Page last updated: 2024-08-22

n-methylaspartate and Stroke

n-methylaspartate has been researched along with Stroke in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's18 (51.43)29.6817
2010's13 (37.14)24.3611
2020's4 (11.43)2.80

Authors

AuthorsStudies
Hayashi, H; Inoue, D; Iwatani, Y; Ohata, M; Sato, S; Suzuki, K; Takagi, N; Yamada, M; Yuan, B1
Boychuk, J; Jiang, A; Lai, TKY; Liu, F; Su, P; Zhai, D1
Dalmau, J1
Liman, TG; Prüss, H; Siegerink, B; Sperber, PS1
Ayuso-Dolado, S; Díaz-Guerra, M; Esteban-Ortega, GM; Vidaurre, ÓG1
Alasoadura, M; Chuquet, J; Clarkson, AN; Gach-Janczak, K; Gowing, EK; Hazime, M; Lamtahri, R; Lefranc, B; Lehongre, K; Leprince, J; Mandrup, S; Marcher, AB; Maucotel, J; Nagaraja, RY; Quilichini, PP; Vaudry, D1
Cortés-Montero, E; Garzón, J; Onetti, Y; Rodríguez-Muñoz, M; Sánchez-Blázquez, P1
Haydon, PG; Hines, DJ1
Mokrushin, AA; Pavlinova, LI1
Wang, ES; Wu, F; Yu, G1
Attwell, D; Hamilton, NB; Kolodziejczyk, K; Kougioumtzidou, E1
Bandet, MV; Bialecki, J; Colicos, MA; Ikuta, NT; Lohman, AW; Ma, EM; Maslieieva, V; Rakai, BD; Rilea, T; Scott, L; Teskey, GC; Thompson, RJ; Weilinger, NL; Winship, IR1
David, KK; Dawson, TM; Dawson, VL; Koehler, RC; Li, X; Xu, Z; Yang, ZJ; Zhang, J1
Dawson, TM; Dawson, VL; Eacker, SM; Gronostajski, RM; Hong, SJ; Zheng, S1
Abraini, JH; Colloc'h, N; Colomb, DG; David, HN; Haelewyn, B; Risso, JJ1
Agin, V; Ali, C; Gauberti, M; Hébert, M; Jullienne, A; Le Béhot, A; Lesept, F; Louessard, M; Maubert, E; Montagne, A; Orset, C; Vivien, D1
Dawson, TM; Dawson, VL; Eacker, SM; Harraz, MM; Wang, X1
Greenberg, DA; Jin, K; Mao, XO; Parmentier-Batteur, S; Xie, L1
Ali, C; Buisson, A; Carmeliet, P; Docagne, F; Fernández-Monreal, M; Gabriel, C; Lesné, S; MacKenzie, ET; Nicole, O; Plawinski, L; Vivien, D1
Fleming, SM; Schallert, T; Woodlee, MT1
Abraini, JH; Buisson, A; Chazalviel, L; David, HN; Lemaire, M; Leveille, F; MacKenzie, ET1
Barber, PA; Buchan, AM; Hill, MD; Hoyte, L1
Chan, LN; Sucher, NJ; Sun, X1
Andreasson, KA; Li, H; McCullough, LD; Pin, S; Wang, MM; Zeng, Z1
Chuang, DM1
Ali, C; Fernandez-Monreal, M; Lebeurrier, N; Liot, G; Lopez-Atalaya, JP; Orset, C; Sonderegger, P; Vivien, D1
Sucher, NJ1
Attkisson, E; Blair, RE; DeLorenzo, RJ; Deshpande, LS; Lou, JK; Mian, A; Sombati, S1
Chacon, MR; Jensen, MB; Sattin, JA; Zivin, JA1
Fisher, M; Schaebitz, W1
Anderson, JW; Bains, JS; Ferguson, AV; Follwell, MJ; Latchford, KJ1
Iadecola, C; Kazama, K; Niwa, K; Ross, ME; Sugimoto, K1
Asai, S; Ishikawa, K; Kanematsu, K; Kohno, T; Kunimatsu, T; Misaki, T1
Bossy-Wetzel, E; Cui, J; Ju, C; Li, Z; Lipton, SA; Mathews, E; Okamoto, S; Salvesen, GS; Scholzke, MN1
Clapp-Lilly, KL; Drew, KL; Duffy, LK; Harris, PL; Perry, G; Smith, MA; Zhu, X1

Reviews

6 review(s) available for n-methylaspartate and Stroke

ArticleYear
Should the injured and intact hemispheres be treated differently during the early phases of physical restorative therapy in experimental stroke or parkinsonism?
    Physical medicine and rehabilitation clinics of North America, 2003, Volume: 14, Issue:1 Suppl

