n-methylaspartate has been researched along with Encephalopathy, Toxic in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.22) | 18.2507 |
| 2000's | 21 (46.67) | 29.6817 |
| 2010's | 18 (40.00) | 24.3611 |
| 2020's | 5 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Chern, CJ; Chern, CR; Chodounská, H; Kudová, E; Lauková, M; Schonwald, A; Shakarjian, MP; Velíšek, L; Velíšková, J | 1 |
| Ma, J; Si, P; Sun, X; Wu, J; Yan, LJ; Yang, X; Yin, L; Zhang, C; Zhang, Y | 1 |
| Cheng, G; Gao, H; Jiang, X; Li, X; Liu, W; Ren, T; Shen, Z; Xu, Z; Yang, Y; Zhao, Q | 1 |
| Alberdi, E; Luchena, C; Matute, C; Ortiz-Sanz, C; Ruiz, A; Zuazo, J | 1 |
| Baril, N; Brezun, JM; Chaillan, FA; Cholvin, T; Giorgi, L; Poucet, B | 1 |
| Belfiore, M; Cariati, I; D'Arcangelo, G; Diociaiuti, M; Fioravanti, R; Frank, C; Gaddini, L; Macchia, G; Matteucci, A; Tancredi, V | 1 |
| Al-Baggou, BK; Salih, NA | 1 |
| Chen, L; Han, S; Li, J; Luo, Y; Wang, Y; Yin, Y; Zhao, L | 1 |
| Abdelsaid, MA; Baldowski, BR; Bollinger, KE; El-Azab, MF; El-Remessy, AB; Matragoon, S; Mohamed, IN; Mysona, BA; Saul, A; Shanab, AY | 1 |
| An, Y; Belevych, N; Chen, Q; Herschman, H; Quan, N; Wang, Y; Zhang, H | 1 |
| Ishii, K; Kuroki, T; Mori, A; Nakahara, T; Sakamoto, K | 1 |
| Asano, D; Ishii, K; Mori, A; Nakahara, T; Sakamoto, K | 1 |
| da Costa, FL; de Oliveira, AC; Gomez, MV; Gomez, RS; Lima, IV; Mendes-Goulart, VA; Pinto, MC; Resende, RR; Romano-Silva, MA; Rosa, DV | 1 |
| Cheng, B; Huang, Y; Li, D; Liu, G; Shen, W; Su, J; Zhang, YX; Zhou, WX | 1 |
| Harai, T; Hashimoto, K; Inoue, R; Mori, H | 1 |
| Carpenter, DM; Fong, SG; Hof, PR; Murray, EA; Rapp, PR; Shamy, JL; Tang, CY | 1 |
| Chang-Mu, C; Jen-Kun, L; Shing-Hwa, L; Shoei-Yn, LS | 1 |
| Huang, Z; Li, ZY; Mao, QQ; Zhong, XM | 1 |
| Hayes, RL; Kobeissy, F; Liu, MC; Wang, KK; Zhang, Z; Zheng, W | 1 |
| Muller, Gdo A; Severino, PC; Tasca, CI; Vandresen-Filho, S | 1 |
| Chan, MH; Chen, HH; Lin, YR | 1 |
| Acarin, L; Castellano, B; Gonzalez, B; Gonzalez, P; Peluffo, H; Villaverde, A | 1 |
| Blanc, T; Dahmani, S; Jegou-Colleter, S; Laudenbach, V; Marret, S; Tourrel, F | 1 |
| Chudasama, Y; Macgregor, EM; Prasad, JA | 1 |
| Isenoumi, K; Kitaoka, Y; Kobayashi, S; Kumai, T; Motoki, M; Ueno, S | 1 |
| Dikranian, K; Farber, NB; Jiang, X; Nemmers, B | 1 |
| Low, SJ; Roland, CL | 1 |
| Bachoo, R; Choi, YS; Gwag, BJ; Hong, SB; Jeon, HK; Jo, SY; Kang, HJ; Kim, EJ; Kim, KW; Kim, TK; Lee, HW; Reynolds, IJ; Won, SJ; Woo, RS | 1 |
| Antonelli, T; De Mattei, M; Ferraro, L; Finetti, S; Fournier, J; Fuxe, K; Tanganelli, S; Tomasini, MC | 1 |
| De Berardinis, MA; Domenici, MR; Frank, C; Grieco, R; Martire, A; Massotti, M; Minghetti, L; Nazzicone, V; Pepponi, R; Pèzzola, A; Pintor, A; Popoli, P; Potenza, RL; Reggio, R; Tebano, MT | 1 |
