n-methylaspartate has been researched along with Inflammation in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (16.13) | 18.2507 |
| 2000's | 28 (45.16) | 29.6817 |
| 2010's | 18 (29.03) | 24.3611 |
| 2020's | 6 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Cao, L; Chen, Y; Guan, H; Lin, Z; Lu, J; Xu, H; Zhang, S; Zhang, X; Zhang, Z; Zhou, C | 1 |
| Abdulzahir, A; Al Obaid, S; Alharbi, SA; Andrew Lin, KY; Ashoori, R; Awuah, KF; Azhdarpoor, A; Badalamenti, N; Basile, A; Benmatti, H; Berkani, M; Berkman, LF; Bontempo, P; Bruno, M; Capasso, L; Castagliuolo, G; Cha, JS; Chang, J; Chen, JT; Chen, WH; Cho, KW; Choi, J; Choi, YJ; Cianciullo, P; Cicio, A; Cousins, M; Di Napoli, M; Emadi, Z; Fakhreddine, B; Go, GW; Grabowski, DC; Hale, B; Ines, A; Jegede, O; Jeon, BH; Khan, MA; Kim, YM; Lakhdari, N; Lam, SS; Lari, AR; Lee, DY; Lee, IH; Lennertz, R; Maresca, V; Marouane, F; Mohammadpour, A; Mousavi Khaneghah, A; Moyo, KM; Napolitano, A; Nguyet, DVH; Park, SJ; Park, YK; Pearce, RA; Perkins, MG; Piacente, S; Renaud, M; Rezania, S; Rhee, GH; Samaei, MR; Siciliano, SD; Smaali, A; Soedono, S; Soltani, NS; Song, H; Song, YR; Taylor, MP; Unger, ES; Varcamonti, M; Wilson, SP; Yousefinejad, S; Zanfardino, A; Zhu, M | 1 |
| Chang, A; Chang, Y; Wang, SJ | 1 |
| Bai, L; Chen, S; Li, F; Liu, Y; Wang, X; Wang, Y; Wu, Y; Zhang, L | 1 |
| Dvoriantchikova, G; Fleishaker, M; Ivanov, D | 1 |
| Fan, H; Huang, J; Lai, X; Liu, A; Qiao, L; Shen, M; Wu, J; Yan, J | 1 |
| Fu, Y; Guo, LW; Li, J; Urabe, G; Zhao, L | 1 |
| Bernal-Chico, A; Brown, JM; Cipriani, R; Cravatt, BF; Hsu, KL; Manterola, A; Mato, S; Matute, C; Moreno-Rodríguez, M; Pérez-Samartín, A; Rodríguez-Puertas, R; Ruiz, A | 1 |
| Blackshaw, S; Campbell, WA; Fischer, AJ; Hoang, TV; Liu, X; Palazzo, I; Quan, N; Suarez, L; Todd, L; Volkov, L | 1 |
| Angelopoulou, E; Piperi, C | 1 |
| Abraham, WC; Bourne, K; Mockett, BG; Morris, GP; Ryan, MM; Tate, WP; Williams, JM | 1 |
| Abdelsaid, MA; Baldowski, BR; Bollinger, KE; El-Azab, MF; El-Remessy, AB; Matragoon, S; Mohamed, IN; Mysona, BA; Saul, A; Shanab, AY | 1 |
| Barron, S; Carter, M; Fields, L; Littleton, JM; Lutz, JA | 1 |
| Aoki, Y; Asano, D; Hayashi, I; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Ushikubo, H | 1 |
| Dekens, D; Dong, Y; Douwenga, W; Duffey, M; Eisel, UL; Fischer, R; Guenzi, E; Herrmann, A; Kontermann, RE; Maier, O; Naudé, PJ; Nyakas, C; Pfizenmaier, K; Van der Zee, EA | 1 |
| Atalay, M; Chung, HY; Jakus, J; Jung, KJ; Nyakas, C; Radák, Z; Sasvári, M; Stadler, K; Toldy, A | 1 |
| Hu, XD; Liu, XH; Xie, QJ; Yang, HB; Yang, X | 1 |
| Chan, MH; Chen, HH; Ko, CH; Lin, YC; Lin, YR | 1 |
| Boldyrev, AA; Cizkova, D; Mashkina, AP; Vanicky, I | 1 |
| Egea, J; Gadotti, VM; López, MG; Martins, DF; Mazzardo-Martins, L; Nascimento, FP; Rosa, AO; Santos, AR | 1 |
| Gong, S; Guo, SY; Jiang, XH; Peng, JM; Tao, J; Wu, GC; Xu, LS; Yu, XM; Zhu, Q | 1 |
| Gadotti, VM; Zamponi, GW | 1 |
| Cho, GS; Choi, IY; Choi, WJ; Hwang, S; Jeong, LS; Ju, C; Kim, WK; Lee, HW; Lee, JC | 1 |
| Gérard, F; Hansson, E | 1 |
| Battaglia, A; Cibert-Goton, V; Fredriksson, S; Gavazzi, I; Henkemeyer, M; Sears, T; Yuan, G | 1 |
