n-methylaspartate has been researched along with Substance Withdrawal Syndrome in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.44) | 18.7374 |
| 1990's | 23 (51.11) | 18.2507 |
| 2000's | 16 (35.56) | 29.6817 |
| 2010's | 4 (8.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barron, S; Carter, M; Fields, L; Littleton, JM; Lutz, JA | 1 |
| Butler, TR; Prendergast, MA; Smith, KJ | 1 |
| Eastes, LE | 1 |
| Ali, C; Docagne, F; Fernandez-Ruiz, J; Ramos, JA; Roussel, BD; Rubio, M; Villain, H; Vivien, D | 1 |
| King, MA; Nitsche, JF; Pasternak, GW; Pintar, JE; Schuller, AG; Zengh, M | 1 |
| Kendig, JJ; Li, HF | 1 |
| Blanchard, JA; Foster, TC; Gibson, DA; Harris, BR; Hart, SR; Holley, RC; Littleton, JM; Pedigo, NW; Prendergast, MA; Scotland, RL | 1 |
| Cory-Slechta, DA; Reeves, R; Thiruchelvam, M | 1 |
| Faleiro, LJ; Jones, S; Kauer, JA | 1 |
| Bossert, JM; Dempsey, J; Hope, BT; Liu, SY; Lu, L; Shaham, Y | 1 |
| Abou Zeit-Har, MS; Afify, EA; Daabees, TT; Gabra, BH | 1 |
| Fujio, M; Kaneko, S; Minami, M; Nakagawa, T; Satoh, M; Suzuki, Y; Yamamoto, R | 1 |
| Enomoto, T; Furukawa, H; Hotta, K; Kim, HC; Mouri, A; Murai, R; Nabeshima, T; Nitta, A; Noda, Y; Shin, EJ; Wang, D | 1 |
| Badaras, R; Ivaskevicius, J; Jovaisa, T; Laurinenas, G; Sipylaite, J; Vosylius, S | 1 |
| Blanchard, J; Chambers, ER; Holley, RC; Littleton, JM; Prendergast, MA; Wilkins, LH | 1 |
| Belknap, JK; Carter, LA; Crabbe, JC; Janowsky, A | 1 |
| Little, HJ; Molleman, A | 1 |
| Little, HJ; Rabbani, M; Wright, EJ | 1 |
| Le, F; Matsumoto, I; Shanley, BC; Wilce, PA | 1 |
| Davidson, M; Shanley, B; Wilce, P | 1 |
| Kreeger, JS; Larson, AA | 1 |
| De Witte, P; Deuceuninck, D; Lamblin, F | 1 |
| Butterworth, AR; Little, HJ; Rabbani, M; Wright, J; Zhou, Q | 1 |
| Hoffman, PL; Tabakoff, B | 1 |
| Crabbe, JC; Kosobud, AE | 1 |
| Belozertseva, I; Bespalov, A; Zvartau, E | 1 |
| Kosten, TA; Muly, SM; Shoemaker, WJ | 1 |
| Little, HJ; Wilson, J | 1 |
| Fartacek, R; Geretsegger, C | 1 |
| Elsworth, JD; Punch, LJ; Taylor, JR | 1 |
| Bailey, CP; Little, HJ; Manley, SJ; Molleman, A; Watson, WP; Wonnacott, S | 1 |
| Crews, FT; Knapp, DJ | 1 |
| Carboni, S; Fadda, F; Rossetti, ZL | 1 |
| Ho, IK; Jang, C; Park, Y; Rockhold, RW | 1 |
| Aghajanian, GK; Jolas, T; Nestler, EJ | 1 |
| Morrisett, RA; Thomas, MP | 1 |
| Ho, IK; Oh, S; Tokuyama, S; Yamamoto, T; Zhu, H | 1 |
| Schoffelmeer, AN; Vanderschuren, LJ; Wardeh, G | 1 |
| László, L; Nagy, J | 1 |
| Engberg, G; Hajós, M | 1 |
| Grant, KA; Rogawski, MA; Snell, LD; Tabakoff, B; Thurkauf, A | 1 |
| Rasmussen, K | 1 |
| Antonelli, T; Beani, L; Bianchi, C; Morari, M; Tanganelli, S | 1 |
| McCaslin, PP; Morgan, WW | 2 |
3 review(s) available for n-methylaspartate and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Alcohol withdrawal syndrome in trauma patients: a review.
