteins, LDL; Middle Aged; Peritoneal Dialysis; Risk Factors; Tumor Necrosis Factor-alpha

2018
Chronic intermittent hypoxia-mediated renal sympathetic nerve activation in hypertension and cardiovascular disease.
    Scientific reports, 2018, 12-18, Volume: 8, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensins; Animals; Arginine; Cardiovascular Diseases; Deoxyguanosine; Disease Models, Animal; Humans; Hypertension; Hypoxia; Kidney; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidative Stress; Sympathectomy; Sympathetic Nervous System

2018
The renal transport protein OATP4C1 mediates uptake of the uremic toxin asymmetric dimethylarginine (ADMA) and efflux of cardioprotective L-homoarginine.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Arginine; Cardiovascular Diseases; HEK293 Cells; Homoarginine; Humans; Inhibitory Concentration 50; Kidney; Kinetics; Organic Anion Transporters; Toxins, Biological

2019
Plasma ADMA, urinary ADMA excretion, and late mortality in renal transplant recipients.
    Amino acids, 2019, Volume: 51, Issue:6

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Humans; Kidney Transplantation; Male; Middle Aged; Netherlands; Tandem Mass Spectrometry; Transplant Recipients

2019
Establishment of reference values for the lysine acetylation marker N
    Amino acids, 2019, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Carnitine; Chromatography, Liquid; Citrulline; Creatinine; Female; Homoarginine; Humans; Lysine; Male; Middle Aged; Ornithine; Reference Values; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Young Adult

2019
Heat-assisted extraction for the determination of methylarginines in serum by CE.
    Electrophoresis, 2013, Volume: 34, Issue:11

    Topics: Arginine; Cardiovascular Diseases; Electrophoresis, Capillary; Hot Temperature; Humans; omega-N-Methylarginine; Solid Phase Extraction

2013
Association of lipid peroxidation with endothelial dysfunction in patients with overt hypothyroidism.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2013, Volume: 121, Issue:5

    Topics: Adult; Antioxidants; Arginine; Cardiovascular Diseases; Case-Control Studies; Endothelium, Vascular; Female; Humans; Hypothyroidism; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide; Risk Factors

2013
Editorial (hot topic: cardiovascular disease biomarkers: from tradition to modernity).
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:2

    Topics: Adiponectin; Arginine; Biomarkers; Cardiovascular Diseases; Cystatin C; Endothelins; Glycopeptides; Humans; MicroRNAs; Natriuretic Peptide, Brain; Peptide Fragments; Peroxidase; Predictive Value of Tests; Troponin

2013
Asymmetric dimethylarginine predicts survival in the elderly.
    Age (Dordrecht, Netherlands), 2013, Volume: 35, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cardiovascular Diseases; Cause of Death; Chromatography, Liquid; Female; Follow-Up Studies; Humans; Italy; Male; Population Surveillance; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Tandem Mass Spectrometry; Time Factors

2013
Endothelial dysfunction, inflammation and malnutrition markers as predictors of mortality in dialysis patients: multimarker approach.
    International urology and nephrology, 2013, Volume: 45, Issue:6

    Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Inflammation; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Malnutrition; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Renal Dialysis; Risk Assessment; ROC Curve; Serum Albumin; Serum Amyloid A Protein

2013
Elevated circulating levels and tissue expression of pentraxin 3 in uremia: a reflection of endothelial dysfunction.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Endothelium; Female; Gene Expression; Humans; Kidney; Male; Middle Aged; Prognosis; Renal Insufficiency, Chronic; RNA, Messenger; Serum Amyloid P-Component; Subcutaneous Fat, Abdominal; Uremia; Vascular Resistance

2013
Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.
    Circulation, 2013, Aug-20, Volume: 128, Issue:8

    Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Esomeprazole; Gastroesophageal Reflux; Humans; Lansoprazole; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Proton Pump Inhibitors; Risk Factors; Vasodilation

2013
Plasma asymmetric dimethylarginine and adverse events in patients with atrial fibrillation referred for coronary angiogram.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Aged; Aged, 80 and over; Arginine; Atrial Fibrillation; Cardiovascular Diseases; Coronary Angiography; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Referral and Consultation; Risk Assessment; Risk Factors; Stroke; Survival Rate; Time Factors

2013
Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: the sympathetic activity and ambulatory blood pressure in Africans study.
    Psychosomatic medicine, 2013, Volume: 75, Issue:8

    Topics: Acute Disease; Adult; Arginine; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Chronic Disease; Cold Temperature; Cross-Sectional Studies; Disease Susceptibility; Female; Hemodynamics; Humans; Male; Middle Aged; Motor Activity; Nitric Oxide; Pressure; Rest; South Africa; Stress, Psychological; Stroop Test; White People

2013
Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas heart study.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:11

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Risk Factors; Texas

2013
The cardiovascular risk marker asymmetric dimethylarginine is elevated in asymptomatic, untreated HIV-1 infection and correlates with markers of immune activation and disease progression.
    Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 5

    Topics: Adenosine Deaminase; Adult; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Cross-Sectional Studies; Female; HIV Infections; HIV Seropositivity; Humans; Immunoglobulin G; Interleukin-6; Male; Viral Load

2014
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Environment; Female; Genotype; Humans; Intermittent Claudication; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors

2014
Lipoprotein apheresis reduces biomarkers of plaque destabilization and cardiovascular risk.
    Journal of clinical apheresis, 2014, Volume: 29, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; Blood Component Removal; C-Reactive Protein; Cardiovascular Diseases; Female; Humans; Lipoproteins; Male; Matrix Metalloproteinase 9; Middle Aged; Plaque, Atherosclerotic; Pregnancy-Associated Plasma Protein-A; Vascular Cell Adhesion Molecule-1

2014
Asymmetric dimethylarginine is not associated with subendocardial viability ratio in Rheumatoid Arthritis.
    International journal of cardiology, 2014, Mar-01, Volume: 172, Issue:1

    Topics: Aged; Arginine; Arthritis, Rheumatoid; Cardiovascular Diseases; Endocardium; Female; Humans; Male; Middle Aged; Risk Assessment

2014
Asymmetric dimethyl L-arginine, nitric oxide and cardiovascular disease in adolescent type 1 diabetics.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:5-6