| Hu, XD; Li, L; Liu, YN; Shi, L; Suo, ZW; Yang, X | 1 |
| Carlton, SM; Coggeshall, RE; Du, J; Zhou, S | 1 |
| Kuno, Y; Sato, E; Sato, I; Takano, M; Takano, Y | 1 |
| Arendt-Nielsen, L; Chen, J; Mørch, CD; You, HJ | 1 |
| Buchanan, AK; Nordell, VL; Scarborough, MM; Sohrabji, F | 1 |
| Baba, A; Hashimoto, H; Ito, S; Mabuchi, T; Matsumura, S; Minami, T; Muratani, T; Okuda-Ashitaka, E; Shintani, N | 1 |
| Iravani, MM; Jenner, P; Liu, L; Rose, S | 1 |
| Colica, C; Costa, N; Mollace, V; Muscoli, C; Nisticò, G; Nisticò, R; Palma, E; Rotiroti, D; Visalli, V | 1 |
| Souder, E | 1 |
| Corkill, DJ; Gomes-Leal, W; Picanço-Diniz, CW | 1 |
| Han, PL; Kim, JB; Kim, SW; Lee, JK; Lee, MH; Nam, K; Park, JS; Piao, CS; Sig Choi, J; Yu, YM | 1 |
| Bolton, C; Paul, C | 1 |
| Alehan, F; Erol, I; Melek, E; Muhteşem Ağildere, A; Ozyer, U | 1 |
| Barrett, AC; Lomas, LM; Lysle, DT; Picker, MJ; Terner, JM | 1 |
| Das, UN | 1 |
| Andrianov, GN; Nozdrachev, AD; Ryzhova, IV | 1 |
| Dos Santos, CD; Gomes-Leal, W; Picanço-Diniz, CW | 1 |
| Furuta, K; Ito, S; Mabuchi, T; Maeda, M; Minami, T; Soen, M; Suzuki, M; Tatsumi, S | 1 |
| Costa, AM; Dos Santos, CD; Gomes-Leal, W; Guimaraes-Silva, J; Lima, RR; Oliveira, JL; Picanço-Diniz, CW; Souza-Rodrigues, RD | 1 |
| Harms, A; Johnson, AB; Lewis, DK; Sohrabji, F; Stohlgren, S | 1 |
| Chang, YC; Kim, HW; Rao, JS; Rapoport, SI | 1 |
| Lücke, T; Neugebauer, V; Schaible, HG | 1 |
| Hunter, JC; Singh, L | 1 |
| Birch, PJ; Elliott, PJ; Harrison, SM; Smith, GD; Wiseman, J | 1 |
| Duggan, AW; Grubb, BD; Hope, PJ; Pubols, L; Riley, RC | 1 |
| Chao, CC; Ehrlich, L; Hu, S; Peterson, PK | 1 |
| Cashman, JN | 1 |
| Bong, GW; Firestein, GS; Rosengren, S | 1 |
| Bolton, SJ; Perry, VH | 1 |
| Dirig, DM; Yaksh, TL | 1 |
| Bacchi, A; Carlson, NG; Chen, J; Gahring, LC; Rogers, SW; Wieggel, WA | 1 |
| Galasso, JM; Martin, D; Silverstein, FS; Wang, P | 1 |
| Dubner, R; Hoffman, GE; Murphy, A; Ren, K; Wei1, F | 1 |
| Dubner, R; Guan, Y; Ren, K; Terayama, R | 1 |
| Brewer, KL; Fairbanks, CA; Grocholski, BM; Kehl, LJ; Kitto, KF; Nguyen, HO; Regunathan, S; Reis, DJ; Schreiber, KL; Shoeman, DW; Stone, LS; Wilcox, GL; Yezierski, RP; Yu, CG | 1 |
| Bär, KJ; Ebersberger, A; Klein, B; Schaible, HG; Vanegas, H; Vasquez, E | 1 |
5 review(s) available for n-methylaspartate and Inflammation
| Article | Year |
|---|---|
Beneficial Effects of Fingolimod in Alzheimer's Disease: Molecular Mechanisms and Therapeutic Potential.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Apoptosis; Blood-Brain Barrier; Brain-Derived Neurotrophic Factor; Drug Evaluation, Preclinical; Fingolimod Hydrochloride; Humans; Immunologic Factors; Inflammation; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neuroimmunomodulation; Neuroprotective Agents; Phosphotransferases (Alcohol Group Acceptor); Rats; Signal Transduction; Species Specificity; Sphingolipids; Sphingosine-1-Phosphate Receptors | 2019 |
Neuropathology in Alzheimer's disease: target of pharmacotherapy.
Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholinesterase Inhibitors; Disease Progression; Estrogens; Glutamic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; N-Methylaspartate; Neurofibrillary Tangles; Neuropharmacology; Neurotransmitter Agents | 2005 |