Topics: Alcohol Deterrents; Alcoholism; Benzodiazepines; Diagnosis, Differential; gamma-Aminobutyric Acid; Humans; Multiple Trauma; N-Methylaspartate; Neurotransmitter Agents; Substance Withdrawal Syndrome; Trauma Severity Indices | 2010 |
The role of the NMDA receptor in ethanol withdrawal.
Topics: Animals; Cerebellum; Ethanol; Humans; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1994 |
Afferent effects on locus coeruleus in opiate withdrawal.
Topics: Afferent Pathways; Animals; Cats; Clonidine; Dizocilpine Maleate; Kynurenic Acid; Locus Coeruleus; Morphine; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Substance Withdrawal Syndrome | 1991 |
1 trial(s) available for n-methylaspartate and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Effects of ketamine on precipitated opiate withdrawal.
Topics: Adolescent; Adult; Anesthesia, General; Anesthetics, Dissociative; Cardiovascular System; Data Interpretation, Statistical; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Hydrocortisone; Infusions, Intravenous; Ketamine; Male; Morphine; N-Methylaspartate; Narcotic Antagonists; Narcotics; Placebos; Prospective Studies; Substance Withdrawal Syndrome; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2006 |
41 other study(ies) available for n-methylaspartate and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Altered relation between lipopolysaccharide-induced inflammatory response and excitotoxicity in rat organotypic hippocampal slice cultures during ethanol withdrawal.
Topics: Animals; Drug Interactions; Ethanol; Hippocampus; Inflammation; Lipopolysaccharides; Microglia; N-Methylaspartate; Neurons; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Tissue Culture Techniques; Tumor Necrosis Factor-alpha | 2015 |
Inhibition of sigma-1 receptor reduces N-methyl-D-aspartate induced neuronal injury in methamphetamine-exposed and -naive hippocampi.
Topics: Animals; Calcium; Central Nervous System Stimulants; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Female; Hippocampus; Male; Methamphetamine; N-Methylaspartate; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, sigma; Sigma-1 Receptor; Substance Withdrawal Syndrome | 2010 |
Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults.
Topics: Animals; Cannabinoids; Cell Death; Cells, Cultured; Ethanol; Excitatory Amino Acid Agonists; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Substance Withdrawal Syndrome | 2011 |
Genetic dissociation of opiate tolerance and physical dependence in delta-opioid receptor-1 and preproenkephalin knock-out mice.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Enkephalins; Gene Targeting; Mice; Mice, Knockout; Morphine; Morphine Dependence; N-Methylaspartate; Protein Precursors; Receptors, Opioid, delta; Substance Withdrawal Syndrome | 2002 |
Ethanol withdrawal hyper-responsiveness mediated by NMDA receptors in spinal cord motor neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cyclic AMP-Dependent Protein Kinases; Ethanol; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; Glutamic Acid; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Substance Withdrawal Syndrome | 2003 |
The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors.
Topics: Animals; Dizocilpine Maleate; Ethanol; Female; Hippocampus; Male; N-Methylaspartate; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2003 |
Development of behavioral sensitization to the cocaine-like fungicide triadimefon is prevented by AMPA, NMDa, DA D1 but not DA D2 receptor antagonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Corpus Striatum; Drug Administration Schedule; Fungicides, Industrial; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Piperazines; Quinoxalines; Receptors, AMPA; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Remoxipride; Substance Withdrawal Syndrome; Time Factors; Triazoles | 2004 |
Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Blotting, Western; Central Nervous System Stimulants; Dopamine; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; In Vitro Techniques; Male; Membrane Potentials; Motor Activity; N-Methylaspartate; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Synapses; Time Factors; Transferrin; Ventral Tegmental Area | 2004 |
Central amygdala ERK signaling pathway is critical to incubation of cocaine craving.