| Boeck, CR; Ganzella, M; Lottermann, A; Vendite, D | 1 |
| Aguirre, N; Goñi-Allo, B; Jordán, J; Ramos, M | 1 |
| Ali, C; Benchenane, K; Berezowski, V; Brillault, J; Bu, G; Cecchelli, R; Chuquet, J; Fernández-Monreal, M; López-Atalaya, JP; MacKenzie, ET; Nouvelot, A; Touzani, O; Vivien, D | 1 |
| Bakuridze, K; Düzenli, S; Gepdiremen, A | 1 |
| Hayashi, Y; Isenoumi, K; Kitaoka, Y; Kobayashi, S; Kogo, J; Kumai, T; Kuribayashi, K; Motoki, M; Munemasa, Y; Ueno, S | 1 |
| Ahmad, AS; Doré, S; Zhuang, H | 1 |
| Brunette, E; Hewitt, M; Kiedrowski, L; Lortie, K; Morley, P; Tauskela, JS | 1 |
| Fang, T; Hayes, RL; Kobeissy, FH; Ottens, AK; Sadasivan, S; Wang, KK; Zhang, Z | 1 |
| Choi, D; Harris, RH; Kohn, H; Kupferberg, HJ; Stables, JP; Stöhr, T; Walton, N; White, HS | 1 |
| Acarin, L; Arís, A; Castellano, B; González, B; González, P; Peluffo, H; Saura, J; Villaverde, A | 1 |
| Anrather, J; Avvedimento, EV; Cicale, M; Cuda, G; Iadecola, C; Paternò, R; Postiglione, A; Ruocco, A; Santillo, M; Serù, R | 1 |
| Berger, SP; Brudney, EG; Johnson, SW; Meshul, CK; Paquette, MA; Putterman, DB | 1 |
| Blumbergs, P; Cai, Z; Casson, RJ; Chotaliya, HP; Saggu, SK | 1 |
| Glowinski, J; Israël, M; Marin, P; Maus, M; Prémont, J | 1 |
| Morrisett, RA; Thomas, MP | 1 |
3 review(s) available for n-methylaspartate and Encephalopathy, Toxic
| Article | Year |
|---|---|
Cell signaling in NMDA preconditioning and neuroprotection in convulsions induced by quinolinic acid.
Topics: Animals; Brain; Brain Chemistry; Cerebrovascular Circulation; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Ischemic Preconditioning; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Seizures; Signal Transduction | 2011 |
[Neurological consequences after long-term sedation in the ICU].
Topics: Aging; Anesthetics, General; Animals; Cesarean Section; Conscious Sedation; Critical Care; Excitatory Amino Acid Agonists; Female; Fetal Alcohol Spectrum Disorders; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Premature; Intensive Care Units; N-Methylaspartate; Nervous System Diseases; Neurotoxicity Syndromes; Pregnancy; Primates; Synaptic Transmission; Teratogens | 2012 |
Review of NMDA antagonist-induced neurotoxicity and implications for clinical development.
Topics: Animals; Decision Making, Computer-Assisted; Female; Forecasting; Humans; Models, Biological; N-Methylaspartate; Neurotoxicity Syndromes; Receptors, N-Methyl-D-Aspartate | 2004 |
42 other study(ies) available for n-methylaspartate and Encephalopathy, Toxic
| Article | Year |
|---|---|
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnanolone; Pyrrolidonecarboxylic Acid; Rodentia; Spasm; Spasms, Infantile | 2023 |
Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity.
