n-methylaspartate has been researched along with Pregnancy in 234 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (2.56) | 18.7374 |
| 1990's | 88 (37.61) | 18.2507 |
| 2000's | 88 (37.61) | 29.6817 |
| 2010's | 42 (17.95) | 24.3611 |
| 2020's | 10 (4.27) | 2.80 |
| Authors | Studies |
|---|---|
| Janicot, R; Shao, LR; Stafstrom, CE | 1 |
| Bhatia, A; Joshi, R; Kaur, G; Kumar, R; Medhi, B; Mishra, A; Prajapat, M; Sarma, P; Sharma, A; Singla, R | 1 |
| Pavlinova, EB; Savchenko, OA | 1 |
| Chen, J; Hu, B; Shen, M; Wang, F; Yang, Y; Zhou, Q; Zou, X | 1 |
| Kim, EJ; Kim, MJ; Lee, M; Yum, MS | 1 |
| Filip, M; Kalinichenko, LS; Kornhuber, J; Lenz, B; Müller, CP; Smaga, I | 1 |
| Kim, EJ; Kim, K; Kim, MJ; Lee, M; Yeom, J; Yum, MS | 1 |
| Bigagli, E; Caffino, L; Castillo Díaz, F; Curti, L; Dani, C; Fumagalli, F; Gerace, E; Ilari, A; Luceri, C; Mannaioni, G; Masi, A; Mottarlini, F | 1 |
| Chachua, T; Chern, CR; Velíšek, L; Velíšková, J | 1 |
| Kim, EJ; Kim, MJ; Ko, TS; Lee, M; Woo, DC; Yum, MS | 1 |
| Edwards, KA; Zup, SL | 1 |
| Elefant, F; Gao, WJ; Gulchina, Y; Snyder, MA; Xu, SJ | 1 |
| Cananzi, SG; Mayhan, WG | 1 |
| Chern, CJ; Chern, CR; Velíšek, L; Velíšková, J | 1 |
| Felszeghy, K; Gódor-Kacsándi, A; Luiten, PG; Nyakas, C; Ranky, M | 1 |
| Ma, J; Mao, M; Tong, Y; Yu, D | 1 |
| Dong, Z; Girling, K; Lee, W; Lin, SZ; Shyu, WC; Taghibiglou, C; Wang, YT; Zhang, S | 1 |
| Luo, J; Pepperberg, DR; Qin, Z; Tavassoli, E; Thatcher, GR; Vandevrede, L; Yue, L | 1 |
| Chen, H; Matta, SG; Roguski, EE; Sharp, BM | 1 |
| Battaglia, GS; Colciaghi, F; Finardi, A; Locatelli, D; Nobili, P; Spigolon, G | 1 |
| Firl, DJ; Getsy, PM; Jantzie, LL; Miller, RH; Robinson, S; Wilson, CG | 1 |
| Shang, AJ; Wang, J; Yang, G; Zhang, Y; Zou, LP | 1 |
| Kohlmeier, KA; McNair, LF | 1 |
| Alaux-Cantin, S; Antol, J; Fedorenko, O; Kervern, M; Naassila, M; Pierrefiche, O; Silvestre de Ferron, B | 1 |
| Ding, S; Han, S; Li, J; Li, Y; Sun, W; Wang, W; Yin, Y | 1 |
| Cortés, P; Harraz, MM; Snyder, SH; Tyagi, R | 1 |
| Kato, F; Takahashi, Y; Tsuji, M; Watabe, AM | 1 |
| Bak, LK; Bulaj, G; Flynn, SP; Müller, MS; Schousboe, A; Walls, AB; West, PJ; White, HS | 1 |
| Ju, J; Shang, NX; Shi, XY; Wang, J; Zhang, JY; Zhao, JB; Zou, LP | 1 |
| Aguayo, LG; Fernández-Pérez, EJ; Peoples, RW; Peters, C; Sepúlveda, FJ | 1 |
| Burrone, J; Fleck, RA; Grillo, F; Jackson, RE; Lowe, AS; Neves, G; O'Donnell, C; Rigby, M; Vizcay-Barrena, G; Walker, AS | 1 |
| Chow, N; Davis, TP; Guo, H; Singh, I; Thiyagarajan, M; Wang, Y; Zlokovic, BV | 1 |
| Azeddine, B; d'Asti, E; Long, H; Moreau, A; Naef, L; Walker, CD; Xu, Z | 1 |
| Arutyunian, AV; Bulygina, ER; Kozina, LS; Makhro, AV; Mashkina, AP; Solenaya, OA; Trunova, OA | 1 |
| Barrett, T; Chow, N; Deane, R; Fernández, JA; Griffin, JH; Guo, H; Singh, I; Wang, Y; Zlokovic, BV | 1 |
| Baudry, M; Dominguez, R; Hu, E; Zhou, M | 1 |
| Hamill, CE; Lyuboslavsky, P; Mannaioni, G; Sastre, AA; Traynelis, SF | 1 |
| Bernásková, K; Matejovská, I; Rokyta, R; Schutová, B; Slamberová, R | 1 |
| Chen, JF; Chiodi, V; Domenici, MR; Ferrante, A; Frank, C; Ledent, C; Martire, A; Pepponi, R; Popoli, P; Tebano, MT | 1 |
| Igarashi, K; Kashiwagi, K; Kizawa, Y; Kusama, T; Masuko, T; Miyake, M; Namiki, R; Nemoto, Y; Suzuki, T | 1 |
| Jantas, D; Jaworska-Feil, L; Lason, W; Lipkowski, AW | 1 |
| Chang, HW; Chen, CC; Chen, JY; Chen, YC; Chou, CM; Hung, CC; Lee, YH; Lin, CH; Wang, CY; Yeh, GC | 1 |
| Albensi, B; Glazner, G; Morissette, M; Odero, G; Schapansky, J | 1 |
| Boix, J; Cauli, O; Felipo, V | 1 |
| Knutson, N; Wood, CE | 1 |
| Garcia-Rill, E; Hayar, A; Hyde, J; Kezunovic, N; Simon, C; Williams, DK; Ye, M | 1 |
| Dudak, A; Federoff, HJ; Kim, J; Lilliehook, C; Lim, ST; Prox, J; Saftig, P | 1 |
| Amigou, E; Calvo, CF; Froger, N; Giaume, C; Kozoriz, MG; Naus, CC; Orellana, JA; Sáez, JC | 1 |
| Balduzzi, M; Bellenchi, GC; Cammarota, R; Carnovale-Scalzo, G; De Nuccio, C; Di Stasi, AM; Frank, C; Leo, L; Malchiodi-Albedi, F; Mallozzi, C; Matteucci, A; Paradisi, S; Scorcia, G; Varano, M; Visentin, S | 1 |
| Bamji, SX; Cynader, MS; Guo, A; Jia, W; Tapia, L | 1 |
| Aguirre, C; Baudry, M; Jayaraman, A; Pike, C | 1 |
| Bernášková, K; Hrubá, L; Matějovská, I; Rokyta, R; Slamberová, R | 1 |
| Chiu, WT; Hung, KS; Lee, YH; Lin, JW; Lin, MS; Sun, YY; Tsai, SH | 1 |
| Garcia-Rill, E; Hayar, A; Simon, C | 1 |
| El-Sayed, M; Hofman-Bang, J; Mikkelsen, JD | 1 |
| Chachua, T; Velíšek, L; Velíšková, J; Yum, MS | 1 |
| Desai, NS; Higgins, EA; Walcott, EC | 1 |
| Friedman, WJ; Huang, Y; Ibáñez-Sandoval, O; Sims, JE; Smith, DE | 1 |
| Blanc, T; Dahmani, S; Jegou-Colleter, S; Laudenbach, V; Marret, S; Tourrel, F | 1 |
| Bonner, H; Courtney, MJ; D'Orsi, B; Düssmann, H; Prehn, JH; Tuffy, LP; Ward, MW; Woods, I | 1 |
| Ding, YX; Shi, XY; Yang, G; Zou, LP | 1 |
| Coquinco, A; Craig, AM; Cynader, M; Kaufman, AM; Lee, H; Milnerwood, AJ; Raymond, LA; Sepers, MD; She, K; Wang, L | 1 |
| Barde, YA; Dekkers, MP; Deogracias, R; Guy, J; Ionescu, MC; Vogt, KE; Yazdani, M | 1 |
| Shang, AJ; Wang, J; Yang, G; Zhang, Y; Zhou, WJ; Zou, LP | 1 |
| Meeker, RB | 1 |
| Soria, JM; Valdeolmillos, M | 1 |
| Boustany, RM; Lockhart, EM; Mehrabani, S; Pearlstein, RD; Penning, DH; Warner, DS | 1 |
| Hasegawa, K; Hirai, K; Kihara, M; Kizaki, Z; Sawada, T; Yoshioka, H | 1 |
| Archer, T; Fredriksson, A | 2 |
| Colonnese, MT; Constantine-Paton, M; Shi, J | 1 |
| Brunette, E; Comas, T; Mealing, G; Monette, R; Morley, P; Small, DL; Tauskela, JS | 1 |
| Kennedy, TE; Luk, KC; Sadikot, AF | 1 |
| Bonicalzi, V; Canavero, S | 1 |
| Farkas, T; Högyes, E; Kiliaan, A; Luiten, PG; Nyakas, C; Penke, B | 1 |
| Ban, JY; Koh, SB; Lee, BY; Seong, YH | 1 |
| Bockaert, J; Lafon-Cazal, M; Lerner-Natoli, M; Milhaud, D; Rondouin, G | 1 |
| Doi, K; Katayama, K; Nakayama, H; Takai, H; Uetsuka, K; Yasoshima, A | 1 |
| Enomoto, A; Ishihama, K; Kogo, M; Koizumi, H; Nomura, K; Tanaka, S; Yamanishi, T | 1 |
| Mashimo, T; Shibuta, S; Varathan, S | 1 |
| Blusztajn, JK; Meck, WH; Mellott, TJ; Williams, CL | 1 |
| Cho, J; Lee, HK | 1 |
| Aizenman, E; Epstein, PM; Herin, GA; Li, Y; Lu, Y; Rosenberg, PA | 1 |
| Olney, JW | 1 |
| Domenici, MR; Martire, A; Pepponi, R; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Bourguignon, JP; Gérard, A; Lebrethon, MC; Parent, AS | 1 |
| Babb, JA; Mann, PE | 1 |
| Baden, DG; Dravid, SM; Murray, TF | 1 |
| Goto, W; Hara, H; Hirao, M; Ikeda, T; Kobayashi, T; Oku, H; Okuno, T; Sugiyama, T; Yoneda, S | 1 |
| Gillessen, T; Grasshoff, C | 1 |
| Funakoshi, H; Ishihara, N; Matsumoto, K; Nakamura, T; Nakano, M; Niimura, M; Takagi, K; Takagi, N; Takeo, S; Tanonaka, K | 1 |
| Rokyta, R; Slamberová, R | 2 |
| Chen, JF; Cunha, RA; Domenici, MR; Grò, MC; Martire, A; Pepponi, R; Popoli, P; Rebola, N; Schwarzschild, MA; Tebano, MT | 1 |
| Komuro, H; Kumada, T; Lakshmana, MK | 1 |
| Baldo, MV; Canteras, NS; Felício, LF; Mota-Ortiz, SR; Sukikara, MH | 1 |
| Cohen, AS; Geddes-Klein, DM; Meaney, DF; Mesfin, MN; Serbest, G | 1 |
| Wang, HM; Zeng, M; Zhang, JY; Zhang, WH; Zhao, CL; Zou, LP | 1 |
| Antonelli, T; Borracci, P; Carratù, MR; Coluccia, A; Cuomo, V; Ferraro, L; Giustino, A; Mazzoni, E; Raisi, E; Renna, G; Tomasini, MC | 1 |
| Billard, JM; Dutar, P; Epelbaum, J; George, O; Le Moal, M; Lemaire, V; Mayo, W; Piazza, PV | 1 |
| Ali, M; Dhawan, A; Johri, A; Parmar, D; Singh, RL; Yadav, S | 1 |
| Oppenheim, RW; Winseck, AK | 1 |
| Lewis, BL; Lipska, BK; O'Donnell, P; Tseng, KY | 1 |
| Erceg, S; Felipo, V; Llansola, M; Monfort, P; Montoliu, C | 1 |
| Asche, S; Jehle, K; Velísek, L; Velísková, J | 1 |
| Brewer, LD; Garcia-Ramos, G; Kraner, S; Landfield, PW; Porter, NM; Rogers, JT; Staton, J; Thibault, O; Thibault, V | 1 |
| Bruno, V; Caruso, A; Matrisciano, F; Melchiorri, D; Molinaro, G; Motolese, M; Nicoletti, F; Orlando, R; Togna, G | 1 |
| Acarin, L; Arís, A; Castellano, B; González, B; González, P; Peluffo, H; Saura, J; Villaverde, A | 1 |
| Jin, S; Kawanokuchi, J; Mizuno, T; Sonobe, Y; Suzumura, A; Takeuchi, H; Wang, J | 1 |
| Harris, AP; Koehler, RC; Ohata, H | 1 |
| Aono, S; Hayakawa, M; Ida, M; Kakizawa, H; Kojima, S; Kuroda, Y; Maeda, H; Matsui, F; Nakanishi, K; Oohira, A; Saito, A; Sato, Y; Tokita, Y | 1 |
