Page last updated: 2024-08-25

n-methylscopolamine and Muscle Contraction

n-methylscopolamine has been researched along with Muscle Contraction in 43 studies

*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (20.93)	18.7374
1990's	23 (53.49)	18.2507
2000's	9 (20.93)	29.6817
2010's	2 (4.65)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Go, ML; Sim, MK; Xu, R	1
Bellucci, C; Buccioni, M; Dei, S; Ferraroni, M; Guandalini, L; Manetti, D; Martini, E; Marucci, G; Matucci, R; Nesi, M; Romanelli, MN; Scapecchi, S; Teodori, E	1
Barocelli, E; Bertoni, S; Bonifazi, A; Camalli, M; Campi, G; Del Bello, F; Giannella, M; Matucci, R; Nesi, M; Piergentili, A; Pigini, M; Quaglia, W	1
Anisuzzaman, AS; Ikeda, T; Itoh, H; Koshiji, T; Muramatsu, I; Nishimune, A; Sasaki, M; Uwada, J; Yoshiki, H	1
Emala, CW; Jooste, EH; Sharma, A; Zhang, Y	1
Braeter, M; Hakenberg, OW; Kelly, LU; Ravens, U; Waelbroeck, M; Weiss, A; Wuest, M	1
Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H	1
Akiho, H; Al-Kaabi, A; Blennerhassett, P; Collins, SM; Deng, Y; Khan, WI	1
Dakshinamurti, S; Dueck, G; Gerthoffer, WT; Gosens, R; Halayko, AJ; Hinton, M; McNeill, KD; Mutawe, MM; Paulson, A; Stelmack, GL; Thliveris, JA; Unruh, H; Zaagsma, J	1
Akino, H; Anisuzzaman, AS; Morishima, S; Muramatsu, I; Sathi, ZS; Suzuki, F; Tanaka, T; Yokoyama, O; Yoshiki, H	1
Luthin, GR; Ruggieri, MR; Wang, P	1
Bali, JP; Cuq, P; Magous, R	1
Ehlert, FJ; Thomas, EA	1
Adem, A; Hellman, U; Jolkkonen, M; Karlsson, E; Kumlin, E; Satyapan, N; Wernstedt, C	1
Greten, H; Mirau, S; Raedler, A; Sievers, J; von Schrenck, T	1
Segerberg, MA; Stretton, AO	1
Bymaster, FP; Mitch, CH; Olesen, PH; Sauerberg, P; Shannon, HE; Sheardown, MJ; Suzdak, PD; Swedberg, MD; Ward, JS	1
Kim, CY; Sohn, UD	1
Allescher, HD; Kurjak, M; Sattler, D; Schusdziarra, V	1
Chien, CS; Chiu, CT; Lin, CC; Pan, SL; Shyr, MH; Tan, PP; Wang, CC; Yang, CM	1
Akici, A; Christopoulos, A; El-Fakahany, EE; Iskender, E; Karaalp, A; Oktay, S	1
Ehlert, FJ; Lambrecht, G; Sawyer, GW	1
Bali, JP; Cros, G; Serrano, JJ; Soulié, ML	1
Baker, R; Davis, J; Freedman, SB; Hargreaves, R; Hoogsteen, K; Patel, S; Showell, GA; Snow, RJ	1
Baumgold, J; Boyd, VL; Chiang, PK; Gordon, RK; Leader, H; Newman, AH; Smejkal, RM	1
Pechnick, RN; Vargas, HM	1
Hasler, WL; Heldsinger, A; Owyang, C	1
Brunner, F; Kühberger, E; Kukovetz, WR; Schloos, J	1
Endou, M	1
Baumann, M; Fleshman, JW; Kodner, IJ; Lepor, H; Rigaud, G; Shapiro, E	1
Candell, LM; Ehlert, FJ; Tran, LL; Yun, SH	1
Caldirola, P; Hacksell, U; Lundkvist, JR; Ringdahl, B; Vargas, HM	1
Doods, HN; Entzeroth, M; Mayer, N	1
Aronstam, RS; Carrier, GO	1
Breuer, E; Chiang, PK; Gordon, RK; Padilla, FN; Smejkal, RM	1
Hacksell, U; Lundkvist, JR; Ringdahl, B	1
Cornett, CM; Eglen, RM; Kunysz, EA; Michel, AD; Whiting, RL	1
Brown, DA; Marrion, NV; Marsh, SJ; Smart, TG	1
Bali, JP; Magous, R; Moummi, C; Strosberg, D	1
Hsu, CT; Hyman, PE; Jing, J; Snape, WJ; Tomomasa, T	1
Bieger, D; Triggle, C	1
Cuevas, N; Miranda, HF; Silva, WI; Wolstenholme, WW	1
Chiang, PK; Gordon, RK; Witkin, JM	1

Other Studies

43 other study(ies) available for n-methylscopolamine and Muscle Contraction

Article	Year
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17 Topics: Animals; Aorta; Binding, Competitive; Drug Design; Escape Reaction; In Vitro Techniques; Male; Maze Learning; Mice; Models, Molecular; Molecular Structure; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylscopolamine; Nuclear Magnetic Resonance, Biomolecular; Piperidines; Pirenzepine; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Structure-Activity Relationship; Tropanes	1998
Synthesis, affinity profile, and functional activity of muscarinic antagonists with a 1-methyl-2-(2,2-alkylaryl-1,3-oxathiolan-5-yl)pyrrolidine structure. Journal of medicinal chemistry, 2007, Mar-22, Volume: 50, Issue:6 Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Pyrrolidines; Rabbits; Radioligand Assay; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Vas Deferens	2007
1,4-dioxane, a suitable scaffold for the development of novel M₃ muscarinic receptor antagonists. Journal of medicinal chemistry, 2012, Feb-23, Volume: 55, Issue:4 Topics: Animals; Blood Pressure; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Dioxanes; Guinea Pigs; Heart Rate; Humans; Molecular Structure; Muscle Contraction; Muscle, Smooth; Rats; Receptor, Muscarinic M3; Stereoisomerism; Structure-Activity Relationship; Urinary Bladder; Urination	2012