Glutamate receptors in neuroinflammatory demyelinating disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Humans; Inflammation; Models, Biological; Models, Chemical; Multiple Sclerosis; N-Methylaspartate; Receptors, Glutamate; Receptors, Kainic Acid | 2006 |
Is metabolic syndrome X a disorder of the brain with the initiation of low-grade systemic inflammatory events during the perinatal period?
Topics: Animals; Appetite Regulation; Arachidonic Acid; Brain; Diabetes Mellitus, Type 2; Docosahexaenoic Acids; Dopamine; Eicosapentaenoic Acid; Fatty Acids, Essential; Fatty Acids, Unsaturated; gamma-Aminobutyric Acid; Humans; Hypothalamus, Middle; Infant, Newborn; Inflammation; Insulin; Leptin; Metabolic Syndrome; N-Methylaspartate; Neurons; Qa-SNARE Proteins; Receptor, Insulin; Receptors, Retinoic Acid; Serotonin; Synapses | 2007 |
The mechanisms of action of NSAIDs in analgesia.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Humans; Inflammation; Lipoxygenase; Lipoxygenase Inhibitors; N-Methylaspartate; Pain; Prostaglandin-Endoperoxide Synthases; Rats | 1996 |
57 other study(ies) available for n-methylaspartate and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Context-dependent effects of inflammation on retina regeneration.
Topics: Animals; Cell Proliferation; Inflammation; Insulins; Mammals; N-Methylaspartate; Nerve Regeneration; Neuroglia; Retina; Zebrafish | 2022 |
Topics: Activities of Daily Living; Adult; Air Pollution, Indoor; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Azithromycin; Canada; Carbon; Caregivers; Chlorine; Cohort Studies; Corn Oil; COVID-19 Drug Treatment; Daphnia; Dust; Ecosystem; Electrodes; Environmental Monitoring; Fatty Acids; Female; Flavonoids; Fluorides; Glycosides; Greece; Groundwater; Hippocampus; Home Care Services; Humans; Infant; Inflammation; Iridoids; Lamiaceae; Longitudinal Studies; Male; Medicaid; Memory; Metals, Heavy; Methanol; Mice; Microplastics; Middle Aged; N-Methylaspartate; Neural Networks, Computer; Nitrates; Nitrogen Oxides; Nylons; Obesity; Oleic Acid; Olive Oil; Oxidation-Reduction; Phosphorus; Place Cells; Plant Components, Aerial; Plant Extracts; Plastics; Polyesters; Polyurethanes; Prevalence; Quinic Acid; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Risk Assessment; Sodium Chloride; Soil; Soil Pollutants; Stachys; Staphylococcus aureus; Stearic Acids; Superoxide Dismutase; U937 Cells; United States; Water; Water Pollutants, Chemical; Young Adult | 2021 |
Rutin prevents seizures in kainic acid-treated rats: evidence of glutamate levels, inflammation and neuronal loss modulation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Transport Systems; Animals; Anti-Inflammatory Agents; Carbamazepine; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Hippocampus; HMGB1 Protein; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Kainic Acid; N-Methylaspartate; Rats; Receptors, Interleukin-1; Rutin; Seizures; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2022 |
Glutamate ionotropic receptor NMDA type subunit 1: A novel potential protein target of dapagliflozin against renal interstitial fibrosis.