Topics: Calcium; Calcium Signaling; Cell Death; Cell Line, Tumor; Down-Regulation; ELAV-Like Protein 1; Excitatory Amino Acid Agonists; Humans; N-Methylaspartate; Neurons; Neurotoxicity Syndromes; Phosphorylation; Protein Kinase C; RNA Stability; RNA, Messenger; Serine; Sirtuin 1 | 2020 |
DCMQA, a caffeoylquinic acid derivative alleviates NMDA-induced neurotoxicity via modulating GluN2A and GluN2B-containing NMDA receptors in vitro.
Topics: Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Humans; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Quinic Acid; Receptors, N-Methyl-D-Aspartate | 2020 |
Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response.
Topics: Animals; Calcium; Cells, Cultured; Cytoprotection; Embryo, Mammalian; Endoplasmic Reticulum Stress; Guanabenz; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Physiological | 2020 |
Using MRI to predict the fate of excitotoxic lesions in rats.
Topics: Animals; Cerebellum; Cognition; Magnetic Resonance Imaging; Male; N-Methylaspartate; Neurotoxicity Syndromes; Rats; Rats, Long-Evans | 2018 |
Calcitonin native prefibrillar oligomers but not monomers induce membrane damage that triggers NMDA-mediated Ca
Topics: Amyloid; Animals; Calcitonin; Calcium; Calcium Signaling; Cell Line; Cell Membrane; Fish Proteins; Long-Term Potentiation; Mice; N-Methylaspartate; Neurons; Neurotoxicity Syndromes; Protein Multimerization; Salmon | 2019 |
Effect of memantine hydrochloride on cisplatin-induced neurobehavioral toxicity in mice.
Topics: Animals; Antineoplastic Agents; Behavior, Animal; Cisplatin; Disease Models, Animal; Excitatory Amino Acid Antagonists; Male; Memantine; Mice, Inbred BALB C; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Psychomotor Performance | 2020 |
Tat-collapsin response mediator protein 2 (CRMP2) increases the survival of neurons after NMDA excitotoxity by reducing the cleavage of CRMP2.
Topics: Animals; Cells, Cultured; Gene Products, tat; Intercellular Signaling Peptides and Proteins; Mice; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phosphorylation; Rats; Transfection | 2013 |
Deletion of thioredoxin-interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury.
Topics: Adult; Aged; Animals; Apoptosis; Carrier Proteins; Cells, Cultured; Ependymoglial Cells; Female; Glaucoma, Open-Angle; Humans; Inflammation; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; N-Methylaspartate; Neurotoxicity Syndromes; Retina; Thioredoxin-Disulfide Reductase; Thioredoxins; Tumor Necrosis Factor-alpha; Tyrosine; Vascular System Injuries | 2014 |
Neuronal and nonneuronal COX-2 expression confers neurotoxic and neuroprotective phenotypes in response to excitotoxin challenge.
Topics: Analysis of Variance; Animals; Antigens, Differentiation; Cyclooxygenase 2; Disease Models, Animal; Gene Expression Regulation; Glycine; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Phosphopyruvate Hydratase; Tetrazoles | 2014 |
Histological protection by nilvadipine against neurotoxicity induced by NOC12, a nitric oxide donor, in the rat retina.
Topics: Animals; Antioxidants; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Nifedipine; Nitric Oxide Donors; Nitroso Compounds; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retina; Retinal Diseases | 2014 |
Regression of retinal capillaries following N-methyl-D-aspartate-induced neurotoxicity in the neonatal rat retina.
