Page last updated: 2024-08-22

n-methylaspartate and Cognition Disorders

n-methylaspartate has been researched along with Cognition Disorders in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.94)	18.7374
1990's	5 (14.71)	18.2507
2000's	13 (38.24)	29.6817
2010's	14 (41.18)	24.3611
2020's	1 (2.94)	2.80

Authors

Authors	Studies
Jones, NC; Lee, J; Nithianantharajah, J; van den Buuse, M	1
Elefant, F; Gao, WJ; Gulchina, Y; Snyder, MA; Xu, SJ	1
Bott, JB; Cassel, JC; Cosquer, B; Héraud, C; Kelche, C; Mathis, C; Zerbinatti, C	1
Mattson, MP; Wang, Y	1
Beste, C; Humphries, M; Saft, C	1
Chen, L; Chen, T; Hong, J; Jie, P; Li, L; Sha, S; Sokabe, M; Wang, C; Yin, J; Zhou, R	1
Çalişir, M; Gürgen, SG; Sayın, O; Sönmez, A	1
Chao, OY; de Souza Silva, MA; Huston, JP; Petri, D; Schnitzler, A	1
Arias-Carrión, O; Caixeta, L; Campos, C; Machado, S; Nardi, AE; Paes, F; Rocha, NB; Rocha, SA; Telles-Correia, D; Vieira, RT; Yuan, T	1
Bitik, B; Goker, B; Haznedaroglu, S; Irkec, C; Kocer, EB; Mercan, R; Sonmez, C; Tezcan, ME; Yucel, AA	1
Bi, Y; Fan, G; Feng, C; Lin, F; Wang, C; Wu, F; Xiao, Y; Yan, J; Ye, W; Zhu, G	1
Ben Abdallah, NM; Bobsin, K; Colacicco, G; Deacon, RM; Fuss, J; Galsworthy, MJ; Gass, P; Kellendonk, C; Lipp, HP; Riva, MA; Sprengel, R; Trusel, M	1
Kodama, D; Ono, H; Tanabe, M	1
Cho, IH; Hong, HS; Kim, HS; Lee, CK; Lee, JM; Lee, KS; Noh, SJ; Suh, YH	1
Chou, HH; Swerdlow, NR; Twamley, E	1
Sasaki-Adams, DM; Stafstrom, CE	1
Qin, YH; Song, LH; Wang, L; Zhang, HS	1
Hori, K; Kobayashi, M; Masaki, T; Masuo, Y; Miyamoto, M; Noguchi, H; Nomura, M; Takamatsu, K; Tsubokawa, H	1
Gourevitch, R	1
Kandel, ER; Kellendonk, C; Malleret, G; Moore, H; Polan, HJ; Simpson, EH; Vronskaya, S; Winiger, V	1
Bigelow, L; Callicott, JH; Coppola, R; Egan, MF; Goldberg, TE; Hariri, A; Mattay, VS; Straub, RE; Weinberger, DR	1
Chafee, MV; MacDonald, AW	1
Grosjean, B; Tsai, GE	1
Belger, A; van der Stelt, O	1
Felszeghy, K; Horváth, J; Kasza, A; Kurunczi, A; Laroche, S; Párducz, A; Penke, B; Penke, Z; Sipos, E; Toldi, J	1
Tsai, GE	1
Javitt, DC	1
Ilivitsky, V; Jones, BD; Mohr, E; Purdon, SE	1
Hyvönen, M; Lahtinen, H; Miettinen, R; Riekkinen, PJ; Sirviö, J; Ylinen, A	1
Breier, A	1
Bordi, F; Reggiani, A; Terron, A	1
Delahunty, TM; Hamm, RJ; Lyeth, BG; Phillips, LL; Povlishock, JT; Temple, MD	1
Everitt, BJ; Muir, JL; Robbins, TW; Roberts, AC	1
Rogers, BC; Tilson, HA	1

