n-methylaspartate has been researched along with Neurodegenerative Diseases in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 21 (50.00) | 29.6817 |
| 2010's | 12 (28.57) | 24.3611 |
| 2020's | 7 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kusiak, A; Ossowska, A; Świetlik, D | 1 |
| Acebes, Á; Acevedo-Arozena, A; Brito-Armas, JM; Cuesto, G; Estévez-Silva, HM; Marcellino, DJ; Romero, N | 1 |
| Adams, N; Cope, TE; Hughes, LE; Jones, PS; Kocagoncu, E; Murley, AG; Naessens, M; Perry, A; Rouse, MA; Rowe, JB; Street, D | 1 |
| Dash, SS; Kandy, SK; Markandeya, YS; Mehta, B; Nimonkar, MM | 1 |
| Cruz-Martins, N; Ezzat, SM; Kumar, D; Li, L; Painuli, S; Semwal, P; Sharifi-Rad, J; Taheri, Y; Zam, W; Zuo, P | 1 |
| Bedeschi, M; Collina, S; Denora, N; Dondio, G; Franchini, S; Linciano, P; Marino, N; Marsala, A; Miserocchi, G; Peviani, M; Rossi, D; Rossino, G; Sorbi, C; Tesei, A | 1 |
| Alilov, A; Dzhanbekova, K; Fokin, M; Gadzhiev, M; Gulyaeva, K; Idiatullin, R; Kachanov, D; Karabanova, A; Magomedov, S; Zablotskaya, P | 1 |
| Hayashi, H; Inoue, D; Iwatani, Y; Ohata, M; Sato, S; Suzuki, K; Takagi, N; Yamada, M; Yuan, B | 1 |
| Alobid, I; Berenguer, J; Bernabeu, M; Langdon, C; Laxe, S; Lehrer, E; Marin, C; Mariño-Sánchez, F; Mullol, J | 1 |
| Carvajal, FJ; Cerpa, W; Minniti, AN; Mira, RG; Rovegno, M | 1 |
| Lin, SE; Shen, LJ; Wei, MF; Wu, FL | 1 |
| Fritschy, JM; Jirak, D; Kleteckova, L; Kubesova, A; Rambousek, L; Vales, K | 1 |
| Andrade, C; Batlle, M; Gimeno-Bayón, J; Mahy, N; Martínez-Moreno, M; Ortega, FJ; Rodríguez, MJ | 1 |
| Atalay, M; Chung, HY; Jakus, J; Jung, KJ; Nyakas, C; Radák, Z; Sasvári, M; Stadler, K; Toldy, A | 1 |
| Dolga, AM; Eisel, UL; Granic, I; Luiten, PG; Nijholt, IM; Nyakas, C; van der Zee, EA | 1 |
| Abe, H; Boldyrev, AA; Bulygina, ER; Fedorova, TN; Meguro, K; Sato, T; Stvolinsky, SL; Tyulina, OV | 1 |
| Dierckx, RA; Elsinga, PH; Ishiwata, K; Luiten, PG; Nijholt, IM; Ramakrishnan, NK; Rybczynska, AA; van Waarde, A | 1 |
| Jahani-Asl, A; MacLaurin, JG; McBride, HM; Park, DS; Pilon-Larose, K; Slack, RS; Xu, W | 1 |
| Granic, I; Hulshof, HJ; Meerlo, P; Novati, A | 1 |
| Dawson, TM; Dawson, VL; Eacker, SM; Harraz, MM; Wang, X | 1 |
| Wisniewska, MB | 1 |
| Aruoma, OI; Gentleman, SM; Jen, LS; Moncaster, JA; Walsh, DT | 1 |
| Acarin, L; Castellano, B; González, B | 1 |
| Kerokoski, P; Pirttilä, T; Salminen, A; Soininen, H; Suuronen, T | 1 |
| Caccamo, D; Ientile, R; Macaione, S; Macaione, V; Torre, V | 1 |
| Bladin, C; Liberatore, GT; Medcalf, RL; Samson, A; Schleuning, WD | 1 |
| Camins, A; Camps, P; Canudas, AM; Jiménez, A; Muñoz-Torrero, D; Pallàs, M; Pubill, D; Sureda, FX; Verdaguer, E | 1 |
| Johansson, S; Luthman, J; Oberg, C; Radesäter, AC | 1 |
| Cheng, T; Fernández, JA; Gelbard, H; Griffin, JH; Guo, H; Insalaco, R; Liu, D; Zlokovic, BV | 1 |
| Beglopoulos, V; Chattarji, S; Choi, SY; Duff, K; Kandel, ER; Kelleher, RJ; Kirkwood, A; Malkani, S; Saura, CA; Shankaranarayana Rao, BS; Shen, J; Zhang, D | 1 |
