Page last updated: 2024-08-22

n-methylaspartate and Neuralgia

n-methylaspartate has been researched along with Neuralgia in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (9.68)	18.2507
2000's	8 (25.81)	29.6817
2010's	15 (48.39)	24.3611
2020's	5 (16.13)	2.80

Authors

Authors	Studies
Guan, H; Tripathi, AS; Wu, D; Yan, T	1
Bonanno, G; Bonifacino, T; Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Micheli, L; Milanese, M; Scherz, MW; Torazza, C	1
Coimbra, NC; de Freitas, RL; De Gregorio, D; Dos Santos, WF; Gobbi, G; Medeiros, AC; Medeiros, P; Ruggiero, RN; Silva Júnior, PI	1
Condés-Lara, M; González-Hernández, A; Martínez-Lorenzana, G; Pérez-Ortega, J; Tello-García, IA	1
Chen, XM; Jiang, MH; Liang, SX; Liu, WT; Wang, ZF; Yu, XM; Zhang, LP; Zheng, MF	1
Avendaño, C; Fernández-Montoya, J; Negredo, P	1
Chang, JW; Jung, HH; Koh, CS; Kong, C; Lee, J; Shin, J; Yoon, MS	1
Felix, ER	1
Del Bel, EA; Dias, QM; Fais, RS; Genaro, K; Guethe, LM; Prado, WA; Rossaneis, AC	1
Jiang, W; Ma, X; Xu, T; Zhang, X; Zhao, D; Zhao, J; Zhong, W	1
Bang, S; Berta, T; Chen, G; Chen, W; Gao, YJ; Ji, RR; Lay, M; Park, CK; Xie, RG; Xu, ZZ; Zhao, LX	1
Beitz, AJ; Choi, HS; Choi, SR; Han, HJ; Kang, SY; Kwon, SG; Lee, JH; Moon, JY; Roh, DH; Yoon, SY	1
Kim, H; Lim, G; Ma, Y; Mao, J; Tian, Y; Wang, S	1
Halder, S; Khanna, N; Mehta, AK; Sharma, KK; Tandon, OP	1
Gadotti, VM; Zamponi, GW	1
Fitzgerald, M; Hathway, G; McKelvey, R; Vega-Avelaira, D	1
Alba-Delgado, C; Berrocoso, E; Mico, JA; Sánchez-Blázquez, P	1
Chaparro, LE; Gilron, I; Moore, RA; Wiffen, PJ	1
Battaglia, A; Cibert-Goton, V; Fredriksson, S; Gavazzi, I; Henkemeyer, M; Sears, T; Yuan, G	1
Gao, M; Jiang, E; Weng, HR; Yan, X	1
Brill, S; Di Vadi, PP; Hamann, W; Sedgwick, PM	1
Ackenheil, M; Offenbaecher, M	1
Chizh, BA; Christoph, T; Englberger, W; Reissmüller, E; Schiene, K	1
Apkarian, AV; Berra, HH; Centeno, MV; Lavarello, S; Millecamps, M; Rudick, CN; Tkatch, T	1
Jesse, CR; Nogueira, CW; Pinto, LG; Rocha, JB; Savegnago, L	1
Caramenti, G; Mario Biella, GE; Sotgiu, ML; Storchi, R; Valente, M	1
Dray, A; Krause, JE; McCarson, KE; Thompson, SWN; Urban, L	1
Jensen, TS; Sindrup, SH	1
Bonezzi, C; Demartini, L	1
Basbaum, AI; Malmberg, AB; Martin, WJ	1
Mao, J; Mayer, DJ	1