Reviews

7 review(s) available for n-methylaspartate and Cognition Disorders

Article	Year
Treatment of Cognitive Deficits in Alzheimer's disease: A psychopharmacological review. Psychiatria Danubina, 2016, Volume: 28, Issue:1 Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Humans; N-Methylaspartate	2016
Towards medication-enhancement of cognitive interventions in schizophrenia. Handbook of experimental pharmacology, 2012, Issue:213 Topics: Antipsychotic Agents; Biomarkers; Cognition Disorders; Electroencephalography; Humans; N-Methylaspartate; Neuropsychological Tests; Schizophrenia; Schizophrenic Psychology	2012
Translational and developmental perspective on N-methyl-D-aspartate synaptic deficits in schizophrenia. Development and psychopathology, 2006,Summer, Volume: 18, Issue:3 Topics: Carrier Proteins; Cognition Disorders; Dysbindin; Dystrophin-Associated Proteins; Humans; Interdisciplinary Communication; Intracellular Signaling Peptides and Proteins; N-Methylaspartate; Nerve Net; Nerve Tissue Proteins; Neuregulin-1; Neuronal Plasticity; Prefrontal Cortex; Presynaptic Terminals; Psychological Theory; Receptors, Metabotropic Glutamate; RGS Proteins; Schizophrenia; Signal Transduction; Social Behavior	2006
NMDA neurotransmission as a critical mediator of borderline personality disorder. Journal of psychiatry & neuroscience : JPN, 2007, Volume: 32, Issue:2 Topics: Borderline Personality Disorder; Brain; Cognition Disorders; Humans; Life Change Events; Memory Disorders; N-Methylaspartate; Neuronal Plasticity; Psychotherapy; Receptors, N-Methyl-D-Aspartate; Risk Factors; Social Environment; Synaptic Transmission	2007
Application of electroencephalography to the study of cognitive and brain functions in schizophrenia. Schizophrenia bulletin, 2007, Volume: 33, Issue:4 Topics: Catechol O-Methyltransferase; Cognition Disorders; Electroencephalography; Event-Related Potentials, P300; gamma-Aminobutyric Acid; Gene Expression; Humans; N-Methylaspartate; Schizophrenia	2007
Huntington's disease: pathogenesis, diagnosis and treatment. Journal of psychiatry & neuroscience : JPN, 1994, Volume: 19, Issue:5 Topics: Adult; Brain; Cognition Disorders; Diagnostic Imaging; Eye Movements; Female; Fetal Tissue Transplantation; Humans; Huntington Disease; Male; N-Methylaspartate; Neuropsychological Tests; Palliative Care	1994
Cognitive deficit in schizophrenia and its neurochemical basis. The British journal of psychiatry. Supplement, 1999, Issue:37 Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Cognition Disorders; Glutamic Acid; Haloperidol; Humans; N-Methylaspartate; Olanzapine; Pirenzepine; Risperidone; Schizophrenia; Schizophrenic Psychology	1999