Regional quantification of muscarinic acetylcholine receptors and β-adrenoceptors in human airways. British journal of pharmacology, 2012, Volume: 166, Issue:6 Topics: Aged; Carbachol; Female; Humans; In Vitro Techniques; Isoproterenol; Ligands; Lung; Male; Middle Aged; Muscle Contraction; N-Methylscopolamine; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Muscarinic	2012
Rapacuronium augments acetylcholine-induced bronchoconstriction via positive allosteric interactions at the M3 muscarinic receptor. Anesthesiology, 2005, Volume: 103, Issue:6 Topics: Acetylcholine; Animals; Bronchoconstriction; Drug Synergism; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Kinetics; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Neuromuscular Nondepolarizing Agents; Parasympatholytics; Radioligand Assay; Receptor, Muscarinic M3; Stereoisomerism; Trachea; Vecuronium Bromide	2005
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction. Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 374, Issue:2 Topics: Animals; Benzilates; Binding, Competitive; Calcium; Carbachol; Cell Line; Cells, Cultured; CHO Cells; Cholinergic Antagonists; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electric Stimulation; Epithelial Cells; Humans; Molecular Structure; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Potassium Chloride; Receptors, Muscarinic; Urinary Bladder	2006
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1 Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination	2007
Cytokine modulation of muscarinic receptors in the murine intestine. American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:1 Topics: Animals; Carbachol; Interferon gamma Receptor; Interferon-gamma; Jejunum; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; N-Methylscopolamine; Receptors, Interferon; Receptors, Muscarinic; Receptors, Transforming Growth Factor beta; STAT6 Transcription Factor; Transforming Growth Factor beta; Trichinella spiralis; Trichinellosis	2007
Caveolae facilitate muscarinic receptor-mediated intracellular Ca2+ mobilization and contraction in airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:6 Topics: Acetylcholine; Animals; beta-Cyclodextrins; Calcium Signaling; Caveolae; Caveolin 1; Cells, Cultured; Cytosol; Dogs; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Intracellular Space; Muscle Cells; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Protein Structure, Tertiary; Receptor, Muscarinic M3; Respiratory System; RNA, Small Interfering; Trachea; Tritium	2007
Assessment of muscarinic receptor subtypes in human and rat lower urinary tract by tissue segment binding assay. Journal of pharmacological sciences, 2008, Volume: 106, Issue:2 Topics: Aged; Animals; Carbachol; Cell Membrane; Female; Humans; In Vitro Techniques; Male; Middle Aged; Mucous Membrane; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Prostate; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Urinary Bladder	2008
Muscarinic acetylcholine receptor subtypes mediating urinary bladder contractility and coupling to GTP binding proteins. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2 Topics: Animals; GTP-Binding Proteins; Humans; Muscarinic Agonists; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Precipitin Tests; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Species Specificity; Urinary Bladder	1995
Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1 Topics: Adenylyl Cyclases; Animals; Cecum; Cyclic AMP; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1994
Pertussis toxin blocks M2 muscarinic receptor-mediated effects on contraction and cyclic AMP in the guinea pig ileum, but not M3-mediated contractions and phosphoinositide hydrolysis. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2 Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Cyclic AMP; Guanosine Triphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Signal Transduction; Virulence Factors, Bordetella	1994