    Topics: Adolescent; Arginine; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Egypt; Electrocardiography; Female; Humans; Lipids; Male; Nitric Oxide; Ultrasonography

2014
Asymmetric dimethylarginine responses during interferon-α-induced depression in patients with chronic hepatitis C infection.
    Psychosomatic medicine, 2014, Volume: 76, Issue:3

    Topics: Adult; Analysis of Variance; Antiviral Agents; Arginine; Cardiovascular Diseases; Chromatography, Liquid; Depression; Depressive Disorder; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Nitric Oxide Synthase; Prospective Studies; Psychiatric Status Rating Scales; Regression Analysis; Ribavirin; Risk Factors; Time Factors

2014
The effects of Ramadan fasting on endothelial function in patients with cardiovascular diseases.
    European journal of clinical nutrition, 2014, Volume: 68, Issue:7

    Topics: Adult; Arginine; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Artery Disease; Endothelium, Vascular; Fasting; Humans; Islam; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Peripheral Arterial Disease; Vascular Endothelial Growth Factor A

2014
Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Cardiovascular Diseases; Female; Humans; Incidence; Male; Middle Aged; Young Adult

2014
GC-MS and GC-MS/MS measurement of the cardiovascular risk factor homoarginine in biological samples.
    Amino acids, 2014, Volume: 46, Issue:9

    Topics: Arginine; Cardiovascular Diseases; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; Humans; Male; Risk Factors; Sputum

2014
Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania.
    Clinical chemistry and laboratory medicine, 2014, Volume: 52, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Female; Homoarginine; Humans; Male; Middle Aged; Reference Values; Renal Insufficiency, Chronic; Risk Factors; Tandem Mass Spectrometry

2014
Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin.
    Journal of the American Heart Association, 2014, Jul-18, Volume: 3, Issue:4

    Topics: Aged; Arginine; Aspirin; Biomarkers; Cardiovascular Diseases; Case-Control Studies; CD40 Ligand; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxane B2; Wnt Signaling Pathway

2014
Aging of the nitric oxide system: are we as old as our NO?
    Journal of the American Heart Association, 2014, Aug-18, Volume: 3, Issue:4

    Topics: Aged; Aging; Arginine; Blood Platelets; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Prospective Studies

2014
Cumulative inflammation associates with asymmetric dimethylarginine in rheumatoid arthritis: a 6 year follow-up study.
    Rheumatology (Oxford, England), 2015, Volume: 54, Issue:7

    Topics: Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Disease Progression; Female; Follow-Up Studies; Humans; Inflammation; Longitudinal Studies; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Regression Analysis; Risk Factors; Severity of Illness Index

2015
Cardiovascular-renal changes after kidney donation: one-year follow-up study.
    Transplantation, 2015, Volume: 99, Issue:4

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Interleukin-6; Kidney Diseases; Male; Middle Aged; Multivariate Analysis; Nephrectomy; Prospective Studies; Risk Factors; Time Factors; Tissue Donors; Treatment Outcome; Uric Acid; Vascular Cell Adhesion Molecule-1; Vasodilation; Young Adult

2015
Monocyte activation, but not microbial translocation, is independently associated with markers of endovascular dysfunction in HIV-infected patients receiving cART.
    Journal of acquired immune deficiency syndromes (1999), 2014, Dec-01, Volume: 67, Issue:4

    Topics: Adult; Aged; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Arginine; Bacterial Translocation; Biomarkers; Cardiovascular Diseases; Female; Fibrin Fibrinogen Degradation Products; HIV Infections; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Middle Aged; Monocytes

2014
Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine: novel explanation of cardiovascular side effects associated with anti-inflammatory drugs.
    Circulation, 2015, Feb-17, Volume: 131, Issue:7

    Topics: Adult; Animals; Anti-Inflammatory Agents; Arginine; Biomarkers; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Young Adult

2015
Investigation of subclinical atherosclerosis in psoriatic arthritis patients with minimal disease activity.
    Rheumatology international, 2015, Volume: 35, Issue:8

    Topics: Adult; Arginine; Arthritis, Psoriatic; Asymptomatic Diseases; Atherosclerosis; Brachial Artery; Cardiovascular Diseases; Carotid Arteries; Carotid Intima-Media Thickness; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Severity of Illness Index; Vasodilation

2015
Interleukin-6 and asymmetric dimethylarginine are associated with platelet activation after percutaneous angioplasty with stent implantation.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Arginine; Blood Platelets; C-Reactive Protein; Cardiovascular Diseases; Creatinine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Integrin beta3; Interleukin-6; Male; Middle Aged; Monocytes; P-Selectin; Platelet Activation; Platelet Aggregation; Platelet Membrane Glycoprotein IIb; Risk Factors; Smoking; Stents

2015
The role of plasma triglyceride/high-density lipoprotein cholesterol ratio to predict cardiovascular outcomes in chronic kidney disease.
    Lipids in health and disease, 2015, Apr-16, Volume: 14

    Topics: Adult; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, HDL; Female; Glomerular Filtration Rate; Humans; Longitudinal Studies; Male; Middle Aged; Parathyroid Hormone; Renal Insufficiency, Chronic; Retrospective Studies; Serum Albumin; Triglycerides

2015
Asymmetric dimethylarginine is negatively correlated with hyperglycemia in children.
    Endocrine journal, 2015, Volume: 62, Issue:6

    Topics: Adolescent; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hyperglycemia; Japan; Male; Pediatric Obesity; Risk

2015
The relationship between serum asymmetric dimethylarginine levels and subjective sleep quality in normotensive patients with type 2 diabetes mellitus.
    The Korean journal of internal medicine, 2015, Volume: 30, Issue:3

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors; Sleep; Sleep Wake Disorders; Surveys and Questionnaires

2015
Heat Shock Proteins, L-Arginine, and Asymmetric Dimethylarginine Levels in Patients With Obstructive Sleep Apnea Syndrome.
    Archivos de bronconeumologia, 2015, Volume: 51, Issue:11

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Disease Susceptibility; Endothelium, Vascular; Female; Heat-Shock Proteins; Humans; Hypercholesterolemia; Hypertension; Male; Middle Aged; Obesity; Oxidative Stress; Polysomnography; Risk Factors; Sleep Apnea, Obstructive; Smoking; Turkey