Reviews

7 review(s) available for n-methylaspartate and Neuralgia

Article	Year
The Glutamatergic System in Primary Somatosensory Neurons and Its Involvement in Sensory Input-Dependent Plasticity. International journal of molecular sciences, 2017, Dec-27, Volume: 19, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ganglia, Sensory; Glutamic Acid; Humans; Kainic Acid; N-Methylaspartate; Neuralgia; Neuronal Plasticity; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Sensory Receptor Cells; Synaptic Transmission	2017
Chronic neuropathic pain in SCI: evaluation and treatment. Physical medicine and rehabilitation clinics of North America, 2014, Volume: 25, Issue:3 Topics: Acupuncture Therapy; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents; Cannabinoids; Chronic Pain; Cognitive Behavioral Therapy; Combined Modality Therapy; Denervation; Humans; N-Methylaspartate; Neuralgia; Pain Management; Pain Measurement; Physical Therapy Modalities; Spinal Cord Injuries	2014
Combination pharmacotherapy for the treatment of neuropathic pain in adults. The Cochrane database of systematic reviews, 2012, Jul-11, Issue:7 Topics: Acetaminophen; Adult; Amines; Analgesics; Antidepressive Agents, Tricyclic; Benzodiazepinones; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Morphine; N-Methylaspartate; Neuralgia; Nortriptyline; Phenylurea Compounds; Pregabalin; Thioctic Acid; Tramadol	2012
Current trends in neuropathic pain treatments with special reference to fibromyalgia. CNS spectrums, 2005, Volume: 10, Issue:4 Topics: Analgesics; Analgesics, Opioid; Anticonvulsants; Fibromyalgia; Humans; Ketamine; N-Methylaspartate; Needs Assessment; Neuralgia	2005
Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain, 1999, Volume: 83, Issue:3 Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Carbamazepine; Diabetic Neuropathies; Humans; N-Methylaspartate; Narcotics; Neuralgia; Pain; Polyneuropathies; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors	1999
Treatment options in postherpetic neuralgia. Acta neurologica Scandinavica. Supplementum, 1999, Volume: 173 Topics: Analgesics; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Clonidine; Herpes Zoster; Humans; N-Methylaspartate; Neuralgia	1999
Spinal cord neuroplasticity following repeated opioid exposure and its relation to pathological pain. Annals of the New York Academy of Sciences, 2001, Volume: 933 Topics: Analgesics; Analgesics, Opioid; Animals; Benzamides; Dizocilpine Maleate; Drug Tolerance; Hot Temperature; Humans; Hyperalgesia; Morphine; Multiple Chemical Sensitivity; N-Methylaspartate; Narcotics; Nerve Degeneration; Nerve Tissue Proteins; Neuralgia; Neuronal Plasticity; Nitric Oxide; Phosphorylation; Poly(ADP-ribose) Polymerases; Posterior Horn Cells; Protein Kinase C; Protein Processing, Post-Translational; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, Opioid, mu; Sciatic Nerve; Spinal Cord	2001

Trials

1 trial(s) available for n-methylaspartate and Neuralgia

Article	Year
Efficacy of intravenous magnesium in neuropathic pain. British journal of anaesthesia, 2002, Volume: 89, Issue:5 Topics: Aged; Aged, 80 and over; Analgesics; Double-Blind Method; Female; Herpes Zoster; Humans; Infusions, Intravenous; Magnesium Sulfate; Male; Middle Aged; N-Methylaspartate; Neuralgia; Pain Measurement	2002