Protein toxins that bind to muscarinic acetylcholine receptors. Annals of the New York Academy of Sciences, 1994, Mar-09, Volume: 710 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Consensus Sequence; Elapid Venoms; Elapidae; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Protein Binding; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Sequence Homology, Amino Acid; Swine; Synaptosomes	1994
Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle. Gastroenterology, 1993, Volume: 105, Issue:5 Topics: Animals; Autoradiography; Carbachol; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tetrodotoxin	1993
Actions of cholinergic drugs in the nematode Ascaris suum. Complex pharmacology of muscle and motorneurons. The Journal of general physiology, 1993, Volume: 101, Issue:2 Topics: Acetylcholine; Acetylcholinesterase; Animals; Ascaris suum; Choline; Electrophysiology; In Vitro Techniques; Membrane Potentials; Microelectrodes; Motor Neurons; Muscle Contraction; Muscles; N-Methylscopolamine; Neuromuscular Junction; Nicotine; Parasympatholytics; Parasympathomimetics; Pilocarpine; Scopolamine Derivatives; Synapses	1993
M1 receptor agonist activity is not a requirement for muscarinic antinociception. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:2 Topics: Analgesics; Animals; Atrial Function; Cell Line; Cricetinae; Guinea Pigs; Heart Atria; Humans; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Male; Mice; Muscarinic Agonists; Muscle Contraction; N-Methylscopolamine; Naltrexone; Rabbits; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Transfection; Vas Deferens	1997
Suppression of the rat micturition reflex by imipramine. Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1 Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Antidepressive Agents, Tricyclic; Atropine; Cholinergic Agents; Dose-Response Relationship, Drug; Drug Interactions; Enuresis; Enzyme Inhibitors; Female; Fenclonine; Hemicholinium 3; Imipramine; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Methyltyrosines; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Sprague-Dawley; Scopolamine Derivatives; Serotonin Agents; Urination	1997
Characterization of prejunctional and postjunctional muscarinic receptors of the ascending reflex contraction in rat ileum. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2 Topics: Animals; Binding Sites; Binding, Competitive; Electric Stimulation; Ileum; In Vitro Techniques; Intercellular Junctions; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Radioligand Assay; Rats; Rats, Wistar; Receptors, Muscarinic; Reflex; Subcellular Fractions; Synaptosomes	1999
Mechanisms underlying the inhibitory effect of propofol on the contraction of canine airway smooth muscle. Anesthesiology, 1999, Volume: 91, Issue:3 Topics: Anesthetics, Intravenous; Animals; Calcium; Carbachol; Dogs; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; N-Methylscopolamine; Propofol; Trachea	1999
Further evidence for the heterogeneity of functional muscarinic receptors in guinea pig gallbladder. European journal of pharmacology, 2000, Jan-24, Volume: 388, Issue:1 Topics: Animals; Calcium; Cell Membrane; CHO Cells; Cricetinae; Female; Gallbladder; Guinea Pigs; Humans; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Radioligand Assay; Receptors, Muscarinic; Urinary Bladder	2000
Functional role of muscarinic M(2) receptors in alpha,beta-methylene ATP induced, neurogenic contractions in guinea-pig ileum. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: Adenosine Triphosphate; Animals; Diphenylacetic Acids; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Contraction; N-Methylscopolamine; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tetrodotoxin; Virulence Factors, Bordetella	2000
Impairment of contractile response to carbachol and muscarinic receptor coupling in gastric antral smooth muscle cells isolated from diabetic streptozotocin-treated rats and db/db mice. Molecular and cellular biochemistry, 1992, Feb-12, Volume: 109, Issue:2 Topics: Animals; Carbachol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Erythromycin; Female; Guanosine 5'-O-(3-Thiotriphosphate); Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pyloric Antrum; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Streptozocin	1992
