Page last updated: 2024-08-22

n-methylaspartate and Cryptogenic Infantile Spasms

n-methylaspartate has been researched along with Cryptogenic Infantile Spasms in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (12.50)18.2507
2000's4 (16.67)29.6817
2010's12 (50.00)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Banka, S; Basu, H; Blakes, AJM; English, J1
Janicot, R; Shao, LR; Stafstrom, CE1
Chern, CJ; Chern, CR; Chodounská, H; Kudová, E; Lauková, M; Schonwald, A; Shakarjian, MP; Velíšek, L; Velíšková, J1
Chachua, T; Chern, CR; Velíšek, L; Velíšková, J1
Li, Z; Shi, X; Sun, Y; Wan, L; Wang, J; Yang, G; Zhang, S1
Baba, S; Hamada, N; Ito, H; Iwamoto, I; Kato, M; Maki, Y; Maruyama, K; Matsumoto, N; Momiyama, T; Nagata, KI; Nakashima, M; Nishijo, T; Ogaya, S; Saitsu, H; Shirai, K; Sugawara, Y1
Chern, CJ; Chern, CR; Velíšek, L; Velíšková, J1
Shang, AJ; Wang, J; Yang, G; Zhang, Y; Zou, LP1
Ko, TS; Lee, M; Velíšek, L; Yum, MS1
Kim, DW; Ko, TS; Lee, M; Velíšek, L; Woo, DC; Yum, MS1
Hirose, S; Hu, LY; Ju, J; Shi, XY; Tomonoh, Y; Yang, XF; Zou, LP1
Ju, J; Shang, NX; Shi, XY; Wang, J; Zhang, JY; Zhao, JB; Zou, LP1
Kubová, H; Mares, P1
Chachua, T; Poon, KL; Velísek, L; Velísková, J; Yum, MS1
Chachua, T; Velíšek, L; Velíšková, J; Yum, MS1
Ding, YX; Shi, XY; Yang, G; Zou, LP1
Shang, AJ; Wang, J; Yang, G; Zhang, Y; Zhou, WJ; Zou, LP1
Rho, JM1
Chen, K; Mix, E; Wang, HM; Zen, M; Zhang, WH; Zou, LP1
Asche, S; Jehle, K; Velísek, L; Velísková, J1
Kábová, R; Velísek, L; Veresová, S1
Kábová, R; Liptáková, S; Pometlová, M; Slamberová, R; Velísek, L1
Holmes, GL; Stafstrom, CE1
Buchwald, NA; Cepeda, C; Dudek, FE; Kim, YI; Peacock, WJ; Tasker, JG; Walsh, JP; Wuarin, JP1

Reviews

3 review(s) available for n-methylaspartate and Cryptogenic Infantile Spasms

ArticleYear
A homozygous GRIN1 null variant causes a more severe phenotype of early infantile epileptic encephalopathy.
    American journal of medical genetics. Part A, 2022, Volume: 188, Issue:2

    Topics: Epilepsy; Humans; Infant; N-Methylaspartate; Nerve Tissue Proteins; Phenotype; Receptors, N-Methyl-D-Aspartate; Spasms, Infantile

2022
Basic science behind the catastrophic epilepsies.
    Epilepsia, 2004, Volume: 45 Suppl 5

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Corticotropin-Releasing Hormone; Epilepsies, Myoclonic; Epilepsy; Humans; Infant; Infant, Newborn; Kynurenic Acid; Kynurenine; N-Methylaspartate; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Serotonin; Spasms, Infantile; Tryptophan

2004
Infantile spasms: criteria for an animal model.
    International review of neurobiology, 2002, Volume: 49

    Topics: Adrenocorticotropic Hormone; Aging; Anticonvulsants; Corticotropin-Releasing Hormone; Disease Models, Animal; Electroencephalography; Humans; Infant; N-Methylaspartate; Sleep Stages; Spasms, Infantile; Wakefulness

2002

Other Studies

21 other study(ies) available for n-methylaspartate and Cryptogenic Infantile Spasms