Topics: Age Factors; Animals; Animals, Newborn; Capillaries; Collagen Type IV; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression Regulation, Developmental; Male; N-Methylaspartate; Neurotoxicity Syndromes; Phenylurea Compounds; Plant Lectins; Quinazolines; Rats; Rats, Sprague-Dawley; Rec A Recombinases; Retinal Degeneration; Statistics, Nonparametric; Vascular Endothelial Growth Factor A | 2015 |
Glycine transporters type 1 inhibitor promotes brain preconditioning against NMDA-induced excitotoxicity.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Agonists; Fluoresceins; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neurotoxicity Syndromes; Sarcosine; Time Factors; Tritium | 2015 |
Modulating the Balance of Synaptic and Extrasynaptic NMDA Receptors Shows Positive Effects against Amyloid-β-Induced Neurotoxicity.
Topics: Amyloid beta-Peptides; Animals; Antimetabolites; Cycloserine; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; Locomotion; Male; Maze Learning; N-Methylaspartate; Nesting Behavior; Neurotoxicity Syndromes; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Signal Transduction; Synapses | 2017 |
NMDA- and beta-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice.
Topics: Amyloid beta-Peptides; Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurotoxicity Syndromes; Neurotoxins; Peptide Fragments; Racemases and Epimerases; Serine | 2008 |
Alterations of white matter tracts following neurotoxic hippocampal lesions in macaque monkeys: a diffusion tensor imaging study.
Topics: Animals; Anisotropy; Brain Mapping; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Macaca mulatta; Male; N-Methylaspartate; Nerve Fibers, Myelinated; Neurotoxicity Syndromes | 2010 |
Characterization of neurotoxic effects of NMDA and the novel neuroprotection by phytopolyphenols in mice.
Topics: Analysis of Variance; Animals; Biphenyl Compounds; Ca(2+) Mg(2+)-ATPase; Calcium; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Agonists; Flavonoids; Lignans; Linear Models; Male; Membrane Potential, Mitochondrial; Mice; Motor Activity; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phenols; Phytotherapy; Polyphenols; Psychomotor Performance; Reactive Oxygen Species; Rotarod Performance Test; Silver Staining; Sodium-Potassium-Exchanging ATPase; Synaptosomes | 2010 |
Paeoniflorin protects against NMDA-induced neurotoxicity in PC12 cells via Ca2+ antagonism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Bridged-Ring Compounds; Calbindin 1; Calbindins; Calcium; Cell Death; Cell Survival; Glucosides; Humans; L-Lactate Dehydrogenase; Monoterpenes; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Rats; S100 Calcium Binding Protein G | 2011 |
Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain; Brain Injuries; Calpain; Caspase 3; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Gene Expression Regulation; Male; Molecular Weight; N-Methylaspartate; Nerve Degeneration; Neurons; Neurotoxicity Syndromes; Neurotoxins; Peptide Hydrolases; Protein Isoforms; Rats; tau Proteins | 2011 |
Toluene exposure during brain growth spurt and adolescence produces differential effects on N-methyl-D-aspartate receptor-mediated currents in rat hippocampus.
Topics: Aging; Animals; CA1 Region, Hippocampal; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhalant Abuse; Injections, Intraperitoneal; Male; N-Methylaspartate; Nerve Tissue Proteins; Neural Conduction; Neurons; Neurotoxicity Syndromes; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solvents; Toluene | 2011 |
Interleukin-10 overexpression does not synergize with the neuroprotective action of RGD-containing vectors after postnatal brain excitotoxicity but modulates the main inflammatory cell responses.
Topics: Analysis of Variance; Animals; Animals, Newborn; CD11b Antigen; Cell Death; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fluoresceins; Gene Expression Regulation; Genetic Vectors; Glial Fibrillary Acidic Protein; Histidine; Interleukin-10; Macrophages; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; Neurotoxicity Syndromes; Neutrophils; Oligopeptides; Organic Chemicals; Peroxidase; Plant Lectins; Rats; Rats, Long-Evans; Transduction, Genetic; Vimentin | 2012 |
Lesions of the thalamic reuniens cause impulsive but not compulsive responses.