Synthesis and in vitro biological profile of all four isomers of the potent muscarinic agonist 3-(3-methyl-1,2,4-oxadiazol-5-yl)-1-azabicyclo[2.2.1]heptane. Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5 Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Electrophysiology; Ganglia, Sympathetic; Guinea Pigs; Heart Rate; Ileum; Male; Molecular Conformation; Molecular Structure; Muscle Contraction; Myenteric Plexus; N-Methylscopolamine; Oxadiazoles; Parasympathomimetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction	1992
Muscarinic receptor subtype specificity of (N,N-dialkylamino)alkyl 2-cyclohexyl-2-phenylpropionates: cylexphenes (cyclohexyl-substituted aprophen analogues). Journal of medicinal chemistry, 1992, Apr-03, Volume: 35, Issue:7 Topics: Acetylcholine; alpha-Amylases; Animals; Binding, Competitive; Carbachol; Cyclohexanes; Guinea Pigs; Ileum; Male; Molecular Structure; Muscarine; Muscle Contraction; N-Methylscopolamine; Pancreas; Phenylpropionates; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Transfection	1992
Binding affinity and antimuscarinic activity of sigma and phencyclidine receptor ligands. European journal of pharmacology, 1991, Mar-19, Volume: 195, Issue:1 Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Dioxolanes; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pentazocine; Phosphatidylinositols; Piperidines; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Phencyclidine; Scopolamine Derivatives	1991
Cisapride acts on muscarinic (glandular M2) receptors to induce contraction of isolated gastric myocytes: mediation via a calcium-phosphoinositide pathway. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3 Topics: Adenylyl Cyclases; Animals; Calcium; Cells, Cultured; Cisapride; Gastric Mucosa; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phosphatidylinositols; Piperidines; Receptors, Muscarinic; Receptors, Serotonin; Scopolamine Derivatives; Second Messenger Systems; Serotonin Antagonists; Signal Transduction; Stomach; Tritium	1991
Characterization of muscarinic receptors of bovine coronary artery by functional and radioligand binding studies. European journal of pharmacology, 1991, Apr-24, Volume: 196, Issue:3 Topics: Acetylcholine; Animals; Binding, Competitive; Cattle; Coronary Vessels; Endothelium, Vascular; Female; Kinetics; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; N-Methylscopolamine; Parasympatholytics; Physostigmine; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Tritium	1991
[Pharmacological analysis of drug interactions of disopyramide and its congeners with peripheral muscarinic acetylcholine receptors]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1991, Volume: 66, Issue:5 Topics: Animals; Binding, Competitive; Carbachol; Disopyramide; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Myocardial Contraction; N-Methylscopolamine; Piperidines; Propylamines; Pyridines; Receptors, Muscarinic; Scopolamine Derivatives	1991
Muscarinic cholinergic and alpha 2-adrenergic receptors in the epithelium and muscularis of the human ileum. Surgery, 1990, Volume: 107, Issue:4 Topics: Epithelium; Humans; Ileum; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Potassium Chloride; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine Derivatives; Tritium; Yohimbine	1990
Differential coupling of subtypes of the muscarinic receptor to adenylate cyclase and phosphoinositide hydrolysis in the longitudinal muscle of the rat ileum. Molecular pharmacology, 1990, Volume: 38, Issue:5 Topics: Adenylyl Cyclases; Animals; Binding Sites; Binding, Competitive; Diamines; Hydrolysis; Ileum; In Vitro Techniques; Male; Mathematics; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phosphatidylinositols; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Resolved pyrrolidine, piperidine, and perhydroazepine analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide. Journal of medicinal chemistry, 1990, Volume: 33, Issue:12 Topics: Animals; Azepines; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Magnetic Resonance Spectroscopy; Male; Molecular Conformation; Molecular Structure; Muscle Contraction; N-Methylscopolamine; Parasympathomimetics; Piperidines; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism	1990