    Topics: Animals; Brain; Dendrites; Disease Models, Animal; Functional Laterality; N-Methylaspartate; Neuroprotective Agents; Parkinsonian Disorders; Receptors, GABA; Recovery of Function; Stroke; Synapses; Time Factors

2003
The rise and fall of NMDA antagonists for ischemic stroke.
    Current molecular medicine, 2004, Volume: 4, Issue:2

    Topics: Animals; Brain Ischemia; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Antagonists; Guanidines; Humans; Indoles; Ischemia; N-Methylaspartate; Neurons; Pipecolic Acids; Receptors, N-Methyl-D-Aspartate; Stroke

2004
The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials.
    Annals of the New York Academy of Sciences, 2005, Volume: 1053

    Topics: Affect; Animals; Antimanic Agents; Apoptosis; Excitatory Amino Acid Agonists; Humans; Lithium; N-Methylaspartate; Rats; Stroke; Valproic Acid

2005
Insights from molecular investigations of traditional Chinese herbal stroke medicines: implications for neuroprotective epilepsy therapy.
    Epilepsy & behavior : E&B, 2006, Volume: 8, Issue:2

    Topics: Apoptosis; Caspases; Drugs, Chinese Herbal; Epilepsy; Humans; N-Methylaspartate; Phytotherapy; Receptors, N-Methyl-D-Aspartate; Stroke

2006
Neuroprotection in cerebral ischemia: emphasis on the SAINT trial.
    Current cardiology reports, 2008, Volume: 10, Issue:1

    Topics: Acute Disease; Benzenesulfonates; Brain Ischemia; Cardiovascular Agents; Clinical Trials as Topic; GABA Agonists; Humans; Hypothermia; N-Methylaspartate; Narcotic Antagonists; Neuroprotective Agents; Stroke; Tissue Plasminogen Activator

2008
An overview of acute stroke therapy: past, present, and future.
    Archives of internal medicine, 2000, Nov-27, Volume: 160, Issue:21

    Topics: Acute Disease; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antibodies; Brain Ischemia; Calcium Channel Blockers; Cardiovascular Agents; Cell Adhesion Molecules; Clinical Trials as Topic; Cytidine Diphosphate Choline; Cytokines; Drug Therapy, Combination; Fibrinolytic Agents; Free Radical Scavengers; gamma-Aminobutyric Acid; Growth Substances; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; N-Methylaspartate; Neuroprotective Agents; Nootropic Agents; Piperidines; Stroke; Thiazoles; Thrombolytic Therapy

2000

Other Studies

29 other study(ies) available for n-methylaspartate and Stroke

ArticleYear
Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA.
    Scientific reports, 2019, 08-13, Volume: 9, Issue:1

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Endocytosis; Furin; Humans; Low Density Lipoprotein Receptor-Related Protein-1; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Rats; Receptors, LDL; Signal Transduction; Stroke; trans-Golgi Network

2019
The receptor-receptor interaction between mGluR1 receptor and NMDA receptor: a potential therapeutic target for protection against ischemic stroke.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:12

    Topics: Animals; Cells, Cultured; Gene Expression Regulation; Hippocampus; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 6; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stroke

2019
Letter by Dalmau Regarding Article, "Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B)".
    Stroke, 2020, Volume: 51, Issue:2

    Topics: Autoantibodies; Humans; N-Methylaspartate; Stroke

2020
Response by Sperber et al to Letter Regarding Article, "Serum Anti-NMDA (N-Methyl-D-Aspartate)-Receptor Antibodies and Long-Term Clinical Outcome After Stroke (PROSCIS-B)".
    Stroke, 2020, Volume: 51, Issue:2

    Topics: Autoantibodies; Humans; N-Methylaspartate; Stroke

2020
A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke.
    Theranostics, 2021, Volume: 11, Issue:14

    Topics: Animals; Brain Ischemia; Calpain; Cell Survival; Cell-Penetrating Peptides; Cells, Cultured; Disease Models, Animal; Disks Large Homolog 4 Protein; Down-Regulation; Excitatory Amino Acid Agonists; HEK293 Cells; Humans; Male; Mice; Mice, Inbred BALB C; Movement Disorders; N-Methylaspartate; Neurons; Neuroprotection; Stroke

2021
The Gliopeptide ODN, a Ligand for the Benzodiazepine Site of GABA
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021, 08-18, Volume: 41, Issue:33

