Page last updated: 2024-08-22

n-methylaspartate and Disease Exacerbation

n-methylaspartate has been researched along with Disease Exacerbation in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (58.33)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishii, K; Kurauchi, Y; Mori, A; Nakahara, T; Sakamoto, K1
Cunningham, CJ; Liu, X; Patel, KP; Sharma, NM; Zheng, H1
André, VM; Deng, Y; Figueroa, BE; Friedlander, R; Graham, RK; Hayden, MR; Joshi, P; Leavitt, BR; Levine, MS; Lu, G; Metzler, M; Pouladi, MA; Raymond, L; Slow, EJ; Wu, NP1
Fu, R; Heckman, CJ; Jiang, M; Schuster, JE; Siddique, T1
Bissada, N; Carroll, J; Cowan, C; Deng, Y; Faull, RL; Graham, RK; Gray, M; Hayden, MR; Metzler, M; Pouladi, MA; Raymond, LA; Vaid, K; Wang, L; Yang, XW1
Hangai, M; Ikeda, HO; Kakizuka, A; Muraoka, Y; Nakano, N; Toda, Y; Yoshimura, N1
Alaghband, Y; Ando, TK; André, VM; Cepeda, C; Cummings, DM; Hickey, MA; Hong, SC; Joshi, PR; Levine, MS; Watson, JB; Zhu, C1
Doody, R; Ferris, S; Möbius, HJ; Reisberg, B; Schmitt, F; Stöffler, A1
Souder, E1
Cotter, VT1
Drozda, M; Ferrante, RJ; Friedlander, RM; Gullans, S; Hartley, DM; Kim, BY; Kristal, BS; Li, M; Liu, AS; Ona, V; Przedborski, S; Sarang, S; Stavrovskaya, IG; Wu, DC; Zhu, S1
Forette, F; Möbius, HJ; Orgogozo, JM; Rigaud, AS; Stöffler, A1

Reviews

3 review(s) available for n-methylaspartate and Disease Exacerbation

ArticleYear
Neurovascular interactions in the retina: physiological and pathological roles.
    Journal of pharmacological sciences, 2013, Volume: 123, Issue:2

    Topics: Angiotensin II; Catecholamines; Cell Communication; Diabetic Retinopathy; Disease Progression; Drug Discovery; Endothelin Receptor Antagonists; Endothelin-1; Glaucoma; Homeostasis; Molecular Targeted Therapy; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Potassium Channels, Calcium-Activated; Receptors, GABA; Retina; Retinal Diseases; Retinal Vessels

2013
Neuropathology in Alzheimer's disease: target of pharmacotherapy.
    Journal of the American Academy of Nurse Practitioners, 2005, Volume: Suppl

    Topics: Acetylcholine; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholinesterase Inhibitors; Disease Progression; Estrogens; Glutamic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; N-Methylaspartate; Neurofibrillary Tangles; Neuropharmacology; Neurotransmitter Agents

2005
Alzheimer's disease: issues and challenges in primary care.
    The Nursing clinics of North America, 2006, Volume: 41, Issue:1

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Caregivers; Cholinesterase Inhibitors; Disease Progression; Family; Geriatric Assessment; Geriatric Nursing; Humans; Mass Screening; N-Methylaspartate; Neuropsychological Tests; Nurse's Role; Nursing Assessment; Office Visits; Patient Education as Topic; Primary Health Care; Psychiatric Status Rating Scales; Quality of Life; Self Efficacy; Severity of Illness Index; United States

2006

Trials

2 trial(s) available for n-methylaspartate and Disease Exacerbation

ArticleYear
Memantine in moderate-to-severe Alzheimer's disease.
    The New England journal of medicine, 2003, Apr-03, Volume: 348, Issue:14

    Topics: Activities of Daily Living; Aged; Alzheimer Disease; Behavior; Cognition; Disease Progression; Excitatory Amino Acid Antagonists; Female; Humans; Male; Memantine; Middle Aged; N-Methylaspartate; Severity of Illness Index