ArticleYear
2-deoxyglucose and β-hydroxybutyrate fail to attenuate seizures in the betamethasone-NMDA model of infantile spasms.
    Epilepsia open, 2022, Volume: 7, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Deoxyglucose; Disease Models, Animal; Female; N-Methylaspartate; Pregnancy; Rats; Seizures; Spasm; Spasms, Infantile

2022
Novel neurosteroid pregnanolone pyroglutamate suppresses neurotoxicity syndrome induced by tetramethylenedisulfotetramine but is ineffective in a rodent model of infantile spasms.
    Pharmacological reports : PR, 2023, Volume: 75, Issue:1

    Topics: Animals; Diazepam; Glutamic Acid; N-Methylaspartate; Neurosteroids; Neurotoxicity Syndromes; Pregnanolone; Pyrrolidonecarboxylic Acid; Rodentia; Spasm; Spasms, Infantile

2023
Epileptic spasms in infancy: Transferring rat prenatal betamethasone-postnatal NMDA model to mice.
    Neuroscience letters, 2023, 09-14, Volume: 813

    Topics: Adrenocorticotropic Hormone; Animals; Betamethasone; Disease Models, Animal; Female; Mice; Mice, Inbred C57BL; N-Methylaspartate; Pregnancy; Rats; Spasms, Infantile

2023
Combined melatonin and adrenocorticotropic hormone treatment attenuates N-methyl-d-aspartate-induced infantile spasms in a rat model by regulating activation of the HPA axis.
    Neuroscience letters, 2021, 03-23, Volume: 748

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Anticonvulsants; Disease Models, Animal; Humans; Hypothalamo-Hypophyseal System; Infant; Melatonin; N-Methylaspartate; Pituitary-Adrenal System; Rats, Sprague-Dawley; Spasms, Infantile

2021
De novo PHACTR1 mutations in West syndrome and their pathophysiological effects.
    Brain : a journal of neurology, 2018, 11-01, Volume: 141, Issue:11

    Topics: Animals; Cell Movement; Cells, Cultured; Chlorocebus aethiops; COS Cells; Embryo, Mammalian; Excitatory Amino Acid Agonists; Family Health; Female; Humans; Infant; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Mice, Transgenic; Microfilament Proteins; Mutation; N-Methylaspartate; Neuronal Plasticity; Neurons; Spasms, Infantile; Urea

2018
AQB-565 shows promise in preclinical testing in the model of epileptic spasms during infancy: Head-to-head comparison with ACTH.
    Epilepsy research, 2019, Volume: 152

    Topics: Adrenocorticotropic Hormone; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Female; Humans; Infant; Male; Melanocyte-Stimulating Hormones; N-Methylaspartate; Peptides; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Spasms, Infantile; Treatment Outcome

2019
Proteomic analysis on infantile spasm and prenatal stress.
    Epilepsy research, 2014, Volume: 108, Issue:7

    Topics: 14-3-3 Proteins; Animals; Cofilin 1; Computational Biology; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Humans; Infant; Male; Molecular Chaperones; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Protein Interaction Maps; Proteomics; Rats; Rats, Wistar; Spasms, Infantile; Stress, Psychological; Two-Dimensional Difference Gel Electrophoresis

2014
A potential effect of ganaxolone in an animal model of infantile spasms.
    Epilepsy research, 2014, Volume: 108, Issue:9

    Topics: Age Factors; Anesthetics; Animals; Animals, Newborn; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Humans; Infant; Male; N-Methylaspartate; Pregnanolone; Rats; Rats, Sprague-Dawley; Reaction Time; Social Behavior; Spasms, Infantile; Statistics, Nonparametric

2014
β-Hydroxybutyrate attenuates NMDA-induced spasms in rats with evidence of neuronal stabilization on MR spectroscopy.
    Epilepsy research, 2015, Volume: 117

    Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Brain; Disease Models, Animal; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; N-Methylaspartate; Rats; Seizures; Spasms, Infantile; Treatment Outcome

2015
Development of a mouse model of infantile spasms induced by N-methyl-D-aspartate.
    Epilepsy research, 2015, Volume: 118