    Topics: Adult; Animals; Astrocytes; Cortical Spreading Depression; Diazepam Binding Inhibitor; Drug Implants; Evoked Potentials, Somatosensory; Female; GABA-A Receptor Agonists; Humans; Hydrogels; Infarction, Middle Cerebral Artery; Intracranial Thrombosis; Light; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Neuropeptides; Patch-Clamp Techniques; Peptide Fragments; Rats; Receptors, GABA-A; Rose Bengal; Single-Blind Method; Stroke

2021
Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor.
    Molecular brain, 2018, 09-17, Volume: 11, Issue:1

    Topics: Animals; Anticonvulsants; Cannabidiol; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Mice, Knockout; Morphine; N-Methylaspartate; Nociception; Protein Subunits; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Seizures; Sigma-1 Receptor; Stroke

2018
Inhibition of a SNARE-sensitive pathway in astrocytes attenuates damage following stroke.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-06, Volume: 33, Issue:10

    Topics: Animals; Astrocytes; Brain Infarction; Disease Models, Animal; Excitatory Amino Acid Agonists; Gene Expression Regulation; Green Fluorescent Proteins; Intracranial Thrombosis; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Neurons; Phosphopyruvate Hydratase; Psychomotor Performance; Signal Transduction; SNARE Proteins; Stroke

2013
Effects of the blood components on the AMPA and NMDA synaptic responses in brain slices in the onset of hemorrhagic stroke.
    General physiology and biophysics, 2013, Volume: 32, Issue:4

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Transfusion, Autologous; Brain; Erythrocytes; Excitatory Postsynaptic Potentials; In Vitro Techniques; Intracranial Hemorrhages; N-Methylaspartate; Olfactory Pathways; Rats; Stroke; Synapses

2013
BQ-869, a novel NMDA receptor antagonist, protects against excitotoxicity and attenuates cerebral ischemic injury in stroke.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:2

    Topics: Animals; Brain Ischemia; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Heterocyclic Compounds, 4 or More Rings; Hippocampus; N-Methylaspartate; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stroke

2015
Proton-gated Ca(2+)-permeable TRP channels damage myelin in conditions mimicking ischaemia.
    Nature, 2016, Jan-28, Volume: 529, Issue:7587

    Topics: Animals; Brain Ischemia; Calcium; Calcium Signaling; Electric Conductivity; Female; Hydrogen-Ion Concentration; Magnesium; Male; Mice; Mice, Transgenic; Multiple Sclerosis; Myelin Sheath; N-Methylaspartate; Oligodendroglia; Potassium; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stroke; Transient Receptor Potential Channels; White Matter

2016
Metabotropic NMDA receptor signaling couples Src family kinases to pannexin-1 during excitotoxicity.
    Nature neuroscience, 2016, Volume: 19, Issue:3

    Topics: Animals; Calcium; Cell Death; Connexins; Dizocilpine Maleate; Magnesium; Membrane Potentials; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Rats; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Stroke

2016
Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 299, Issue:1

    Topics: Adenosine Diphosphate Ribose; Animals; Apoptosis Inducing Factor; Caspases; Cell Death; D-Aspartic Acid; DNA Fragmentation; Endodeoxyribonucleases; Enzyme Inhibitors; Female; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Reperfusion; Stroke

2010
NMDA-induced neuronal survival is mediated through nuclear factor I-A in mice.
    The Journal of clinical investigation, 2010, Volume: 120, Issue:7

    Topics: Animals; Cell Death; Cell Differentiation; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Neuroprotective Agents; NFI Transcription Factors; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Stroke

2010
Interactions between nitrous oxide and tissue plasminogen activator in a rat model of thromboembolic stroke.
    Anesthesiology, 2011, Volume: 115, Issue:5

    Topics: Animals; Binding Sites; Brain; Disease Models, Animal; Isoflurane; Male; N-Methylaspartate; Neuroprotective Agents; Nitrous Oxide; Rats; Rats, Sprague-Dawley; Stroke; Thromboembolism; Tissue Plasminogen Activator; Xenon

2011
Memantine improves safety of thrombolysis for stroke.
    Stroke, 2012, Volume: 43, Issue:10

    Topics: Animals; Cells, Cultured; Cerebral Cortex; Chemotherapy, Adjuvant; Excitatory Amino Acid Antagonists; Fibrinolytic Agents; In Vitro Techniques; Magnetic Resonance Imaging; Male; Memantine; Mice; Models, Animal; N-Methylaspartate; Stroke; Thrombolytic Therapy; Tissue Plasminogen Activator; Treatment Outcome

2012
MicroRNA-223 is neuroprotective by targeting glutamate receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Nov-13, Volume: 109, Issue:46

    Topics: 3' Untranslated Regions; Animals; Calcium; Calcium Signaling; Excitatory Postsynaptic Potentials; HEK293 Cells; Hippocampus; Humans; Mice; MicroRNAs; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stroke