Topics: Animals; Fibrosis; Glutamates; Humans; Inflammation; Kidney; Mice; N-Methylaspartate; Renal Insufficiency, Chronic; Sodium-Glucose Transporter 2 Inhibitors | 2023 |
Molecular mechanisms of NMDA excitotoxicity in the retina.
Topics: Animals; Free Radicals; Inflammation; Iron; Mice; N-Methylaspartate; Necrosis; Retina; Retinal Diseases | 2023 |
Simvastatin Improves Behavioral Disorders and Hippocampal Inflammatory Reaction by NMDA-Mediated Anti-inflammatory Function in MPTP-Treated Mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dopaminergic Neurons; Hippocampus; Inflammation; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Parkinson Disease; Simvastatin | 2020 |
Epigenetic intervention with a BET inhibitor ameliorates acute retinal ganglion cell death in mice.
Topics: Animals; Apoptosis; Azepines; Cell Count; Cytokines; Epigenesis, Genetic; Female; Gene Expression Regulation; Inflammation; Male; Mice, Inbred C57BL; N-Methylaspartate; Nuclear Proteins; Retinal Ganglion Cells; Triazoles | 2017 |
Re-examining the potential of targeting ABHD6 in multiple sclerosis: Efficacy of systemic and peripherally restricted inhibitors in experimental autoimmune encephalomyelitis.
Topics: Animals; Benzoates; Biphenyl Compounds; Brain; Calcium; Carbamates; Cells, Cultured; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation; Mice; Mitochondria; Molecular Targeted Therapy; Monoacylglycerol Lipases; N-Methylaspartate; Neural Conduction; Piperidines; Pyramidal Tracts; Receptor, Cannabinoid, CB1; Triazoles | 2018 |
Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina.
Topics: Animals; Excitatory Amino Acid Agonists; Inflammation; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout; Microglia; N-Methylaspartate; Neuroprotection; Neurotoxins; Receptors, Interleukin-1 Type I; Retina | 2019 |
Time-dependent changes in gene expression induced by secreted amyloid precursor protein-alpha in the rat hippocampus.
Topics: Amyloid beta-Protein Precursor; Animals; Apoptosis; Cell Survival; Female; HEK293 Cells; Hippocampus; Humans; In Vitro Techniques; Inflammation; Male; N-Methylaspartate; Neurogenesis; Neuroprotective Agents; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors; Transcription, Genetic; Transcriptome | 2013 |
Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury.
Topics: Adult; Aged; Animals; Apoptosis; Carrier Proteins; Cells, Cultured; Ependymoglial Cells; Female; Glaucoma, Open-Angle; Humans; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; N-Methylaspartate; Neurotoxicity Syndromes; Retina; Thioredoxin-Disulfide Reductase; Thioredoxins; Tumor Necrosis Factor-alpha; Tyrosine; Vascular System Injuries | 2014 |
Altered relation between lipopolysaccharide-induced inflammatory response and excitotoxicity in rat organotypic hippocampal slice cultures during ethanol withdrawal.