| Aoki, H; Hara, A; Kunisada, T; Motohashi, T; Niwa, M; Suzuki, T | 1 |
| Andrews, SB; Brantner, CA; Pivovarova, NB; Smith, CL; Stanika, RI; Watts, CA | 1 |
| Liang, SL; McCarthy, MM; Schwarz, JM; Thompson, SM | 1 |
| Dohrman, DP; Goodlett, CR; Luo, J; Pantazis, NJ; Thomas, JD; West, JR | 1 |
| Cohan, C; Pentney, RJ; Rabin, RA; Zou, JY | 1 |
| Deshpande, SS; Filbert, MG; Smith, CD | 1 |
| MacDermott, AB; Reichling, DB | 1 |
| Emmett, MR; Wood, JA; Wood, PL | 1 |
| Antonov, SM; Gmiro, VE; Johnson, JW; Lukomskaya, NY; Magazanik, LG; Potapyeva, NN | 1 |
| Hayashi, T; Kagaya, A; Motohashi, N; Shimizu, M; Takebayashi, M; Uchitomi, Y; Yamawaki, S | 1 |
| Daval, JL; Koziel, V; Nicolas, F; Oillet, J | 1 |
| Rocha, M; Sur, M | 1 |
| Felipo, V; Grisolía, S; Marcaida, G; Miñana, MD | 1 |
| Ali, SF; Bowyer, JF; Holson, RR; Newport, GD; Slikker, W | 1 |
| Choi, DW; Goldberg, MP; Gottlieb, DI; Huettner, JE; Turetsky, DM | 1 |
| Magistretti, PJ; Pellerin, L; Stella, N | 1 |
| Ghosh, P; Liljelund, P; van den Pol, AN | 1 |
| Akaike, A; Sato, Y; Tamura, Y; Yokota, T | 1 |
| Becquet, D; Deprez, P; Fache, MP; Faudon, M; Giraud, P; Héry, F; Héry, M | 1 |
| Skeen, GA; Twyman, RE; White, HS | 1 |
| Lee, YH; Leslie, SW; Randall, PK; Spuhler-Phillips, K | 1 |
| Bockaert, J; Lafon-Cazal, M; Marin, P; Quignard, JF | 1 |
| Corner, MA; de Wit, C; Ramakers, GJ; Wolters, PS | 1 |
| Lux, HD; Parsons, CG; Zong, X | 1 |
| Breese, GR; Criswell, HE; Johnson, KB; Mueller, RA | 1 |
| Hara, H; Shimazawa, M; Sukamoto, T; Yokota, K | 1 |
| Ahern, KV; Chan, J; Greenberg, DA; Lustig, HS | 1 |
| Harry, GJ; Kodavanti, PR; Mundy, WR; Tilson, HA | 1 |
| Akaike, A; Honda, Y; Kashii, S; Sasa, M; Tamura, Y; Ujihara, H; Yokota, T | 1 |
| Lee, YH; Leslie, SW; Morris, JL; Randall, PK; Schallert, T; Weaver, MS | 1 |
| Brenneman, DE; Fitzgerald, SC; Summers, RW; von Agoston, D; Wu, XR | 1 |
| Abdel-Hamid, K; Church, J; Fletcher, EJ; MacDonald, JF | 1 |
| Beal, MF; Finklestein, SP; Nozaki, K | 2 |
| Beglan, CL; Bell, JA; London, ED | 1 |
| Numan, M | 1 |
| Aratake, H; Endo, T; Hasegawa, Y; Kitaguchi, N; Morikawa, A; Ogawa, K; Sugimoto, E | 1 |
| Hori, Y; Kanda, K | 1 |
| Herrera-Marschitz, M; Kasakov, L; Nylander, I; Schramm, M; Terenius, L; Vlaskovska, M; You, ZB | 1 |
| Hughes, P; Lee, YH; Leslie, SW; Randoll, L; Spuhler-Phillips, K | 1 |
| Jones, GD; Poston, L | 1 |
| Chakravarthy, B; Durkin, JP; Mealing, G; Morley, P; Small, D; Song, D; Tremblay, R | 1 |
| Galindo, MF; Jordán, J; Miller, RJ | 1 |
| Ho, IK; Lim, DK | 1 |
| Cai, Z; Rhodes, PG | 1 |
| Benford, VJ; Carver, JD; Gilbert-Barness, E; Phelps, C; Valencia, P; Wiener, DA; Wyble, LE | 1 |
| Aliaga, E; Bustos, G; Rage, F; Tapia-Arancibia, L | 1 |
| Bonnot, A; Morin, D; Viala, D | 1 |
| Altmann, L; Gutowski, M; Sveinsson, K; Wiegand, H | 1 |
| Billaud, JN; Elder, JH; Gruol, DL; Parsons, KL; Phillips, TR; Yu, N | 1 |
| Polifka, JE; Shepard, TH | 1 |
| Brent, RL | 1 |
| Aistrup, GL; Marszalec, W; Narahashi, T | 1 |
| Durkin, JP; Hewitt, K; Lesiuk, H; Mealing, G; Morley, P; Tremblay, R | 1 |
| Fryer, HJ; Kalb, RG; Knox, RJ; Strittmatter, SM | 1 |
| Barger, SW | 1 |
| Albers, N; Bettendorf, M; de Zegher, F; Grumbach, MM; Hart, CS; Kaplan, SL | 1 |
| Birkle, DL; Cratty, MS | 1 |
| Murali, SG; Sun, D | 1 |
| Delivoria-Papadopoulos, M; McGowan, JE; Mishra, OP; Numagami, Y; Zanelli, SA | 1 |
| Adams, MM; Flagg, RA; Gore, AC | 1 |
| Chen, Q; Reiner, A; Surmeier, DJ | 1 |
| Standley, CA | 1 |
| Crews, FT; Lauder, JM; Waage, HG; Wilkie, MB | 1 |
| Slamberová, R; Vathy, I; Velísek, L | 1 |
| Aamodt, SM; Colonnese, MT; Constantine-Paton, M; Shi, J; Veras, W | 1 |
| Dubner, R; Hoffman, GE; Murphy, A; Ren, K; Wei1, F | 1 |
| Giaume, C; Glowinski, J; Rouach, N | 1 |
| Andreadis, JD; Barker, JL; Chang, YH; Grant, GM; Hu, Q; Joseph, J; Liu, QY; Ma, W; Maric, D; Stenger, DA | 1 |
| Browning, MD; Costa, ET; Ferreira, VM; Frausto, S; Meyer, DA; Olivera, DS; Savage, DD; Soto, EE; Valenzuela, CF | 1 |
| Merion, AT; Olkowski, JL; Slusher, BS; Thomas, AG; Vornov, JJ | 1 |
| Axer, H; Steinbusch, HW; Teunissen, CE | 1 |
| Slamberová, R; Vathy, I | 1 |
| Inoue, T; Mashimo, T; Shibuta, S; Shimizu, T; Sriranganathan, V; Tomi, K | 1 |
| Darling, S; Huber, J; Park, K; Soliman, KF | 1 |
| Cho, J; Jeong, DY; Kang, BS; Kong, JY; Lee, DU; Lee, KD | 1 |
| Altmann, L; Fastabend, A; Lilienthal, H; Mundy, WR; Ward, TR | 1 |
| Cepeda, C; Hurst, RS; Levine, MS; Shumate, LW | 1 |
| Su, CH; Tao, PL; Wu, YH; Yeh, GC | 1 |
| Kim, HS; Lim, DK | 1 |
| Brewer, GJ; Cady, C; Evans, MS | 1 |
| Comas, T; Hewitt, K; Hogan, M; Monette, R; Morley, P; Paris, J; Tauskela, JS | 1 |
| Desmonts, JM; Evrard, P; Gressens, P; Lagercrantz, H; Laudenbach, V; Mantz, J | 1 |
| Thayer, SA; Wang, GJ | 1 |
| Balakrishnan, R; Numan, M; Numan, MJ; Stack, EC | 1 |
| Farkas, LM; Feyh, P; Hinz, A; Hoffmann, GF; Hörster, F; Kölker, S; Mayatepek, E; Okun, JG; Sauer, S; Unsicker, K | 1 |
| Nardo, L; Soong, Y; Szeto, HH; Walker, D; Wu, D; Young, IR | 1 |
| Meador, KJ | 1 |
| Cho, J; Kim, YH; Kong, JY; Park, CG; Yang, CH | 1 |
| O'Donnell, JM; Suvarna, NU | 1 |
| Macdonald, RL; Rock, DM | 1 |
| Helm, SW; Henzi, V; MacDermott, AB; Reichling, DB | 1 |
| Eigyo, M; Ibii, N; Katsuura, G; Matsushita, A; Shinohara, S; Shintaku, H | 1 |
| Segal, M | 1 |
| Bockaert, J; Desagher, S; Fagni, L; Manzoni, O; Prezeau, L; Sahuquet, A; Sladeczek, F | 1 |
| Chan, J; Greenberg, DA; Lustig, HS | 1 |
| Baimbridge, KG; Church, J; Shacklock, JA | 1 |
| Bridges, RJ; Cotman, CW; Hatalski, CG; Koh, JY | 1 |
| Ham, J; Rickards, C; Scanlon, M | 1 |
| Sprosen, TS; Woodruff, GN | 1 |
| Hablitz, JJ; Mistry, DK | 1 |
| Haesslein, JL; Hunt, PF; Jouanen, A; Massardier, D; Tremblet, AM | 1 |
| Bigalke, H; Lampe, H | 1 |
| Droge, MH; Elbert, K; Hernandez, P | 1 |
| Drian, MJ; Kamenka, JM; Pirat, JL; Privat, A | 1 |
| Erdö, SL; Keilhoff, G | 1 |
| Khaspekov, LG; Lisý, V; Stastný, F; Viktorov, IV | 1 |
| Gross, GW; Lucas, JH; Wang, GF | 1 |
| Mohri, T; Suzuki, R; Takadera, T | 1 |
| Baraban, JM; Murphy, TH | 1 |
| Hunt, A; Patel, AJ; Sanfeliu, C | 1 |
| Albuquerque, EX; Alkondon, M | 1 |
| Brennan, P; Kaba, H; Keverne, EB | 1 |
| Bowe, MA; Martin, D; McNamara, JO; Morrisett, RA; Nadler, JV | 1 |
| Farrington, R; Ingram, CD; Juss, TS; Wakerley, JB | 1 |
| Erdö, SL; Michler, A | 1 |
| Berger, SP; Markwell, MA; Paul, SM | 1 |
| Hershkowitz, N; Rogawski, MA | 1 |
| Drejer, J; Honoré, T; Jensen, LH; Sheardown, MJ; Stidsen, CE | 1 |
| Lee, LR; Pohl, CR; Smith, MS | 1 |
| Jahr, CE; Jessell, TM | 1 |
| Choi, DW; Goldberg, MP; Kim, JP | 1 |
| Hastings, MH; Herbert, J; Roberts, AC | 1 |
4 review(s) available for n-methylaspartate and Pregnancy
| Article | Year |
|---|---|
[Neurological consequences after long-term sedation in the ICU].
Topics: Aging; Anesthetics, General; Animals; Cesarean Section; Conscious Sedation; Critical Care; Excitatory Amino Acid Agonists; Female; Fetal Alcohol Spectrum Disorders; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Premature; Intensive Care Units; N-Methylaspartate; Nervous System Diseases; Neurotoxicity Syndromes; Pregnancy; Primates; Synaptic Transmission; Teratogens | 2012 |
Fetal alcohol syndrome at the cellular level.
Topics: Brain; Female; Fetal Alcohol Spectrum Disorders; Glutamic Acid; Humans; N-Methylaspartate; Pregnancy; Receptors, GABA-A | 2004 |
Neurodevelopmental effects of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Brain; Epilepsy; Epoxy Compounds; Female; Folic Acid; Free Radicals; Humans; Ischemia; Mental Disorders; N-Methylaspartate; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Risk Factors; Teratogens | 2002 |
Kindling, prenatal exposure to ethanol and postnatal development selectively alter responses of hippocampal pyramidal cells to NMDA.
Topics: Animals; Ethanol; Female; Hippocampus; Humans; Kindling, Neurologic; Learning; Maternal-Fetal Exchange; N-Methylaspartate; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate | 1990 |
1 trial(s) available for n-methylaspartate and Pregnancy
| Article | Year |
|---|---|
Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial.