2012
Increased severity of stroke in CB1 cannabinoid receptor knock-out mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-15, Volume: 22, Issue:22

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Cerebrovascular Circulation; Disease Models, Animal; Genotype; Heterozygote; Homozygote; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Phenotype; Receptors, Cannabinoid; Receptors, Drug; Reperfusion; Stroke; Survival Rate

2002
Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis.
    Molecular and cellular neurosciences, 2002, Volume: 21, Issue:4

    Topics: Animals; Animals, Newborn; Astrocytes; Brain; Calcium Signaling; Cells, Cultured; Coculture Techniques; DNA-Binding Proteins; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Mice; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Plasminogen Activator Inhibitor 1; Recombinant Fusion Proteins; Smad3 Protein; Stroke; Tissue Plasminogen Activator; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002
Reduction of ischemic brain damage by nitrous oxide and xenon.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:10

    Topics: Anesthetics, Inhalation; Animals; Brain Ischemia; Calcium; Cells, Cultured; Excitatory Amino Acid Agonists; Male; Motor Activity; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitrous Oxide; Postural Balance; Rats; Rats, Sprague-Dawley; Stroke; Xenon

2003
Magnesium as NMDA receptor blocker in the traditional Chinese medicine Danshen.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2005, Volume: 12, Issue:3

    Topics: Animals; Cerebral Cortex; Drugs, Chinese Herbal; Magnesium; Membrane Potentials; Mice; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Phytotherapy; Plant Extracts; Plant Roots; Receptors, N-Methyl-D-Aspartate; Salvia miltiorrhiza; Stroke

2005
Sex differences in cell death.
    Annals of neurology, 2005, Volume: 58, Issue:2

    Topics: Animals; Animals, Newborn; Cell Death; Disease Models, Animal; DNA-Binding Proteins; Drug Interactions; Female; Genotype; Glucose; High Mobility Group Proteins; Hippocampus; Hypoxia; Indazoles; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide; Organ Culture Techniques; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Characteristics; SOXB1 Transcription Factors; Stroke; Superoxide Dismutase; Time Factors; Transcription Factors

2005
The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo.
    Molecular and cellular neurosciences, 2005, Volume: 30, Issue:4

    Topics: Animals; Apoptosis; Brain; Brain Ischemia; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Male; Mice; N-Methylaspartate; Neurons; Neuropeptides; Neuroprotective Agents; Neuroserpin; Neurotoxins; Receptors, N-Methyl-D-Aspartate; Serpins; Stroke

2005
Time course and mechanism of hippocampal neuronal death in an in vitro model of status epilepticus: role of NMDA receptor activation and NMDA dependent calcium entry.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: Animals; Calcium; Calcium Signaling; Cell Death; Cells, Cultured; Data Interpretation, Statistical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Magnesium Deficiency; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Status Epilepticus; Stroke

2008
Slowly inactivating potassium conductance (I(D)): a potential target for stroke therapy.
    Stroke, 2001, Volume: 32, Issue:11

    Topics: 4-Aminopyridine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Death; Cells, Cultured; Electric Conductivity; Excitatory Postsynaptic Potentials; Humans; Hypothalamus; Kinetics; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Stroke

2001
Increased susceptibility to ischemic brain injury in cyclooxygenase-1-deficient mice.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2001, Volume: 21, Issue:12

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Cyclooxygenase 1; Disease Susceptibility; Excitatory Amino Acid Agonists; Female; Infarction, Middle Cerebral Artery; Isoenzymes; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurotoxins; Parietal Lobe; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Stroke

2001
Effects of glutamate receptor agonist on extracellular glutamate dynamics during moderate cerebral ischemia.
    Brain research, 2001, Dec-27, Volume: 923, Issue:1-2

    Topics: Animals; Carotid Artery, Common; Cerebrovascular Circulation; Corpus Striatum; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Ischemic Attack, Transient; Kainic Acid; Male; Microdialysis; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Glutamate; Stroke

2001
Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Mar-19, Volume: 99, Issue:6

    Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Caspases; Cells, Cultured; Cerebral Cortex; DNA; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Mutation; Myogenic Regulatory Factors; N-Methylaspartate; Neurons; Protein Binding; Protein Processing, Post-Translational; Rats; Reperfusion Injury; Response Elements; RNA, Messenger; Stroke; Transcription Factors; Transcription, Genetic

2002
Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity.
    International journal of circumpolar health, 2002, Volume: 61, Issue:1

    Topics: Animals; Antioxidants; Brain; Excitatory Amino Acid Antagonists; In Vitro Techniques; Melatonin; Mice; N-Methylaspartate; Stroke

2002