Topics: Animals; Drug Interactions; Ethanol; Hippocampus; Inflammation; Lipopolysaccharides; Microglia; N-Methylaspartate; Neurons; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome; Tissue Culture Techniques; Tumor Necrosis Factor-alpha | 2015 |
Protective Effects of Everolimus against N-Methyl-D-aspartic Acid-Induced Retinal Damage in Rats.
Topics: Animals; Disease Models, Animal; Everolimus; Extracellular Signal-Regulated MAP Kinases; In Situ Nick-End Labeling; Inflammation; Intravitreal Injections; Leukocyte Common Antigens; Male; N-Methylaspartate; Neuroprotective Agents; Phosphorylation; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Retina; Retinal Diseases; Retinal Ganglion Cells; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration.
Topics: Animals; Antibodies; Basal Nucleus of Meynert; Carrier Proteins; Cell Death; Cholinergic Neurons; HEK293 Cells; Humans; Inflammation; Mice; N-Methylaspartate; Nerve Degeneration; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2016 |
The beneficial effects of nettle supplementation and exercise on brain lesion and memory in rat.
Topics: Animals; Antioxidants; Avoidance Learning; Behavior, Animal; Brain; Cerebellum; Free Radicals; Inflammation; Male; Memory; N-Methylaspartate; Neurodegenerative Diseases; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Wistar; Swimming; Urtica dioica | 2009 |
Peripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn.
Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Functional Laterality; Gene Expression Regulation; Inflammation; Isoquinolines; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pain Measurement; Posterior Horn Cells; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Serine; Spinal Cord; Subcellular Fractions; Sulfonamides; Synapses | 2009 |
Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain.
Topics: Analgesics; Animals; Anti-Infective Agents; Biphenyl Compounds; Dinoprostone; Excitatory Amino Acid Agents; Glycine; Immunohistochemistry; Inflammation; Lignans; Male; Mice; N-Methylaspartate; Phenylacetates; Proto-Oncogene Proteins c-fos; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2009 |
NMDA receptors are expressed in lymphocytes activated both in vitro and in vivo.
Topics: Animals; Cell Movement; Humans; Inflammation; Interferon-gamma; Lymphocyte Activation; N-Methylaspartate; Phytohemagglutinins; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; T-Lymphocytes | 2010 |
The antinociceptive effects of AR-A014418, a selective inhibitor of glycogen synthase kinase-3 beta, in mice.
Topics: Abdominal Pain; Aggression; Analgesics; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azides; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Formaldehyde; Glutamic Acid; Glycogen Synthase Kinase 3; Inflammation; Male; Mice; N-Methylaspartate; Pain Measurement; Sugar Acids; Thiazoles; Urea; Xylose | 2011 |
Enhanced NMDA receptor NR1 phosphorylation and neuronal activity in the arcuate nucleus of hypothalamus following peripheral inflammation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arcuate Nucleus of Hypothalamus; Blotting, Western; Dizocilpine Maleate; Glutamic Acid; Inflammation; Male; N-Methylaspartate; Phosphorylation; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 2011 |
Cellular prion protein protects from inflammatory and neuropathic pain.
Topics: Animals; Inflammation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuralgia; Neuroprotective Agents; Nociception; Pain Threshold; Physical Stimulation; Prion Proteins; Prions | 2011 |
A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats.
Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Brain Infarction; Brain Injuries; Brain Ischemia; Cell Movement; Chemokine CCL2; Glucose; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Microglia; Monocytes; N-Methylaspartate; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; rho GTP-Binding Proteins; Thionucleosides; Tumor Necrosis Factor-alpha | 2011 |
Inflammatory activation enhances NMDA-triggered Ca2+ signalling and IL-1β secretion in primary cultures of rat astrocytes.
Topics: Animals; Astrocytes; Calcium Signaling; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Immunohistochemistry; Inflammation; Interleukin-1beta; Lipopolysaccharides; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate | 2012 |
Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain.
Topics: Animals; Carrageenan; Cell Count; Disease Models, Animal; Electrophysiological Phenomena; Female; Formaldehyde; Gene Deletion; Gene Expression Regulation; Gene Knockout Techniques; Hyperalgesia; Inflammation; Locomotion; Male; Mice; N-Methylaspartate; Neuralgia; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Receptor, EphB1; Sciatic Nerve; Signal Transduction | 2013 |
Inhibition of protein tyrosine phosphatases in spinal dorsal horn attenuated inflammatory pain by repressing Src signaling.