2015
ADMA and arginine derivatives in relation to non-invasive vascular function in the general population.
    Atherosclerosis, 2016, Volume: 244

    Topics: Adult; Aged; Arginine; Blood Flow Velocity; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; Enzyme Inhibitors; Female; Germany; Humans; Male; Middle Aged; Nitric Oxide Synthase; Population Surveillance; Prevalence; Retrospective Studies; Vasodilation

2016
Soluble receptor and gene polymorphism for AGE: relationship with obesity and cardiovascular risks.
    Pediatric research, 2016, Volume: 80, Issue:1

    Topics: Adolescent; Alleles; Arginine; Atherosclerosis; Biomarkers; Blood Pressure; Cardiovascular Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Cross-Sectional Studies; Female; Humans; Lipids; Male; Pediatric Obesity; Polymorphism, Genetic; Receptor for Advanced Glycation End Products; Regression Analysis; Risk Factors

2016
Relationship between FEV
    Aging clinical and experimental research, 2017, Volume: 29, Issue:2

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Endothelium, Vascular; Female; Forced Expiratory Volume; Humans; Inflammation; Interleukin-6; Italy; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Risk Factors; Statistics as Topic; Vascular Stiffness

2017
Relevance of uric acid and asymmetric dimethylarginine for modeling cardiovascular risk prediction in chronic kidney disease patients.
    International urology and nephrology, 2016, Volume: 48, Issue:7

    Topics: Academic Medical Centers; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cause of Death; Cohort Studies; Female; Humans; Kaplan-Meier Estimate; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Assessment; Severity of Illness Index; Survival Analysis; Uric Acid

2016
Osteoprotegerin, RANKL, ADMA, and Fetuin-A serum levels in children with type I diabetes mellitus.
    Pediatric diabetes, 2017, Volume: 18, Issue:4

    Topics: Adolescent; alpha-2-HS-Glycoprotein; Arginine; Biomarkers; Cardiovascular Diseases; Child; Cohort Studies; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Cardiomyopathies; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Greece; Humans; Male; Osteoprotegerin; RANK Ligand; Reproducibility of Results

2017
Elevated plasma ADMA contributes to development of endothelial dysfunction in children with acute lymphoblastic leukemia.
    Postepy higieny i medycyny doswiadczalnej (Online), 2016, Jun-01, Volume: 70, Issue:0

    Topics: Adolescent; Arginine; Cardiovascular Diseases; Child; Child, Preschool; Endothelial Cells; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Female; Humans; Infant; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors

2016
Serum asymmetric dimethylarginine and arginine levels predict microvascular and macrovascular complications in type 2 diabetes mellitus.
    Diabetes/metabolism research and reviews, 2017, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxidative Stress; Prognosis; Prospective Studies; Risk Factors; Young Adult

2017
[Effect of asymmetrical dimethylarginine for predicting pro-thrombotic risk in atrial fibrillation].
    Zhonghua yi xue za zhi, 2016, Jul-12, Volume: 96, Issue:26

    Topics: Arginine; Atrial Fibrillation; Cardiovascular Diseases; Heart Atria; Humans; Stereoisomerism; Thrombosis

2016
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.
    Scientific reports, 2016, 10-18, Volume: 6

    Topics: Aminoisobutyric Acids; Animals; Arginine; Cardiovascular Diseases; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk; RNA, Small Interfering; Transaminases

2016
Carotid Plaque Score and Risk of Cardiovascular Mortality in the Oldest Old: Results from the TOOTH Study.
    Journal of atherosclerosis and thrombosis, 2018, Jan-01, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Female; Humans; Japan; Kaplan-Meier Estimate; Male; Multivariate Analysis; Proportional Hazards Models; Risk Factors; Sensitivity and Specificity; Treatment Outcome

2018
Oxidative stress and asymmetric dimethylarginine are associated with cardiovascular complications in hemodialysis patients: improvements by L-arginine intake.
    Kidney & blood pressure research, 2008, Volume: 31, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Case-Control Studies; Homocysteine; Humans; Kidney Failure, Chronic; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Peroxidase; Renal Dialysis; Risk Factors

2008
Asymmetric dimethylarginine (ADMA) has a role in regulating systemic vascular tone in young healthy subjects: the cardiovascular risk in young Finns study.
    American journal of hypertension, 2008, Volume: 21, Issue:8

    Topics: Adult; Arginine; Blood Pressure; Cardiovascular Diseases; Female; Finland; Humans; Kidney; Lipids; Male; Nitric Oxide; Risk Factors; Vascular Resistance; Vasoconstriction; Young Adult

2008
[Asymmetric dimethil-arginine (ADMA) as a link between insulin resistance and atherosclerosis].
    Ideggyogyaszati szemle, 2008, May-30, Volume: 61, Issue:5-6

    Topics: Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Carotid Stenosis; Chromatography; Enzyme Inhibitors; Female; Homocysteine; Humans; Insulin Resistance; Linear Models; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography, Doppler, Color

2008
Obstructive sleep apnoea syndrome is associated with enhanced sub-clinical inflammation and asymmetric dimethyl-arginine levels in hypertensives.
    Journal of human hypertension, 2009, Volume: 23, Issue:1

    Topics: Adult; Arginine; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Hypertension; Inflammation; Interleukin-18; Interleukin-6; Male; Middle Aged; Risk Factors; Severity of Illness Index; Sleep Apnea, Obstructive; Tumor Necrosis Factor-alpha

2009
Increased plasma levels of asymmetric dimethylarginine and soluble CD40 ligand in patients with sleep apnea.
    Respiration; international review of thoracic diseases, 2009, Volume: 77, Issue:1

    Topics: Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Case-Control Studies; CD40 Ligand; Endothelin-1; Humans; Male; Middle Aged; Risk Factors; Sleep Apnea, Obstructive

2009
Smoker's paradox in heart failure: might asymmetric dimethylarginine be the possible explanation?
    European heart journal, 2008, Volume: 29, Issue:23

    Topics: Arginine; Cardiovascular Diseases; Heart Failure; Hospital Mortality; Humans; Smoking

2008
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:3

    Topics: Arginine; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Metabolic Syndrome