Topics: Analgesics; Anesthetics, Intravenous; Double-Blind Method; Female; Fentanyl; Humans; Hypotension; Ketamine; N-Methylaspartate; Pregnancy; Propofol; Prospective Studies; Receptors, N-Methyl-D-Aspartate | 2022 |
229 other study(ies) available for n-methylaspartate and Pregnancy
| Article | Year |
|---|---|
2-deoxyglucose and β-hydroxybutyrate fail to attenuate seizures in the betamethasone-NMDA model of infantile spasms.
Topics: 3-Hydroxybutyric Acid; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Deoxyglucose; Disease Models, Animal; Female; N-Methylaspartate; Pregnancy; Rats; Seizures; Spasm; Spasms, Infantile | 2022 |
Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autism Spectrum Disorder; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Granulocyte Colony-Stimulating Factor; Hippocampus; Humans; N-Methylaspartate; Neuroprotective Agents; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, AMPA; Receptors, Glutamate; Risperidone; Saline Solution; Valproic Acid | 2022 |
[Long-term neurological outcomes in premature children with excitotoxic brain damage].
Topics: Antibodies; Brain; Brain Injuries; Child; Female; Glutamic Acid; Humans; Infant; Infant, Newborn; Infant, Premature; Lactates; N-Methylaspartate; Pregnancy; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2022 |
Rapamycin Cannot Reduce Seizure Susceptibility in Infantile Rats with Malformations of Cortical Development Lacking mTORC1 Activation.
Topics: Animals; Female; Malformations of Cortical Development; Mechanistic Target of Rapamycin Complex 1; N-Methylaspartate; Pregnancy; Rats; Seizures; Sirolimus; Spasm; TOR Serine-Threonine Kinases | 2022 |
Sex-specific effects of different types of prenatal stress on foetal testosterone levels and NMDA expression in mice.
Topics: Animals; Brain; Corticosterone; Female; Fetus; Humans; Male; Mice; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Stress, Psychological; Testosterone | 2023 |
Insulin-Like Growth Factor-1 Promotes Synaptogenesis Signaling, a Major Dysregulated Pathway in Malformation of Cortical Development, in a Rat Model.
Topics: Animals; Disease Models, Animal; Epilepsy; Female; Humans; Infant; Insulin-Like Growth Factor I; N-Methylaspartate; Pregnancy; Proteomics; Rats; Spasm | 2023 |
Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hippocampus; Humans; Infant, Newborn; MicroRNAs; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 2023 |
Epileptic spasms in infancy: Transferring rat prenatal betamethasone-postnatal NMDA model to mice.
Topics: Adrenocorticotropic Hormone; Animals; Betamethasone; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pregnancy; Rats; Spasms, Infantile | 2023 |
How can methylprednisolone work on epileptic spasms with malformation of cortical development?
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Brain; Disease Models, Animal; Epilepsy; Female; Methylprednisolone; N-Methylaspartate; Neurogenesis; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 2019 |
Serotonin Pretreatment Abolishes Sex-specific NMDA-induced Seizure Behavior in Developing Rats.
Topics: Animals; Female; Male; N-Methylaspartate; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Serotonin; Sex Characteristics | 2021 |
Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Epigenesis, Genetic; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Male; Methylazoxymethanol Acetate; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2017 |
In Utero Exposure to Alcohol Impairs Reactivity of Cerebral Arterioles and Increases Susceptibility of the Brain to Damage Following Ischemia/Reperfusion in Adulthood.
Topics: Acetophenones; Adenosine Diphosphate; Animals; Arterioles; Brain; Enzyme Inhibitors; Ethanol; Excitatory Amino Acid Agonists; Female; Infarction; Infarction, Middle Cerebral Artery; Male; N-Methylaspartate; Nitroglycerin; omega-N-Methylarginine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Reperfusion Injury | 2019 |
AQB-565 shows promise in preclinical testing in the model of epileptic spasms during infancy: Head-to-head comparison with ACTH.
Topics: Adrenocorticotropic Hormone; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Female; Humans; Infant; Male; Melanocyte-Stimulating Hormones; N-Methylaspartate; Peptides; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Spasms, Infantile; Treatment Outcome | 2019 |
Developmental docosahexaenoic and arachidonic acid supplementation improves adult learning and increases resistance against excitotoxicity in the brain.
Topics: Animals; Arachidonic Acid; Dietary Supplements; Docosahexaenoic Acids; Drug Evaluation, Preclinical; Entorhinal Cortex; Female; Maze Learning; Memory; Memory Disorders; Microglia; N-Methylaspartate; Pregnancy; Rats; Rats, Wistar | 2013 |
Effect of neuroserpin in a neonatal hypoxic-ischemic injury model ex vivo.
Topics: Animals; Animals, Newborn; Cell Survival; Dizocilpine Maleate; Female; Hypoxia-Ischemia, Brain; Immunohistochemistry; N-Methylaspartate; Neurons; Neuropeptides; Neuroprotective Agents; Neuroserpin; Pregnancy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Serpins; Tissue Plasminogen Activator | 2012 |
Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries.
Topics: Animals; Brain; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Fluorodeoxyglucose F18; Green Fluorescent Proteins; L-Lactate Dehydrogenase; Male; Mice; Mutation; N-Methylaspartate; Nervous System Diseases; Neurons; Nuclear Localization Signals; Peptides; Pregnancy; Protein Transport; PTEN Phosphohydrolase; Radionuclide Imaging; Rats; Rats, Sprague-Dawley | 2013 |
Novel analogues of chlormethiazole are neuroprotective in four cellular models of neurodegeneration by a mechanism with variable dependence on GABA(A) receptor potentiation.
Topics: Animals; Biological Availability; Brain; Calcium; Cell Hypoxia; Chlormethiazole; Chromatography, High Pressure Liquid; Excitatory Amino Acid Agonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glucose; Glutamic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Oocytes; Pregnancy; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Xenopus laevis | 2014 |
Full-gestational exposure to nicotine and ethanol augments nicotine self-administration by altering ventral tegmental dopaminergic function due to NMDA receptors in adolescent rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blotting, Western; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Dopaminergic Neurons; Electrochemistry; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Microinjections; N-Methylaspartate; Nicotine; Nicotinic Agonists; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Self Administration; Ventral Tegmental Area | 2014 |
Progressive brain damage, synaptic reorganization and NMDA activation in a model of epileptogenic cortical dysplasia.
Topics: Animals; Atrophy; Cerebral Cortex; Disease Models, Animal; Epilepsies, Partial; Female; Hippocampus; Malformations of Cortical Development; N-Methylaspartate; Neocortex; Pregnancy; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synapses | 2014 |
Erythropoietin attenuates loss of potassium chloride co-transporters following prenatal brain injury.
Topics: Age Factors; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Carbazoles; Enzyme Inhibitors; Erythropoietin; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Developmental; Hippocampus; In Vitro Techniques; Indole Alkaloids; Ischemic Attack, Transient; K Cl- Cotransporters; Male; N-Methylaspartate; Neuroprotective Agents; Pregnancy; Rats; Rats, Sprague-Dawley; Symporters | 2014 |
Proteomic analysis on infantile spasm and prenatal stress.
Topics: 14-3-3 Proteins; Animals; Cofilin 1; Computational Biology; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Humans; Infant; Male; Molecular Chaperones; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Interaction Maps; Proteomics; Rats; Rats, Wistar; Spasms, Infantile; Stress, Psychological; Two-Dimensional Difference Gel Electrophoresis | 2014 |
Prenatal nicotine is associated with reduced AMPA and NMDA receptor-mediated rises in calcium within the laterodorsal tegmentum: a pontine nucleus involved in addiction processes.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Female; Glutamic Acid; Humans; Mice; Motivation; N-Methylaspartate; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Substance-Related Disorders; Tegmentum Mesencephali | 2015 |
Aberrant NMDA-dependent LTD after perinatal ethanol exposure in young adult rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Central Nervous System Depressants; Electric Stimulation; Ethanol; Excitatory Amino Acid Agents; Female; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; N-Methylaspartate; Patch-Clamp Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 2015 |
IGF-1-Involved Negative Feedback of NR2B NMDA Subunits Protects Cultured Hippocampal Neurons Against NMDA-Induced Excitotoxicity.
Topics: Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; Insulin-Like Growth Factor I; N-Methylaspartate; Neurons; Pregnancy; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2017 |
Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation.
Topics: Animals; Antidepressive Agents; Cells, Cultured; Cerebral Cortex; Cysteine; Depression; Disease Models, Animal; Embryo, Mammalian; Exploratory Behavior; Female; Gene Expression Regulation; HEK293 Cells; Humans; Ketamine; Male; Mice, Inbred C57BL; Mice, Knockout; Monomeric GTP-Binding Proteins; N-Methylaspartate; Neurons; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pregnancy; Proteolysis; Ras Homolog Enriched in Brain Protein; S-Nitrosothiols; Signal Transduction; Swimming; Time Factors; TOR Serine-Threonine Kinases | 2016 |
Enhanced long-term potentiation in mature rats in a model of epileptic spasms with betamethasone-priming and postnatal N-methyl-D-aspartate administration.
Topics: Age Factors; Animals; Animals, Newborn; Betamethasone; Disease Models, Animal; Epilepsy; Female; Long-Term Potentiation; Male; N-Methylaspartate; Organ Culture Techniques; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2016 |
The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Galanin; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Lipopeptides; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Neurotransmitter Agents; Organ Culture Techniques; Pregnancy; Time Factors; Vitamin K | 2016 |
Increased precipitation of spasms in an animal model of infantile spasms by prenatal stress exposure.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Cold Temperature; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Hormones; Humans; Infant; Infant, Newborn; Male; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Neurotransmitter; Spasms, Infantile; Stress, Psychological; Swimming | 2016 |
The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation.
Topics: 2-Amino-5-phosphonovalerate; Amyloid beta-Peptides; Animals; Cell Membrane; Cells, Cultured; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; HEK293 Cells; Hippocampus; Humans; Membrane Potentials; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Pregnancy; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate | 2016 |
Distance-dependent gradient in NMDAR-driven spine calcium signals along tapering dendrites.
Topics: Animals; Calcium; Calcium Signaling; Dendritic Spines; Embryo, Mammalian; Female; Gene Expression; Hippocampus; Mice; Mice, Inbred C57BL; Microscopy, Electron; Microtomy; N-Methylaspartate; Neuronal Plasticity; Pregnancy; Primary Cell Culture; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 2017 |
Differential neuroprotection and risk for bleeding from activated protein C with varying degrees of anticoagulant activity.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Hemorrhage; Endothelial Cells; Excitatory Amino Acid Agonists; Female; Fibrinolytic Agents; Humans; Infarction, Middle Cerebral Artery; Mice; Mice, Inbred C57BL; Mutation; N-Acetylneuraminic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Partial Thromboplastin Time; Polysaccharides; Pregnancy; Protein C; Recombinant Proteins; Risk | 2009 |
Perinatal maternal fat intake affects metabolism and hippocampal function in the offspring: a potential role for leptin.
Topics: Animals; Dietary Fats; Female; Hippocampus; Leptin; Maternal Exposure; Models, Biological; N-Methylaspartate; Pregnancy; Rats; Receptors, Glucocorticoid | 2008 |
Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Cognition; Female; Fetus; Homocysteine; Hyperhomocysteinemia; Maze Learning; N-Methylaspartate; Oxidative Stress; Pregnancy; Rats; Reactive Oxygen Species; Superoxide Dismutase | 2008 |
Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity.
Topics: Analysis of Variance; Animals; Antibodies; Anticoagulants; Apoptosis; Brain; Caspase 3; Caspase 9; Cells, Cultured; Embryo, Mammalian; Endothelial Cells; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Glucose; Hemoglobins; Humans; Hypoxia; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; N-Methylaspartate; Neurons; Neuroprotective Agents; Pregnancy; Protein C; Receptors, Proteinase-Activated; Time Factors; Tumor Suppressor Protein p53 | 2009 |
17beta-estradiol-mediated neuroprotection and ERK activation require a pertussis toxin-sensitive mechanism involving GRK2 and beta-arrestin-1.
Topics: Animals; Animals, Newborn; Arrestins; beta-Arrestin 1; beta-Arrestins; Biotin; Brain; Cell Culture Techniques; Cell Death; Cells, Cultured; Cholera Toxin; Drug Interactions; Enzyme Activation; Estradiol; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Female; G-Protein-Coupled Receptor Kinase 2; Gangliosidosis, GM1; Gene Expression Regulation; L-Lactate Dehydrogenase; Membrane Microdomains; Microtubule-Associated Proteins; N-Methylaspartate; Neurons; Neuroprotective Agents; Pertussis Toxin; Pregnancy; Protein Transport; Rats; Rats, Sprague-Dawley; RNA, Small Interfering | 2009 |
Protease-activated receptor 1-dependent neuronal damage involves NMDA receptor function.