Topics: Animals; Freund's Adjuvant; Hyperalgesia; Inflammation; Injections, Spinal; Male; N-Methylaspartate; Organometallic Compounds; Pain Threshold; Phenanthrolines; Phosphorylation; Posterior Horn Cells; Protein Tyrosine Phosphatases; Rats; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Vanadates | 2013 |
N-methyl-D-aspartate-induced excitation and sensitization of normal and inflamed nociceptors.
Topics: Action Potentials; Animals; Axons; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Hindlimb; Hot Temperature; In Vitro Techniques; Inflammation; Male; N-Methylaspartate; Nociceptors; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Skin; Stimulation, Chemical; Time Factors | 2003 |
Involvement of spinal tyrosine kinase in inflammatory and N-methyl-D-aspartate-induced hyperalgesia in rats.
Topics: Animals; Carrageenan; Dizocilpine Maleate; Hot Temperature; Hyperalgesia; Inflammation; Injections, Spinal; Kaolin; Male; N-Methylaspartate; Pain; Pain Measurement; Phenols; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2003 |
Role of central NMDA versus non-NMDA receptor in spinal withdrawal reflex in spinal anesthetized rats under normal and hyperexcitable conditions.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Anesthesia; Animals; Bee Venoms; Central Nervous System; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hindlimb; Inflammation; Male; Muscle, Skeletal; N-Methylaspartate; Pain Measurement; Pain Threshold; Physical Stimulation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reflex; Spinal Cord; Spinal Cord Injuries | 2003 |
Differential effects of estrogen in the injured forebrain of young adult and reproductive senescent animals.
Topics: Aging; Analysis of Variance; Animals; Diagonal Band of Broca; Enzyme-Linked Immunosorbent Assay; Estrogen Replacement Therapy; Estrogens; Excitatory Amino Acid Agonists; Female; Inflammation; Interleukin-1; Interleukin-10; Lectins; Microglia; N-Methylaspartate; Nerve Growth Factor; Olfactory Bulb; Ovariectomy; Prosencephalon; Rats; Reproduction | 2003 |
Pituitary adenylate cyclase-activating polypeptide is required for the development of spinal sensitization and induction of neuropathic pain.
Topics: Animals; Cell Membrane; Inflammation; Mice; Mice, Knockout; N-Methylaspartate; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Transport; Spinal Cord | 2004 |
Role of inducible nitric oxide synthase in N-methyl-d-aspartic acid-induced strio-nigral degeneration.
Topics: Animals; Functional Laterality; Guanidines; Immunohistochemistry; Inflammation; Interneurons; Male; Motor Activity; N-Methylaspartate; NADPH Dehydrogenase; Neostriatum; Nerve Degeneration; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Tyrosine | 2004 |
The effect of inflammatory stimuli on NMDA-related activation of glutamine synthase in human cultured astroglial cells.
Topics: Astrocytes; Cell Line; Enzyme Activation; Glutamate-Ammonia Ligase; Humans; Inflammation; Male; Middle Aged; N-Methylaspartate | 2005 |
Systematic analysis of axonal damage and inflammatory response in different white matter tracts of acutely injured rat spinal cord.
Topics: Animals; Axons; Cell Count; Excitatory Amino Acid Agonists; Immunohistochemistry; Inflammation; Macrophages; Male; Microglia; Microscopy, Electron, Transmission; N-Methylaspartate; Neurotoxins; Neutrophils; Perfusion; Rats; Rats, Wistar; Spinal Cord Injuries | 2005 |
HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain.
Topics: Animals; Blotting, Northern; Blotting, Western; Brain; Cell Death; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; High Mobility Group Proteins; HMGB1 Protein; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Microglia; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Time Factors; Transfection | 2006 |
+H-proton-magnetic resonance spectroscopic findings in a patient with acute hemicerebellitis presenting without localized signs: a case report.
