n-methylaspartate has been researched along with Glaucoma in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 11 (31.43) | 29.6817 |
| 2010's | 15 (42.86) | 24.3611 |
| 2020's | 5 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Brahma, MM; Goshima, Y; Harada, T; Namekata, K; Ohshima, T; Takahashi, K | 1 |
| Ji, D; Li, H; Liu, M; Xia, X; Yang, R | 1 |
| An, Y; Ding, L; Li, H; Song, S; Wang, C; Xia, X; Xia, Z; Zhou, X | 1 |
| Behar-Cohen, F; Bigot, K; Bordet, T; Fan, Y; Inman, DM; Jaworski, T; Kodati, B; Nsiah, NY; Pappenhagen, N; Picard, E; Youale, J | 1 |
| Basavarajappa, D; Chitranshi, N; Graham, SL; Gupta, V; Klistorner, A; Mirzaei, M; Palanivel, V; Vander Wall, R; Viswanathan, D; You, Y | 1 |
| Chan, TTH; Chan, WY; Feng, B; Gao, L; Hobbs, R; Hou, HW; Jiang, X; Lee, TL; Lee, WT; Leung, KS; Li, I; Li, K; Liao, J; Liu, YH; Luk, CS; Mak, HK; Ng, JKW; Ng, TK; Qi, H; Qian, Y; Rudd, JA; Suen, HC | 1 |
| Liu, S; Luo, X; Nawy, S; Shen, Y | 1 |
| Cui, H; Jin, Y; Li, Q; Li, R; Sun, X; Zhu, H | 1 |
| Choi, SJ; Jo, H; Jung, SH | 1 |
| Endo, K; Fujisaka, S; Hori, M; Imai, N; Kagami, N; Koide, R; Matkovits, A; Nakamachi, T; Ohtaki, H; Seki, T; Shioda, S; Takahashi, H; Tobe, K; Tsuchida, M; Tsuchikawa, D; Usui, I; Wada, Y; Yoshikawa, A | 1 |
| Ishii, K; Kurauchi, Y; Mori, A; Nakahara, T; Sakamoto, K | 1 |
| Ahn, HR; Jang, H; Jung, SH; Kim, CY; Kim, KA; Lee, CY; Lee, HJ; Nho, CW; Pan, CH | 1 |
| Cui, Q; Pickard, GE; Ren, C; So, KF; Sollars, PJ | 1 |
| Ellisman, MH; Hoshijima, M; Ju, WK; Kim, KY; Lukas, TJ; Noh, YH; Perkins, GA; Weinreb, RN | 1 |
| Agey, P; Dong, CJ; Guo, Y; Hare, WA; Wheeler, L | 1 |
| Cooper, NG; Fan, W; Laabich, A; Wang, X | 1 |
| Barnett, EM; Chang, Q; Maxwell, D; Piwnica-Worms, D; Zhang, X | 1 |
| Chou, CL; Kasanuki, JM; Nagasaki, T; Tosi, J; Tsang, SH; Wang, NK; Zhao, J | 1 |
| Broadway, DC; Niyadurupola, N; Osborne, A; Sanderson, J; Sidaway, P | 1 |
| Casson, RJ; Chidlow, G; Ebneter, A; Wood, JP | 1 |
| Hangai, M; Ikeda, HO; Kakizuka, A; Muraoka, Y; Nakano, N; Toda, Y; Yoshimura, N | 1 |
| Caprioli, J; Kwong, JM; Kyung, H; Piri, N; Quan, A | 1 |
| Ishii, K; Mori, A; Nakahara, T; Sakamoto, K; Tsuda, Y; Ueda, K | 1 |
| Bui, BV; Cioffi, GA; Cull, G; Fortune, B; Wang, L | 1 |
| Baldridge, WH; Chauhan, BC; Hartwick, AT; Zhang, X | 1 |
| Harrison, WW; Malinovsky, VE; Viswanathan, S | 1 |
| Danias, J; Filippopoulos, T; Mittag, T; Reichstein, D; Ren, L | 1 |
| Fan, SS; Huang, SY; Lai, CC; Lee Chao, PD; Lin, HJ; Tsai, FJ; Tsai, Y; Wan, L | 1 |
| Frishman, LJ; Ktonas, P; Rangaswamy, N; Zhou, W | 1 |
| Dreyer, EB | 1 |
| Adachi, K; Akaike, A; Kaneda, K | 1 |
| Flanagan, JG | 1 |
| Dreyer, EB; Gorla, MS; Vorwerk, CK | 1 |
| Barnes, G; Frishman, LJ; Harwerth, RS; Li, Y; Robson, JG; Saszik, S; Smith, EL; Viswanathan, S | 1 |
| Melena, J; Osborne, NN; Stanton, D | 1 |
7 review(s) available for n-methylaspartate and Glaucoma
| Article | Year |
|---|---|
Neurovascular interactions in the retina: physiological and pathological roles.