2009
The beneficial effects of angiotensin-converting enzyme inhibitors on serum asymmetric dimethylarginine levels in the patients with cardiovascular disease.
    International journal of cardiology, 2010, Jun-25, Volume: 142, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Cardiovascular Diseases; Humans

2010
Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population.
    Atherosclerosis, 2009, Volume: 205, Issue:1

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Proportional Hazards Models; Prospective Studies; Risk

2009
Clinical implications of elevated asymmetric dimethylarginine in chronic kidney disease and end-stage renal disease.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2009, Volume: 19, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Carotid Arteries; Humans; Kidney Diseases; Kidney Failure, Chronic; Risk Factors; Uremia

2009
Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community.
    Circulation, 2009, Mar-31, Volume: 119, Issue:12

    Topics: Aged; Arginine; Cardiovascular Diseases; Cause of Death; Diabetes Mellitus; Follow-Up Studies; Humans; Incidence; Middle Aged; Mortality; Predictive Value of Tests; Prognosis; Proportional Hazards Models

2009
HDL-cholesterol, blood pressure, and asymmetric dimethylarginine are significantly associated with arterial wall thickness in children.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:6

    Topics: Arginine; Biomarkers; Blood Pressure; Cardiovascular Diseases; Carotid Arteries; Carotid Artery Diseases; Child; Cholesterol, HDL; Cross-Sectional Studies; Disease Progression; Female; Humans; Male; New South Wales; Risk Factors; Tunica Intima; Tunica Media; Ultrasonography

2009
Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort.
    Clinical chemistry, 2009, Volume: 55, Issue:8

    Topics: Age Factors; Aged; Arginine; Cardiovascular Diseases; Chromatography, Liquid; Cohort Studies; Female; Homocysteine; Humans; Male; Middle Aged; Multivariate Analysis; Reference Standards; Sensitivity and Specificity; Sex Factors; Tandem Mass Spectrometry

2009
Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Citrulline; Coronary Artery Disease; Creatinine; Female; Humans; Lysine; Male; Metabolomics; Methylation; Middle Aged; Nitric Oxide Synthase; Odds Ratio; omega-N-Methylarginine; Ornithine; Prognosis; Prospective Studies; Protein Processing, Post-Translational; Risk Assessment; Risk Factors; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors

2009
Plasma concentrations of the cardiovascular risk factor asymmetric dimethylarginine (ADMA) are increased in patients with HIV-1 infection and correlate with immune activation markers.
    Pharmacological research, 2009, Volume: 60, Issue:6

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cohort Studies; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Risk Factors; Th1 Cells; Young Adult

2009
Determinants of occurrence of aortic sclerosis in an aging population.
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:8

    Topics: Age Factors; Aged; Aorta; Aortic Valve; Aortic Valve Stenosis; Arginine; Biomarkers; Blood Platelets; Body Mass Index; Calcinosis; Cardiovascular Diseases; Cross-Sectional Studies; Disease Progression; Echocardiography, Doppler; Elasticity; Endothelium, Vascular; Female; Heart Valve Diseases; Humans; Linear Models; Male; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Platelet Aggregation; Prospective Studies; Pulsatile Flow; Risk Assessment; Risk Factors; Sclerosis

2009
Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients.
    Kidney international, 2010, Volume: 77, Issue:1

    Topics: Adult; Arginine; Cardiovascular Diseases; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Middle Aged; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome

2010
Asymmetric dimethylarginine: understanding the physiology, genetics, and clinical relevance of this novel biomarker. Proceedings of the 4th International Symposium on ADMA.
    Pharmacological research, 2009, Volume: 60, Issue:6

    Topics: Arginine; Austria; Biomarkers; Cardiovascular Diseases; Humans; Internationality; Nitric Oxide

2009
Distribution of asymmetric dimethylarginine among 980 healthy, older adults of different ethnicities.
    Clinical chemistry, 2010, Volume: 56, Issue:1

    Topics: Aged; Arginine; Asian People; Black People; Cardiovascular Diseases; Cystatin C; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Hispanic or Latino; Humans; Male; Middle Aged; Regression Analysis; Risk Factors; White People

2010
Circulating angiopoietin-2 levels increase with progress of chronic kidney disease.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:8

    Topics: Adult; Aged; Angiopoietin-2; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Chronic Disease; Disease Progression; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Middle Aged; Nephrectomy; Risk Factors; Tissue Donors

2010
Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine.
    The American journal of pathology, 2010, Volume: 176, Issue:5

    Topics: Amidohydrolases; Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Humans; Male; Mice; Mice, Transgenic; Models, Genetic; Nitric Oxide; Risk

2010
Association between exaggerated blood pressure response to exercise and serum asymmetric dimethylarginine levels.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:6

    Topics: Adult; Arginine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Exercise; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Predictive Value of Tests

2010
[Prevalence of cardiovascular disease in uraemia and relevance of cardiovascular risk factors].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2010, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Blood Proteins; Cardiovascular Diseases; Comorbidity; Cross-Sectional Studies; Diabetes Complications; Female; Humans; Hyperhomocysteinemia; Hyperlipidemias; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prevalence; Risk Factors; Smoking; Stroke Volume; Ultrasonography; Uremia

2010
HPLC determination of plasma dimethylarginines: method validation and preliminary clinical application.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Nov-11, Volume: 411, Issue:21-22

    Topics: Adolescent; Adult; Aged; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Creatine; Endothelium, Vascular; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Middle Aged; Renal Insufficiency, Chronic; Young Adult

2010
Increased production of asymmetric dimethylarginine (ADMA) in ankylosing spondylitis: association with other clinical and laboratory parameters.
    Joint bone spine, 2011, Volume: 78, Issue:2

    Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Risk Factors; Spondylitis, Ankylosing

2011
Adipokines, endothelial dysfunction and nutritional status in peritoneal dialysis patients.
    Scandinavian journal of urology and nephrology, 2010, Volume: 44, Issue:6

    Topics: Adiponectin; Adult; Aged; Aldehydes; Arginine; Biomarkers; Body Mass Index; Body Weight; C-Reactive Protein; Cardiovascular Diseases; Endothelium; Female; Humans; Inflammation; Interleukin-6; Leptin; Lipoproteins, LDL; Male; Malnutrition; Malondialdehyde; Middle Aged; Nutritional Status; Oxidative Stress; Peritoneal Dialysis; Risk Factors; Tumor Necrosis Factor-alpha