Topics: Amygdala; Anesthetics, Local; Animals; Behavior, Addictive; Behavior, Animal; Blotting, Western; Butadienes; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; Food; Injections, Intravenous; Male; N-Methylaspartate; Nitriles; Phosphorylation; Rats; Rats, Long-Evans; Reinforcement, Psychology; Self Administration; Signal Transduction; Substance Withdrawal Syndrome; Time Factors | 2005 |
The role of the NO/NMDA pathways in the development of morphine withdrawal induced by naloxone in vitro.
Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine Dependence; N-Methylaspartate; Naloxone; Nitric Oxide; Signal Transduction; Substance Withdrawal Syndrome | 2005 |
Involvement of the bed nucleus of the stria terminalis activated by the central nucleus of the amygdala in the negative affective component of morphine withdrawal in rats.
Topics: Amygdala; Animals; Avoidance Learning; Behavior, Animal; Cell Count; Conditioning, Psychological; Drug Interactions; Immunohistochemistry; Male; Morphine; Morphine Dependence; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neural Pathways; Neurons; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Septal Nuclei; Substance Withdrawal Syndrome | 2005 |
Long-lasting impairment of associative learning is correlated with a dysfunction of N-methyl-D-aspartate-extracellular signaling-regulated kinase signaling in mice after withdrawal from repeated administration of phencyclidine.
Topics: Amygdala; Animals; Conditioning, Psychological; Extracellular Signal-Regulated MAP Kinases; Fear; Hippocampus; Learning Disabilities; MAP Kinase Signaling System; Mice; N-Methylaspartate; Phencyclidine; Substance Withdrawal Syndrome | 2005 |
Potential value of changes in cell markers in organotypic hippocampal cultures associated with chronic EtOH exposure and withdrawal: comparison with NMDA-induced changes.
Topics: Animals; Antigens, Nuclear; Biomarkers; Calbindin 1; Calbindins; Cell Division; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Excitatory Amino Acid Agonists; Female; Glial Fibrillary Acidic Protein; Hippocampus; Male; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Organ Culture Techniques; Propidium; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Substance Withdrawal Syndrome | 2006 |
Allosteric regulation of the N-methyl-D-aspartate receptor-linked ion channel complex and effects of ethanol in ethanol-withdrawal seizure-prone and -resistant mice.
Topics: Allosteric Regulation; Animals; Cerebral Cortex; Dizocilpine Maleate; Ethanol; Genetic Predisposition to Disease; Glycine; Hippocampus; Ion Channels; Male; Mice; Mice, Mutant Strains; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Spermidine; Substance Withdrawal Syndrome | 1995 |
Increases in non-N-methyl-D-aspartate glutamatergic transmission, but no change in gamma-aminobutyric acidB transmission, in CA1 neurons during withdrawal from in vivo chronic ethanol treatment.
Topics: Animals; Ethanol; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Substance Withdrawal Syndrome; Synaptic Transmission | 1995 |
Tolerance to competitive NMDA antagonists, but no crosstolerance with barbiturates.
Topics: 2-Amino-5-phosphonovalerate; Animals; Ataxia; Behavior, Animal; Dizocilpine Maleate; Drug Tolerance; Hypnotics and Sedatives; Male; Mice; Motor Activity; N-Methylaspartate; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome | 1995 |
Ethanol inhibits NMDA-receptor mediated regulation of immediate early gene expression.
