Page last updated: 2024-08-22

n-methylaspartate and Depression, Involutional

n-methylaspartate has been researched along with Depression, Involutional in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's9 (52.94)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Bhatia, NY; Doshi, GM; Kale, PP; Ved, HS1
Chae, WR; Deuter, CE; Kaczmarczyk, M; Nowacki, J; Otte, C; Piber, D; Wingenfeld, K1
Cooper, T; Seigler, MD; Stahl, S1
Gardier, AM; Guilloux, JP; Nguyen, TML1
Chen, Y; Liang, J; Liu, X; Qu, C; Shi, S; Yang, B; Yang, H1
Gilbert, JR; Nugent, AC; Wills, KE; Yarrington, JS; Zarate, CA1
Farber, NB1
Beck, J; Borgwardt, S; Deutschenbaur, L; Hasler, G; Kiyhankhadiv, A; Lang, UE; Mühlhauser, M; Sollberger, D; Walter, M1
Lloyd, RL; Pekary, AE; Sattin, A1
Eby, GA; Eby, KL1
Ameli, R; Brutsche, NE; DiazGranados, N; Henter, ID; Ibrahim, LA; Luckenbaugh, DA; Machado-Vieira, R; Zarate, CA1
Baumann, J; Diazgranados, N; Ibrahim, L; Luckenbaugh, DA; Machado-Vieira, R; Mallinger, AG; Zarate, CA1
Brutsche, N; Duncan, WC; Sarasso, S; Selter, J; Zarate, CA1
Bakish, D; Beaulieu, S; Young, LT1
Magarinos, AM; McEwen, BS; Reagan, LP1
Coyle, JT; Frye, MA; Huggins, T; Post, RM; Tsai, GE1
Deakin, JF; Guimarães, FS; Oliveira, RM1

Reviews

6 review(s) available for n-methylaspartate and Depression, Involutional

ArticleYear
Importance of Exploring N-Methyl-D-Aspartate (NMDA) as a Future Perspective Target in Depression.
    CNS & neurological disorders drug targets, 2022, Volume: 21, Issue:10

    Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder, Major; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate

2022
[Ketamine: a neuropsychotropic drug with an innovative mechanism of action].
    Biologie aujourd'hui, 2023, Volume: 217, Issue:3-4

    Topics: Animals; Antidepressive Agents; Depressive Disorder, Major; Glutamic Acid; Ketamine; N-Methylaspartate; Pharmaceutical Preparations; Receptors, AMPA

2023
Role of calcium, glutamate and NMDA in major depression and therapeutic application.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, Jan-04, Volume: 64

    Topics: Animals; Antidepressive Agents; Calcium; Depressive Disorder, Major; Glutamic Acid; Humans; N-Methylaspartate; Neurogenesis; Neuronal Plasticity; Neurotransmitter Agents

2016
Magnesium for treatment-resistant depression: a review and hypothesis.
    Medical hypotheses, 2010, Volume: 74, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clinical Trials as Topic; D-Aspartic Acid; Depression; Depressive Disorder; Depressive Disorder, Major; Fast Foods; Humans; Imipramine; Magnesium; Magnesium Deficiency; Mental Disorders; Models, Neurological; N-Methylaspartate; Randomized Controlled Trials as Topic; Suicide, Attempted

2010
The neurobiology of treatment response to antidepressants and mood stabilizing medications.
    Journal of psychiatry & neuroscience : JPN, 2002, Volume: 27, Issue:4

    Topics: Adenylyl Cyclases; Antidepressive Agents; Brain; CREB-Binding Protein; Cyclic AMP; Depressive Disorder, Major; Humans; N-Methylaspartate; Nuclear Proteins; Trans-Activators

2002
Structural plasticity and tianeptine: cellular and molecular targets.
    European psychiatry : the journal of the Association of European Psychiatrists, 2002, Volume: 17 Suppl 3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents, Tricyclic; Apoptosis; Atrophy; Dentate Gyrus; Depressive Disorder, Major; Glutamic Acid; Hippocampus; Humans; N-Methylaspartate; Neuronal Plasticity; Neurons; Serotonin; Thiazepines