Topics: Angiotensin II; Catecholamines; Cell Communication; Diabetic Retinopathy; Disease Progression; Drug Discovery; Endothelin Receptor Antagonists; Endothelin-1; Glaucoma; Homeostasis; Molecular Targeted Therapy; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Potassium Channels, Calcium-Activated; Receptors, GABA; Retina; Retinal Diseases; Retinal Vessels | 2013 |
The injury resistant ability of melanopsin-expressing intrinsically photosensitive retinal ganglion cells.
Topics: Animals; Glaucoma; N-Methylaspartate; Optic Nerve Injuries; Retinal Ganglion Cells; Rod Opsins; Visual Pathways | 2015 |
The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells.
Topics: Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Caspase 3; Cell Death; Cell Survival; Excitatory Amino Acid Antagonists; Glaucoma; Humans; Isoenzymes; N-Methylaspartate; Nerve Growth Factors; Peptides; Photoperiod; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Signal Transduction | 2008 |
A proposed role for excitotoxicity in glaucoma.
Topics: Animals; Glaucoma; Glutamic Acid; Humans; N-Methylaspartate; Retinal Ganglion Cells; Vitreous Body | 1998 |
[Techniques for evaluating neuronal death of the retina in vitro and in vivo].
Topics: Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glaucoma; Glutamates; Humans; Injections; Ischemia; N-Methylaspartate; Neurons; Neuroprotective Agents; Rats; Retina; Retinal Vessels; Vitreous Body | 1998 |
Glaucoma update: epidemiology and new approaches to medical management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Axons; Glaucoma; Humans; Middle Aged; N-Methylaspartate; Optic Nerve; Prevalence; Prostaglandins, Synthetic | 1998 |
An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy.
Topics: Animals; Apoptosis; Enzyme Inhibitors; Glaucoma; Glutamic Acid; Humans; Intraocular Pressure; N-Methylaspartate; Neuroprotective Agents; Nitric Oxide Synthase; Optic Nerve Diseases; Retinal Ganglion Cells; Vitreous Body | 1999 |
28 other study(ies) available for n-methylaspartate and Glaucoma
| Article | Year |
|---|---|
Genetic inhibition of collapsin response mediator protein-2 phosphorylation ameliorates retinal ganglion cell death in normal-tension glaucoma models.
Topics: Animals; Disease Models, Animal; Glaucoma; Glutamic Acid; Intercellular Signaling Peptides and Proteins; Mice; N-Methylaspartate; Nerve Tissue Proteins; Phosphorylation; Retinal Ganglion Cells | 2022 |
GSK872 and necrostatin-1 protect retinal ganglion cells against necroptosis through inhibition of RIP1/RIP3/MLKL pathway in glutamate-induced retinal excitotoxic model of glaucoma.
