n-methylaspartate has been researched along with Depressive Disorder, Major in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatia, NY; Doshi, GM; Kale, PP; Ved, HS | 1 |
| Chae, WR; Deuter, CE; Kaczmarczyk, M; Nowacki, J; Otte, C; Piber, D; Wingenfeld, K | 1 |
| Cooper, T; Seigler, MD; Stahl, S | 1 |
| Gardier, AM; Guilloux, JP; Nguyen, TML | 1 |
| Chen, Y; Liang, J; Liu, X; Qu, C; Shi, S; Yang, B; Yang, H | 1 |
| Gilbert, JR; Nugent, AC; Wills, KE; Yarrington, JS; Zarate, CA | 1 |
| Farber, NB | 1 |
| Beck, J; Borgwardt, S; Deutschenbaur, L; Hasler, G; Kiyhankhadiv, A; Lang, UE; Mühlhauser, M; Sollberger, D; Walter, M | 1 |
| Lloyd, RL; Pekary, AE; Sattin, A | 1 |
| Eby, GA; Eby, KL | 1 |
| Ameli, R; Brutsche, NE; DiazGranados, N; Henter, ID; Ibrahim, LA; Luckenbaugh, DA; Machado-Vieira, R; Zarate, CA | 1 |
| Baumann, J; Diazgranados, N; Ibrahim, L; Luckenbaugh, DA; Machado-Vieira, R; Mallinger, AG; Zarate, CA | 1 |
| Brutsche, N; Duncan, WC; Sarasso, S; Selter, J; Zarate, CA | 1 |
| Bakish, D; Beaulieu, S; Young, LT | 1 |
| Magarinos, AM; McEwen, BS; Reagan, LP | 1 |
| Coyle, JT; Frye, MA; Huggins, T; Post, RM; Tsai, GE | 1 |
| Deakin, JF; Guimarães, FS; Oliveira, RM | 1 |
6 review(s) available for n-methylaspartate and Depressive Disorder, Major
| Article | Year |
|---|---|
Importance of Exploring N-Methyl-D-Aspartate (NMDA) as a Future Perspective Target in Depression.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate | 2022 |
[Ketamine: a neuropsychotropic drug with an innovative mechanism of action].
Topics: Animals; Antidepressive Agents; Depressive Disorder, Major; Glutamic Acid; Ketamine; N-Methylaspartate; Pharmaceutical Preparations; Receptors, AMPA | 2023 |
Role of calcium, glutamate and NMDA in major depression and therapeutic application.
Topics: Animals; Antidepressive Agents; Calcium; Depressive Disorder, Major; Glutamic Acid; Humans; N-Methylaspartate; Neurogenesis; Neuronal Plasticity; Neurotransmitter Agents | 2016 |
Magnesium for treatment-resistant depression: a review and hypothesis.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; D-Aspartic Acid; Depression; Depressive Disorder; Depressive Disorder, Major; Fast Foods; Humans; Imipramine; Magnesium; Magnesium Deficiency; Mental Disorders; Models, Neurological; N-Methylaspartate; Randomized Controlled Trials as Topic; Suicide, Attempted | 2010 |
The neurobiology of treatment response to antidepressants and mood stabilizing medications.
Topics: Adenylyl Cyclases; Antidepressive Agents; Brain; CREB-Binding Protein; Cyclic AMP; Depressive Disorder, Major; Humans; N-Methylaspartate; Nuclear Proteins; Trans-Activators | 2002 |
Structural plasticity and tianeptine: cellular and molecular targets.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents, Tricyclic; Apoptosis; Atrophy; Dentate Gyrus; Depressive Disorder, Major; Glutamic Acid; Hippocampus; Humans; N-Methylaspartate; Neuronal Plasticity; Neurons; Serotonin; Thiazepines | 2002 |
4 trial(s) available for n-methylaspartate and Depressive Disorder, Major
| Article | Year |
|---|---|
No influence of mineralocorticoid and glutamatergic NMDA receptor stimulation on spatial learning and memory in individuals with major depression.
Topics: Adult; Depression; Depressive Disorder, Major; Female; Hippocampus; Humans; Male; Maze Learning; Memory; Middle Aged; Mineralocorticoids; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spatial Learning; Spatial Memory; Young Adult | 2022 |
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling.
Topics: Adolescent; Adult; Affect; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infusions, Intravenous; Ketamine; Magnetoencephalography; Male; Middle Aged; Models, Neurological; N-Methylaspartate; Time Factors; Treatment Outcome; Young Adult | 2018 |
Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
Topics: Adult; Antidepressive Agents; Depression; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Antagonists; Female; Humans; Infusions, Intravenous; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Suicidal Ideation; Time Factors; Treatment Outcome | 2010 |
Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.
Topics: Adolescent; Adult; Affect; Aged; Antidepressive Agents; Biomarkers; Depressive Disorder, Major; Drug Resistance; Electroencephalography; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Sleep; Young Adult | 2013 |
7 other study(ies) available for n-methylaspartate and Depressive Disorder, Major
| Article | Year |
|---|---|
Rapid onset brain plasticity at novel pharmacologic targets hypothetically drives innovations for rapid onset antidepressant actions.
Topics: Antidepressive Agents; Depressive Disorder, Major; gamma-Aminobutyric Acid; Hallucinogens; Humans; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate | 2023 |
The activation of
Topics: Action Potentials; Animals; Calcium; Calcium Channels, L-Type; Depressive Disorder, Major; Disease Models, Animal; Dizocilpine Maleate; Heart Ventricles; Humans; Myocytes, Cardiac; N-Methylaspartate; Patch-Clamp Techniques; Potassium; Rats; Receptors, N-Methyl-D-Aspartate; Shal Potassium Channels | 2017 |
NMDA Antagonists for Treatment-Resistant Depression.
Topics: Depression; Depressive Disorder, Major; Humans; Ketamine; N-Methylaspartate; Pilot Projects | 2019 |
Ketamine modulates TRH and TRH-like peptide turnover in brain and peripheral tissues of male rats.
Topics: Animals; Brain; Depressive Disorder, Major; Humans; Ketamine; Male; N-Methylaspartate; Peptides; Rats; Rats, Sprague-Dawley; Suicide; Thyrotropin-Releasing Hormone | 2015 |
Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression.
Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Electroconvulsive Therapy; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intravenous; Ketamine; Linear Models; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Sample Size; Socioeconomic Factors; Treatment Failure; Young Adult | 2011 |
Low cerebrospinal fluid glutamate and glycine in refractory affective disorder.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Drug Resistance; Electroconvulsive Therapy; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; N-Methylaspartate; Statistics as Topic | 2007 |
Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders.
Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Hippocampus; Humans; Immunohistochemistry; Male; Middle Aged; N-Methylaspartate; Nitric Oxide Synthase Type I; Schizophrenia; Signal Transduction | 2008 |