Page last updated: 2024-08-22

n-methylaspartate and Dyskinesia, Drug-Induced

n-methylaspartate has been researched along with Dyskinesia, Drug-Induced in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (40.00)18.2507
2000's5 (33.33)29.6817
2010's2 (13.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Frouni, I; Huot, P1
Liu, M; Tuo, J; Xu, Z; Yu, C; Zhang, F; Zhang, J; Zhang, L1
Di Rocco, A; Howard, J; Varanese, S1
Bagetta, V; Bonito-Oliva, A; Calabresi, P; Carta, M; Di Luca, M; Errico, F; Fisone, G; Gardoni, F; Marinucci, S; Napolitano, F; Picconi, B; Romano, R; Usiello, A; Vitucci, D; Zianni, E1
Chase, TN; Farmer, C; Gillespie, M; Morris, MJ; Mosby, K; Verhagen Metman, L; Wuu, J1
Jankovic, J; Olanow, CW1
Berger, SP; Brudney, EG; Johnson, SW; Meshul, CK; Paquette, MA; Putterman, DB1
Bartsch, R; Engel, J; Hönack, D; Kutscher, B; Löscher, W; Polymeropoulos, EE; Rostock, A; Rundfeldt, C; Tober, C; White, HS; Wolf, HH1
Grimm, JW; Kruzich, PJ; See, RE1
Blanchet, PJ; Chase, TN; Del Dotto, P; Natté, R; van den Munckhof, P; Verhagen Metman, L1
Arts, M; Bemelmans, F; Cools, A1
Klockgether, T; Löschmann, PA; Spieker, S1
Emre, M; Hanağasi, HA; Kaptanoglu, G; Sahin, HA1
Kulkarni, SK; Naidu, PS1
Kannari, K; Markstein, R1

Reviews

3 review(s) available for n-methylaspartate and Dyskinesia, Drug-Induced

ArticleYear
Glutamate modulation for the treatment of levodopa induced dyskinesia: a brief review of the drugs tested in the clinic.
    Neurodegenerative disease management, 2022, Volume: 12, Issue:4

    Topics: Antiparkinson Agents; Dyskinesia, Drug-Induced; Glutamic Acid; Humans; Levodopa; N-Methylaspartate; Parkinson Disease

2022
Levodopa-induced dyskinesia: interplay between the N-methyl-D-aspartic acid receptor and neuroinflammation.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Aged; Dyskinesia, Drug-Induced; Glutamic Acid; Humans; Levodopa; Middle Aged; N-Methylaspartate; Neuroinflammatory Diseases; Parkinson Disease; Quality of Life; Receptors, N-Methyl-D-Aspartate

2023
Neuroprotective therapy in Parkinson's disease and motor complications: a search for a pathogenesis-targeted, disease-modifying strategy.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20 Suppl 11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiparkinson Agents; Coenzymes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Humans; Indans; Levodopa; Membrane Proteins; N-Methylaspartate; Neuroprotective Agents; Parkinson Disease; Prostaglandin-Endoperoxide Synthases; Ubiquinone; Vitamin E

2005

Trials

3 trial(s) available for n-methylaspartate and Dyskinesia, Drug-Induced

ArticleYear
Huntington's disease: a randomized, controlled trial using the NMDA-antagonist amantadine.
    Neurology, 2002, Sep-10, Volume: 59, Issue:5

    Topics: Adult; Aged; Amantadine; Chorea; Cognition; Cross-Over Studies; Dopamine Agents; Double-Blind Method; Dyskinesia, Drug-Induced; Female; Humans; Huntington Disease; Male; Middle Aged; N-Methylaspartate; Treatment Outcome

2002
A trial of dextromethorphan in parkinsonian patients with motor response complications.
    Movement disorders : official journal of the Movement Disorder Society, 1998, Volume: 13, Issue:3

    Topics: Activities of Daily Living; Aged; Antiparkinson Agents; Carbidopa; Cross-Over Studies; Dextromethorphan; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Motor Skills; N-Methylaspartate; Neurologic Examination; Parkinson Disease

1998
The NMDA antagonist budipine can alleviate levodopa-induced motor fluctuations.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:3