Topics: Acute Disease; Adolescent; Aspartic Acid; Cerebellar Diseases; Choline; Cranial Fossa, Posterior; Creatine; Female; Humans; Inflammation; Magnetic Resonance Imaging; N-Methylaspartate; Protons | 2006 |
Sex differences in the potency of kappa opioids and mixed-action opioids administered systemically and at the site of inflammation against capsaicin-induced hyperalgesia in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hyperalgesia; Inflammation; Injections, Intraventricular; Injections, Subcutaneous; Male; N-Methylaspartate; Pain; Pain Measurement; Rats; Rats, Inbred F344; Receptors, Opioid; Sex Factors | 2007 |
The role of defensins in the excitability of the peripheral vestibular system in the frog: evidence for the presence of communication between the immune and nervous systems.
Topics: Acetylcholine; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Defensins; Animals; Atropine; Cholinergic Antagonists; Cycloleucine; Defensins; Dose-Response Relationship, Drug; Glutamic Acid; Humans; Immune System; In Vitro Techniques; Inflammation; Kainic Acid; N-Methylaspartate; Naloxone; Narcotic Antagonists; Neuroimmunomodulation; Neurons, Afferent; Rabbits; Rana temporaria; Receptors, Cholinergic; Receptors, Glutamate; Receptors, Opioid; Semicircular Canals; Synaptic Transmission; Vestibule, Labyrinth | 2007 |
Differential patterns of inflammatory response, axonal damage and myelin impairment following excitotoxic or ischemic damage to the trigeminal spinal nucleus of adult rats.
Topics: Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Axons; Brain Ischemia; Cell Count; Demyelinating Diseases; Ectodysplasins; Endothelin-1; Inflammation; Male; Myelin Basic Protein; N-Methylaspartate; Neurotoxins; Rats; Rats, Wistar; Time Factors; Trigeminal Nucleus, Spinal | 2007 |
A synthetic kainoid, (2S,3R,4R)-3-carboxymethyl-4-(phenylthio)pyrrolidine-2-carboxylic acid (PSPA-1) serves as a novel anti-allodynic agent for neuropathic pain.
Topics: Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hyperalgesia; Immunohistochemistry; Inflammation; Kainic Acid; Mice; Mononeuropathies; N-Methylaspartate; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Nociceptors; Pain; Spinal Cord; Time Factors | 2007 |
Diffuse axonal damage, myelin impairment, astrocytosis and inflammatory response following microinjections of NMDA into the rat striatum.
Topics: Animals; Axons; Corpus Striatum; Excitatory Amino Acid Agonists; Gliosis; Immunohistochemistry; Inflammation; Macrophages; Male; Myelin Sheath; N-Methylaspartate; Neutrophils; Perfusion; Rats; Rats, Wistar | 2008 |
Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats.
Topics: Aging; Animals; Astrocytes; Calcium-Binding Proteins; CD11b Antigen; Cells, Cultured; Drug Interactions; Estrogens; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Inflammation; Lipopolysaccharides; Microfilament Proteins; Microtubule-Associated Proteins; N-Methylaspartate; Olfactory Bulb; Ovariectomy; Rats; Receptors, Estrogen; Tumor Necrosis Factor-alpha | 2008 |
Chronic NMDA administration increases neuroinflammatory markers in rat frontal cortex: cross-talk between excitotoxicity and neuroinflammation.
Topics: Animals; Biomarkers; Blotting, Western; Cytokines; Frontal Lobe; Inflammation; Male; N-Methylaspartate; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2008 |
Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons.
Topics: Acute Disease; Afferent Pathways; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arthritis; Cycloleucine; Inflammation; Knee Joint; Male; N-Methylaspartate; Neurons; Pain; Pressure; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Role of excitatory amino acid receptors in the mediation of the nociceptive response to formalin in the rat.
Topics: Analgesics; Animals; Formaldehyde; Inflammation; Male; N-Methylaspartate; Nociceptors; Pain Measurement; Pipecolic Acids; Pyrrolidinones; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1994 |
Pre treatment with MK-801, a non-competitive NMDA antagonist, prevents development of mechanical hyperalgesia in a rat model of chronic neuropathy, but not in a model of chronic inflammation.