Topics: Analysis of Variance; Animals; Brain Injuries; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanidines; Injections, Intraventricular; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Oligopeptides; Pregnancy; Rats; Receptor, PAR-1; Receptors, N-Methyl-D-Aspartate | 2009 |
Effects of a single postnatal methamphetamine administration on NMDA-induced seizures are sex- and prenatal exposure-specific.
Topics: Animals; Central Nervous System Stimulants; Drug Administration Schedule; Estrous Cycle; Excitatory Amino Acid Agonists; Female; Male; Methamphetamine; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures; Sex Factors; Stereotyped Behavior; Time Factors | 2009 |
Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.
Topics: Action Potentials; Animals; Benzoxazines; Biophysics; Calcium; Calcium Channel Blockers; Cerebral Cortex; Corpus Striatum; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Glycine; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mice; Mice, Knockout; Morpholines; N-Methylaspartate; Naphthalenes; Neurons; Phenylacetates; Piperidines; Pregnancy; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Adenosine A2; Synapses; Triazines; Triazoles | 2009 |
Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.
Topics: Animals; Anthraquinones; Cell Line, Tumor; Cells, Cultured; Cloning, Molecular; Dansyl Compounds; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Humans; Mice; N-Methylaspartate; Neuroblastoma; Neurons; Neuroprotective Agents; Oocytes; Patch-Clamp Techniques; Polyamines; Pregnancy; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Seizures; Spermine; Tosyl Compounds; Xenopus laevis | 2009 |
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone | 2009 |
Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA-induced BDNF expression in cortical neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Cerebral Cortex; Chromatin Immunoprecipitation; CREB-Binding Protein; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation; Inhibitory Postsynaptic Potentials; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pregnancy; Promoter Regions, Genetic; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Receptors, N-Methyl-D-Aspartate; RNA, Small Interfering; Transfection | 2009 |
Neuregulin beta1 enhances peak glutamate-induced intracellular calcium levels through endoplasmic reticulum calcium release in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Chemistry; Calcium; Calcium Signaling; Cells, Cultured; Endoplasmic Reticulum; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Inositol 1,4,5-Trisphosphate Receptors; N-Methylaspartate; Neuregulin-1; Neurons; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Ryanodine; Ryanodine Receptor Calcium Release Channel; Second Messenger Systems | 2009 |
Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved.
Topics: Animals; Cerebellum; Cyclic GMP; Discrimination, Psychological; Environmental Pollutants; Extracellular Space; Female; gamma-Aminobutyric Acid; Glutamic Acid; Learning; Male; Maternal Exposure; Maze Learning; N-Methylaspartate; Polychlorinated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Rats; Receptors, N-Methyl-D-Aspartate; Sex Factors | 2010 |
Interaction of PGHS-2 and glutamatergic mechanisms controlling the ovine fetal hypothalamus-pituitary-adrenal axis.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; D-Aspartic Acid; Female; Fetus; Hydrocortisone; Hypothalamus; Isoenzymes; N-Methylaspartate; Neurosecretory Systems; Parturition; Pituitary-Adrenal System; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Resveratrol; Sheep; Stilbenes; Sulfonamides | 2010 |
Gamma band unit activity and population responses in the pedunculopontine nucleus.
Topics: Action Potentials; Animals; Carbachol; Electroencephalography; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Female; Kainic Acid; Membrane Potentials; Muscarinic Agonists; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pedunculopontine Tegmental Nucleus; Potassium Channel Blockers; Potassium Channels; Pregnancy; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Theta Rhythm | 2010 |
Activity-dependent alpha-cleavage of nectin-1 is mediated by a disintegrin and metalloprotease 10 (ADAM10).
Topics: ADAM Proteins; ADAM10 Protein; Amyloid Precursor Protein Secretases; Animals; Brain; Calcium; Calmodulin; Cell Adhesion Molecules; Cell Line; Female; Gene Expression Regulation, Enzymologic; Humans; Membrane Proteins; Mice; N-Methylaspartate; Nectins; Neurons; Pregnancy; Protein Structure, Tertiary; Rats; Receptors, N-Methyl-D-Aspartate | 2010 |
Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective.
Topics: Animals; Astrocytes; Cell Death; Cells, Cultured; Coculture Techniques; Connexin 43; Cytokines; Female; Fluorescent Dyes; Gap Junctions; Interleukin-1beta; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Pregnancy; Tumor Necrosis Factor-alpha | 2010 |
Curcumin protects against NMDA-induced toxicity: a possible role for NR2A subunit.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Blotting, Western; Calcium; Cells, Cultured; Curcumin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; Immunohistochemistry; In Situ Nick-End Labeling; Kainic Acid; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Retina; Time Factors | 2011 |
Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures.
Topics: Animals; Caspase 3; Cell Survival; Cells, Cultured; Cerebral Cortex; DNA-Binding Proteins; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation; Granulins; Humans; Hydrogen Peroxide; Indoles; Intercellular Signaling Peptides and Proteins; Mice; N-Methylaspartate; Neurons; Oxidants; Pregnancy; Progranulins; Protein Transport; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transfection | 2010 |
Progesterone inhibits estrogen-mediated neuroprotection against excitotoxicity by down-regulating estrogen receptor-β.
Topics: Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Cell Survival; Down-Regulation; Drug Interactions; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Excitatory Amino Acid Agonists; Female; Heterocyclic Compounds; Hippocampus; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Nitriles; Organ Culture Techniques; Organophosphorus Compounds; Phenols; Pregnancy; Progesterone; Progestins; Propionates; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Statistics, Nonparametric | 2010 |
Increased seizure susceptibility induced by prenatal methamphetamine exposure in adult female rats is not affected by early postnatal cross-fostering.
Topics: Animals; Bicuculline; Disease Susceptibility; Female; Maternal Behavior; Methamphetamine; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures | 2011 |
Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cell Survival; Cells, Cultured; Cerebral Cortex; Chemokine CCL5; Culture Media, Conditioned; Curcumin; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Agonists; Female; Mitogen-Activated Protein Kinases; N-Methylaspartate; Neurons; Phosphatidylinositol 3-Kinases; Pregnancy; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Signal Transduction; Transfection; Up-Regulation | 2011 |
Responses of developing pedunculopontine neurons to glutamate receptor agonists.
Topics: Animals; Animals, Newborn; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Kainic Acid; Models, Animal; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pedunculopontine Tegmental Nucleus; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sleep, REM | 2011 |
Effect of brain-derived neurotrophic factor on activity-regulated cytoskeleton-associated protein gene expression in primary frontal cortical neurons. Comparison with NMDA and AMPA.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Female; Frontal Lobe; Gene Expression Regulation; Humans; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Time | 2011 |
Validation of the rat model of cryptogenic infantile spasms.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Disease Models, Animal; Electroencephalography; Exploratory Behavior; Female; GABA Agents; Glucocorticoids; Humans; Infant, Newborn; Male; Maze Learning; Methylprednisolone; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spasms, Infantile; Time Factors; Vigabatrin | 2011 |
Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero.
Topics: Abnormalities, Drug-Induced; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Female; Male; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Time Factors; Valproic Acid | 2011 |
Neuron-specific effects of interleukin-1β are mediated by a novel isoform of the IL-1 receptor accessory protein.
Topics: Analysis of Variance; Animals; Astrocytes; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activation; Female; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Interleukin-1 Receptor Accessory Protein; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pregnancy; Protein Isoforms; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors; Transfection | 2011 |
Calpains are downstream effectors of bax-dependent excitotoxic apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Calpain; Cell Line, Tumor; Cells, Cultured; Dipeptides; Excitatory Amino Acid Agonists; Female; Hippocampus; Humans; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Organ Culture Techniques; Pregnancy | 2012 |
Prenatal stress exposure hypothesis for infantile spasms.
Topics: Animals; Case-Control Studies; Cold Temperature; Female; Humans; Infant, Newborn; Models, Biological; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spasms, Infantile; Stress, Physiological | 2012 |
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons.
Topics: 4-Aminopyridine; Analysis of Variance; Animals; Bicuculline; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Corpus Striatum; CREB-Binding Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Agents; Female; GABA-A Receptor Antagonists; Glutamate Decarboxylase; Glycine Agents; Luminescent Proteins; Microfluidic Analytical Techniques; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nifedipine; Patch-Clamp Techniques; Potassium Channel Blockers; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium Channel Blockers; Strychnine; Synapses; Tetrodotoxin; Transfection; Vesicular Glutamate Transport Protein 1 | 2012 |
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome.
Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cell Death; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; MAP Kinase Signaling System; Methyl-CpG-Binding Protein 2; Mice; Motor Activity; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Propylene Glycols; Receptors, Lysosphingolipid; Rett Syndrome; Sphingosine | 2012 |
Proteomic analysis of adrenocorticotropic hormone treatment of an infantile spasm model induced by N-methyl-D-aspartic acid and prenatal stress.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Infant, Newborn; N-Methylaspartate; Pregnancy; Proteome; Proteomics; Spasms, Infantile; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stress, Physiological | 2012 |
Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.
Topics: Animals; Calcium Signaling; Cells, Cultured; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Female; Glycine; Image Processing, Computer-Assisted; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Neurosecretory Systems; Osmolar Concentration; Pregnancy; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Supraoptic Nucleus | 2002 |
Receptor-activated calcium signals in tangentially migrating cortical cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Calcium; Calcium Signaling; Cell Movement; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA-A Receptor Agonists; Kainic Acid; Male; Muscimol; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Tetrodotoxin | 2002 |
Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture.
Topics: Apoptosis; Asphyxia Neonatorum; Benzimidazoles; Carbocyanines; Cell Count; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Humans; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Infant, Newborn; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Pregnancy; Pregnanolone; Progesterone; Tumor Cells, Cultured | 2002 |
Stimulation of N-methyl-D-aspartate (NMDA) receptors inhibits neuronal migration in embryonic cerebral cortex: a tissue culture study.
Topics: Animals; Autoradiography; Cell Movement; Cerebellum; Cerebral Cortex; Culture Techniques; Excitatory Amino Acid Agonists; Female; Ibotenic Acid; Mitosis; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Stem Cells; Thymidine | 2002 |
Functional alteration by NMDA antagonist: effects of L-Dopa, neuroleptics drug and postnatal administration.
Topics: Age Factors; Animals; Animals, Newborn; Antiparkinson Agents; Antipsychotic Agents; Excitatory Amino Acid Antagonists; Female; Humans; Levodopa; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Oxidopamine; Parkinsonian Disorders; Pregnancy; Rats; Rats, Sprague-Dawley; Sympatholytics | 2002 |
Chronic NMDA receptor blockade from birth delays the maturation of NMDA currents, but does not affect AMPA/kainate currents.
Topics: Adaptation, Physiological; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain; Calcium; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Kainic Acid; N-Methylaspartate; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synapses | 2003 |
Protection of cortical neurons against oxygen-glucose deprivation and N-methyl-D-aspartate by DIDS and SITS.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anaerobiosis; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Glucose; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Oxygen; Pregnancy; Rats; Rats, Sprague-Dawley | 2003 |
Glutamate promotes proliferation of striatal neuronal progenitors by an NMDA receptor-mediated mechanism.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Division; Cells, Cultured; Corpus Striatum; Drug Administration Schedule; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Image Cytometry; Injections, Intraperitoneal; Male; Maternal-Fetal Exchange; N-Methylaspartate; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stem Cells | 2003 |
Prevention of eclampsia.
Topics: Calcium Channel Blockers; Cerebrovascular Circulation; Eclampsia; Female; Humans; Magnesium Sulfate; N-Methylaspartate; Pregnancy; Seizures | 2003 |
Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats.
Topics: Acetylcholinesterase; Animals; Axons; Basal Nucleus of Meynert; Choline O-Acetyltransferase; Cholinergic Fibers; Dendrites; Docosahexaenoic Acids; Drug Resistance; Female; Food, Formulated; Membrane Lipids; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Rats; Rats, Wistar; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Treatment Outcome | 2003 |
Protective effects of fangchinoline and tetrandrine on hydrogen peroxide-induced oxidative neuronal cell damage in cultured rat cerebellar granule cells.
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium; Cell Death; Cerebellum; Cytoplasmic Granules; Female; Hydrogen Peroxide; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Roots; Pregnancy; Rats; Rats, Sprague-Dawley; Stephania tetrandra; Verapamil | 2003 |
Neuroprotective activity of antazoline against neuronal damage induced by limbic status epilepticus.
Topics: Animals; Animals, Newborn; Antazoline; Cell Count; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Conductivity; Electroencephalography; Excitatory Amino Acid Agonists; Female; Hippocampus; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscarinic Agonists; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pilocarpine; Pregnancy; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors; Trauma, Nervous System | 2003 |
NMDA-induced apoptosis in the developing rat brain.
Topics: Animals; Animals, Newborn; Apoptosis; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; In Situ Nick-End Labeling; Injections, Intraperitoneal; Maternal Exposure; N-Methylaspartate; Neurons; Organogenesis; Pregnancy; Rats | 2003 |
Oral-motor patterns of rhythmic trigeminal activity generated in fetal rat brainstem in vitro.