2010
Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study.
    Atherosclerosis, 2010, Volume: 212, Issue:2

    Topics: Adult; Arginine; Brachial Artery; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cohort Studies; Endothelium, Vascular; Female; Finland; Humans; Male; Middle Aged; Multivariate Analysis; Risk Factors

2010
Evaluation of asymmetric dimethylarginine, nitric oxide levels and associated independent variables in obese and lean patients with polycystic ovarian syndrome.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2011, Volume: 27, Issue:9

    Topics: Adolescent; Adult; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Cholesterol; Female; Hormones; Humans; Nitric Oxide; Obesity; Polycystic Ovary Syndrome; Risk Factors; Young Adult

2011
Serum asymmetric dimethylarginine levels in normotensive obese individuals.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:11

    Topics: Adult; Arginine; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Enzyme Inhibitors; Humans; Male; Middle Aged; Obesity; Risk Factors

2010
Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus.
    Clinical endocrinology, 2011, Volume: 74, Issue:4

    Topics: Aged; Arginine; Asian People; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Regression Analysis; Risk Factors

2011
Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease.
    Journal of internal medicine, 2011, Volume: 269, Issue:3

    Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Enzyme Inhibitors; Epidemiologic Methods; Female; Germany; Humans; Male; Nitric Oxide Synthase; Peripheral Arterial Disease; Prognosis

2011
Asymmetric dimethylarginine in young people with Type 1 diabetes: a paradoxical association with HbA(1c).
    Diabetic medicine : a journal of the British Diabetic Association, 2011, Volume: 28, Issue:6

    Topics: Adolescent; Albuminuria; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Child; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Female; Glycated Hemoglobin; Humans; Longitudinal Studies; Male; Risk Factors

2011
The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study.
    Cardiovascular diabetology, 2011, Feb-09, Volume: 10

    Topics: Aged; Amidohydrolases; Analysis of Variance; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cohort Studies; Coronary Angiography; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Insulin; Insulin Resistance; Kaplan-Meier Estimate; Linear Models; Linkage Disequilibrium; Logistic Models; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Taiwan

2011
NO problem: arterial and venous endothelial function and erectile dysfunction.
    European urology, 2011, Volume: 59, Issue:6

    Topics: Arginine; Arteries; Biomarkers; Blood Flow Velocity; Cardiovascular Diseases; Endothelium, Vascular; Humans; Impotence, Vasculogenic; Male; Nitric Oxide; Penile Erection; Penis; Predictive Value of Tests; Regional Blood Flow; Risk Assessment; Risk Factors; Severity of Illness Index; Ultrasonography, Doppler, Color; Up-Regulation; Veins

2011
Relationship of asymmetric dimethylarginine with penile Doppler ultrasound parameters in men with vasculogenic erectile dysfunction.
    European urology, 2011, Volume: 59, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Arginine; Arteries; Biomarkers; Blood Flow Velocity; Cardiovascular Diseases; Case-Control Studies; Greece; Humans; Impotence, Vasculogenic; Male; Middle Aged; Penile Erection; Penis; Predictive Value of Tests; Regional Blood Flow; Regression Analysis; Retrospective Studies; Risk Assessment; Risk Factors; ROC Curve; Severity of Illness Index; Ultrasonography, Doppler, Color; Up-Regulation; Veins

2011
Relationships between serum levels of thyroid hormones and serum concentrations of asymmetric dimethylarginine (ADMA) and N-terminal-pro-B-type natriuretic peptide (NT-proBNP) in patients with Graves' disease.
    Endocrine, 2011, Volume: 39, Issue:3

    Topics: Adult; Arginine; Biomarkers; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Graves Disease; Heart Rate; Hospitals, University; Humans; Immunoglobulins, Thyroid-Stimulating; Male; Natriuretic Peptide, Brain; Peptide Fragments; Risk Factors; Thyroid Hormones; Thyroxine; Triiodothyronine

2011
Exercise-induced alterations of retinal vessel diameters and cardiovascular risk reduction in obesity.
    Atherosclerosis, 2011, Volume: 216, Issue:2

    Topics: Adult; Arginine; Athletes; Cardiovascular Diseases; Enzyme-Linked Immunosorbent Assay; Exercise; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Nitric Oxide; Obesity; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; Surveys and Questionnaires

2011
Arginine/asymmetric dimethylarginine ratio and cardiovascular risk factors in patients with predialytic chronic kidney disease.
    Clinical biochemistry, 2011, Volume: 44, Issue:8-9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Cardiovascular Diseases; Female; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Middle Aged; Risk Factors; Young Adult

2011
Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:7

    Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Cardiovascular Diseases; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Female; Genotype; Hypertension; Infusion Pumps, Implantable; Male; Mice; Mice, 129 Strain; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phenotype; Risk Factors; RNA Interference; Substrate Specificity; Time Factors; Transfection

2011
Vascular function in the diagnostic categories of polycystic ovary syndrome.
    Human reproduction (Oxford, England), 2011, Volume: 26, Issue:8

    Topics: Adult; Arginine; C-Reactive Protein; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Insulin Resistance; Overweight; Phenotype; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Vascular Resistance

2011
Inflammation and asymmetric dimethylarginine for predicting death and cardiovascular events in ESRD patients.
    Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:7

    Topics: Adult; Aged; Analysis of Variance; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chi-Square Distribution; Cohort Studies; Female; Humans; Inflammation; Inflammation Mediators; Interleukin-6; Italy; Kidney Failure, Chronic; Male; Middle Aged; Prognosis; Proportional Hazards Models; Renal Dialysis; Risk Assessment; Risk Factors; Time Factors

2011
DDAH says NO to ADMA.
    Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:7

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Risk Factors; Substrate Specificity

2011
Age-related modification of antioxidant enzyme activities in relation to cardiovascular risk factors.
    European journal of clinical investigation, 2012, Volume: 42, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Apolipoproteins A; Arginine; Cardiovascular Diseases; Catalase; Enzyme-Linked Immunosorbent Assay; Female; Fetuins; Glutathione Peroxidase; Humans; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Male; Oxidation-Reduction; Oxidative Stress; Risk Factors; Statistics as Topic; Superoxide Dismutase