| Domenici, MR; Frank, C; Grieco, R; Martire, A; Pepponi, R; Pintor, A; Popoli, P; Potenza, RL; Tebano, MT | 1 |
| Chen, J; Errico, SL; Freed, WJ | 1 |
| Gu, Z; Lipton, SA; Ma, Y; Masliah, E; Nakamura, T; Nomura, Y; Shi, ZQ; Uehara, T; Yao, D | 1 |
| Aschner, M; Cai, J; Gupta, RC; Jiang, GC; McLaughlin, BA; Milatovic, D; Nass, R; Tidwell, K | 1 |
| Eriksson, P; Fredriksson, A; Gordh, T; Pontén, E | 1 |
| Tsai, GE | 1 |
| Cui, H; Lau, AC; Tymianski, M | 1 |
| Conn, PJ; Levey, AI; Marino, MJ; Potter, LT; Rouse, ST | 1 |
| Doble, A | 1 |
| Bittigau, P; Hansen, HH; Hansen, HS; Hansen, SH; Ikonomidou, C | 1 |
| Mothet, JP | 1 |
| Azcoitia, I; Fernández-Ruiz, J; García-Segura, LM; Hansen, HH; Hansen, HS; Pons, S; Ramos, JA; Romero, J | 1 |
6 review(s) available for n-methylaspartate and Neurodegenerative Diseases
| Article | Year |
|---|---|
NMDA Inhibitors: A Potential Contrivance to Assist in Management of Alzheimer's Disease.
Topics: Alzheimer Disease; Humans; Memantine; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate | 2023 |
The cholinergic system, sigma-1 receptors and cognition.
Topics: Acetylcholine; Aging; Animals; Brain; Calcium; Cell Differentiation; Cholinergic Fibers; Cognition; Disease Models, Animal; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Psychotropic Drugs; Receptors, sigma; Sigma-1 Receptor | 2011 |
Physiological role of β-catenin/TCF signaling in neurons of the adult brain.
Topics: Adult; Animals; beta Catenin; Cell Differentiation; Cerebral Cortex; Glycogen Synthase Kinase 3; Hippocampus; Humans; Lymphoid Enhancer-Binding Factor 1; Mice; N-Methylaspartate; Neurodegenerative Diseases; Neurogenesis; Neuronal Plasticity; Neurons; Schizophrenia; Signal Transduction; TCF Transcription Factors; Thalamus; Wnt Proteins; Wnt Signaling Pathway | 2013 |
The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures.
Topics: Acute Disease; Animals; Benzimidazoles; Brain Ischemia; Cell Death; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Humans; Immunohistochemistry; Indicators and Reagents; Mice; Microscopy, Fluorescence; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Propidium; Receptors, N-Methyl-D-Aspartate | 2007 |
The role of excitotoxicity in neurodegenerative disease: implications for therapy.
Topics: AIDS Dementia Complex; Amyotrophic Lateral Sclerosis; Calcium; Excitatory Amino Acids; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Neurotransmitter Agents | 1999 |
Physiological relevance of endogenous free D-serine in the mammalian brain: are scientists on a royal road for the treatment of glutamatergic-related brain disorders?
Topics: Animals; Astrocytes; Brain Chemistry; Glutamic Acid; Humans; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate; Serine; Synaptic Transmission | 2001 |
36 other study(ies) available for n-methylaspartate and Neurodegenerative Diseases
| Article | Year |
|---|---|
Computational Modeling of Therapy with the NMDA Antagonist in Neurodegenerative Disease: Information Theory in the Mechanism of Action of Memantine.