Other Studies

27 other study(ies) available for n-methylaspartate and Cognition Disorders

Article	Year
Acute NMDA receptor antagonism impairs working memory performance but not attention in rats-Implications for the NMDAr hypofunction theory of schizophrenia. Behavioral neuroscience, 2020, Volume: 134, Issue:4 Topics: Animals; Antipsychotic Agents; Attention; Cognition; Cognition Disorders; Cognitive Dysfunction; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Memory, Short-Term; N-Methylaspartate; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2020
Epigenetic mechanisms underlying NMDA receptor hypofunction in the prefrontal cortex of juvenile animals in the MAM model for schizophrenia. Journal of neurochemistry, 2017, Volume: 143, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cognition Disorders; Disease Models, Animal; Epigenesis, Genetic; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation, Developmental; In Vitro Techniques; Male; Methylazoxymethanol Acetate; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Pregnancy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia	2017
Reduced plasticity and mild cognitive impairment-like deficits after entorhinal lesions in hAPP/APOE4 mice. Neurobiology of aging, 2013, Volume: 34, Issue:11 Topics: Age Factors; Amyloid beta-Protein Precursor; Animals; Apolipoprotein E4; Atrophy; Brain Injuries; Cognition Disorders; Dark Adaptation; Entorhinal Cortex; Excitatory Amino Acids; Gene Expression Regulation; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Recognition, Psychology; Synapses	2013
L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner. Neurobiology of aging, 2014, Volume: 35, Issue:1 Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Calcium Channels, L-Type; Cells, Cultured; Cognition Disorders; Dentate Gyrus; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Patch-Clamp Techniques; Phosphorylation; Potassium Channels, Voltage-Gated; Synapses; tau Proteins	2014
Striatal disorders dissociate mechanisms of enhanced and impaired response selection - Evidence from cognitive neurophysiology and computational modelling. NeuroImage. Clinical, 2014, Volume: 4 Topics: Acoustic Stimulation; Adult; Analysis of Variance; Cognition Disorders; Computer Simulation; Contingent Negative Variation; Corpus Striatum; Decision Making; Discrimination, Psychological; Electroencephalography; Excitatory Amino Acid Agonists; Female; Humans; Huntington Disease; Male; Models, Neurological; N-Methylaspartate; Nerve Net; Neurons; Neuropsychological Tests; Young Adult	2014
Sigma-1 (σ₁) receptor deficiency reduces β-amyloid(25-35)-induced hippocampal neuronal cell death and cognitive deficits through suppressing phosphorylation of the NMDA receptor NR2B. Neuropharmacology, 2015, Volume: 89 Topics: Amyloid beta-Peptides; Animals; Apoptosis; Cell Death; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Agents; Hippocampus; Male; Maze Learning; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Peptide Fragments; Phosphorylation; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Spatial Memory; Time Factors	2015
Neuroprotective effects of MK-801 against traumatic brain injury in immature rats. Neuroscience letters, 2015, Jun-15, Volume: 597 Topics: Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; Cognition Disorders; Dizocilpine Maleate; Hippocampus; Memory; N-Methylaspartate; Nerve Growth Factor; Neurons; Neuroprotective Agents; Rats, Wistar	2015
Serotonergic interaction between medial prefrontal cortex and mesotelencephalic DA system underlies cognitive and affective deficits in hemiparkinsonian rats. Neuroscience, 2015, Oct-29, Volume: 307 Topics: Adrenergic Agents; Animals; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Agonists; Functional Laterality; Male; Maze Learning; Mood Disorders; Motor Activity; N-Methylaspartate; Oxidopamine; Parkinsonian Disorders; Prefrontal Cortex; Rats; Rats, Wistar; Sensory Gating; Telencephalon	2015
Primary Sjögren's syndrome is associated with significant cognitive dysfunction. International journal of rheumatic diseases, 2016, Volume: 19, Issue:10 Topics: Adult; Attention; Autoantibodies; Biomarkers; Case-Control Studies; Cognition; Cognition Disorders; Executive Function; Female; Gangliosides; Humans; Memory; Middle Aged; N-Methylaspartate; Neuropsychological Tests; Registries; Ribosomal Proteins; Sjogren's Syndrome; Space Perception; Visual Perception	2016
Methionine choline reverses lead-induced cognitive and N-methyl-d-aspartate receptor subunit 1 deficits. Toxicology, 2010, Jun-04, Volume: 272, Issue:1-3 Topics: Animals; Brain; Choline; Cognition Disorders; D-Aspartic Acid; Hippocampus; Male; Memory; Methionine; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; RNA, Messenger	2010
The puzzle box as a simple and efficient behavioral test for exploring impairments of general cognition and executive functions in mouse models of schizophrenia. Experimental neurology, 2011, Volume: 227, Issue:1 Topics: Animals; Behavior, Animal; Cognition Disorders; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Executive Function; Gene Expression Regulation; Hippocampus; Kaplan-Meier Estimate; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Prefrontal Cortex; Problem Solving; Reaction Time; Receptors, AMPA; Receptors, Dopamine D2; Schizophrenia	2011
Increased hippocampal glycine uptake and cognitive dysfunction after peripheral nerve injury. Pain, 2011, Volume: 152, Issue:4 Topics: Animals; Cognition Disorders; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Exploratory Behavior; Fluoroacetates; Glycine; Herb-Drug Interactions; Hippocampus; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Motor Activity; N-Methylaspartate; Neurons; Pain Measurement; Pain Threshold; Patch-Clamp Techniques; Recognition, Psychology; Sarcosine; Sciatic Neuropathy	2011
SP-8203 shows neuroprotective effects and improves cognitive impairment in ischemic brain injury through NMDA receptor. Pharmacology, biochemistry, and behavior, 2011, Volume: 100, Issue:1 Topics: Acetamides; Animals; Animals, Newborn; Brain Injuries; Brain Ischemia; Cells, Cultured; Cognition Disorders; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neuroprotective Agents; Quinazolinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2011