Topics: Animals; Apoptosis; Caspase 1; Eosine Yellowish-(YS); Glaucoma; Glutamic Acid; Glutathione; Hematoxylin; Inflammasomes; Interleukin-1beta; Lactate Dehydrogenases; Mice; N-Methylaspartate; Necroptosis; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Retinal Ganglion Cells | 2022 |
The neuroprotective effect of melatonin in glutamate excitotoxicity of R28 cells and mouse retinal ganglion cells.
Topics: Animals; Glaucoma; Glutamic Acid; Melatonin; Mice; N-Methylaspartate; Neuroprotective Agents; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells | 2022 |
Neuroprotective Effects of Transferrin in Experimental Glaucoma Models.
Topics: Animals; Disease Models, Animal; Glaucoma; Hypoxia; Intraocular Pressure; Iron; N-Methylaspartate; Neuroprotective Agents; Ocular Hypertension; Rats; Transferrin | 2022 |
Anti-inflammatory Effects of Siponimod in a Mouse Model of Excitotoxicity-Induced Retinal Injury.
Topics: Animals; Anti-Inflammatory Agents; Glaucoma; Mice; N-Methylaspartate; Neuroinflammatory Diseases; Receptors, N-Methyl-D-Aspartate; Retina | 2023 |
Transplantation of Retinal Ganglion Cells Derived from Male Germline Stem Cell as a Potential Treatment to Glaucoma.
Topics: Adult Germline Stem Cells; Animals; Biomarkers; Cell Differentiation; Cell- and Tissue-Based Therapy; Disease Models, Animal; Embryonic Stem Cells; Gene Expression; Genes, Reporter; Glaucoma; Green Fluorescent Proteins; Homeodomain Proteins; Intravitreal Injections; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Octamer Transcription Factor-3; Primary Cell Culture; Retina; Retinal Ganglion Cells; Testis; Transcription Factor Brn-3B | 2019 |
Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle Proteins; Dendrites; Disease Models, Animal; Electroretinography; Glaucoma; HEK293 Cells; Humans; Male; Mice, Inbred C57BL; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Binding; Protein Kinase C-alpha; Proteolysis; Receptors, N-Methyl-D-Aspartate; Retinal Bipolar Cells; Retinal Cone Photoreceptor Cells; Retinal Ganglion Cells; Retinal Rod Photoreceptor Cells; Ubiquitin | 2019 |
MiR-93-5p targeting PTEN regulates the NMDA-induced autophagy of retinal ganglion cells via AKT/mTOR pathway in glaucoma.
Topics: Animals; Autophagy; Cell Survival; Disease Models, Animal; Female; Glaucoma; Male; MicroRNAs; N-Methylaspartate; Protein Binding; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rats, Sprague-Dawley; Retinal Ganglion Cells; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2018 |
Protective effects of a compound isolated from Alnus japonica on oxidative stress-induced death in transformed retinal ganglion cells.
Topics: Alnus; Animals; Apoptosis; Buthionine Sulfoximine; Catechols; Cell Survival; Diarylheptanoids; DNA Nucleotidylexotransferase; Glaucoma; Glutamic Acid; In Situ Nick-End Labeling; Lipid Peroxidation; Male; N-Methylaspartate; Neuroprotective Agents; Nitroprusside; Oxidative Stress; Plant Extracts; Propidium; Rats; Rats, Sprague-Dawley; Retina; Retinal Ganglion Cells; Thiobarbituric Acid Reactive Substances | 2013 |
PACAP attenuates NMDA-induced retinal damage in association with modulation of the microglia/macrophage status into an acquired deactivation subtype.
Topics: Animals; Cell Proliferation; Glaucoma; Interleukin-10; Intravitreal Injections; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Microglia; N-Methylaspartate; Neuroprotective Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Retina; Retinal Ganglion Cells; RNA, Messenger; Transforming Growth Factor beta1 | 2013 |
Hydroxycinnamic acids in Crepidiastrum denticulatum protect oxidative stress-induced retinal damage.