Topics: Animals; Chronic Disease; Dizocilpine Maleate; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; N-Methylaspartate; Nervous System Diseases; Nociceptors; Physical Stimulation; Rats; Receptors, N-Methyl-D-Aspartate; Sciatic Nerve | 1994 |
The burst-like firing of spinal neurons in rats with peripheral inflammation is reduced by an antagonist of N-methyl-D-aspartate.
Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Inflammation; Iontophoresis; Male; Membrane Potentials; Mesencephalon; N-Methylaspartate; Neurons; Nociceptors; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Synapses | 1996 |
Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors.
Topics: 2-Amino-5-phosphonovalerate; Astrocytes; Biological Transport; Biomarkers; Cell Death; Cells, Cultured; Dizocilpine Maleate; Drug Synergism; Enzyme Induction; Excitatory Amino Acid Antagonists; Glutamate-Ammonia Ligase; Glutamic Acid; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; L-Lactate Dehydrogenase; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sialoglycoproteins; Tumor Necrosis Factor-alpha | 1995 |
Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-D-aspartate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Inflammatory Agents; Carrageenan; Catheterization; Central Nervous System; Dexamethasone; Excitatory Amino Acid Antagonists; Inflammation; N-Methylaspartate; Neutrophils; Peroxidase; Phenethylamines; Propionates; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Skin; Spinal Cord; Theobromine | 1996 |
Differential blood-brain barrier breakdown and leucocyte recruitment following excitotoxic lesions in juvenile and adult rats.
Topics: Aging; Animals; Astrocytes; Biomarkers; Blood-Brain Barrier; Brain; Excitatory Amino Acid Agonists; Immunoenzyme Techniques; Inflammation; Kainic Acid; Leukocytes; Male; Microglia; N-Methylaspartate; Nerve Degeneration; Permeability; Rats; Rats, Wistar; Time Factors | 1998 |
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2 | 1999 |
Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Immune Sera; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Interleukin-6; Mice; N-Methylaspartate; Nerve Growth Factors; Neuroimmunomodulation; Neurons; Neurotoxins; Nicotine; Nicotinic Antagonists; Receptors, Interleukin-1; Sialoglycoproteins; Signal Transduction; Tumor Necrosis Factor-alpha | 1999 |
Inhibition of TNF-alpha can attenuate or exacerbate excitotoxic injury in neonatal rat brain.
Topics: Animals; Animals, Newborn; Atrophy; Brain; Brain Injuries; Carrier Proteins; Corpus Striatum; Disease Models, Animal; Drug Synergism; Excitatory Amino Acid Agonists; Hippocampus; Inflammation; N-Methylaspartate; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha | 2000 |
Progesterone attenuates persistent inflammatory hyperalgesia in female rats: involvement of spinal NMDA receptor mechanisms.
Topics: Animals; Estrus; Excitatory Amino Acid Agonists; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Lactation; N-Methylaspartate; Ovariectomy; Pregnancy; Progesterone; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 2000 |
Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation.
Topics: Animals; Behavior, Animal; Efferent Pathways; Electric Stimulation; Excitatory Amino Acid Agonists; Hot Temperature; Inflammation; Male; Medulla Oblongata; N-Methylaspartate; Neural Inhibition; Neuronal Plasticity; Nociceptors; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Glutamate; Stimulation, Chemical; Synaptic Transmission | 2000 |
Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury.
Topics: Agmatine; Analgesics; Animals; Immunohistochemistry; Inflammation; Male; Mice; N-Methylaspartate; Pain; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2000 |
Spinal prostaglandins are involved in the development but not the maintenance of inflammation-induced spinal hyperexcitability.
Topics: Action Potentials; Administration, Topical; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carrageenan; Dinoprostone; Excitatory Amino Acid Agonists; Hindlimb; Hyperesthesia; Indomethacin; Inflammation; Injections, Spinal; Iontophoresis; Joints; Kaolin; Male; N-Methylaspartate; Nociceptors; Physical Stimulation; Posterior Horn Cells; Prostaglandins; Rats; Rats, Wistar; Spinal Cord | 2001 |