2003
Efficacy and safety of memantine in patients with mild to moderate vascular dementia: a randomized, placebo-controlled trial (MMM 300).
    Stroke, 2002, Volume: 33, Issue:7

    Topics: Aged; Cognition; Dementia, Vascular; Disease Progression; Dizziness; Dopamine Agents; Double-Blind Method; Female; France; Humans; Male; Memantine; Middle Aged; N-Methylaspartate; Neuropsychological Tests; Treatment Outcome

2002

Other Studies

7 other study(ies) available for n-methylaspartate and Disease Exacerbation

ArticleYear
Hypoxia-Inducible Factor-1α Mediates Increased Sympathoexcitation via Glutamatergic N-Methyl-d-Aspartate Receptors in the Paraventricular Nucleus of Rats With Chronic Heart Failure.
    Circulation. Heart failure, 2016, Volume: 9, Issue:11

    Topics: Animals; Cell Line; Chromatin Immunoprecipitation; Chronic Disease; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agonists; Heart Failure; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; In Vitro Techniques; Male; N-Methylaspartate; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Sympathetic Nervous System; Up-Regulation

2016
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Feb-18, Volume: 29, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Disease Progression; Genetic Predisposition to Disease; Huntington Disease; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Degeneration; Neurotoxins; Organ Culture Techniques; Phenotype; Quinolinic Acid; Stress, Physiological; Synaptic Membranes; Synaptic Potentials; Synaptic Transmission

2009
Progressive changes in synaptic inputs to motoneurons in adult sacral spinal cord of a mouse model of amyotrophic lateral sclerosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Dec-02, Volume: 29, Issue:48

    Topics: Action Potentials; Age Factors; Amyotrophic Lateral Sclerosis; Animals; Biophysics; Chi-Square Distribution; Disease Models, Animal; Disease Progression; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Interneurons; Mice; Mice, Transgenic; Motor Neurons; Mutation; N-Methylaspartate; Patch-Clamp Techniques; Psychomotor Performance; Quinoxalines; Reaction Time; Reflex; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Synapses

2009
Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Nov-10, Volume: 30, Issue:45

    Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Caspase 6; Corpus Striatum; Disease Progression; Humans; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Mice; Mice, Transgenic; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins

2010
Longitudinal and simultaneous imaging of retinal ganglion cells and inner retinal layers in a mouse model of glaucoma induced by N-methyl-D-aspartate.
    Investigative ophthalmology & visual science, 2011, Nov-11, Volume: 52, Issue:12

    Topics: Amacrine Cells; Animals; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agonists; Glaucoma; Green Fluorescent Proteins; Longitudinal Studies; Male; Mice; Mice, Transgenic; N-Methylaspartate; Ophthalmoscopy; Optic Disk; Reproducibility of Results; Retinal Ganglion Cells; Tomography, Optical Coherence

2011
A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.
    Journal of neurophysiology, 2012, Volume: 107, Issue:2

    Topics: Analysis of Variance; Animals; Body Weight; Corpus Striatum; Disease Models, Animal; Disease Progression; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Genetic Predisposition to Disease; Genotype; Humans; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Muscle Strength; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Patch-Clamp Techniques; Phenotype; Rotarod Performance Test; Seizures; Trinucleotide Repeat Expansion

2012
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice.
    Nature, 2002, May-02, Volume: 417, Issue:6884

    Topics: Age of Onset; Amyotrophic Lateral Sclerosis; Animals; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Cytochrome c Group; Disease Progression; Enzyme Activation; Humans; Infarction, Middle Cerebral Artery; Ischemia; Mice; Mice, Inbred C57BL; Minocycline; Mitochondria; Mitochondrial Swelling; N-Methylaspartate; Permeability; Rats; Survival Rate; Tumor Cells, Cultured

2002