Topics: Action Potentials; Animals; Bicuculline; Brain Stem; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; GABA Antagonists; In Vitro Techniques; Male; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Trigeminal Nuclei | 2003 |
The neuroprotective effect of ONO-1714 on NMDA-mediated cytotoxicity in vitro.
Topics: Amidines; Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Female; Heterocyclic Compounds, 2-Ring; N-Methylaspartate; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar | 2003 |
Hyperactivity following postnatal NMDA antagonist treatment: reversal by D-amphetamine.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Depressants; Central Nervous System Stimulants; Dextroamphetamine; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Female; Fluoresceins; Fluorescent Dyes; Habituation, Psychophysiologic; Hyperkinesis; Ketamine; Male; Mice; Motor Activity; N-Methylaspartate; Organic Chemicals; Pregnancy; Weight Gain | 2003 |
Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation.
Topics: Animals; Choline; Choline Deficiency; Cues; Cyclic AMP Response Element-Binding Protein; Female; Glutamic Acid; Hippocampus; Humans; MAP Kinase Signaling System; Maze Learning; Memory Disorders; Mitogen-Activated Protein Kinases; N-Methylaspartate; Phosphorylation; Potassium; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Protein Processing, Post-Translational; Rats; Reaction Time; Spatial Behavior | 2004 |
Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Flavanones; Free Radical Scavengers; Lipid Peroxidation; Male; N-Methylaspartate; Neurons; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley | 2004 |
Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons.
Topics: Adenosine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Female; Glutamic Acid; Intracellular Space; Male; Membrane Potentials; Models, Neurological; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Pregnancy; Prosencephalon; Purinones; Rats; Rats, Sprague-Dawley; Thionucleotides | 2004 |
Permissive role of adenosine A2A receptors on metabotropic glutamate receptor 5 (mGluR5)-mediated effects in the striatum.
Topics: Adenosine; Animals; Carbazoles; Cells, Cultured; Corpus Striatum; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Indoles; Male; Membrane Potentials; N-Methylaspartate; Phenethylamines; Phenylacetates; Pregnancy; Purinergic P1 Receptor Agonists; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Triazines; Triazoles | 2004 |
Factors accounting for perinatal occurrence of pulsatile gonadotropin-releasing hormone secretion in vitro in rats.
Topics: Animals; Dinoprostone; Embryo, Mammalian; Feedback, Physiological; Female; GABA Antagonists; Glutamates; Gonadotropin-Releasing Hormone; In Vitro Techniques; Labor, Obstetric; Male; N-Methylaspartate; Oxytocin; Pregnancy; Pyridazines; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2005 |
Disinhibition of maternal behavior following neurotoxic lesions of the hypothalamus in primigravid rats.
Topics: Animals; Dorsomedial Hypothalamic Nucleus; Female; Gravidity; Hypothalamus; Maternal Behavior; N-Methylaspartate; Nerve Net; Pregnancy; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus | 2004 |
Brevetoxin augments NMDA receptor signaling in murine neocortical neurons.
Topics: Animals; Calcium; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; MAP Kinase Signaling System; Marine Toxins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; N-Methylaspartate; Neocortex; Neurons; Oxocins; Phosphorylation; Pregnancy; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Sodium; Sodium Channels; src-Family Kinases; Tyrosine | 2005 |
Adenosine protects cultured retinal neurons against NMDA-induced cell death through A1 receptors.
Topics: Adenosine; Animals; Cell Death; Cell Survival; Cells, Cultured; Coloring Agents; Cytoprotection; Excitatory Amino Acid Agonists; Female; N-Methylaspartate; Neuroglia; Pregnancy; Rats; Rats, Wistar; Receptor, Adenosine A1; Retina; Trypan Blue | 2004 |
Effects of propofol on N-methyl-D-aspartate receptor-mediated calcium increase in cultured rat cerebrocortical neurons.
Topics: Anesthetics, Intravenous; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cytosol; Excitatory Amino Acid Agonists; Female; Fluorescent Dyes; Microscopy, Confocal; N-Methylaspartate; Neurons; Organic Chemicals; Pregnancy; Propofol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2005 |
Inhibition of apoptosis-inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal neurons.
Topics: Animals; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Gene Expression Regulation; Hepatocyte Growth Factor; Hippocampus; Humans; Immunohistochemistry; Immunoprecipitation; N-Methylaspartate; Neurons; Neurotoxins; Phosphopyruvate Hydratase; Poly Adenosine Diphosphate Ribose; Pregnancy; Protein Transport; Proto-Oncogene Proteins c-met; Rats; Recombinant Proteins; Time Factors | 2005 |
Seizure susceptibility in prenatally methamphetamine-exposed adult female rats.
Topics: Animals; Bicuculline; Central Nervous System Stimulants; Disease Susceptibility; Estrous Cycle; Excitatory Amino Acid Agonists; Female; GABA Antagonists; Methamphetamine; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures | 2005 |
Occurrence of bicuculline-, NMDA- and kainic acid-induced seizures in prenatally methamphetamine-exposed adult male rats.
Topics: Animals; Bicuculline; Central Nervous System Stimulants; Excitatory Amino Acid Agonists; Female; GABA Antagonists; Kainic Acid; Male; Methamphetamine; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Seizures | 2005 |
Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Bicuculline; Blotting, Western; Colforsin; Disks Large Homolog 4 Protein; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Fluorescent Antibody Technique; GABA Antagonists; Glycine; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phenethylamines; Phenylacetates; Pregnancy; Presynaptic Terminals; Pyridines; Qa-SNARE Proteins; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Synaptophysin; Vesicular Glutamate Transport Protein 1 | 2005 |
Reversal of neuronal migration in a mouse model of fetal alcohol syndrome by controlling second-messenger signalings.
Topics: Animals; Animals, Newborn; Caffeine; Cell Migration Inhibition; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Mice; N-Methylaspartate; Neurons; Pregnancy; Second Messenger Systems | 2006 |
A role for the periaqueductal gray in switching adaptive behavioral responses.
Topics: Adaptation, Psychological; Animals; Animals, Newborn; Behavior, Animal; Female; Functional Laterality; Inhibition, Psychological; Male; Maternal Behavior; Morphine; N-Methylaspartate; Narcotics; Periaqueductal Gray; Predatory Behavior; Pregnancy; Prenatal Exposure Delayed Effects; Rats | 2006 |
Pharmacologically induced calcium oscillations protect neurons from increases in cytosolic calcium after trauma.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Animals; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Signaling; Cytosol; Drug Combinations; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Antagonists; Gene Expression Regulation; N-Methylaspartate; Neurons; Nimodipine; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Tetrodotoxin; Thiazoles; Thiazolidines | 2006 |
[Protective effect of maternal immunoglobulin G against NMDA-induced neurotoxicity on hippocampus neurons].
Topics: Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, Cultured; Excitatory Amino Acid Agonists; Female; Hippocampus; Immunity, Maternally-Acquired; Immunoglobulin G; Immunologic Factors; L-Lactate Dehydrogenase; Male; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar | 2006 |
Acute exposure to methylmercury at two developmental windows: focus on neurobehavioral and neurochemical effects in rat offspring.
Topics: Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain Chemistry; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Glutamic Acid; Inhibition, Psychological; Male; Maze Learning; Methylmercury Compounds; Motor Activity; N-Methylaspartate; Neurons; Potassium Chloride; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reflex, Startle; Rotarod Performance Test; Time Factors | 2006 |
Motherhood-induced memory improvement persists across lifespan in rats but is abolished by a gestational stress.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Electrophysiology; Female; Hippocampus; Learning; Life Expectancy; Male; Memory; Mothers; N-Methylaspartate; Neuronal Plasticity; Pregnancy; Rats; Rats, Wistar; Stress, Psychological | 2006 |
Long lasting effects of prenatal exposure to deltamethrin on cerebral and hepatic cytochrome P450s and behavioral activity in rat offspring.
Topics: Animals; Behavior, Animal; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Insecticides; Liver; Male; Maternal Exposure; N-Methylaspartate; Nitriles; Pregnancy; Pyrethrins; Rats; Rats, Wistar; Telencephalon | 2006 |
An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax.
Topics: Animals; Apoptosis; Axons; bcl-2-Associated X Protein; Cell Count; Cell Differentiation; Cell Proliferation; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Genes, bcl-2; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Motor Neurons; N-Methylaspartate; Neuregulin-1; Pregnancy; Prenatal Exposure Delayed Effects; Schwann Cells | 2006 |
Post-pubertal disruption of medial prefrontal cortical dopamine-glutamate interactions in a developmental animal model of schizophrenia.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Disease Models, Animal; Dopamine; Dopamine Agonists; Electrophysiology; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Schizophrenia | 2007 |
Prenatal exposure to polybrominated diphenylether 99 enhances the function of the glutamate-nitric oxide-cGMP pathway in brain in vivo and in cultured neurons.
Topics: Age Factors; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; Drug Interactions; Female; Gene Expression Regulation; Glutamic Acid; Halogenated Diphenyl Ethers; N-Methylaspartate; Neurons; Nitric Oxide; Penicillamine; Phenyl Ethers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Signal Transduction | 2007 |
Model of infantile spasms induced by N-methyl-D-aspartic acid in prenatally impaired brain.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Brain; Deoxyglucose; Disease Models, Animal; Drug Administration Schedule; Drug Synergism; Electroencephalography; Female; Fetus; Gestational Age; Glucocorticoids; Humans; Immunohistochemistry; Infant, Newborn; N-Methylaspartate; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Spasms, Infantile | 2007 |
Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channels.
Topics: Aging; Animals; Calcium; Calcium Channels, L-Type; Cell Survival; Cells, Cultured; Dizocilpine Maleate; Embryo, Mammalian; Female; Gene Expression; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2007 |
Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures.
Topics: Anastrozole; Androgen Antagonists; Androgens; Animals; Aromatase Inhibitors; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Flutamide; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Nitriles; Pregnancy; Testosterone; Triazoles | 2007 |
RGD domains neuroprotect the immature brain by a glial-dependent mechanism.
Topics: Animals; Astrocytes; Behavior, Animal; Brain; Brain Chemistry; Cell Count; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Data Interpretation, Statistical; Densitometry; Excitatory Amino Acids; Female; Immunohistochemistry; Microglia; N-Methylaspartate; Nerve Degeneration; Neuroglia; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neutrophil Infiltration; Oligopeptides; Pregnancy; Rats; Rats, Long-Evans | 2007 |
Interferon-beta is neuroprotective against the toxicity induced by activated microglia.
Topics: Animals; Cells, Cultured; Coculture Techniques; Cytokines; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Interferon Type I; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microglia; Molsidomine; N-Methylaspartate; Neurons; Neuroprotective Agents; Nitric Oxide; Peroxynitrous Acid; Pregnancy; Recombinant Proteins; Superoxides; Tumor Necrosis Factor-alpha | 2007 |
Role of nitric oxide in cerebrovascular reactivity to NMDA and hypercapnia during prenatal development in sheep.
Topics: Age Factors; Analysis of Variance; Animals; Blood Pressure; Cerebrovascular Circulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hypercapnia; Laser-Doppler Flowmetry; N-Methylaspartate; Nitric Oxide; Nitroarginine; Pregnancy; Prenatal Exposure Delayed Effects; Regional Blood Flow; Sheep | 2008 |
A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced neuronal cell death.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Caspase 3; Cell Death; Cell Survival; Chondroitin Sulfates; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neocortex; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Polyelectrolytes; Polymers; Pregnancy; Rats; Rats, Sprague-Dawley; Tyrosine | 2008 |
Transplantation of cells from eye-like structures differentiated from embryonic stem cells in vitro and in vivo regeneration of retinal ganglion-like cells.
Topics: Animals; Biomarkers; Cell Culture Techniques; Cell Differentiation; Cell Movement; Embryonic Stem Cells; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Female; Fluorescent Antibody Technique, Indirect; Green Fluorescent Proteins; Immunoenzyme Techniques; In Situ Nick-End Labeling; Lens, Crystalline; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pregnancy; Regeneration; Retina; Retinal Ganglion Cells; Stem Cell Transplantation; Stem Cells; Vitreous Body | 2008 |
Reduced calcium-dependent mitochondrial damage underlies the reduced vulnerability of excitotoxicity-tolerant hippocampal neurons.
Topics: Adaptation, Physiological; Animals; Calcium; Calcium Phosphates; Cell Survival; Cells, Cultured; Cytosol; Down-Regulation; Excitatory Amino Acid Agonists; Female; Hippocampus; Ischemic Preconditioning; Mitochondria; N-Methylaspartate; Neurons; Neurotoxins; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate | 2008 |
Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences.