Characterization of porcine coronary muscarinic receptors. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:5 Topics: Animals; Arteries; Coronary Vessels; Dose-Response Relationship, Drug; Kinetics; Membranes; Muscarine; Muscle Contraction; Muscle, Smooth, Vascular; N-Methylscopolamine; Parasympatholytics; Potassium Chloride; Receptors, Muscarinic; Scopolamine Derivatives; Swine; Tritium	1990
Increased muscarinic responsiveness and decreased muscarinic receptor content in ileal smooth muscle in diabetes. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2 Topics: Acetylcholinesterase; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Ileum; Injections, Intravenous; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1990
Distance geometry of alpha-substituted 2,2-diphenylpropionate antimuscarinics. Molecular pharmacology, 1989, Volume: 36, Issue:5 Topics: alpha-Amylases; Animals; Biological Assay; Computer Simulation; Diphenylacetic Acids; Guinea Pigs; In Vitro Techniques; Molecular Conformation; Muscle Contraction; N-Methylscopolamine; Parasympatholytics; Phenylpropionates; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship	1989
Conformationally restricted analogues of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide. Journal of medicinal chemistry, 1989, Volume: 32, Issue:4 Topics: Animals; Biological Assay; Cerebral Cortex; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Mice; Molecular Conformation; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Pyrrolidines; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship; Tremor	1989
The interaction of hexamethonium with muscarinic receptor subtypes in vitro. British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: Animals; Carbachol; Diamines; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; N-Methylscopolamine; Pirenzepine; Potassium Chloride; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland	1989
Muscarinic suppression of the M-current in the rat sympathetic ganglion is mediated by receptors of the M1-subtype. British journal of pharmacology, 1989, Volume: 98, Issue:2 Topics: Animals; Calcium; Gallamine Triethiodide; Ganglia, Spinal; Ganglia, Sympathetic; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Piperidines; Pirenzepine; Potassium Channels; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives	1989
Muscarinic receptors in isolated smooth muscle cells from gastric antrum. Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7 Topics: Acetylcholine; Animals; Antibodies, Monoclonal; Atropine; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pyloric Antrum; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives	1988
Development of the muscarinic receptor in rabbit gastric smooth muscle. The American journal of physiology, 1988, Volume: 254, Issue:5 Pt 1 Topics: Animals; Animals, Newborn; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Kinetics; Muscle Contraction; Muscle Development; Muscle, Smooth; N-Methylscopolamine; Phenethylamines; Piperidines; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Stomach	1988
Pharmacological properties of mechanical responses of the rat oesophageal muscularis mucosae to vagal and field stimulation. British journal of pharmacology, 1985, Volume: 84, Issue:1 Topics: Animals; Dioxolanes; Electric Stimulation; Esophagus; Hexamethonium Compounds; In Vitro Techniques; Ketanserin; Male; Morphine; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Naloxone; Piperidines; Rats; Rats, Inbred Strains; Scopolamine Derivatives; Serotonin; Tetrodotoxin; Tubocurarine; Vagus Nerve	1985
Selective antagonism by pirenzepine and N-methyl-scopolamine on muscarinic receptor subtypes of the rat vas deferens. General pharmacology, 1988, Volume: 19, Issue:3 Topics: Animals; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Vas Deferens	1988
Comparison of in vitro actions with behavioral effects of antimuscarinic agents. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3 Topics: alpha-Amylases; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Structure-Activity Relationship	1987