Topics: Alcoholism; Animals; Brain; Caffeine; Dizocilpine Maleate; Ethanol; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Kainic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Substance Withdrawal Syndrome; Tissue Distribution | 1993 |
Increased NMDA-induced excitability during ethanol withdrawal: a behavioural and histological study.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Ethanol; Hippocampus; Injections; Male; N-Methylaspartate; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 1995 |
Increased N-methyl-D-aspartate (NMDA) activity in the mouse spinal cord following morphine does not mediate opioid withdrawal.
Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Injections, Spinal; Male; Mice; Morphine; N-Methylaspartate; Naloxone; Piperazines; Receptors, N-Methyl-D-Aspartate; Reference Values; Spinal Cord; Stereotyped Behavior; Substance Withdrawal Syndrome | 1994 |
Modulation of alcohol preference by NMDA antagonists in male rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Brain; Capillary Permeability; Choice Behavior; Ethanol; Magnesium; Male; Motor Activity; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 1993 |
Possible involvement of NMDA receptor-mediated transmission in barbiturate physical dependence.
Topics: 2-Amino-5-phosphonovalerate; Animals; Barbital; Bicuculline; Cerebral Cortex; Dizocilpine Maleate; Hippocampus; Male; Mice; Motor Activity; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Seizures; Substance Withdrawal Syndrome | 1994 |
Sensitivity to N-methyl-D-aspartic acid-induced convulsions is genetically associated with resistance to ethanol withdrawal seizures.
Topics: Animals; Disease Susceptibility; Ethanol; Mice; Mice, Inbred Strains; N-Methylaspartate; Seizures; Substance Withdrawal Syndrome | 1993 |
Behavioral effects of MK-801 in morphine-dependent and non-dependent mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Motor Activity; N-Methylaspartate; Naloxone; Narcotic Antagonists; Substance Withdrawal Syndrome | 1996 |
Ethanol attenuation of morphine dependence: comparison to dizocilpine.
Topics: Animals; Behavior, Animal; Central Nervous System Depressants; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Male; Morphine Dependence; N-Methylaspartate; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1997 |
CCK(B) antagonists protect against some aspects of the ethanol withdrawal syndrome.
Topics: Acoustic Stimulation; Alcoholism; Animals; Anti-Anxiety Agents; Behavior, Animal; Central Nervous System Depressants; Dipeptides; Ethanol; Excitatory Amino Acid Agonists; Handling, Psychological; Indoles; Male; Meglumine; Mice; Mice, Inbred Strains; N-Methylaspartate; Receptors, Cholecystokinin; Seizures; Substance Withdrawal Syndrome | 1998 |
Infusional high-dose application of the calcium-channel-blocking and antiglutamatergic agent caroverine in the treatment of alcohol withdrawal (DSM-III-R 291.80).
Topics: Adult; Alcohols; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Calcium Channel Blockers; Excitatory Amino Acid Antagonists; Female; Humans; Infusion Pumps; Infusions, Intravenous; Male; Middle Aged; N-Methylaspartate; Pilot Projects; Quinoxalines; Substance Withdrawal Syndrome | 1998 |
A comparison of the effects of clonidine and CNQX infusion into the locus coeruleus and the amygdala on naloxone-precipitated opiate withdrawal in the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Amygdala; Animals; Clonidine; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutamine; Locus Coeruleus; Male; Morphine Dependence; N-Methylaspartate; Naloxone; Narcotic Antagonists; Norepinephrine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1998 |
Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability.
Topics: Action Potentials; Amphetamine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Ethanol; Hyperkinesis; In Vitro Techniques; Male; Mice; N-Methylaspartate; Neurons; Potassium Chloride; Substance Withdrawal Syndrome; Ventral Tegmental Area | 1998 |
Induction of cyclooxygenase-2 in brain during acute and chronic ethanol treatment and ethanol withdrawal.
Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Brain; Cyclooxygenase 2; Disease Models, Animal; Enzyme Induction; Ethanol; Immunohistochemistry; Isoenzymes; Kainic Acid; Male; N-Methylaspartate; Peroxidases; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1999 |
Glutamate-induced increase of extracellular glutamate through N-methyl-D-aspartate receptors in ethanol withdrawal.