Topics: Animals; Animals, Newborn; Dendritic Spines; Dizocilpine Maleate; Drug Interactions; Estradiol; Excitatory Amino Acid Antagonists; Female; Hypothalamus; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Pregnancy; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Silver Staining | 2008 |
NMDA prevents alcohol-induced neuronal cell death of cerebellar granule cells in culture.
Topics: Animals; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Gestational Age; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
Continuous exposure of cultured rat cerebellar macroneurons to ethanol-depressed NMDA and KCl-stimulated elevations of intracellular calcium.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Cerebellum; Embryo, Mammalian; Ethanol; Female; Intracellular Fluid; Male; Membrane Potentials; Microscopy, Phase-Contrast; N-Methylaspartate; Neurons; Potassium Chloride; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate | 1995 |
Assessment of primary neuronal culture as a model for soman-induced neurotoxicity and effectiveness of memantine as a neuroprotective drug.
Topics: Acetylcholine; Animals; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Injections, Subcutaneous; L-Lactate Dehydrogenase; Lethal Dose 50; Male; Memantine; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Seizures; Soman | 1995 |
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, Cultured; Cycloleucine; Female; Glutamates; Glutamic Acid; Ion Channel Gating; Kainic Acid; Kinetics; Lanthanum; N-Methylaspartate; Neurons; Neurotoxins; Photometry; Potassium; Pregnancy; Presynaptic Terminals; Quisqualic Acid; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1993 |
Involvement of granule, basket and stellate neurons but not Purkinje or Golgi cells in cerebellar cGMP increases in vivo.
Topics: Amino Acid Oxidoreductases; Amino Acids; Animals; Cerebellum; Cyclic GMP; Cytoplasmic Granules; Female; Golgi Apparatus; Harmaline; Immunohistochemistry; Methylazoxymethanol Acetate; Mice; Mice, Neurologic Mutants; N-Methylaspartate; Neurons; Nitric Oxide Synthase; Pregnancy; Purkinje Cells | 1994 |
Novel adamantane derivatives act as blockers of open ligand-gated channels and as anticonvulsants.
Topics: Adamantane; Animals; Anticonvulsants; Cholinergic Fibers; Electrophysiology; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kinetics; Male; Mice; N-Methylaspartate; Neuromuscular Junction; Pregnancy; Quaternary Ammonium Compounds; Rana temporaria; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 1995 |
Modulation by sigma ligands of intracellular free Ca++ mobilization by N-methyl-D-aspartate in primary culture of rat frontal cortical neurons.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium; Cells, Cultured; Cerebral Cortex; Dopamine D2 Receptor Antagonists; Drug Interactions; Female; Glycine; Haloperidol; Intracellular Fluid; Ligands; Magnesium; Microscopy, Fluorescence; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1995 |
Analysis of glutamate receptors in primary cultured neurons from fetal rat forebrain.
Topics: Animals; Animals, Newborn; Binding, Competitive; Cell Membrane; Cells, Cultured; Embryo, Mammalian; Female; Fetus; Glutamic Acid; Kinetics; N-Methylaspartate; Neurons; Onium Compounds; Organophosphorus Compounds; Potassium; Pregnancy; Prosencephalon; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Tritium | 1995 |
Rapid acquisition of dendritic spines by visual thalamic neurons after blockade of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Dendrites; Female; Ferrets; Geniculate Bodies; In Vitro Techniques; Microscopy, Confocal; N-Methylaspartate; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate; Reference Values | 1995 |
Prenatal exposure of rats to ammonia impairs NMDA receptor function and affords delayed protection against ammonia toxicity and glutamate neurotoxicity.
Topics: Aging; Ammonia; Animals; Aspartate Aminotransferases; Cells, Cultured; Cerebellum; Diet; Dizocilpine Maleate; Female; Glutamic Acid; L-Lactate Dehydrogenase; Lactation; N-Methylaspartate; Neurons; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 1995 |
Development of dopamine and N-methyl-D-aspartate systems in rat brain: the effect of prenatal phencyclidine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Female; Frontal Lobe; Glutamates; Glutamic Acid; Hydroxyindoleacetic Acid; Male; Methamphetamine; N-Methylaspartate; Phencyclidine; Pipecolic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1993 |
Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Animals; Carcinoma, Embryonal; Cell Differentiation; Dizocilpine Maleate; Electrophysiology; Female; Immunohistochemistry; Indicators and Reagents; Ion Channels; Kainic Acid; Mice; N-Methylaspartate; Neuroglia; Neurons; Pregnancy; Quinoxalines; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tretinoin; Tumor Cells, Cultured | 1993 |
Modulation of the glutamate-evoked release of arachidonic acid from mouse cortical neurons: involvement of a pH-sensitive membrane phospholipase A2.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amiloride; Ammonium Chloride; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Female; Glutamic Acid; Harmaline; Hydrogen-Ion Concentration; Immunohistochemistry; Kainic Acid; Kinetics; Kynurenic Acid; Mice; N-Methylaspartate; Neurons; Phospholipases A; Phospholipases A2; Pregnancy; Time Factors; Tritium | 1995 |
Expression of the neural axon adhesion molecule L1 in the developing and adult rat brain.
Topics: 4-Aminopyridine; Animals; Brain; Cell Adhesion Molecules, Neuronal; Cerebellum; Female; Gene Expression Regulation, Developmental; Glycosylation; Leukocyte L1 Antigen Complex; N-Methylaspartate; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1994 |
Protective effects of a vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in cultured cortical neurons.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Neurotransmitter Agents; Nitroprusside; Pregnancy; Rats; S-Adenosylmethionine; Vitamin B 12 | 1993 |
N-methyl-D-aspartic acid/glycine interactions on the control of 5-hydroxytryptamine release in raphe primary cultures.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Gestational Age; Glutamates; Glutamic Acid; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Pregnancy; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Rhombencephalon; Serotonin; Strychnine; Valine | 1993 |
The dihydropyridine nitrendipine reduces N-methyl-D-aspartate (NMDA)-evoked currents of rodent cortical neurons through a direct interaction with the NMDA receptor-associated ion channel.
Topics: Animals; Calcium Channels; Cells, Cultured; Cerebral Cortex; Female; Mice; N-Methylaspartate; Nitrendipine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Effects of prenatal ethanol exposure on N-methyl-D-aspartate-mediated calcium entry into dissociated neurons.
Topics: Animals; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ethanol; Female; Fetus; Glycine; Magnesium; Male; N-Methylaspartate; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
Non-classical glutamate receptors, blocked by both NMDA and non-NMDA antagonists, stimulate nitric oxide production in neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Cells, Cultured; Corpus Striatum; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Mice; N-Methylaspartate; Neurons; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pregnancy; Quinoxalines; Quisqualic Acid; Receptors, Glutamate | 1993 |
A developmental decrease in NMDA-mediated spontaneous firing in cultured rat cerebral cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Culture Media; Electrophysiology; Female; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin | 1993 |
Whole cell and single channel analysis of the kinetics of glycine-sensitive N-methyl-D-aspartate receptor desensitization.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Cells, Cultured; Female; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Neurons; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi; Synapses | 1993 |
Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats.
Topics: alpha-Methyltyrosine; Animals; Animals, Newborn; Behavior, Animal; Brain; Dizocilpine Maleate; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Female; Gene Expression; Genes, fos; Levodopa; Male; Methyltyrosines; N-Methylaspartate; Pipecolic Acids; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Serotonin; Tyrosine 3-Monooxygenase | 1993 |
Effect of KB-2796, a new diphenylpiperazine Ca2+ antagonist, on glutamate-induced neurotoxicity in rat hippocampal primary cell cultures.
Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Chelating Agents; Female; Glutamates; Glutamic Acid; Hippocampus; N-Methylaspartate; Nervous System Diseases; Piperazines; Pregnancy; Rats; Rats, Wistar | 1993 |
Calcium indicators and excitotoxicity in cultured cortical neurons.
Topics: Aniline Compounds; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Female; Fluorescent Dyes; Fura-2; Histocytochemistry; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Xanthenes | 1993 |
Effects of selected neuroactive chemicals on calcium transporting systems in rat cerebellum and on survival of cerebellar granule cells.
Topics: Aluminum; Animals; Biological Transport; Calcium; Calcium Radioisotopes; Cerebellum; Chlorpromazine; Cytoplasmic Granules; Female; Male; Microsomes; Mitochondria; N-Methylaspartate; Pregnancy; Rats; Synaptosomes | 1993 |
Blockade of retinal NMDA receptors by sodium nitroprusside is probably due to nitric oxide formation.
Topics: Animals; Female; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Nitric Oxide; Nitroprusside; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Retina | 1993 |
Effects of in vitro ethanol and fetal ethanol exposure on glutathione stimulation of N-methyl-D-aspartate receptor function.
Topics: Animals; Animals, Newborn; Brain; Calcium; Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glutathione; Glutathione Disulfide; Male; N-Methylaspartate; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Sleep Stages | 1993 |
Excitatory amino acid regulation of the enkephalin phenotype in mouse embryonic spinal cord cultures.
Topics: Amino Acids; Animals; Blotting, Northern; Cells, Cultured; Down-Regulation; Electric Stimulation; Enkephalins; Female; Ganglia, Spinal; Ligands; Mice; Mice, Inbred C57BL; N-Methylaspartate; Phenotype; Pregnancy; Protein Precursors; Receptors, Glutamate; RNA, Messenger; Spinal Cord; Tetrodotoxin | 1993 |
Selective reduction of N-methyl-D-aspartate-evoked responses by 1,3-di(2-tolyl)guanidine in mouse and rat cultured hippocampal pyramidal neurones.
Topics: Amino Acids; Animals; Anticonvulsants; Binding, Competitive; Calcium; Cells, Cultured; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Fura-2; Guanidines; Hippocampus; Mice; N-Methylaspartate; Neurons; Pregnancy; Pyramidal Tracts; Rats; Rats, Wistar; Receptors, sigma; Spectrometry, Fluorescence | 1993 |
Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats.
Topics: Animals; Animals, Newborn; Body Temperature; Brain; Brain Ischemia; Female; Fibroblast Growth Factor 2; Hypoxia; N-Methylaspartate; Pregnancy; Rats | 1993 |
Delayed administration of basic fibroblast growth factor protects against N-methyl-D-aspartate neurotoxicity in neonatal rats.
Topics: Animals; Animals, Newborn; Corpus Striatum; Female; Fibroblast Growth Factor 2; Injections; Injections, Intraperitoneal; N-Methylaspartate; Nervous System Diseases; Pregnancy; Rats; Rats, Sprague-Dawley | 1993 |
Interaction of ascorbic acid with the neurotoxic effects of NMDA and sodium nitroprusside.
Topics: Animals; Ascorbic Acid; Brain; Calcium; Cell Death; Cell Survival; Cells, Cultured; Drug Interactions; Excitatory Amino Acid Agonists; Female; N-Methylaspartate; Neurons; Nitric Oxide; Nitroprusside; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Vasodilator Agents | 1996 |
A lesion and neuroanatomical tract-tracing analysis of the role of the bed nucleus of the stria terminalis in retrieval behavior and other aspects of maternal responsiveness in rats.
Topics: Animals; Brain Mapping; Female; Maternal Behavior; N-Methylaspartate; Nerve Net; Neural Pathways; Neurons; Pregnancy; Preoptic Area; Rats; Substantia Innominata | 1996 |
A new compound (AZ36041) promotes the survival of the neurons and reduces neurotoxicity of Alzheimer's beta-amyloid protein.
Topics: Amyloid beta-Peptides; Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Dizocilpine Maleate; Female; Hippocampus; N-Methylaspartate; Neurons; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar; Sulfonamides; Thiazoles | 1995 |
Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Bicuculline; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Glycine Agents; Motor Neurons; N-Methylaspartate; Patch-Clamp Techniques; Postpartum Period; Pregnancy; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Strychnine; Tetrodotoxin | 1996 |
Opioid effects on 45Ca2+ uptake and glutamate release in rat cerebral cortex in primary culture.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Biological Transport; Calcium Radioisotopes; Cells, Cultured; Cerebral Cortex; Dynorphins; Excitatory Amino Acid Agonists; Female; Fetus; Glutamic Acid; Homeostasis; Membrane Potentials; Morphine; N-Methylaspartate; Naloxone; Narcotic Antagonists; Oligopeptides; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Opioid | 1997 |
Effects of prenatal ethanol exposure on brain region NMDA-mediated increase in intracellular calcium and the NMDAR1 subunit in forebrain.
Topics: Animals; Brain Mapping; Calcium; Calcium Channels; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Male; N-Methylaspartate; Nerve Tissue Proteins; Pregnancy; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate | 1997 |
The role of endogenous nitric oxide synthesis in contractility of term or preterm human myometrium.
Topics: Arginine; Female; Humans; Muscle Contraction; Myometrium; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Obstetric Labor, Premature; Pregnancy | 1997 |
Evidence that the early loss of membrane protein kinase C is a necessary step in the excitatory amino acid-induced death of primary cortical neurons.