Topics: Animals; Attention; Behavior, Animal; Choice Behavior; Compulsive Behavior; Disease Models, Animal; Habituation, Psychophysiologic; Impulsive Behavior; Inhibition, Psychological; Male; Midline Thalamic Nuclei; Motivation; Motor Activity; N-Methylaspartate; Neurotoxicity Syndromes; Rats; Rats, Long-Evans; Reaction Time; Reward; Time Factors | 2013 |
Neuroprotective effect of nitric oxide against NMDA-induced neurotoxicity in the rat retina is associated with tyrosine hydroxylase expression.
Topics: Animals; Benzazepines; Blotting, Western; Cell Count; Chromatography, High Pressure Liquid; Domperidone; Dopamine; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Agonists; Free Radical Scavengers; Gene Expression Regulation; Male; N-Methylaspartate; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Rats, Wistar; Retina; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tyrosine 3-Monooxygenase | 2003 |
Muscimol prevents NMDA antagonist neurotoxicity by activating GABAA receptors in several brain regions.
Topics: Animals; Cell Count; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Functional Laterality; GABA Agonists; Muscimol; N-Methylaspartate; Nerve Degeneration; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Septal Nuclei; Stereotaxic Techniques; Thalamus | 2003 |
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.
Topics: Animals; Brain Injury, Chronic; Brain Ischemia; Calcium; Cells, Cultured; Coculture Techniques; Disease Models, Animal; DNA-Binding Proteins; Excitatory Amino Acid Agonists; Fluorescent Dyes; Gene Expression Regulation; Hypoxia-Ischemia, Brain; Membrane Potentials; Mice; Mice, Transgenic; Mitochondria; N-Methylaspartate; Neuroglia; Neurons; Neurotoxicity Syndromes; Neurotoxins; RNA, Messenger; Telomerase | 2004 |
Neurotensin enhances endogenous extracellular glutamate levels in primary cultures of rat cortical neurons: involvement of neurotensin receptor in NMDA induced excitotoxicity.
Topics: Animals; Bisbenzimidazole; Calcium; Cells, Cultured; Cerebral Cortex; Chromatin; Coloring Agents; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; N-Methylaspartate; Naphthalenes; Neurons; Neurotensin; Neurotoxicity Syndromes; Peptide Fragments; Pyrazoles; Quinolines; Rats; Receptors, Neurotensin | 2004 |
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.
Topics: Animals; Body Weight; Calcium; Cells, Cultured; Electroencephalography; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Male; Maze Learning; Microdialysis; N-Methylaspartate; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Pyridines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2004 |
NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice.
Topics: Animals; Apoptosis; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Humans; Male; Mice; Motor Activity; N-Methylaspartate; Neurons; Neurotoxicity Syndromes; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Seizures | 2004 |
In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-d-aspartate.
Topics: Animals; Dizocilpine Maleate; Drug Administration Routes; Drug Administration Schedule; Male; Malonates; Minocycline; N-Methylaspartate; Neostriatum; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Rats; Rats, Wistar; Treatment Outcome | 2005 |
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis.
Topics: Animals; Blood-Brain Barrier; Brain; Cold Temperature; Low Density Lipoprotein Receptor-Related Protein-1; Male; N-Methylaspartate; Neurotoxicity Syndromes; Plasminogen Activator Inhibitor 1; Protein Transport; Rats; Rats, Sprague-Dawley; Tissue Plasminogen Activator | 2005 |
The effects of ruthenium red, dantrolene and nimodipine, alone or in combination, in NMDA induced neurotoxicity of cerebellar granular cell culture of rats.
Topics: Animals; Calcium; Cells, Cultured; Cerebellum; Dantrolene; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; Nimodipine; Rats; Rats, Sprague-Dawley; Ruthenium Red | 2005 |
Neuroprotective effect of atrial natriuretic peptide against NMDA-induced neurotoxicity in the rat retina.