Topics: Animals; Corpus Striatum; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Feedback; Glutamic Acid; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Up-Regulation | 1999 |
Autoradiographic study of NMDA-displaceable [3H]glutamate and [3H]MK-801 binding during butorphanol withdrawal in the rat brain.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Butorphanol; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Intraventricular; Male; N-Methylaspartate; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tritium | 1999 |
Chronic morphine increases GABA tone on serotonergic neurons of the dorsal raphe nucleus: association with an up-regulation of the cyclic AMP pathway.
Topics: Adenylyl Cyclases; Analgesics, Opioid; Animals; Cardiovascular Agents; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Isoquinolines; Male; Membrane Potentials; Morphine; N-Methylaspartate; Neural Inhibition; Periaqueductal Gray; Phenylephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Substance Withdrawal Syndrome; Sulfonamides; Sympathomimetics; Tetrazoles; Tetrodotoxin; Thionucleotides | 2000 |
Dynamics of NMDAR-mediated neurotoxicity during chronic ethanol exposure and withdrawal.
Topics: Alcoholism; Animals; Biological Transport; Drug Interactions; Ethanol; Female; Intercalating Agents; Male; N-Methylaspartate; Neurotoxicity Syndromes; Propidium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2000 |
Further evidence for a role of NMDA receptors in the locus coeruleus in the expression of withdrawal syndrome from opioids.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Locus Coeruleus; Male; N-Methylaspartate; Naloxone; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2001 |
Morphine acutely and persistently attenuates nonvesicular GABA release in rat nucleus accumbens.
Topics: Analgesics; Animals; Benzeneacetamides; Carrier Proteins; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Male; Morphine; Morphine Dependence; N-Methylaspartate; Naloxone; Neural Inhibition; Neurons; Nucleus Accumbens; Organ Culture Techniques; Pyrrolidines; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Tritium | 2001 |
Increased sensitivity to NMDA is involved in alcohol-withdrawal induced cytotoxicity observed in primary cultures of cortical neurones chronically pre-treated with ethanol.
Topics: Animals; Calcium; Cells, Cultured; Ethanol; In Vitro Techniques; N-Methylaspartate; Neocortex; Neurons; Rats; Substance Withdrawal Syndrome | 2002 |
Alcohol withdrawal reaction as a result of adaptive changes of excitatory amino acid receptors.
Topics: Animals; Brain; Dizocilpine Maleate; Electrophysiology; Ethanol; Injections, Intraperitoneal; Kainic Acid; Male; N-Methylaspartate; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Substance Withdrawal Syndrome | 1992 |
Comparison of the effects of the uncompetitive N-methyl-D-aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine (ADCI) with its structural analogs dizocilpine (MK-801) and carbamazepine on ethanol withdrawal seizur
Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Ethanol; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Seizures; Substance Withdrawal Syndrome; Tremor | 1992 |
Glutamate antagonists prevent morphine withdrawal in mice and guinea pigs.
Topics: Acetylcholine; Animals; Cerebral Cortex; Dizocilpine Maleate; Drug Implants; Drug Tolerance; Excitatory Amino Acid Antagonists; Glutamates; Guinea Pigs; Kinetics; Mice; Morphine; N-Methylaspartate; Naloxone; Parietal Lobe; Psychotropic Drugs; Substance Withdrawal Syndrome | 1991 |
Increased response of cerebellar cGMP to kainate but not NMDA or quisqualate following barbital withdrawal from dependent rats.
Topics: Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Kainic Acid; N-Methylaspartate; Neuromuscular Depolarizing Agents; Oxadiazoles; Quisqualic Acid; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1989 |
2-Amino-7-phosphonoheptanoic acid, a selective antagonist of N-methyl-D-aspartate, prevents barbital withdrawal-induced convulsions and the elevation of cerebellar cyclic GMP in dependent rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Barbital; Barbiturates; Cerebellum; Cyclic GMP; Female; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1987 |