Topics: Alkaloids; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzophenanthridines; Calcium; Carcinogens; Cell Death; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Fetus; Gene Expression; Glutamic Acid; Kainic Acid; Membrane Proteins; N-Methylaspartate; Naphthalenes; Neurons; Phenanthridines; Potassium Chloride; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture.
Topics: Amyloid beta-Peptides; Animals; Calcium; Calpain; Caspase 1; Cell Death; Cells, Cultured; Cysteine Endopeptidases; DNA Fragmentation; Endopeptidases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Interleukin-1; N-Methylaspartate; Neurotoxins; Peptide Fragments; Pregnancy; Pyramidal Cells; Rats; Staurosporine | 1997 |
Responses to N-methyl-D-aspartate and kainic acid in cerebellar granule cells of lead-exposed rat pups.
Topics: Administration, Oral; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Female; Kainic Acid; Lead; Maternal Exposure; Maternal-Fetal Exchange; N-Methylaspartate; Pregnancy; Rats | 1998 |
Prenatal ethanol exposure enhances glutamate release stimulated by quisqualate in rat cerebellar granule cell cultures.
Topics: Alcoholism; Amino Acids; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Ethanol; Female; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Potassium Chloride; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
The fatty acid composition of maternal diet affects the response to excitotoxic neural injury in neonatal rat pups.
Topics: Animals; Animals, Newborn; Atrophy; Brain; Corn Oil; Dietary Fats; Excitatory Amino Acid Agonists; Fatty Acids; Female; Fish Oils; Lactation; Milk; N-Methylaspartate; Neurons; Neurotoxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1998 |
BDNF gene transcripts in mesencephalic neurons and its differential regulation by NMDA.
Topics: Animals; Blotting, Southern; Brain-Derived Neurotrophic Factor; Dopamine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Mesencephalon; N-Methylaspartate; Neurons; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; RNA, Messenger; Transcription, Genetic | 1998 |
Genesis of spontaneous rhythmic motor patterns in the lumbosacral spinal cord of neonate mouse.
Topics: Animals; Animals, Newborn; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Locomotion; Magnesium; Membrane Potentials; Mice; Motor Neurons; N-Methylaspartate; Periodicity; Pregnancy; Quinoxalines; Spinal Cord | 1998 |
Synaptic plasticity in the CA1 and CA3 hippocampal region of pre- and postnatally lead-exposed rats.
Topics: Animals; Animals, Newborn; Brain; Electric Stimulation; Female; Hippocampus; Lead; Lead Poisoning; Long-Term Potentiation; Mossy Fibers, Hippocampal; N-Methylaspartate; Neuronal Plasticity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Synapses | 1998 |
Neurotoxic effects of feline immunodeficiency virus, FIV-PPR.
Topics: Acquired Immunodeficiency Syndrome; Animals; Baculoviridae; Brain Chemistry; Calcium; Calcium Signaling; Cats; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Encephalitis; Excitatory Amino Acid Agonists; Feline Acquired Immunodeficiency Syndrome; Female; Gene Products, env; Glutamic Acid; Immunodeficiency Virus, Feline; L-Lactate Dehydrogenase; N-Methylaspartate; Neurons; Pregnancy; Receptors, N-Methyl-D-Aspartate | 1998 |
The teratogenicity of N-methyl-D-aspartate (NMDA) receptor antagonists.
Topics: Animals; Antitussive Agents; Chick Embryo; Dextromethorphan; Female; Humans; N-Methylaspartate; Pregnancy; Rabbits; Receptors, N-Methyl-D-Aspartate; Teratogens | 1998 |
The teratogenicity of N-methyl-D-aspartate (NMDA) receptor antagonists.
Topics: Animals; Antitussive Agents; Chick Embryo; Dextromethorphan; Female; Humans; Maternal-Fetal Exchange; N-Methylaspartate; Pregnancy; Receptors, N-Methyl-D-Aspartate; Teratogens | 1998 |
Ethanol modulation of nicotinic acetylcholine receptor currents in cultured cortical neurons.
Topics: Acetylcholine; Animals; Bungarotoxins; Cells, Cultured; Ethanol; Female; Frontal Lobe; gamma-Aminobutyric Acid; N-Methylaspartate; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 1999 |
Evidence that brain-derived neurotrophic factor neuroprotection is linked to its ability to reverse the NMDA-induced inactivation of protein kinase C in cortical neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium; Cerebral Cortex; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Membrane Potentials; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Phosphorylation; Pregnancy; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine | 1999 |
Excitotoxic death of a subset of embryonic rat motor neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Culture Techniques; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glutamine; Glycine; Kainic Acid; Membrane Potentials; Motor Neurons; N-Methylaspartate; Nerve Tissue Proteins; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Complex influence of the L-type calcium-channel agonist BayK8644(+/-) on N-methyl-D-aspartate responses and neuronal survival.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Survival; Charybdotoxin; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Agonists; Female; Fluorescent Dyes; Fura-2; Hippocampus; Ion Channel Gating; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Acute N-methyl-D,L-aspartate administration stimulates the luteinizing hormone releasing hormone pulse generator in the ovine fetus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Feedback; Female; Fetal Blood; Fetus; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infusions, Intravenous; Luteinizing Hormone; N-Methylaspartate; Pituitary Gland; Pregnancy; Prolactin; Sheep; Triptorelin Pamoate | 1999 |
N-methyl-D-aspartate (NMDA)-mediated corticotropin-releasing factor (CRF) release in cultured rat amygdala neurons.
Topics: Amygdala; Animals; Cells, Cultured; Corticotropin-Releasing Hormone; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Magnesium; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Na+-K+-2Cl- cotransporter in immature cortical neurons: A role in intracellular Cl- regulation.
Topics: Animals; Biological Transport; Blotting, Western; Carrier Proteins; Cerebral Cortex; Chelating Agents; Chlorides; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Immunohistochemistry; N-Methylaspartate; Neurons; Piperidines; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Sodium-Potassium-Chloride Symporters; Staining and Labeling | 1999 |
NMDA receptor-mediated calcium influx in cerebral cortical synaptosomes of the hypoxic guinea pig fetus.
Topics: Animals; Calcium; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Fetal Hypoxia; Glutamic Acid; Glycine; Guinea Pigs; N-Methylaspartate; Potassium Chloride; Pregnancy; Receptors, N-Methyl-D-Aspartate; Synaptosomes; Thapsigargin | 1999 |
Perinatal changes in hypothalamic N-methyl-D-aspartate receptors and their relationship to gonadotropin-releasing hormone neurons.
Topics: Animals; Animals, Newborn; Female; Gene Expression; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Hypothalamus, Anterior; Male; N-Methylaspartate; Neurons; Pregnancy; Preoptic Area; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger | 1999 |
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepines; Calcium; Cells, Cultured; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Fetus; GluK2 Kainate Receptor; GluK3 Kainate Receptor; Kainic Acid; Membrane Potentials; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Potassium Chloride; Pregnancy; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1999 |
N-methyl-D-aspartate receptor binding is altered and seizure potential reduced in pregnant rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Convulsants; Dizocilpine Maleate; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hippocampus; Male; N-Methylaspartate; Pregnancy; Pregnancy, Animal; Radioligand Assay; Rats; Rats, Long-Evans; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
Ethanol pretreatment enhances NMDA excitotoxicity in biogenic amine neurons: protection by brain derived neurotrophic factor.
Topics: Animals; Biogenic Amines; Brain-Derived Neurotrophic Factor; Cells, Cultured; Central Nervous System Depressants; Ethanol; Excitatory Amino Acid Agonists; Female; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley | 1999 |
Prenatal morphine exposure alters N-methyl-D-aspartate- and kainate-induced seizures in adult male rats.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Fetus; Kainic Acid; Male; Morphine; N-Methylaspartate; Narcotics; Pregnancy; Rats; Seizures | 2000 |
Chronic NMDA exposure accelerates development of GABAergic inhibition in the superior colliculus.
Topics: Aging; Animals; Carrier Proteins; Coloring Agents; Electrophysiology; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunohistochemistry; Lysine; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; N-Methylaspartate; Neurons; Organic Anion Transporters; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Superior Colliculi | 2000 |
Progesterone attenuates persistent inflammatory hyperalgesia in female rats: involvement of spinal NMDA receptor mechanisms.
Topics: Animals; Estrus; Excitatory Amino Acid Agonists; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Lactation; N-Methylaspartate; Ovariectomy; Pregnancy; Progesterone; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2000 |
Activity-dependent neuronal control of gap-junctional communication in astrocytes.
Topics: Action Potentials; Animals; Astrocytes; Calcium Signaling; Cell Communication; Cell Count; Cell Membrane Permeability; Cells, Cultured; Connexin 43; Embryo, Mammalian; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Neurotoxins; Pregnancy; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, GABA-A; Synaptic Transmission; Tetrodotoxin; Time Factors; Up-Regulation | 2000 |
Functional ionotropic glutamate receptors emerge during terminal cell division and early neuronal differentiation of rat neuroepithelial cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Bromodeoxyuridine; Calcium; Cell Differentiation; Cells, Cultured; DNA Primers; Epithelial Cells; Epitopes; Excitatory Amino Acid Agonists; Female; Flow Cytometry; Gene Expression Regulation, Developmental; Kainic Acid; Membrane Potentials; Mitosis; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Polymerase Chain Reaction; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Stem Cells; Telencephalon; Transcription, Genetic | 2000 |
Fetal alcohol exposure alters neurosteroid modulation of hippocampal N-methyl-D-aspartate receptors.
Topics: Animals; Cells, Cultured; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glycine; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pregnancy; Pregnenolone; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2000 |
N-Acetylated alpha-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin.
Topics: Animals; Brain; Carboxypeptidases; Cells, Cultured; Dipeptides; Female; Glutamate Carboxypeptidase II; N-Methylaspartate; Neuroprotective Agents; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Whole brain spheroid cultures as a model to study the development of nitric oxide synthase-guanylate cyclase signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Atrial Natriuretic Factor; Brain; Cell Culture Techniques; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Guanylate Cyclase; N-Methylaspartate; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Oxadiazoles; Phosphodiesterase Inhibitors; Pregnancy; Quinoxalines; Rats; Rats, Inbred Lew; Signal Transduction; Vasodilator Agents | 2000 |
Estrogen differentially alters NMDA- and kainate-induced seizures in prenatally morphine- and saline-exposed adult female rats.
Topics: Analgesics, Opioid; Animals; Estradiol; Excitatory Amino Acid Agonists; Female; Kainic Acid; Morphine; N-Methylaspartate; Ovariectomy; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Seizures; Sodium Chloride; Stereotyped Behavior | 2000 |
The effects of propofol on NMDA- or nitric oxide-mediated neurotoxicity in vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Female; Fetus; Free Radical Scavengers; In Vitro Techniques; N-Methylaspartate; Neurons; Nitric Oxide; Nitric Oxide Donors; Pregnancy; Propofol; Rats; Rats, Wistar; Triazenes | 2001 |
Altered responsiveness to stress and NMDA following prenatal exposure to cocaine.
Topics: Aging; Animals; Behavior, Animal; Cocaine; Cold Temperature; Corticosterone; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Female; Immobilization; Male; N-Methylaspartate; Pain Measurement; Physical Endurance; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Psychological; Swimming | 2001 |
NMDA recepter-mediated neuroprotection by essential oils from the rhizomes of Acorus gramineus.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Indoles; Male; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Oils, Volatile; Plant Oils; Plants, Medicinal; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 2001 |
Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: effects on long-term potentiation and [3H]MK-801 binding in occipital cortex and hippocampus.
Topics: Administration, Oral; Analysis of Variance; Animals; Animals, Newborn; Binding Sites; Brain; Chlorodiphenyl (54% Chlorine); Diet; Dizocilpine Maleate; Electrophysiology; Female; Hippocampus; In Vitro Techniques; Ion Channels; Long-Term Potentiation; Male; Maternal Exposure; Maternal-Fetal Exchange; Muscimol; N-Methylaspartate; Neuronal Plasticity; Polychlorinated Biphenyls; Pregnancy; Rats; Rats, Long-Evans; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Time Factors; Tritium; Visual Cortex | 2001 |
Delayed postnatal development of NMDA receptor function in medium-sized neurons of the rat striatum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Organ Culture Techniques; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Co-administration of dextromethorphan during pregnancy and throughout lactation significantly decreases the adverse effects associated with chronic morphine administration in rat offspring.
Topics: Analgesics, Opioid; Animals; Antitussive Agents; Body Weight; Dextromethorphan; Drug Combinations; Drug Tolerance; Female; Hippocampus; Injections, Subcutaneous; Lactation; Longevity; Male; Morphine; Morphine Dependence; N-Methylaspartate; Pain Measurement; Pain Threshold; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 2001 |
Changes in the glutamate release and uptake of cerebellar cells in perinatally nicotine-exposed rat pups.