Topics: Animals; Apoptosis; Asteraceae; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Disease Models, Animal; Glaucoma; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Nerve Crush; Neuroprotective Agents; Optic Nerve; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Retinal Diseases; Succinates | 2014 |
Increased mitochondrial fission and volume density by blocking glutamate excitotoxicity protect glaucomatous optic nerve head astrocytes.
Topics: Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Animals; Astrocytes; Cell Count; Cells, Cultured; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glaucoma; Glutamic Acid; Humans; Intraocular Pressure; Memantine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Mitochondria; Mitochondrial Dynamics; N-Methylaspartate; Optic Disk; Oxidoreductases Acting on CH-NH Group Donors; Retinal Ganglion Cells | 2015 |
Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Signaling; Disease Models, Animal; Excitatory Amino Acid Agonists; Glaucoma; Male; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Quinoxalines; Rabbits; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Ganglion Cells; Rolipram | 2008 |
Single-cell imaging of retinal ganglion cell apoptosis with a cell-penetrating, activatable peptide probe in an in vivo glaucoma model.
Topics: Animals; Apoptosis; Cytological Techniques; Glaucoma; In Situ Nick-End Labeling; Male; N-Methylaspartate; Peptides; Rats; Retinal Ganglion Cells | 2009 |
Rapid and noninvasive imaging of retinal ganglion cells in live mouse models of glaucoma.
Topics: Animals; Cell Count; Cell Death; Disease Models, Animal; Fluorescence; Fundus Oculi; Glaucoma; Green Fluorescent Proteins; Intraocular Pressure; Kainic Acid; Mice; Molecular Imaging; N-Methylaspartate; Neurotoxins; Retinal Ganglion Cells; Thy-1 Antigens; Time Factors | 2010 |
The development of human organotypic retinal cultures (HORCs) to study retinal neurodegeneration.
Topics: Apoptosis; Cell Hypoxia; Cells, Cultured; Glaucoma; Humans; Immunohistochemistry; N-Methylaspartate; Nerve Degeneration; Retinal Degeneration; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thy-1 Antigens; Tissue Culture Techniques; Visual Pathways | 2011 |
The optic nerve head is the site of axonal transport disruption, axonal cytoskeleton damage and putative axonal regeneration failure in a rat model of glaucoma.
Topics: Amyloid beta-Protein Precursor; Animals; Axonal Transport; Cholera Toxin; Cytoskeleton; Disease Models, Animal; Excitatory Amino Acid Agonists; Gene Expression Regulation; Glaucoma; HSP27 Heat-Shock Proteins; Myelin Basic Protein; N-Methylaspartate; Nerve Regeneration; Nerve Tissue Proteins; Optic Disk; Organic Chemicals; Rats; Retinal Ganglion Cells; RNA, Messenger; Time Factors | 2011 |
Longitudinal and simultaneous imaging of retinal ganglion cells and inner retinal layers in a mouse model of glaucoma induced by N-methyl-D-aspartate.
Topics: Amacrine Cells; Animals; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agonists; Glaucoma; Green Fluorescent Proteins; Longitudinal Studies; Male; Mice; Mice, Transgenic; N-Methylaspartate; Ophthalmoscopy; Optic Disk; Reproducibility of Results; Retinal Ganglion Cells; Tomography, Optical Coherence | 2011 |
Quantitative analysis of retinal ganglion cell survival with Rbpms immunolabeling in animal models of optic neuropathies.
Topics: Animals; Biomarkers; Cell Count; Cell Survival; Disease Models, Animal; Dizocilpine Maleate; Fluorescent Antibody Technique, Indirect; Glaucoma; Intraocular Pressure; Male; N-Methylaspartate; Nerve Crush; Optic Nerve Diseases; Optic Nerve Injuries; Rats; Rats, Inbred BN; Rats, Wistar; Retinal Ganglion Cells; RNA-Binding Proteins; Stilbamidines; Tonometry, Ocular; Tubulin | 2011 |
Effect of nafamostat on N-methyl-D-aspartate-induced retinal neuronal and capillary degeneration in rats.