Other Studies

23 other study(ies) available for n-methylaspartate and Neuralgia

Article	Year
Epifriedelinol Ameliorates the Neuropathic Pain and Recovers the Function in Spinal Cord Injury by Downregulation of Neuronal Apoptosis and NMDA Receptor. The Tohoku journal of experimental medicine, 2022, Sep-29, Volume: 258, Issue:2 Topics: Animals; Apoptosis; Caspase 3; Down-Regulation; Glutamates; Hyperalgesia; Interleukin-6; N-Methylaspartate; Neuralgia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Tumor Necrosis Factors	2022
Pharmacological Profile of MP-101, a Novel Non-racemic Mixture of R- and S-dimiracetam with Increased Potency in Rat Models of Cognition, Depression and Neuropathic Pain. Cells, 2022, 12-13, Volume: 11, Issue:24 Topics: Animals; Cognition; D-Aspartic Acid; Depression; Glutamic Acid; N-Methylaspartate; Neuralgia; Rats	2022
Acanthoscurria gomesiana spider-derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid. Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:7 Topics: Animals; Antidepressive Agents; Comorbidity; Depression; Hyperalgesia; Male; N-Methylaspartate; Neuralgia; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spiders	2023
Oxytocin prevents neuronal network pain-related changes on spinal cord dorsal horn in vitro. Cell calcium, 2020, Volume: 90 Topics: Animals; Animals, Newborn; Calcium; Female; Formaldehyde; Male; N-Methylaspartate; Nerve Net; Neuralgia; Neurons; Oxytocin; Spinal Cord Dorsal Horn	2020
[Effect of wrist-ankle acupuncture on the expression of glutamate and NMDA receptor of the spinal dorsal horn in rats with neuropathic pain]. Zhen ci yan jiu = Acupuncture research, 2020, Aug-25, Volume: 45, Issue:8 Topics: Acupuncture Therapy; Animals; Glutamic Acid; Lower Extremity; N-Methylaspartate; Neuralgia; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Dorsal Horn; Upper Extremity	2020
Injecting NMDA and Ro 25-6981 in insular cortex induce neuroplastic changes and neuropathic pain-like behaviour. European journal of pain (London, England), 2018, Volume: 22, Issue:9 Topics: Animals; Central Nervous System Sensitization; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neural Cell Adhesion Molecule L1; Neuralgia; Neuronal Plasticity; Pain Threshold; Phenols; Piperidines; Rats; Rats, Sprague-Dawley; Sialic Acids	2018
Descending mechanisms activated by the anterior pretectal nucleus initiate but do not maintain neuropathic pain in rats. European journal of pain (London, England), 2015, Volume: 19, Issue:8 Topics: Anesthetics, Local; Animals; Constriction, Pathologic; Hyperalgesia; Lidocaine; Male; Methysergide; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neural Pathways; Neuralgia; Neurons; Pain Measurement; Physical Stimulation; Pretectal Region; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Sciatic Neuropathy	2015
Does modulation of spinal N-methyl-D-aspartic acid receptor by pre-activation accelerate the development of morphine tolerance? Medical hypotheses, 2015, Volume: 84, Issue:2 Topics: Animals; Drug Tolerance; Humans; Models, Neurological; Morphine; N-Methylaspartate; Neuralgia; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Nerve Roots	2015
β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain. Nature communications, 2016, 08-19, Volume: 7 Topics: Analgesics, Opioid; Animals; beta-Arrestin 2; Chronic Pain; Disease Models, Animal; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Humans; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Mice, Knockout; N-Methylaspartate; Neuralgia; Neurons; Peripheral Nerve Injuries; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Spinal Cord Dorsal Horn; Substantia Gelatinosa; Time Factors	2016
Spinal D-Serine Increases PKC-Dependent GluN1 Phosphorylation Contributing to the Sigma-1 Receptor-Induced Development of Mechanical Allodynia in a Mouse Model of Neuropathic Pain. The journal of pain, 2017, Volume: 18, Issue:4 Topics: Animals; D-Amino-Acid Oxidase; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Excitatory Amino Acid Agonists; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Nerve Tissue Proteins; Neuralgia; Phosphorylation; Physical Stimulation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Spinal Cord	2017
Leptin enhances NMDA-induced spinal excitation in rats: A functional link between adipocytokine and neuropathic pain. Pain, 2011, Volume: 152, Issue:6 Topics: Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; In Vitro Techniques; Leptin; Male; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Neuralgia; Pain Measurement; Patch-Clamp Techniques; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, N-Methyl-D-Aspartate; Sensory Receptor Cells; Signal Transduction; Spinal Cord; STAT3 Transcription Factor; Up-Regulation	2011
Antagonism of stimulation-produced analgesia by naloxone and N-methyl-D-aspartate: role of opioid and N-methyl-D-aspartate receptors. Human & experimental toxicology, 2012, Volume: 31, Issue:1 Topics: Analgesia; Analgesics, Opioid; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hot Temperature; Ketamine; Male; Morphine; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuralgia; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Sciatic Nerve	2012