2002

Trials

4 trial(s) available for n-methylaspartate and Depression, Involutional

ArticleYear
No influence of mineralocorticoid and glutamatergic NMDA receptor stimulation on spatial learning and memory in individuals with major depression.
    Journal of psychiatric research, 2022, Volume: 152

    Topics: Adult; Depression; Depressive Disorder, Major; Female; Hippocampus; Humans; Male; Maze Learning; Memory; Middle Aged; Mineralocorticoids; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Spatial Learning; Spatial Memory; Young Adult

2022
Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling.
    The international journal of neuropsychopharmacology, 2018, 08-01, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Affect; Aged; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Antidepressive Agents; Brain; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Evoked Potentials, Somatosensory; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Infusions, Intravenous; Ketamine; Magnetoencephalography; Male; Middle Aged; Models, Neurological; N-Methylaspartate; Time Factors; Treatment Outcome; Young Adult

2018
Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:12

    Topics: Adult; Antidepressive Agents; Depression; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Excitatory Amino Acid Antagonists; Female; Humans; Infusions, Intravenous; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Suicidal Ideation; Time Factors; Treatment Outcome

2010
Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder.
    Journal of affective disorders, 2013, Feb-15, Volume: 145, Issue:1

    Topics: Adolescent; Adult; Affect; Aged; Antidepressive Agents; Biomarkers; Depressive Disorder, Major; Drug Resistance; Electroencephalography; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Sleep; Young Adult

2013

Other Studies

7 other study(ies) available for n-methylaspartate and Depression, Involutional

ArticleYear
Rapid onset brain plasticity at novel pharmacologic targets hypothetically drives innovations for rapid onset antidepressant actions.
    Journal of psychopharmacology (Oxford, England), 2023, Volume: 37, Issue:3

    Topics: Antidepressive Agents; Depressive Disorder, Major; gamma-Aminobutyric Acid; Hallucinogens; Humans; N-Methylaspartate; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate

2023
The activation of
    American journal of physiology. Cell physiology, 2017, Aug-01, Volume: 313, Issue:2

    Topics: Action Potentials; Animals; Calcium; Calcium Channels, L-Type; Depressive Disorder, Major; Disease Models, Animal; Dizocilpine Maleate; Heart Ventricles; Humans; Myocytes, Cardiac; N-Methylaspartate; Patch-Clamp Techniques; Potassium; Rats; Receptors, N-Methyl-D-Aspartate; Shal Potassium Channels

2017
NMDA Antagonists for Treatment-Resistant Depression.
    Handbook of experimental pharmacology, 2019, Volume: 250

    Topics: Depression; Depressive Disorder, Major; Humans; Ketamine; N-Methylaspartate; Pilot Projects

2019
Ketamine modulates TRH and TRH-like peptide turnover in brain and peripheral tissues of male rats.
    Peptides, 2015, Volume: 69

    Topics: Animals; Brain; Depressive Disorder, Major; Humans; Ketamine; Male; N-Methylaspartate; Peptides; Rats; Rats, Sprague-Dawley; Suicide; Thyrotropin-Releasing Hormone

2015
Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jun-01, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Aged; Depressive Disorder, Major; Electroconvulsive Therapy; Excitatory Amino Acid Antagonists; Female; Humans; Injections, Intravenous; Ketamine; Linear Models; Male; Middle Aged; N-Methylaspartate; Psychiatric Status Rating Scales; Sample Size; Socioeconomic Factors; Treatment Failure; Young Adult

2011
Low cerebrospinal fluid glutamate and glycine in refractory affective disorder.
    Biological psychiatry, 2007, Jan-15, Volume: 61, Issue:2

    Topics: Adult; Anticonvulsants; Antidepressive Agents; Antimanic Agents; Aspartic Acid; Bipolar Disorder; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Drug Resistance; Electroconvulsive Therapy; Female; Glutamic Acid; Glycine; Humans; Male; Middle Aged; N-Methylaspartate; Statistics as Topic

2007
Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2008, Volume: 41, Issue:4

    Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Hippocampus; Humans; Immunohistochemistry; Male; Middle Aged; N-Methylaspartate; Nitric Oxide Synthase Type I; Schizophrenia; Signal Transduction

2008