Topics: Animals; Basement Membrane; Benzamidines; Capillaries; Diabetic Neuropathies; Excitatory Amino Acid Agonists; Glaucoma; Glutamic Acid; Guanidines; Intravitreal Injections; Male; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Retina; Retinal Diseases; Retinal Ganglion Cells; Retinal Neurons; Retinal Vessels; Serine Proteinase Inhibitors; Severity of Illness Index; Vascular Diseases | 2012 |
Baseline characteristics of the transient pattern electroretinogram in non-human primates: inter-ocular and inter-session variability.
Topics: Animals; Electroretinography; Female; Glaucoma; Macaca mulatta; N-Methylaspartate; Pattern Recognition, Visual; Photic Stimulation; Reproducibility of Results; Tetrodotoxin | 2003 |
Functional assessment of glutamate clearance mechanisms in a chronic rat glaucoma model using retinal ganglion cell calcium imaging.
Topics: Animals; Animals, Newborn; Aspartic Acid; Calcium; Cells, Cultured; Diagnostic Imaging; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; Glaucoma; Glutamic Acid; In Vitro Techniques; Intraocular Pressure; Male; N-Methylaspartate; Optic Nerve; Rats; Rats, Long-Evans; Retina; Retinal Ganglion Cells; Time Factors | 2005 |
Multifocal pattern electroretinogram: cellular origins and clinical implications.
Topics: Adult; Aged; Aged, 80 and over; Animals; Electroretinography; Evoked Potentials, Visual; Excitatory Amino Acid Agonists; Female; Glaucoma; Humans; Male; Middle Aged; N-Methylaspartate; Photic Stimulation; Retinal Ganglion Cells; Tetrodotoxin; Visual Fields | 2006 |
Apoptotic retinal ganglion cell death in the DBA/2 mouse model of glaucoma.
Topics: Aging; Animals; Annexin A5; Disease Models, Animal; Female; Glaucoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; N-Methylaspartate; Retinal Ganglion Cells; Species Specificity | 2007 |
Aloe-emodin metabolites protected N-methyl-d-aspartate-treated retinal ganglion cells by Cu-Zn superoxide dismutase.
Topics: Animals; Anthraquinones; Apoptosis; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Emodin; Enzyme Inhibitors; Gene Expression Regulation; Glaucoma; Glucuronides; Glutamic Acid; N-Methylaspartate; Neuroprotective Agents; Polymerase Chain Reaction; Protein Processing, Post-Translational; Rats; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; RNA, Messenger; Spectrometry, Mass, Electrospray Ionization; Sulfates; Superoxide Dismutase; Transcription, Genetic | 2007 |
Oscillatory potentials of the slow-sequence multifocal ERG in primates extracted using the Matching Pursuit method.
Topics: Animals; Disease Models, Animal; Electroretinography; gamma-Aminobutyric Acid; Glaucoma; Macaca; N-Methylaspartate; Photic Stimulation; Pipecolic Acids; Retina; Retinal Ganglion Cells; Signal Processing, Computer-Assisted; Tetrodotoxin | 2007 |
Effects of experimental glaucoma in macaques on the multifocal ERG. Multifocal ERG in laser-induced glaucoma.
Topics: Animals; Disease Models, Animal; Electroretinography; Glaucoma; Injections; Intraocular Pressure; Macaca mulatta; N-Methylaspartate; Retina; Tetrodotoxin; Visual Field Tests; Vitreous Body | 2000 |
Comparative effects of antiglaucoma drugs on voltage-dependent calcium channels.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Betaxolol; Calcium; Calcium Channels; Glaucoma; N-Methylaspartate; Radioligand Assay; Rats; Rats, Wistar; Retina | 2001 |