Topics: Animals; Animals, Newborn; Cerebellum; Dizocilpine Maleate; Female; Glutamic Acid; Male; N-Methylaspartate; Neurons; Nicotine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2001 |
Age-related differences in NMDA responses in cultured rat hippocampal neurons.
Topics: Aging; Animals; Calcium; Cell Differentiation; Cell Membrane; Cells, Cultured; Female; Fetus; Hippocampus; Intracellular Fluid; Ion Channels; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pregnancy; Rats; Rats, Inbred F344; Reaction Time; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2001 |
Cross-tolerance to otherwise lethal N-methyl-D-aspartate and oxygen-glucose deprivation in preconditioned cortical cultures.
Topics: Aniline Compounds; Animals; Biomarkers; Brain Ischemia; Calcium; Calpain; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Female; Fluorescent Antibody Technique; Fluorescent Dyes; Glucose; Ischemic Preconditioning; Microtubule-Associated Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Oxygen; Pregnancy; Rats; Xanthenes | 2001 |
Effects of alpha(2)-adrenoceptor agonists on perinatal excitotoxic brain injury: comparison of clonidine and dexmedetomidine.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-2 Receptor Agonists; Animals; Animals, Newborn; Brain; Clonidine; Dexmedetomidine; Excitatory Amino Acid Agonists; Female; Ibotenic Acid; Mice; N-Methylaspartate; Neuroprotective Agents; Pregnancy | 2002 |
NMDA-induced calcium loads recycle across the mitochondrial inner membrane of hippocampal neurons in culture.
Topics: Animals; Calcium; Calcium Channels; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Clonazepam; Coloring Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Female; Hippocampus; Mitochondria; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sodium; Sodium-Calcium Exchanger; Thiazepines; Uncoupling Agents | 2002 |
A functional neuroanatomical investigation of the role of the medial preoptic area in neural circuits regulating maternal behavior.
Topics: Animals; Brain Mapping; Dopamine; Excitatory Amino Acid Agonists; Female; Functional Laterality; Gene Expression Regulation; Genes, fos; Immunohistochemistry; Male; Maternal Behavior; Motivation; N-Methylaspartate; Nerve Net; Neurons; Postpartum Period; Pregnancy; Preoptic Area; Proto-Oncogene Proteins c-fos; Rats | 2002 |
Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity.
Topics: Animals; Cells, Cultured; Citrates; Citric Acid Cycle; Corpus Striatum; Electron Transport Complex II; Female; Malonates; Metabolism, Inborn Errors; Methylmalonic Acid; Multienzyme Complexes; N-Methylaspartate; Neurons; Oxidoreductases; Pregnancy; Rats; Rats, Wistar; Succinate Dehydrogenase | 2002 |
Site and mechanism of action of dynorphin A-(1-13) and N-methyl-D-aspartate on ACTH release in fetal sheep.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenocorticotropic Hormone; Animals; Cyclooxygenase Inhibitors; Dynorphins; Female; Fetus; Hypothalamus; Indomethacin; N-Methylaspartate; Peptide Fragments; Pituitary Gland; Placenta; Pregnancy; Receptors, Opioid, kappa; Sheep | 2002 |
Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus.
Topics: Acorus; Allylbenzene Derivatives; Animals; Anisoles; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Medicine, East Asian Traditional; N-Methylaspartate; Neurons; Neuroprotective Agents; Plant Extracts; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2002 |
Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Animals; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Cyclic Nucleotide Phosphodiesterases, Type 4; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Guanylate Cyclase; Hippocampus; N-Methylaspartate; Neurons; Nitric Oxide Donors; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rolipram | 2002 |
The polyamine diaminodecane (DA-10) produces a voltage-dependent flickery block of single NMDA receptor channels.
Topics: Animals; Diamines; Female; Ion Channels; Kinetics; N-Methylaspartate; Neurons; Oocytes; Polyamines; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Spermine | 1992 |
L-proline activates glutamate and glycine receptors in cultured rat dorsal horn neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium; Cells, Cultured; Female; Glutamates; Glycine; Kainic Acid; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Proline; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine | 1992 |
Inhibitory effect of CCK-8 and ceruletide on glutamate-induced rises in intracellular free calcium concentrations in rat neuron cultures.
Topics: Animals; Calcium; Cells, Cultured; Ceruletide; Cholecystokinin; Cytarabine; Female; Fura-2; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Wistar; Receptors, Cholecystokinin | 1992 |
Acetylcholine enhances NMDA-evoked calcium rise in hippocampal neurons.
Topics: Acetylcholine; Animals; Atropine; Caffeine; Calcium; Cells, Cultured; Female; Hippocampus; N-Methylaspartate; Neurons; Pregnancy; Rats | 1992 |
Sodium nitroprusside blocks NMDA receptors via formation of ferrocyanide ions.
Topics: Animals; Calcium; Female; Ferrocyanides; Mice; N-Methylaspartate; Neurons; Nitroprusside; Pipecolic Acids; Pregnancy; Receptors, N-Methyl-D-Aspartate | 1992 |
Ethanol inhibits excitotoxicity in cerebral cortical cultures.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Ethanol; Female; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Inbred Strains | 1992 |
Dextromethorphan and phencyclidine receptor ligands: differential effects on K(+)- and NMDA-evoked increases in cytosolic free Ca2+ concentration.
Topics: Animals; Calcium; Cyclopentanes; Cytosol; Dextromethorphan; Female; Fura-2; Hippocampus; Ketamine; Ligands; N-Methylaspartate; Parasympatholytics; Potassium; Pregnancy; Pyramidal Tracts; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1991 |
Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cerebral Cortex; Female; Glutamates; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Methionine Sulfoximine; Mice; N-Methylaspartate; Pregnancy | 1991 |
Prolonged exposure to N-methyl-D-aspartate increases intracellular and secreted somatostatin in rat cortical cells.
Topics: Animals; Cerebral Cortex; Female; Kainic Acid; N-Methylaspartate; Pregnancy; Quisqualic Acid; Rats; Somatostatin | 1991 |
Polyamines potentiate NMDA induced whole-cell currents in cultured striatal neurons.
Topics: Animals; Aspartic Acid; Cells, Cultured; Corpus Striatum; Female; Fetus; Ion Channels; N-Methylaspartate; Neurons; Polyamines; Pregnancy; Rats | 1990 |
Nystatin-perforated patch recordings disclose NMDA-induced outward currents in cultured neocortical neurons.
Topics: Administration, Topical; Animals; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Evoked Potentials; Female; Ion Channels; N-Methylaspartate; Neurons; Nystatin; Pregnancy; Rats | 1990 |
GABA release from mouse striatal neurons in primary culture as a test for the functional activity of N-methyl-D-aspartate (NMDA) antagonists.
Topics: Animals; Cells, Cultured; Corpus Striatum; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Ion Channels; Kynurenic Acid; Ligands; Mice; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1991 |
Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Carbamazepine; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; Female; Ion Channels; Membrane Potentials; Mice; N-Methylaspartate; Neurons; Phenytoin; Pregnancy; Spinal Cord | 1990 |
Spontaneous and NMDA evoked motor rhythms in the neonatal mouse spinal cord: an in vitro study with comparisons to in situ activity.
Topics: Animals; Animals, Newborn; Electromyography; Female; Hindlimb; In Vitro Techniques; Locomotion; Magnesium; Mice; Muscles; N-Methylaspartate; Pregnancy; Spinal Cord; Transplantation, Homologous | 1991 |
Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Embryo, Mammalian; Female; N-Methylaspartate; Neurons; Phencyclidine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Parallel development of excitotoxic vulnerability to N-methyl-D-aspartate and kainate in dispersed cultures of the rat cerebral cortex.
Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Female; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Cytotoxic effect of glutamate and its agonists on mouse hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Cells, Cultured; Dipeptides; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Glutamates; Glutamic Acid; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurons; Pregnancy; Quinolinic Acid; Quinolinic Acids | 1990 |
NMDA antagonists prevent hypothermic injury and death of mammalian spinal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Survival; Dizocilpine Maleate; Female; Freezing; Hypothermia, Induced; Ketamine; Mice; N-Methylaspartate; Neurons; Pregnancy; Spinal Cord Injuries | 1990 |
Protection by ethanol of cortical neurons from N-methyl-D-aspartate-induced neurotoxicity is associated with blocking calcium influx.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cerebral Cortex; Ethanol; Female; Ketamine; L-Lactate Dehydrogenase; N-Methylaspartate; Nervous System Diseases; Neurons; Pregnancy; Rats | 1990 |
Glutamate toxicity in immature cortical neurons precedes development of glutamate receptor currents.
Topics: Animals; Cerebral Cortex; Electrophysiology; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; N-Methylaspartate; Neurons; Pregnancy; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Cells, Cultured; Female; Hippocampus; Ibotenic Acid; N-Methylaspartate; Neurons; Pregnancy; Quinoxalines; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface | 1990 |
alpha-Cobratoxin blocks the nicotinic acetylcholine receptor in rat hippocampal neurons.
Topics: Acetylcholine; Animals; Bacterial Toxins; Cells, Cultured; Cobra Neurotoxin Proteins; Cyanobacteria Toxins; Female; Fetus; Glycine; Hippocampus; Marine Toxins; Membrane Potentials; Microcystins; N-Methylaspartate; Neurons; Nicotinic Antagonists; Pregnancy; Rats; Rats, Inbred Strains | 1990 |
Olfactory recognition: a simple memory system.
Topics: Amygdala; Animals; Female; Hypothalamus; Lidocaine; Male; Memory; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; N-Methylaspartate; Norepinephrine; Olfactory Bulb; Olfactory Pathways; Pheromones; Pregnancy; Pregnancy, Animal; Receptors, N-Methyl-D-Aspartate; Reproduction; Smell; Synapses | 1990 |
Role of the paraventricular nucleus in controlling the frequency of milk ejection and the facilitatory effect of centrally administered oxytocin in the suckled rat.
Topics: Animals; Aspartic Acid; Female; Injections, Intraventricular; Lactation; Milk Ejection; N-Methylaspartate; Oxytocin; Paraventricular Hypothalamic Nucleus; Pregnancy; Rats; Rats, Inbred Strains | 1990 |
GABA does not protect cerebro-cortical cultures against excitotoxic cell death.
Topics: Animals; Aspartic Acid; Cell Survival; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Glutamates; Kainic Acid; L-Lactate Dehydrogenase; N-Methylaspartate; Neurotoxins; Oxadiazoles; Pregnancy; Quisqualic Acid; Rats; Rats, Inbred Strains | 1990 |
The polyamine synthesis inhibitor alpha-difluoromethylornithine blocks NMDA-induced neurotoxicity.
Topics: Animals; Biogenic Polyamines; Cells, Cultured; Eflornithine; Female; Mice; Mice, Inbred C57BL; N-Methylaspartate; Nervous System Diseases; Neurons; Phencyclidine; Pregnancy; Rats | 1990 |
Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cycloleucine; Electrophysiology; Female; Hippocampus; Membrane Potentials; N-Methylaspartate; Neurons; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, Neurotransmitter; Strychnine | 1989 |
A potent antagonist of the strychnine insensitive glycine receptor has anticonvulsant properties.
Topics: Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Cortical Spreading Depression; Female; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pregnancy; Pyrrolidinones; Quinoxalines; Rats; Receptors, Glycine; Receptors, Neurotransmitter; Seizures; Strychnine | 1989 |
Qualitative changes in luteinizing hormone and prolactin responses to N-methyl-aspartic acid during lactation in the rat.
Topics: Animals; Aspartic Acid; Female; Hypothalamus; Lactation; Luteinizing Hormone; Male; N-Methylaspartate; Pituitary Hormone-Releasing Hormones; Pregnancy; Prolactin; Rats; Rats, Inbred Strains; Sex Factors | 1989 |
Synaptic transmission between dorsal root ganglion and dorsal horn neurons in culture: antagonism of monosynaptic excitatory postsynaptic potentials and glutamate excitation by kynurenate.
Topics: Animals; Aspartic Acid; Cells, Cultured; Evoked Potentials; Female; Ganglia, Spinal; Glutamates; Glutamic Acid; Kynurenic Acid; N-Methylaspartate; Pregnancy; Rats; Spinal Cord; Synaptic Transmission | 1985 |
High concentrations of naloxone attenuate N-methyl-D-aspartate receptor-mediated neurotoxicity.
Topics: Animals; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Female; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Naloxone; Nervous System Diseases; Oxadiazoles; Pregnancy; Quisqualic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1987 |
Neurotoxic lesions of the anterior hypothalamus disrupt the photoperiodic but not the circadian system of the Syrian hamster.
Topics: Animals; Aspartic Acid; Circadian Rhythm; Cricetinae; Estrus; Female; Hypothalamus, Anterior; Light; Male; Mesocricetus; Motor Activity; N-Methylaspartate; Periodicity; Pregnancy; Seasons; Sexual Behavior, Animal | 1985 |