2012
Plasma asymmetric dimethylarginine predicts death and major adverse cardiovascular events in individuals referred for coronary angiography.
    International journal of cardiology, 2011, Dec-01, Volume: 153, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Death; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Referral and Consultation; Risk Factors

2011
Day-night variations in endothelial dysfunction markers and haemostatic factors in sleep apnoea.
    The European respiratory journal, 2012, Volume: 39, Issue:4

    Topics: Adult; Arginine; Blood Coagulation; Body Mass Index; Cardiovascular Diseases; CD40 Ligand; Circadian Rhythm; Endothelium, Vascular; Erythrocyte Count; Factor VII; Humans; Leukocyte Count; Middle Aged; Plasminogen Activator Inhibitor 1; Platelet Count; Sleep Apnea Syndromes; von Willebrand Factor; Waist Circumference

2012
Asymmetric dimethylarginine (ADMA): is really a biomarker for cardiovascular prognosis?
    International journal of cardiology, 2011, Dec-01, Volume: 153, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Coronary Angiography; Female; Humans; Male; Referral and Consultation

2011
Endothelial dysfunction and high cardiovascular risk profile in severe alcoholics improve only partially following a medium-term alcohol withdrawal.
    Alcoholism, clinical and experimental research, 2012, Volume: 36, Issue:2

    Topics: Adult; Age of Onset; Aged; Alcoholism; Arginine; Biomarkers; Blood Pressure; Brachial Artery; Cardiovascular Diseases; Confidence Intervals; Endothelium, Vascular; Female; Heart Rate; Humans; Insulin Resistance; Lipids; Logistic Models; Male; Middle Aged; Odds Ratio; Oxidative Stress; Risk Assessment; Smoking; Vasodilation

2012
Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase.
    Circulation, 2011, Dec-13, Volume: 124, Issue:24

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Dose-Response Relationship, Drug; Female; HL-60 Cells; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Animal; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxidase; Signal Transduction; Superoxides

2011
Ethnicity-specific differences in L-arginine status in South African men.
    Journal of human hypertension, 2012, Volume: 26, Issue:12

    Topics: Adult; Aged; Arginine; Black People; Cardiovascular Diseases; Cross-Sectional Studies; Humans; Hypertension; Linear Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Risk Factors; South Africa; White People

2012
Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence.
    The American journal of pathology, 2012, Volume: 180, Issue:3

    Topics: Animals; Apoptosis; Arginine; Autophagy; Azoles; Cardiovascular Diseases; Cathepsins; Cell Membrane Permeability; Cells, Cultured; Cellular Senescence; Collagen Type I; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Hydrogen Peroxide; Isoindoles; Lysosomes; Mice; Mice, Knockout; Mice, Transgenic; Organoselenium Compounds; Recombinant Proteins; Risk Factors; Sirtuin 1; Stem Cells; Stress, Physiological

2012
High tea and vegetable consumption is associated with low ADMA generation in older healthy subjects.
    Metabolism: clinical and experimental, 2012, Volume: 61, Issue:8

    Topics: Aged; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Coffee; Enzyme Inhibitors; Feeding Behavior; Female; Fruit; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Nitric Oxide Synthase; Reference Values; Risk Factors; Tea; Vegetables

2012
Asymmetric dimethylarginine: a novel cardiovascular risk factor in end-stage renal disease.
    The Journal of international medical research, 2012, Volume: 40, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Carotid Intima-Media Thickness; Demography; Female; Humans; Indonesia; Kidney Failure, Chronic; Linear Models; Male; Middle Aged; Renal Dialysis; Risk Factors

2012
The association between serum asymmetric dimethyl arginine levels and a history of gestational diabetes among healthy women.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:5

    Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Blood Glucose; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Diabetes Complications; Diabetes, Gestational; Fasting; Female; Glucose Tolerance Test; Humans; Insulin; Pregnancy; Risk Factors

2012
Interaction of the cardiovascular risk marker asymmetric dimethylarginine (ADMA) with the human cationic amino acid transporter 1 (CAT1).
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:3

    Topics: Arginine; Biological Transport; Biomarkers; Cardiovascular Diseases; Cationic Amino Acid Transporter 1; Gene Expression; HEK293 Cells; Humans; Kinesics; Metformin; Risk

2012
Elevated asymmetric dimethylarginine in young adult survivors of childhood acute lymphoblastic leukemia: a preliminary report.
    Disease markers, 2012, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Arginine; Cardiovascular Diseases; Female; Humans; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Survivors

2012
Weight loss and vascular inflammatory markers in overweight women with and without polycystic ovary syndrome.
    Reproductive biomedicine online, 2012, Volume: 25, Issue:5

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Female; Humans; Intercellular Adhesion Molecule-1; Plasminogen Activator Inhibitor 1; Polycystic Ovary Syndrome; Vascular Cell Adhesion Molecule-1; Waist Circumference; Weight Loss

2012
Exploring disease activity and cardiovascular events by raised serum asymmetric dimethyl arginine among systemic lupus erythematosus patients.
    The Egyptian journal of immunology, 2011, Volume: 18, Issue:1

    Topics: Adult; Arginine; Cardiovascular Diseases; Cholesterol; Complement C3; Cross-Sectional Studies; Egypt; Female; Humans; Logistic Models; Lupus Erythematosus, Systemic; Male; Surveys and Questionnaires

2011
Impact of ADMA, endothelial progenitor cells and traditional cardiovascular risk factors on pulse wave velocity among prediabetic individuals.
    Cardiovascular diabetology, 2012, Nov-15, Volume: 11

    Topics: Adult; Aged; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Carotid Arteries; Cholesterol, LDL; Cross-Sectional Studies; Endothelial Cells; Fasting; Female; Femoral Artery; Glucose Tolerance Test; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Prediabetic State; Predictive Value of Tests; Pulse Wave Analysis; Risk Assessment; Risk Factors; Stem Cells; Vascular Stiffness

2012
The relationship of plasma ADMA levels with cardiac functions and metabolic parameters in peritoneal dialysis patients.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:3