    Topics: Adult; Aged; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Middle Aged; N-Methylaspartate; Parkinson Disease; Pilot Projects; Piperidines; Severity of Illness Index

1999

Other Studies

9 other study(ies) available for n-methylaspartate and Dyskinesia, Drug-Induced

ArticleYear
NMDA antagonist memantine improves levodopa-induced dyskinesias and "on-off" phenomena in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Mar-15, Volume: 25, Issue:4

    Topics: Aged; Antiparkinson Agents; Dopamine Agents; Dyskinesia, Drug-Induced; Female; Humans; Incidence; Levodopa; Male; Memantine; N-Methylaspartate; Parkinson Disease

2010
Higher free D-aspartate and N-methyl-D-aspartate levels prevent striatal depotentiation and anticipate L-DOPA-induced dyskinesia.
    Experimental neurology, 2011, Volume: 232, Issue:2

    Topics: Action Potentials; Animals; Antiparkinson Agents; Corpus Striatum; D-Aspartate Oxidase; D-Aspartic Acid; Dyskinesia, Drug-Induced; Extracellular Signal-Regulated MAP Kinases; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neuronal Plasticity; Oxidopamine; Parkinsonian Disorders; Phosphorylation; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sympatholytics; Synapses

2011
Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias.
    Neuroreport, 2008, Jan-08, Volume: 19, Issue:1

    Topics: Adrenergic Agents; Amphetamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Dextromethorphan; Disease Models, Animal; Dopamine Agents; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Levodopa; Ligands; Male; N-Methylaspartate; Neurotoxicity Syndromes; Oxidopamine; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors

2008
D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.
    Epilepsy research, 1996, Volume: 23, Issue:3

    Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Bicuculline; Carbamates; Dyskinesia, Drug-Induced; Electroshock; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Pentylenetetrazole; Phenylenediamines; Postural Balance; Rats; Rats, Wistar; Seizures; Strychnine

1996
Emergence of oral and locomotor activity in chronic haloperidol-treated rats following cortical N-methyl-D-aspartate stimulation.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dyskinesia, Drug-Induced; Female; Haloperidol; Motor Activity; Motor Cortex; Mouth; Movement; N-Methylaspartate; Rats; Rats, Sprague-Dawley

1998
Activation of N-methyl-D-aspartate receptors in the feline retrorubral nucleus elicits orofacial dyskinesia.
    European journal of pharmacology, 1998, May-15, Volume: 349, Issue:1

    Topics: Animals; Catecholamines; Cats; Caudate Nucleus; Dopamine Agonists; Dyskinesia, Drug-Induced; Ear; Excitatory Amino Acid Agonists; Imidazolines; Male; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Red Nucleus; Tongue

1998
The use of NMDA antagonist memantine in drug-resistant dyskinesias resulting from L-dopa.
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5

    Topics: Adult; Antiparkinson Agents; Dopamine Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Humans; Levodopa; Male; Memantine; N-Methylaspartate; Parkinsonian Disorders; Treatment Outcome

2000
Excitatory mechanisms in neuroleptic-induced vacuous chewing movements (VCMs): possible involvement of calcium and nitric oxide.
    Behavioural pharmacology, 2001, Volume: 12, Issue:3

    Topics: Animals; Antipsychotic Agents; Calcium; Dyskinesia, Drug-Induced; Glutamic Acid; Haloperidol; Male; Mastication; N-Methylaspartate; Nitric Oxide; Rats; Rats, Wistar; Stereotyped Behavior

2001
Dopamine agonists potentiate antiakinetic effects of competitive NMDA-antagonists in monoamine-depleted mice.
    Journal of neural transmission. General section, 1991, Volume: 84, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; alpha-Methyltyrosine; Animals; Binding, Competitive; Caudate Nucleus; Dopamine Agents; Drug Synergism; Dyskinesia, Drug-Induced; Indoles; Male; Methyltyrosines; Mice; Motor Activity; N-Methylaspartate; Piperazines; Putamen; Receptors, Dopamine; Receptors, N-Methyl-D-Aspartate; Reserpine

1991