Cellular prion protein protects from inflammatory and neuropathic pain. Molecular pain, 2011, Aug-16, Volume: 7 Topics: Animals; Inflammation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuralgia; Neuroprotective Agents; Nociception; Pain Threshold; Physical Stimulation; Prion Proteins; Prions	2011
The emergence of adolescent onset pain hypersensitivity following neonatal nerve injury. Molecular pain, 2012, Apr-24, Volume: 8 Topics: Age Factors; Animals; Disease Models, Animal; Hyperalgesia; Male; N-Methylaspartate; Neuralgia; Nociception; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley	2012
Analgesic antidepressants promote the responsiveness of locus coeruleus neurons to noxious stimulation: implications for neuropathic pain. Pain, 2012, Volume: 153, Issue:7 Topics: Analgesics; Animals; Antidepressive Agents; Disease Models, Animal; Locus Coeruleus; Male; N-Methylaspartate; Neuralgia; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord	2012
Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain. PloS one, 2013, Volume: 8, Issue:1 Topics: Animals; Carrageenan; Cell Count; Disease Models, Animal; Electrophysiological Phenomena; Female; Formaldehyde; Gene Deletion; Gene Expression Regulation; Gene Knockout Techniques; Hyperalgesia; Inflammation; Locomotion; Male; Mice; N-Methylaspartate; Neuralgia; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Receptor, EphB1; Sciatic Nerve; Signal Transduction	2013
Endogenous activation of presynaptic NMDA receptors enhances glutamate release from the primary afferents in the spinal dorsal horn in a rat model of neuropathic pain. The Journal of physiology, 2013, Apr-01, Volume: 591, Issue:7 Topics: Animals; Behavior, Animal; Excitatory Postsynaptic Potentials; Glutamic Acid; Ligation; Male; N-Methylaspartate; Neuralgia; Posterior Horn Cells; Protein Kinase C; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Nerves; Synapses	2013
Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: possible peripheral mechanisms. Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2 Topics: Action Potentials; Animals; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Ligation; Male; N-Methylaspartate; Neuralgia; Neurons, Afferent; Pain Measurement; Quinolones; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves; Time Factors	2005
D-cycloserine reduces neuropathic pain behavior through limbic NMDA-mediated circuitry. Pain, 2007, Volume: 132, Issue:1-2 Topics: Analgesics; Animals; Behavior, Animal; Cycloserine; Dose-Response Relationship, Drug; Hyperalgesia; Limbic System; N-Methylaspartate; Neuralgia; Pain Measurement; Rats; Rats, Sprague-Dawley; Treatment Outcome	2007
Diphenyl diselenide attenuates acute thermal hyperalgesia and persistent inflammatory and neuropathic pain behavior in mice. Brain research, 2007, Oct-17, Volume: 1175 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Benzene Derivatives; Bradykinin; Dinoprostone; Freund's Adjuvant; Glutamic Acid; Hyperalgesia; Inflammation Mediators; Male; Mice; N-Methylaspartate; Neuralgia; Neurogenic Inflammation; Nociceptors; Organoselenium Compounds; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Sciatic Neuropathy	2007
Contribution by DRt descending facilitatory pathways to maintenance of spinal neuron sensitization in rats. Brain research, 2008, Jan-10, Volume: 1188 Topics: Action Potentials; Animals; Disease Models, Animal; Efferent Pathways; Excitatory Amino Acid Antagonists; Functional Laterality; Hyperalgesia; Ligation; Male; Medulla Oblongata; N-Methylaspartate; Neural Inhibition; Neuralgia; Neurons, Afferent; Nociceptors; Pain Threshold; Peripheral Nervous System Diseases; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Reticular Formation; Sciatic Neuropathy; Spinothalamic Tracts	2008
Nerve growth factor induces mechanical allodynia associated with novel A fibre-evoked spinal reflex activity and enhanced neurokinin-1 receptor activation in the rat. Pain, 1995, Volume: 62, Issue:2 Topics: Analgesics; Animals; Evoked Potentials; Hindlimb; Indoles; Isoindoles; Lumbosacral Region; N-Methylaspartate; Nerve Fibers, Myelinated; Nerve Growth Factors; Neuralgia; Rats; Receptors, Neurokinin-1; Reflex; Spinal Cord; Stress, Mechanical	1995
PKCgamma contributes to a subset of the NMDA-dependent spinal circuits that underlie injury-induced persistent pain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jul-15, Volume: 21, Issue:14 Topics: Action Potentials; Animals; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Antagonists; Hyperalgesia; Isoenzymes; Mice; Mice, Knockout; Mustard Plant; N-Methylaspartate; Neuralgia; Pain Measurement; Physical Stimulation; Plant Extracts; Plant Oils; Posterior Horn Cells; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Spinal Cord	2001