    Topics: Adolescent; Aged; Arginine; Aspirin; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Echocardiography; Heart; Humans; Hypertension; Middle Aged; Peritoneal Dialysis; Risk Factors

2013
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine

2013
Endothelial damage, asymmetric dimethylarginine and cardiovascular risk in end-stage renal disease.
    Blood purification, 2002, Volume: 20, Issue:5

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Kidney Failure, Chronic; Models, Cardiovascular; Risk Factors

2002
Homocysteine and ADMA--emerging risk factors for cardiovascular disease?
    Blood pressure, 2002, Volume: 11, Issue:4

    Topics: Arginine; Cardiovascular Diseases; Homocysteine; Humans; Predictive Value of Tests; Risk Factors

2002
High-performance liquid chromatographic assay of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine in human plasma by derivatization with naphthalene-2,3-dicarboxaldehyde.
    Analytical biochemistry, 2003, Jul-01, Volume: 318, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Naphthalenes; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism

2003
When the endothelium cannot say 'NO' anymore. ADMA, an endogenous inhibitor of NO synthase, promotes cardiovascular disease.
    European heart journal, 2003, Volume: 24, Issue:21

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase

2003
Plasma concentration of coupling factor 6 and cardiovascular events in patients with end-stage renal disease.
    Kidney international, 2003, Volume: 64, Issue:6

    Topics: Aged; Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Mitochondrial Proton-Translocating ATPases; Oxidative Phosphorylation Coupling Factors; Radioimmunoassay; Risk Factors

2003
Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase.
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Homeostasis; Humans; Hyperhomocysteinemia; Hyperlipidemias; Nitric Oxide Synthase; Vasodilation

2003
Cytomegalovirus infection impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine in transplant arteriosclerosis.
    Circulation, 2004, Feb-03, Volume: 109, Issue:4

    Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Cells, Cultured; Coronary Angiography; Coronary Artery Disease; Cyclic GMP; Cytomegalovirus Infections; Endothelium, Vascular; Female; Heart Transplantation; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Risk Factors; Signal Transduction

2004
Prognostic value of combined use of biomarkers of inflammation, endothelial dysfunction, and myocardiopathy in patients with ESRD.
    Kidney international, 2005, Volume: 67, Issue:6

    Topics: Adult; Aged; Arginine; Arteriosclerosis; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Endothelium, Vascular; Female; Heart Failure; Humans; Kidney Failure, Chronic; Male; Middle Aged; Natriuretic Peptide, Brain; Prognosis

2005
Asymmetric dimethyl arginine levels correlate with cardiovascular risk factors in patients with erectile dysfunction.
    Atherosclerosis, 2006, Volume: 185, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Arginine; Blood Pressure; C-Reactive Protein; Cardiovascular Diseases; Cholesterol, LDL; E-Selectin; Enzyme Inhibitors; Erectile Dysfunction; Humans; Male; Middle Aged; Nitric Oxide Synthase; Piperazines; Purines; Risk Factors; Sildenafil Citrate; Sulfones

2006
The effects of thyroxine replacement on the levels of serum asymmetric dimethylarginine (ADMA) and other biochemical cardiovascular risk markers in patients with subclinical hypothyroidism.
    Clinical endocrinology, 2005, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Enzyme Inhibitors; Female; Homocysteine; Hormone Replacement Therapy; Humans; Hypothyroidism; Lipoproteins, HDL; Lipoproteins, LDL; Middle Aged; Nitric Oxide; Risk Factors; Thyrotropin; Thyroxine; Triiodothyronine

2005
Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study.
    Circulation research, 2005, Sep-02, Volume: 97, Issue:5

    Topics: Adult; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Coronary Disease; Creatinine; Female; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Prospective Studies; Risk Factors

2005
Raised plasma levels of asymmetric dimethylarginine are associated with cardiovascular events, disease activity, and organ damage in patients with systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2005, Volume: 64, Issue:9

    Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Female; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Nitric Oxide Synthase; Regression Analysis; Risk Factors; Severity of Illness Index

2005
The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease.
    Journal of hypertension, 2005, Volume: 23, Issue:10

    Topics: Adult; Aged; Amino Acid Substitution; Analysis of Variance; Arginine; Aspartic Acid; Cardiovascular Diseases; Female; Gene Frequency; Genotype; Glutamic Acid; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide Synthase; Polymorphism, Genetic; Regression Analysis; Survival Rate

2005
Determination of a reference value for N(G), N(G)-dimethyl-L-arginine in 500 subjects.
    European journal of clinical investigation, 2005, Volume: 35, Issue:10

    Topics: Adult; Aged; Aging; Arginine; Biomarkers; Cardiovascular Diseases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Reference Values; Sensitivity and Specificity; Sex Characteristics

2005
Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA.
    PLoS medicine, 2005, Volume: 2, Issue:10

    Topics: Arginine; Atherosclerosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Cardiovascular Diseases; Cell Culture Techniques; Endothelial Cells; Gene Expression Profiling; Gene Expression Regulation; Humans; Hypertension, Pulmonary; Oligonucleotide Array Sequence Analysis; Protein-Arginine N-Methyltransferases; Smad5 Protein; Transforming Growth Factor beta

2005
ADMA, endothelial progenitor cells, and cardiovascular risk.
    Circulation research, 2005, Oct-14, Volume: 97, Issue:8

    Topics: Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Risk Factors; Stem Cells

2005
The determinants of endothelial dysfunction in CKD: oxidative stress and asymmetric dimethylarginine.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Adult; Arginine; Brachial Artery; Cardiovascular Diseases; Chronic Disease; Copper; Endothelium, Vascular; Erythrocytes; Female; Glomerular Filtration Rate; Glutathione Peroxidase; Humans; Kidney Diseases; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Selenium; Severity of Illness Index; Superoxide Dismutase; Vasodilation; Zinc

2006
Endurance training reduces circulating asymmetric dimethylarginine and myeloperoxidase levels in persons at risk of coronary events.
    Thrombosis and haemostasis, 2005, Volume: 94, Issue:6

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cyclic GMP; Exercise; Female; Humans; Male; Middle Aged; Peroxidase; Risk Factors

2005
Evidence for associations between common polymorphisms of estrogen receptor beta gene with homocysteine and nitric oxide.
    Climacteric : the journal of the International Menopause Society, 2006, Volume: 9, Issue:3