Topics: Analysis of Variance; Animals; Antibodies; Atrial Natriuretic Factor; Benzazepines; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Domperidone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Excitatory Amino Acid Agonists; Immunohistochemistry; Intracellular Space; Male; N-Methylaspartate; Neuroprotective Agents; Neurotoxicity Syndromes; PC12 Cells; Rats; Rats, Wistar; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine 3-Monooxygenase | 2006 |
Heme oxygenase-1 protects brain from acute excitotoxicity.
Topics: Animals; Animals, Newborn; Brain; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Heme Oxygenase-1; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Neurotoxicity Syndromes; Receptors, N-Methyl-D-Aspartate | 2006 |
Unconventional neuroprotection against Ca2+ -dependent insults by metalloporphyrin catalytic antioxidants.
Topics: Animals; Antioxidants; Brain Ischemia; Calcium; Calcium Signaling; Catalysis; Cell Membrane; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Fluoresceins; Glutamic Acid; Metalloporphyrins; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Reactive Oxygen Species; Sodium-Calcium Exchanger; TRPM Cation Channels | 2006 |
Calpain-mediated collapsin response mediator protein-1, -2, and -4 proteolysis after neurotoxic and traumatic brain injury.
Topics: Adaptor Proteins, Signal Transducing; Animals; Brain; Brain Injuries; Calpain; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Excitatory Amino Acid Agonists; Hippocampus; Immunoblotting; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; L-Lactate Dehydrogenase; Marine Toxins; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Oxocins; Phosphoproteins; Rats; Rats, Sprague-Dawley | 2007 |
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy.
Topics: Acetamides; Animals; Anticonvulsants; Bicuculline; Cobalt; Convulsants; Electroshock; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Reflex; Excitatory Amino Acid Agonists; GABA Antagonists; Homocysteine; Kindling, Neurologic; Lacosamide; Male; Mice; N-Methylaspartate; Neurotoxicity Syndromes; Pentylenetetrazole; Picrotoxin; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2007 |
RGD domains neuroprotect the immature brain by a glial-dependent mechanism.
Topics: Animals; Astrocytes; Behavior, Animal; Brain; Brain Chemistry; Cell Count; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Data Interpretation, Statistical; Densitometry; Excitatory Amino Acids; Female; Immunohistochemistry; Microglia; N-Methylaspartate; Nerve Degeneration; Neuroglia; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Neutrophil Infiltration; Oligopeptides; Pregnancy; Rats; Rats, Long-Evans | 2007 |
Farnesyl transferase inhibitors induce neuroprotection by inhibiting Ha-Ras signalling pathway.
Topics: Animals; Brain; Cell Survival; Cells, Cultured; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Agonists; Farnesyltranstransferase; Male; Maleates; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Tetrazolium Salts; Thiazoles | 2007 |
Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias.
Topics: Adrenergic Agents; Amphetamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Dextromethorphan; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Ligands; Male; N-Methylaspartate; Neurotoxicity Syndromes; Oxidopamine; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
The spatiotemporal pattern of somal and axonal pathology after perikaryal excitotoxic injury to retinal ganglion cells: a histological and morphometric study.
Topics: Analysis of Variance; Animals; Axons; Cell Count; Disease Models, Animal; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neurotoxicity Syndromes; Optic Nerve; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Time Factors | 2008 |
Pyruvate and lactate protect striatal neurons against N-methyl-D-aspartate-induced neurotoxicity.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cytosol; Energy Metabolism; Excitatory Amino Acid Agonists; Free Radical Scavengers; Glucose; Glutamic Acid; Glycolysis; Kinetics; Lactic Acid; Mice; Mitochondria; N-Methylaspartate; Neostriatum; Neurons; Neurotoxicity Syndromes; Oxygen Consumption; Pyruvic Acid | 1999 |
Dynamics of NMDAR-mediated neurotoxicity during chronic ethanol exposure and withdrawal.
Topics: Alcoholism; Animals; Biological Transport; Drug Interactions; Ethanol; Female; Intercalating Agents; Male; N-Methylaspartate; Neurotoxicity Syndromes; Propidium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Substance Withdrawal Syndrome | 2000 |