    Topics: Adrenocorticotropic Hormone; Age Factors; Animals; Animals, Newborn; Anticonvulsants; Disease Models, Animal; Electroencephalography; Excitatory Amino Acid Agonists; Exploratory Behavior; Female; Humans; Infant; Learning Disabilities; Male; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; N-Methylaspartate; Psychomotor Performance; Spasms, Infantile; Species Specificity; Video Recording

2015
Increased precipitation of spasms in an animal model of infantile spasms by prenatal stress exposure.
    Life sciences, 2016, May-01, Volume: 152

    Topics: Adrenocorticotropic Hormone; Animals; Brain; Cold Temperature; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Hormones; Humans; Infant; Infant, Newborn; Male; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Receptors, Neurotransmitter; Spasms, Infantile; Stress, Psychological; Swimming

2016
Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Age Factors; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Epilepsy, Tonic-Clonic; Humans; Infant; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Spasms, Infantile; Valproic Acid; Vigabatrin

2010
Model of cryptogenic infantile spasms after prenatal corticosteroid priming.
    Epilepsia, 2010, Volume: 51 Suppl 3

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Brain Stem; Disease Models, Animal; Electroencephalography; Hippocampus; Humans; Hypothalamus; Infant; N-Methylaspartate; Rats; Spasms, Infantile

2010
Validation of the rat model of cryptogenic infantile spasms.
    Epilepsia, 2011, Volume: 52, Issue:9

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Disease Models, Animal; Electroencephalography; Exploratory Behavior; Female; GABA Agents; Glucocorticoids; Humans; Infant, Newborn; Male; Maze Learning; Methylprednisolone; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spasms, Infantile; Time Factors; Vigabatrin

2011
Prenatal stress exposure hypothesis for infantile spasms.
    Medical hypotheses, 2012, Volume: 78, Issue:6

    Topics: Animals; Case-Control Studies; Cold Temperature; Female; Humans; Infant, Newborn; Models, Biological; N-Methylaspartate; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Spasms, Infantile; Stress, Physiological

2012
Proteomic analysis of adrenocorticotropic hormone treatment of an infantile spasm model induced by N-methyl-D-aspartic acid and prenatal stress.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Infant, Newborn; N-Methylaspartate; Pregnancy; Proteome; Proteomics; Spasms, Infantile; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stress, Physiological

2012
Maternal IgG suppresses NMDA-induced spasms in infant rats and inhibits NMDA-mediated neurotoxicity in hippocampal neurons.
    Journal of neuroimmunology, 2006, Volume: 181, Issue:1-2

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Suckling; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Hippocampus; Humans; Immunoglobulin G; Immunotherapy; Infant, Newborn; Male; Milk; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Spasms, Infantile

2006
Model of infantile spasms induced by N-methyl-D-aspartic acid in prenatally impaired brain.
    Annals of neurology, 2007, Volume: 61, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Brain; Deoxyglucose; Disease Models, Animal; Drug Administration Schedule; Drug Synergism; Electroencephalography; Female; Fetus; Gestational Age; Glucocorticoids; Humans; Immunohistochemistry; Infant, Newborn; N-Methylaspartate; Pregnancy; Proto-Oncogene Proteins c-fos; Rats; Spasms, Infantile

2007
West syndrome model: seek and you will find.
    Sbornik lekarsky, 1997, Volume: 98, Issue:2

    Topics: Animals; Disease Models, Animal; Electroencephalography; Excitatory Amino Acid Antagonists; Humans; Infant; N-Methylaspartate; Rats; Spasms, Infantile

1997
Age-specific N-methyl-D-aspartate-induced seizures: perspectives for the West syndrome model.
    Epilepsia, 1999, Volume: 40, Issue:10

    Topics: Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Electroencephalography; Humans; Hydrocortisone; N-Methylaspartate; Pyridoxine; Rats; Seizures; Spasms, Infantile; Valproic Acid

1999
Synaptic transmission in human neocortex removed for treatment of intractable epilepsy in children.
    Annals of neurology, 1990, Volume: 28, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Adolescent; Bicuculline; Child; Child, Preschool; Epilepsy; Female; GABA Antagonists; Humans; Infant; Kynurenic Acid; Male; Membrane Potentials; N-Methylaspartate; Psychosurgery; Pyramidal Tracts; Spasms, Infantile; Synapses; Synaptic Transmission

1990