Topics: Alzheimer Disease; Computer Simulation; Humans; Information Theory; Memantine; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate | 2022 |
Pridopidine Promotes Synaptogenesis and Reduces Spatial Memory Deficits in the Alzheimer's Disease APP/PS1 Mouse Model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Hydrogen Peroxide; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; N-Methylaspartate; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats | 2022 |
The neurophysiological effect of NMDA-R antagonism of frontotemporal lobar degeneration is conditional on individual GABA concentration.
Topics: Cross-Over Studies; Double-Blind Method; Frontotemporal Dementia; Frontotemporal Lobar Degeneration; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Memantine; N-Methylaspartate; Neurodegenerative Diseases | 2022 |
Astaxanthin Protection against Neuronal Excitotoxicity via Glutamate Receptor Inhibition and Improvement of Mitochondrial Function.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antioxidants; Calcium; Glutamic Acid; Humans; Mitochondria; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Reactive Oxygen Species; Receptors, AMPA; Receptors, Glutamate; Xanthophylls | 2022 |
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.
Topics: Animals; Humans; N-Methylaspartate; Neuroblastoma; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Piperidines; Receptors, sigma; Zebrafish | 2023 |
NEURODEGENERATION AND NMDA.
Topics: Brain; Humans; N-Methylaspartate; Neurodegenerative Diseases; Receptors, N-Methyl-D-Aspartate | 2023 |
Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Endocytosis; Furin; Humans; Low Density Lipoprotein Receptor-Related Protein-1; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Rats; Receptors, LDL; Signal Transduction; Stroke; trans-Golgi Network | 2019 |
Olfactory function in an excitotoxic model for secondary neuronal degeneration: Role of dopaminergic interneurons.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Dopaminergic Neurons; Interneurons; Lateral Ventricles; Magnetic Resonance Imaging; Male; N-Methylaspartate; Neurodegenerative Diseases; Neurogenesis; Neurotoxins; Olfaction Disorders; Olfactory Bulb; Rats; Rats, Sprague-Dawley | 2017 |
Age-related NMDA signaling alterations in SOD2 deficient mice.
Topics: Age Factors; Aging; Animals; Behavior, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; N-Methylaspartate; Neurodegenerative Diseases; Neuronal Plasticity; Neurons; Oxidative Stress; Phosphorylation; Protein Tyrosine Phosphatases, Non-Receptor; PTEN Phosphohydrolase; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Superoxide Dismutase; Synapses | 2018 |
Depletion of arginine by recombinant arginine deiminase induces nNOS-activated neurotoxicity in neuroblastoma cells.
Topics: Arginine; Cell Culture Techniques; Cell Survival; Humans; Hydrolases; Membrane Potential, Mitochondrial; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Recombinant Proteins | 2014 |
Rat intra-hippocampal NMDA infusion induces cell-specific damage and changes in expression of NMDA and GABAA receptor subunits.
Topics: Animals; Disease Models, Animal; Functional Laterality; Hippocampus; Male; Maze Learning; N-Methylaspartate; Nerve Degeneration; Neurodegenerative Diseases; Neuroimmunomodulation; Neurons; Rats, Long-Evans; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 2016 |
Diazoxide enhances excitotoxicity-induced neurogenesis and attenuates neurodegeneration in the rat non-neurogenic hippocampus.
Topics: Administration, Oral; Animals; Astrocytes; Diazoxide; Disease Models, Animal; Doublecortin Protein; Hippocampus; KATP Channels; Male; Microglia; N-Methylaspartate; Neurodegenerative Diseases; Neurogenesis; Neurons; Neuroprotective Agents; Rats, Wistar | 2016 |
The beneficial effects of nettle supplementation and exercise on brain lesion and memory in rat.
Topics: Animals; Antioxidants; Avoidance Learning; Behavior, Animal; Brain; Cerebellum; Free Radicals; Inflammation; Male; Memory; N-Methylaspartate; Neurodegenerative Diseases; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Wistar; Swimming; Urtica dioica | 2009 |
Pretreatment with lovastatin prevents N-methyl-D-aspartate-induced neurodegeneration in the magnocellular nucleus basalis and behavioral dysfunction.
