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n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and Iron Overload

n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid has been researched along with Iron Overload in 6 studies

*Iron Overload: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989) [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Knutson, M; Lavin, SR; Livingston, S; Sullivan, KE; Valdes, EV; Warren, LK1
Hider, RC; Tilbrook, GS1
Bergeron, RJ; Brittenham, GM; Wiegand, J3
Hershko, C; Konijn, AM; Link, G1

Reviews

2 review(s) available for n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and Iron Overload

ArticleYear
Iron chelators for clinical use.
    Metal ions in biological systems, 1998, Volume: 35

    Topics: Biological Transport; Deferoxamine; Drug Delivery Systems; Edetic Acid; Ferric Compounds; Free Radical Scavengers; Humans; Iron; Iron Chelating Agents; Iron Overload; Ligands; Molecular Weight; Oxidation-Reduction; Pentetic Acid; Razoxane; Solubility; Structure-Activity Relationship; Tissue Distribution

1998
Iron chelators for thalassaemia.
    British journal of haematology, 1998, Volume: 101, Issue:3

    Topics: Administration, Oral; Aza Compounds; Chelating Agents; Deferiprone; Deferoxamine; Edetic Acid; Humans; Iron; Iron Chelating Agents; Iron Overload; Long-Term Care; Pyridones; Thalassemia

1998

Trials

1 trial(s) available for n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and Iron Overload

ArticleYear
Safety and efficacy of a novel iron chelator (HBED; (N,N'-Di(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid)) in equine (Equus caballus) as a model for black rhinoceros (Diceros bicornis).
    Journal of animal physiology and animal nutrition, 2022, Volume: 106, Issue:5

    Topics: Acetates; Animals; Edetic Acid; Ethylenediamines; Horse Diseases; Horses; Iron; Iron Chelating Agents; Iron Overload; Perissodactyla

2022

Other Studies

3 other study(ies) available for n,n'-bis(2-hydroxybenzyl)ethylenediamine-n,n'-diacetic acid and Iron Overload

ArticleYear
HBED: A potential alternative to deferoxamine for iron-chelating therapy.
    Blood, 1998, Feb-15, Volume: 91, Issue:4

    Topics: Animals; Antidotes; Chelating Agents; Deferoxamine; Edetic Acid; Haplorhini; Iron Overload; Male; Rats; Rats, Sprague-Dawley; Transfusion Reaction

1998
HBED: the continuing development of a potential alternative to deferoxamine for iron-chelating therapy.
    Blood, 1999, Jan-01, Volume: 93, Issue:1

    Topics: Administration, Oral; Animals; Cebus; Deferoxamine; Edetic Acid; Injections, Intravenous; Injections, Subcutaneous; Iron; Iron Chelating Agents; Iron Overload; Iron-Dextran Complex; Male; Rats; Rats, Sprague-Dawley

1999
HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning.
    Blood, 2002, Apr-15, Volume: 99, Issue:8

    Topics: Acute Disease; Animals; Blood Pressure; Cebus; Chronic Disease; Deferoxamine; Disease Models, Animal; Dogs; Drug Administration Routes; Drug Evaluation, Preclinical; Edetic Acid; Heart Rate; Iron; Iron Chelating Agents; Iron Overload; Male; Poisoning; Rats; Rats, Sprague-Dawley; Therapeutic Equivalency

2002