    Topics: Aged; Arginine; Body Mass Index; Cardiovascular Diseases; Cross-Sectional Studies; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Folic Acid; Genetic Variation; Genotype; Homocysteine; Humans; Linkage Disequilibrium; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Polymorphism, Single Nucleotide; Postmenopause; Risk Factors; Vitamin B 12

2006
Asymmetric dimethylarginine predicts major adverse cardiovascular events in patients with advanced peripheral artery disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:11

    Topics: Aged; Arginine; Arteries; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cohort Studies; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Osmolar Concentration; Peripheral Vascular Diseases; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Severity of Illness Index

2006
Association of homocysteine and asymmetric dimethylarginine with atherosclerosis and cardiovascular events in maintenance hemodialysis patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:5

    Topics: Arginine; Atherosclerosis; Cardiovascular Diseases; Comorbidity; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nitric Oxide Synthase; Proportional Hazards Models; Regression Analysis; Renal Dialysis; Risk Factors

2006
Asymmetrical dimethylarginine independently predicts total and cardiovascular mortality in individuals with angiographic coronary artery disease (the Ludwigshafen Risk and Cardiovascular Health study).
    Clinical chemistry, 2007, Volume: 53, Issue:2

    Topics: Analysis of Variance; Arginine; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Coronary Disease; Female; Humans; Male; Middle Aged; Mortality; Predictive Value of Tests; Regression Analysis; Risk Factors

2007
Should we measure asymmetric dimethylarginine in patients with coronary artery disease?
    Clinical chemistry, 2007, Volume: 53, Issue:2

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Coronary Artery Disease; Humans; Mortality; Predictive Value of Tests; Risk Factors

2007
ADMA is independently related to flow-mediated vasodilation in subjects at low cardiovascular risk.
    European journal of clinical investigation, 2007, Volume: 37, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Female; Humans; Insulin; Male; Middle Aged; Risk Factors; Vasodilation

2007
A new perspective for the treatment of renal diseases?
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:5

    Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Chronic Disease; Humans; Kidney Diseases; Nitric Oxide Synthase; Risk Factors

2007
Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes.
    Diabetes care, 2007, Volume: 30, Issue:7

    Topics: Aged; Arginine; C-Reactive Protein; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Assessment

2007
Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery.
    Critical care medicine, 2007, Volume: 35, Issue:8

    Topics: Arginine; Biomarkers; Cardiovascular Diseases; Female; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Nitric Oxide Synthase; Perioperative Care; Postoperative Complications; Prospective Studies; Risk Assessment; Surgical Procedures, Operative

2007
Brachial artery flow-mediated dilation and asymmetrical dimethylarginine in the cardiovascular risk in young Finns study.
    Circulation, 2007, Sep-18, Volume: 116, Issue:12

    Topics: Adult; Arginine; Biomarkers; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; Endothelium, Vascular; Female; Finland; Follow-Up Studies; Hemorheology; Humans; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Risk; Sampling Studies; Vasodilation

2007
Unchanged asymmetric dimethylarginine levels in non-diabetic, premenopausal obese women who have common risk factors for cardiovascular disease.
    Endocrine, 2007, Volume: 31, Issue:2

    Topics: Adult; Arginine; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Insulin Resistance; Middle Aged; Obesity; Overweight; Premenopause; Regression Analysis; Risk Factors

2007
Oxidative stress in cardiovascular disease: successful translation from bench to bedside?
    Circulation, 2007, Sep-18, Volume: 116, Issue:12

    Topics: Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Hemorheology; Humans; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Risk; Thrombosis; Vasodilation

2007
Asymmetric dimethylarginine plasma concentrations and L-arginine/asymmetric dimethylarginine ratio in patients with slow coronary flow.
    Coronary artery disease, 2007, Volume: 18, Issue:7

    Topics: Adult; Aged; Arginine; Blood Flow Velocity; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Coronary Angiography; Coronary Circulation; Exercise Test; Female; Humans; Male; Middle Aged; Myocardium; Nitric Oxide; Sensitivity and Specificity; Thrombolytic Therapy

2007
Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation.
    Stroke, 2008, Volume: 39, Issue:1

    Topics: Acetylcholine; Amidohydrolases; Animals; Aorta; Arginine; Arterioles; Cardiovascular Diseases; Carotid Arteries; Cerebrovascular Circulation; Endothelium, Vascular; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Vasodilator Agents

2008
Asymmetric dimethylarginine and impaired cardiovascular healing.
    Journal of thrombosis and thrombolysis, 2009, Volume: 27, Issue:2

    Topics: Apoptosis; Arginine; Cardiovascular Diseases; Humans; Kidney Diseases; Myocardial Ischemia; Nitric Oxide; Prognosis; Regeneration; Stem Cells; Treatment Outcome

2009
Effects of moderate hyperhomocysteinaemia induced by 4 weeks methionine-enriched diet on metabolite profile and mesenteric artery function in rats.
    The British journal of nutrition, 2008, Volume: 99, Issue:5

    Topics: Animals; Arginine; Biomarkers; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Diet; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methionine; Rats; Rats, Wistar; Vasodilation

2008
The homocysteine paradox.
    Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:6

    Topics: Animals; Arginine; Cardiovascular Diseases; Cystatin C; Cystatins; Disease Models, Animal; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Risk Factors; Vitamin B 12; Vitamin B 6

2008
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor.
    JAMA, 2002, Mar-20, Volume: 287, Issue:11

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Cross-Sectional Studies; Enzyme Inhibitors; Female; Humans; Hypertension; Hypoglycemic Agents; Lipoproteins; Male; Metabolic Diseases; Metabolic Syndrome; Middle Aged; Nitric Oxide Synthase; Regression Analysis; Risk Factors; Rosiglitazone; Thiazoles; Thiazolidinediones; Vasodilator Agents

2002
Insulin resistance, ADMA levels, and cardiovascular disease.
    JAMA, 2002, Mar-20, Volume: 287, Issue:11

    Topics: Arginine; Cardiovascular Diseases; Enzyme Inhibitors; Humans; Insulin Resistance; Metabolic Syndrome; Nitric Oxide Synthase; Risk Factors

2002