Topics: Analysis of Variance; Animals; Avoidance Learning; Basal Nucleus of Meynert; Behavioral Symptoms; Choline O-Acetyltransferase; Chromones; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Maze Learning; Mice; Mice, Inbred C57BL; Morpholines; N-Methylaspartate; Neurodegenerative Diseases; Reaction Time | 2009 |
Biological activity of novel synthetic derivatives of carnosine.
Topics: Animals; Antioxidants; Biphenyl Compounds; Brain; Carnosine; Cells, Cultured; Cerebellar Cortex; Chromans; Dipeptidases; Erythrocytes; Hemolysis; Humans; Hydrogen Peroxide; Iron; Lipid Peroxidation; Molecular Structure; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Oxidants; Oxidative Stress; Picrates; Rats; Reactive Oxygen Species | 2010 |
The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.
Topics: Animals; Brain Injuries; Cell Death; Cell Survival; Cerebellum; Cytotoxins; Excitatory Amino Acid Agonists; GTP Phosphohydrolases; Mice; Mitochondrial Membranes; Mitochondrial Proteins; N-Methylaspartate; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons | 2011 |
Chronic partial sleep deprivation reduces brain sensitivity to glutamate N-methyl-D-aspartate receptor-mediated neurotoxicity.
Topics: Animals; Basal Nucleus of Meynert; Brain Chemistry; Cholinergic Neurons; Male; N-Methylaspartate; Neurodegenerative Diseases; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sleep Deprivation | 2012 |
MicroRNA-223 is neuroprotective by targeting glutamate receptors.
Topics: 3' Untranslated Regions; Animals; Calcium; Calcium Signaling; Excitatory Postsynaptic Potentials; HEK293 Cells; Hippocampus; Humans; Mice; MicroRNAs; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Stroke | 2012 |
Ergothioneine treatment protects neurons against N-methyl-D-aspartate excitotoxicity in an in vivo rat retinal model.
Topics: Amyloid beta-Protein Precursor; Animals; Antioxidants; Astrocytes; Cell Count; Cell Death; Disease Models, Animal; Down-Regulation; Ergothioneine; Female; Glial Fibrillary Acidic Protein; Glutamic Acid; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells | 2002 |
Decrease of proinflammatory molecules correlates with neuroprotective effect of the fluorinated salicylate triflusal after postnatal excitotoxic damage.
Topics: Administration, Oral; Animals; Astrocytes; Cyclooxygenase 2; Disease Models, Animal; Inflammation Mediators; Interleukin-1; Isoenzymes; Microglia; Microinjections; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Neutrophil Infiltration; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Long-Evans; Salicylates; Somatosensory Cortex; Tumor Necrosis Factor-alpha | 2002 |
Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation.
Topics: Animals; Calcimycin; Calpain; Cells, Cultured; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dipeptides; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Ionomycin; Ionophores; N-Methylaspartate; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Phosphorylation; Rats; tau Proteins | 2002 |
NMDA-evoked excitotoxicity increases tissue transglutaminase in cerebellar granule cells.
Topics: Animals; Animals, Newborn; Calcium Signaling; Cells, Cultured; Cerebellar Cortex; Excitatory Amino Acid Antagonists; Glutamic Acid; Membrane Potentials; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Transglutaminases; Up-Regulation | 2002 |
Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration.
Topics: Animals; Cell Count; Cell Survival; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Fibrinolytic Agents; Hippocampus; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Plasminogen Activators; Tissue Plasminogen Activator | 2003 |
Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage.
Topics: Aminoquinolines; Animals; Binding, Competitive; Calcium; Cell Death; Cells, Cultured; Cerebellum; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gliosis; Glutamic Acid; Heat-Shock Proteins; Heterocyclic Compounds, 4 or More Rings; HSP27 Heat-Shock Proteins; Isoquinolines; Mice; Molecular Chaperones; Motor Activity; N-Methylaspartate; Neoplasm Proteins; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats | 2003 |
The vitamin-E analog trolox and the NMDA antagonist MK-801 protect pyramidal neurons in hippocampal slice cultures from IL-1beta-induced neurodegeneration.
Topics: Animals; Animals, Newborn; Antioxidants; Chlormethiazole; Chromans; Dizocilpine Maleate; Excitatory Amino Acid Agonists; GABA Modulators; Hippocampus; Immunohistochemistry; Interleukin-1; N-Methylaspartate; Neurodegenerative Diseases; Neuroprotective Agents; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2003 |
Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3.
Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Caspases; Cells, Cultured; Cerebral Cortex; Fetus; Flavoproteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Protein C; Receptor, PAR-1; Receptors, Thrombin; Staurosporine; Tumor Suppressor Protein p53 | 2004 |
Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.
Topics: Activating Transcription Factor 1; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antibodies, Monoclonal; Association Learning; Behavior, Animal; Blotting, Western; Brain; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Carrier Proteins; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Disease Models, Animal; DNA-Binding Proteins; Excitatory Amino Acid Agonists; Fear; gag Gene Products, Human Immunodeficiency Virus; Gene Expression Regulation; Gene Products, gag; Immunohistochemistry; In Vitro Techniques; Lamin Type B; Long-Term Potentiation; Membrane Potentials; Membrane Proteins; Memory Disorders; Mice; Mice, Knockout; Microtubule-Associated Proteins; N-Methylaspartate; Neurodegenerative Diseases; Neuronal Plasticity; Patch-Clamp Techniques; Precipitin Tests; Presenilin-1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-fos; Reaction Time; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factors; Viral Proteins | 2004 |
Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum.
Topics: 4-Aminopyridine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Calcium; Corpus Striatum; Dose-Response Relationship, Drug; Glutamic Acid; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Models, Biological; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Phenethylamines; Pyrimidines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Synaptic Transmission; Triazines; Triazoles | 2004 |
Reactive oxygen species and p38 phosphorylation regulate the protective effect of Delta9-tetrahydrocannabinol in the apoptotic response to NMDA.
Topics: Animals; Apoptosis; Cell Line, Transformed; Cell Survival; Dose-Response Relationship, Drug; Dronabinol; Enzyme Activation; Enzyme Inhibitors; MAP Kinase Signaling System; N-Methylaspartate; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxins; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species | 2005 |
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration.
Topics: Alzheimer Disease; Animals; Binding Sites; Cell Line; Cysteine; Endoplasmic Reticulum; Humans; Molecular Chaperones; N-Methylaspartate; Neurodegenerative Diseases; Nitric Oxide; Parkinson Disease; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Disulfide-Isomerases; Protein Folding; Receptors, G-Protein-Coupled; Sulfhydryl Compounds; Ubiquitin | 2006 |
Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Cell Survival; Cells, Cultured; Cerebral Cortex; Energy Metabolism; Glutathione; Glutathione Disulfide; L-Lactate Dehydrogenase; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Organometallic Compounds; Rats; Rats, Sprague-Dawley | 2007 |
Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits.
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Animals, Newborn; Anti-Anxiety Agents; Apoptosis; Behavior, Animal; Brain; Diazepam; Disease Models, Animal; Drug Combinations; Drug Synergism; Excitatory Amino Acid Agonists; GABA Antagonists; Ketamine; Male; Maze Learning; Mice; N-Methylaspartate; Neurodegenerative Diseases; Propofol; Receptors, GABA-A; Sodium Chloride; Thiopental; Time Factors | 2007 |
Searching for rational anti N-methyl-D-aspartate treatment for depression.
Topics: Cognition Disorders; Depressive Disorder; Excitatory Amino Acid Antagonists; Humans; Ketamine; N-Methylaspartate; Neurodegenerative Diseases; Psychoses, Substance-Induced; Receptors, N-Methyl-D-Aspartate | 2007 |
Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells.
Topics: Animals; Carbachol; Elapid Venoms; Electrophysiology; Hippocampus; Male; Microscopy, Immunoelectron; Muscarinic Antagonists; N-Methylaspartate; Neurodegenerative Diseases; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal death.
Topics: Animals; Apoptosis; Arachidonic Acids; Brain Injuries; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Endocannabinoids; Ethanolamines; Male; N-Methylaspartate; Necrosis; Neurodegenerative Diseases; Neurons; Phospholipids; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Species Specificity; Wounds, Nonpenetrating | 2001 |
Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity.
Topics: Animals; Benzoxazines; Brain; Cannabinoids; Cell Survival; Cerebral Cortex; Corpus Striatum; Morpholines; N-Methylaspartate; Naphthalenes; Neurodegenerative Diseases; Neurotoxins; Parietal Lobe; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2002 |