NMDA-induced seizures in developing rats cause long-term learning impairment and increased seizure susceptibility. Epilepsy research, 2003, Volume: 53, Issue:1-2 Topics: Animals; Animals, Newborn; Brain; Cognition Disorders; Convulsants; Electroencephalography; Excitatory Amino Acid Agonists; Learning Disabilities; Maze Learning; N-Methylaspartate; Neurons; Pentylenetetrazole; Phenotype; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus	2003
Lead can inhibit NMDA-, K(+)-, QA/KA-induced increases in intracellular free Ca2+ in cultured rat hippocampal neurons. Biomedical and environmental sciences : BES, 2002, Volume: 15, Issue:4 Topics: Animals; Calcium; Cognition Disorders; Disease Models, Animal; Hippocampus; Kainic Acid; Lead; Learning Disabilities; Microscopy, Confocal; N-Methylaspartate; Neurons; Potassium; Quisqualic Acid; Rats; Rats, Wistar	2002
Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory. Neuroscience, 2005, Volume: 133, Issue:2 Topics: Animals; Association Learning; Avoidance Learning; Behavior, Animal; Blotting, Western; Brain; Cadmium Chloride; Calcium Channel Blockers; Calcium-Binding Proteins; Choice Behavior; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Discrimination Learning; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavonoids; Hippocalcin; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Nimodipine; Phosphorylation; Potassium Chloride; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Spatial Behavior; Valine	2005
[Neurobiological aspects of bipolar disorder]. L'Encephale, 2005, Volume: 31, Issue:Pt 2 Topics: Amygdala; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Cognition Disorders; Diagnosis, Differential; Hippocampus; Humans; N-Methylaspartate; Neuropsychological Tests; Prefrontal Cortex; Psychotic Disorders; Schizophrenia	2005
Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning. Neuron, 2006, Feb-16, Volume: 49, Issue:4 Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Behavior, Animal; Carbon Isotopes; Cognition Disorders; Corpus Striatum; Deoxyglucose; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Doxycycline; Excitatory Amino Acid Agonists; Gene Expression; Glucose; Humans; Immunohistochemistry; In Situ Hybridization; Male; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; N-Methylaspartate; Prefrontal Cortex; Protein Binding; Proto-Oncogene Proteins c-fos; Radioligand Assay; Reaction Time; Receptors, Dopamine D2; Spiperone; Time Factors; Tritium	2006
The G72/G30 gene complex and cognitive abnormalities in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:9 Topics: Adult; Alleles; Carrier Proteins; Chromosomes; Cognition; Cognition Disorders; Female; Genotype; Haplotypes; Humans; Intelligence Tests; Intracellular Signaling Peptides and Proteins; Linkage Disequilibrium; Magnetic Resonance Imaging; Male; N-Methylaspartate; Neuropsychological Tests; Oxygen; Polymorphism, Single Nucleotide; Schizophrenic Psychology; Signal Transduction; Synaptic Transmission; Temporal Lobe	2006
Beta-amyloid pathology in the entorhinal cortex of rats induces memory deficits: implications for Alzheimer's disease. Neuroscience, 2007, Jun-15, Volume: 147, Issue:1 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition Disorders; Disease Models, Animal; Entorhinal Cortex; Exploratory Behavior; Gliosis; Male; Maze Learning; Microinjections; N-Methylaspartate; Neurotoxins; Peptide Fragments; Plaque, Amyloid; Rats; Rats, Wistar; Recognition, Psychology; Statistics, Nonparametric	2007
Searching for rational anti N-methyl-D-aspartate treatment for depression. Archives of general psychiatry, 2007, Volume: 64, Issue:9 Topics: Cognition Disorders; Depressive Disorder; Excitatory Amino Acid Antagonists; Humans; Ketamine; N-Methylaspartate; Neurodegenerative Diseases; Psychoses, Substance-Induced; Receptors, N-Methyl-D-Aspartate	2007
Phenomenology, aetiology and treatment of schizophrenia. Novartis Foundation symposium, 2008, Volume: 289 Topics: Cognition Disorders; Growth Substances; Hearing Disorders; Humans; N-Methylaspartate; Schizophrenia; Schizophrenic Psychology	2008
Preservation of hippocampal NMDA receptors may be crucial for spatial learning after epileptic seizures in rats. Brain research, 1993, Oct-15, Volume: 625, Issue:1 Topics: 2-Amino-5-phosphonovalerate; Animals; Cognition Disorders; Electric Stimulation; Epilepsy; Glutamates; Glutamic Acid; Hippocampus; Learning; Male; N-Methylaspartate; Neurons; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Somatostatin; Space Perception	1993
The neuroprotective glycine receptor antagonist GV150526 does not produce neuronal vacuolization or cognitive deficits in rats. European journal of pharmacology, 1999, Aug-06, Volume: 378, Issue:2 Topics: Action Potentials; Animals; Brain; Cerebral Cortex; Cognition Disorders; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; Indoles; Male; Maze Learning; N-Methylaspartate; Neurons; Neuroprotective Agents; Perforant Pathway; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Time Factors; Vacuoles	1999
Subtle alterations in NMDA-stimulated cyclic GMP levels following lateral fluid percussion brain injury. Journal of neurotrauma, 2001, Volume: 18, Issue:1 Topics: Animals; Brain Injuries; Cognition Disorders; Cyclic GMP; Disease Models, Animal; Functional Laterality; Hippocampus; Male; N-Methylaspartate; Percussion; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors	2001
A specific form of cognitive rigidity following excitotoxic lesions of the basal forebrain in marmosets. Neuroscience, 1992, Volume: 47, Issue:2 Topics: Animals; Callithrix; Choline O-Acetyltransferase; Cognition; Cognition Disorders; Discrimination Learning; Discrimination, Psychological; Female; Histocytochemistry; Male; N-Methylaspartate; Parasympathetic Nervous System; Prosencephalon; Reversal Learning; Substantia Innominata; Vision, Ocular	1992
MK-801 prevents cognitive and behavioral deficits produced by NMDA receptor overstimulation in the rat hippocampus. Toxicology and applied pharmacology, 1989, Volume: 99, Issue:3 Topics: Animals; Aspartic Acid; Behavior, Animal; Cognition Disorders; Dibenzocycloheptenes; Dizocilpine Maleate; Hippocampus; Male; N-Methylaspartate; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1989